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Title

Reported Case Report of Recovery From Rabies Using Intrathecal Rabies Immune Globulin was Flawed.

Authors

Jackson, Alan C.; Rupprecht, Charles E.; Mani, Reeta S.; Aréchiga-Ceballos, Nidia; Knobel, Darryn L.

Abstract

The letter published in the Canadian Journal of Neurological Sciences critiques a reported case of recovery from rabies using intrathecal rabies immune globulin, highlighting numerous flaws in the treatment approach. Concerns are raised about the lack of compliance with World Health Organization recommendations, insufficient details about the case, and questionable laboratory evaluations. The authors recommend caution in considering similar treatment approaches due to uncertainties surrounding the reported case and the delivery method of intrathecal RIG.

Subjects

CENTRAL nervous system infections; VACCINE trials; DORSAL root ganglia; RABIES vaccines; INTRATHECAL injections

Publication

Canadian Journal of Neurological Sciences, 2024, Vol 51, Issue 6, p868

ISSN

0317-1671

Publication type

Academic Journal

DOI

10.1017/cjn.2023.319

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