Works matching DE "POLYKETIDES"

Results: 1637

Polyketides with a 6/6/6/6 Oxaphenalene Pyranone Skeleton from Marine-Derived Streptomyces sp. HDN150000.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 188, doi. 10.3390/md23050188

By:

Zhang, Xiaoting;
Zhang, Falei;
Wang, Wenxue;
Ren, Xingtao;
Zhu, Tianjiao;
Che, Qian;
Li, Dehai;
Zhang, Guojian

Publication type:

Article

New insights into the formation of fungal aromatic polyketides.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 12, p. 879, doi. 10.1038/nrmicro2465

By:

Crawford, Jason M.;
Townsend, Craig A.

Publication type:

Article

Fungal metabolism: Completing the circle.

Published in:

Nature Reviews Microbiology, 2009, v. 7, n. 12, p. 842, doi. 10.1038/nrmicro2276

By:

Molloy, Sheilagh

Publication type:

Article

Fungal metabolism: Dissecting catalysis.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 6, p. 414, doi. 10.1038/nrmicro1917z

By:

Smallridge, Rachel

Publication type:

Article

New tricks for E. coli?

Published in:

Nature Reviews Microbiology, 2006, v. 4, n. 10, p. 722, doi. 10.1038/nrmicro1513

By:

Molloy, Sheilagh

Publication type:

Article

Combinatorial biosynthesis of reduced polyketides.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 12, p. 925, doi. 10.1038/nrmicro1287

By:

Weissman, Kira J.;
Leadlay, Peter F.

Publication type:

Article

Reductive Release from a Hybrid PKS‐NRPS during the Biosynthesis of Pyrichalasin H.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 4, p. 1, doi. 10.1002/chem.202302590

By:

Heinemann, Henrike;
Zhang, Haili;
Cox, Russell J.

Publication type:

Article

A Common C2‐Symmetric 2,2'‐Biphenol Building Block and its Application in the Synthesis of (+)‐di‐epi‐Gonytolide A.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 34, p. 1, doi. 10.1002/chem.202300941

By:

Greb, Julian;
Drennhaus, Till;
Klischan, Moritz K. T.;
Schroeder, Zachary W.;
Frey, Wolfgang;
Pietruszka, Jörg

Publication type:

Article

Modifications of Acyl Carrier Protein‐Bound Glycosylated Polyketides in Pactamycin Biosynthesis.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 33, p. 1, doi. 10.1002/chem.202301056

By:

Eida, Auday A.;
Samadi, Arash;
Tsunoda, Takeshi;
Mahmud, Taifo

Publication type:

Article

Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202202164

By:

Grigalunas, Michael;
Patil, Sohan;
Krzyzanowski, Adrian;
Pahl, Axel;
Flegel, Jana;
Schölermann, Beate;
Xie, Jianing;
Sievers, Sonja;
Ziegler, Slava;
Waldmann, Herbert

Publication type:

Article

Total Synthesis and Structural Assignment of (−)‐Fusaequisin A.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 5, p. 1, doi. 10.1002/chem.202103558

By:

Schmidt, Ann‐Christin;
Hiersemann, Martin

Publication type:

Article

Cover Feature: Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varing and Rare Heterocycles[] (Chem. Eur. J. 67/2021).

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 67, p. 16528, doi. 10.1002/chem.202104027

By:

Popoff, Alexander;
Hug, Joachim J.;
Walesch, Sebastian;
Garcia, Ronald;
Keller, Lena;
Müller, Rolf

Publication type:

Article

Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varing and Rare Heterocycles[]**.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 67, p. 16654, doi. 10.1002/chem.202103095

By:

Popoff, Alexander;
Hug, Joachim J.;
Walesch, Sebastian;
Garcia, Ronald;
Keller, Lena;
Müller, Rolf

Publication type:

Article

Total Synthesis and Bioactivity Mapping of Geodiamolide H.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 45, p. 11633, doi. 10.1002/chem.202100989

By:

Nasufović, Veselin;
Küllmer, Florian;
Bößneck, Johanna;
Dahse, Hans‐Martin;
Görls, Helmar;
Bellstedt, Peter;
Stallforth, Pierre;
Arndt, Hans‐Dieter

Publication type:

Article

A Straightforward Synthesis of Polyketides via Ester Dienolate Matteson Homologation.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 3, p. 949, doi. 10.1002/chem.202004650

By:

Andler, Oliver;
Kazmaier, Uli

Publication type:

Article

A Photoactivatable Small‐Molecule Probe for the In Vivo Capture of Polyketide Intermediates.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 72, p. 16511, doi. 10.1002/chem.201903661

By:

Kilgour, Samantha L.;
Jenkins, Robert;
Tosin, Manuela

Publication type:

Article

A Light‐Activated Acyl Carrier Protein "Trap" for Intermediate Capture in Type II Iterative Polyketide Biocatalysis.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 72, p. 16515, doi. 10.1002/chem.201903662

By:

Kilgour, Samantha L.;
Kilgour, David P. A.;
Prasongpholchai, Panward;
O'Connor, Peter B.;
Tosin, Manuela

Publication type:

Article

Biomimetic Total Synthesis of Hyperjapones A-E and Hyperjaponols A and C.

Published in:

Angewandte Chemie, 2016, v. 128, n. 35, p. 10524, doi. 10.1002/ange.201606091

By:

Lam, Hiu C.;
Spence, Justin T. J.;
George, Jonathan H.

Publication type:

Article

Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.

Published in:

Angewandte Chemie, 2016, v. 128, n. 21, p. 6315, doi. 10.1002/ange.201600940

By:

Yamamoto, Tsuyoshi;
Tsunematsu, Yuta;
Hara, Kodai;
Suzuki, Tomohiro;
Kishimoto, Shinji;
Kawagishi, Hirokazu;
Noguchi, Hiroshi;
Hashimoto, Hiroshi;
Tang, Yi;
Hotta, Kinya;
Watanabe, Kenji

Publication type:

Article

Stereodivergent and Protecting-Group-Free Synthesis of the Helicascolide Family: A Rhodium-Catalyzed Atom-Economical Lactonization Strategy.

Published in:

Angewandte Chemie, 2016, v. 128, n. 19, p. 5859, doi. 10.1002/ange.201600632

By:

Haydl, Alexander M.;
Berthold, Dino;
Spreider, Pierre A.;
Breit, Bernhard

Publication type:

Article

Total Synthesis of Cryptocaryol A by Enantioselective Iridium-Catalyzed Alcohol C−H Allylation.

Published in:

Angewandte Chemie, 2016, v. 128, n. 16, p. 5133, doi. 10.1002/ange.201600591

By:

Perez, Felix;
Waldeck, Andrew R.;
Krische, Michael J.

Publication type:

Article

Ruthenium(0)-Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α-Ketols: Convergent Construction of Angucycline Ring Systems.

Published in:

Angewandte Chemie, 2016, v. 128, n. 4, p. 1515, doi. 10.1002/ange.201509646

By:

Saxena, Aakarsh;
Perez, Felix;
Krische, Michael J.

Publication type:

Article

Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals.

Published in:

Angewandte Chemie, 2016, v. 128, n. 1, p. 240, doi. 10.1002/ange.201509342

By:

Farrell, Mark;
Melillo, Bruno;
Smith, Amos B.

Publication type:

Article

Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis.

Published in:

Angewandte Chemie, 2015, v. 127, n. 46, p. 13826, doi. 10.1002/ange.201507090

By:

Luhavaya, Hanna;
Dias, Marcio V. B.;
Williams, Simon R.;
Hong, Hui;
de Oliveira, Luciana G.;
Leadlay, Peter F.

Publication type:

Article

Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis.

Published in:

Angewandte Chemie, 2015, v. 127, n. 45, p. 13664, doi. 10.1002/ange.201506899

By:

Zhang, Lihan;
Mori, Takahiro;
Zheng, Qingfei;
Awakawa, Takayoshi;
Yan, Yan;
Liu, Wen;
Abe, Ikuro

Publication type:

Article

Discovery, Structure Elucidation, and Biological Characterization of Nannocystin A, a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties.

Published in:

Angewandte Chemie, 2015, v. 127, n. 35, p. 10283, doi. 10.1002/ange.201411377

By:

Hoffmann, Holger;
Kogler, Herbert;
Heyse, Winfried;
Matter, Hans;
Caspers, Michael;
Schummer, Dietmar;
Klemke ‐ Jahn, Christine;
Bauer, Armin;
Penarier, Geraldine;
Debussche, Laurent;
Brönstrup, Mark

Publication type:

Article

Toward Naphthocyclinones: Doubly Connected Octaketide Dimers with a Bicyclo[3.2.1]octadienone Core by Thiolate-Mediated Cyclization.

Published in:

Angewandte Chemie, 2015, v. 127, n. 33, p. 9786, doi. 10.1002/ange.201503442

By:

Ando, Yoshio;
Hori, Subaru;
Fukazawa, Takumi;
Ohmori, Ken;
Suzuki, Keisuke

Publication type:

Article

Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional syn-1,3-Diol Derivatives.

Published in:

Angewandte Chemie, 2015, v. 127, n. 27, p. 7968, doi. 10.1002/ange.201501995

By:

Holt, Dean;
Gaunt, Matthew J.

Publication type:

Article

Selective Formation of a Trisubstituted Alkene Motif by trans-Hydrostannation/Stille Coupling: Application to the Total Synthesis and Late-Stage Modification of 5,6-Dihydrocineromycin B.

Published in:

Angewandte Chemie, 2015, v. 127, n. 21, p. 6339, doi. 10.1002/ange.201501608

By:

Rummelt, Stephan M.;
Preindl, Johannes;
Sommer, Heiko;
Fürstner, Alois

Publication type:

Article

Total Synthesis of (±)-Hippolachnin A.

Published in:

Angewandte Chemie, 2015, v. 127, n. 8, p. 2408, doi. 10.1002/ange.201410419

By:

Ruider, Stefan A.;
Sandmeier, Tobias;
Carreira, Erick M.

Publication type:

Article

Divergent Mechanistic Routes for the Formation of gem-Dimethyl Groups in the Biosynthesis of Complex Polyketides.

Published in:

Angewandte Chemie, 2015, v. 127, n. 8, p. 2400, doi. 10.1002/ange.201410124

By:

Poust, Sean;
Phelan, Ryan M.;
Deng, Kai;
Katz, Leonard;
Petzold, Christopher J.;
Keasling, Jay D.

Publication type:

Article

Chemoenzymatic Synthesis of Spinosyn A.

Published in:

Angewandte Chemie, 2014, v. 126, n. 49, p. 13771, doi. 10.1002/ange.201407806

By:

Kim, Hak Joong;
Choi, Sei ‐ hyun;
Jeon, Byung ‐ sun;
Kim, Namho;
Pongdee, Rongson;
Wu, Qingquan;
Liu, Hung ‐ wen

Publication type:

Article

Chemical Probes for the Functionalization of Polyketide Intermediates.

Published in:

Angewandte Chemie, 2014, v. 126, n. 44, p. 12138, doi. 10.1002/ange.201407448

By:

Riva, Elena;
Wilkening, Ina;
Gazzola, Silvia;
Li, W. M. Ariel;
Smith, Luke;
Leadlay, Peter F.;
Tosin, Manuela

Publication type:

Article

Synthesis of Polyketide Stereoarrays Enabled by a Traceless Oxonia-Cope Rearrangement.

Published in:

Angewandte Chemie, 2014, v. 126, n. 43, p. 11784, doi. 10.1002/ange.201407231

By:

Yang, Lin;
He, Guoli;
Yin, Ruifeng;
Zhu, Lili;
Wang, Xiaoxia;
Hong, Ran

Publication type:

Article

Forazoline A: Marine-Derived Polyketide with Antifungal In Vivo Efficacy.

Published in:

Angewandte Chemie, 2014, v. 126, n. 43, p. 11767, doi. 10.1002/ange.201405990

By:

Wyche, Thomas P.;
Piotrowski, Jeff S.;
Hou, Yanpeng;
Braun, Doug;
Deshpande, Raamesh;
McIlwain, Sean;
Ong, Irene M.;
Myers, Chad L.;
Guzei, Ilia A.;
Westler, William M.;
Andes, David R.;
Bugni, Tim S.

Publication type:

Article

Total Synthesis of Myceliothermophins C, D, and E.

Published in:

Angewandte Chemie, 2014, v. 126, n. 41, p. 11150, doi. 10.1002/ange.201406815

By:

Nicolaou, K. C.;
Shi, Lei;
Lu, Min;
Pattanayak, Manas R.;
Shah, Akshay A.;
Ioannidou, Heraklidia A.;
Lamani, Manjunath

Publication type:

Article

Elucidation of Pseurotin Biosynthetic Pathway Points to Trans-Acting C-Methyltransferase: Generation of Chemical Diversity.

Published in:

Angewandte Chemie, 2014, v. 126, n. 32, p. 8615, doi. 10.1002/ange.201404804

By:

Tsunematsu, Yuta;
Fukutomi, Manami;
Saruwatari, Takayoshi;
Noguchi, Hiroshi;
Hotta, Kinya;
Tang, Yi;
Watanabe, Kenji

Publication type:

Article

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium.

Published in:

Angewandte Chemie, 2014, v. 126, n. 30, p. 7990, doi. 10.1002/ange.201402632

By:

Pidot, Sacha;
Ishida, Keishi;
Cyrulies, Michael;
Hertweck, Christian

Publication type:

Article

Iterative Assembly of Two Separate Polyketide Chains by the Same Single-Module Bacterial Polyketide Synthase in the Biosynthesis of HSAF.

Published in:

Angewandte Chemie, 2014, v. 126, n. 29, p. 7654, doi. 10.1002/ange.201403500

By:

Li, Yaoyao;
Chen, Haotong;
Ding, Yanjiao;
Xie, Yunxuan;
Wang, Haoxin;
Cerny, Ronald L.;
Shen, Yuemao;
Du, Liangcheng

Publication type:

Article

Biosynthesis of the Structurally Unique Polycyclopropanated Polyketide-Nucleoside Hybrid Jawsamycin (FR-900848).

Published in:

Angewandte Chemie, 2014, v. 126, n. 21, p. 5527, doi. 10.1002/ange.201402623

By:

Hiratsuka, Tomoshige;
Suzuki, Hideaki;
Kariya, Ryo;
Seo, Takashi;
Minami, Atsushi;
Oikawa, Hideaki

Publication type:

Article

Total Synthesis of Syringolin A and Improvement of Its Biological Activity.

Published in:

Angewandte Chemie, 2014, v. 126, n. 19, p. 4936, doi. 10.1002/ange.201402428

By:

Chiba, Takuya;
Hosono, Hidetaka;
Nakagawa, Koji;
Asaka, Masahiro;
Takeda, Hiroshi;
Matsuda, Akira;
Ichikawa, Satoshi

Publication type:

Article

Accelerating Spirocyclic Polyketide Synthesis using Flow Chemistry.

Published in:

Angewandte Chemie, 2014, v. 126, n. 19, p. 5015, doi. 10.1002/ange.201402056

By:

Newton, Sean;
Carter, Catherine F.;
Pearson, Colin M.;
de C. Alves, Leandro;
Lange, Heiko;
Thansandote, Praew;
Ley, Steven V.

Publication type:

Article

Stereocontrol of All-Carbon Quaternary Centers through Enantioselective Desymmetrization of Meso Primary Diols by Organocatalyzed Acyl Transfer.

Published in:

Angewandte Chemie, 2014, v. 126, n. 3, p. 785, doi. 10.1002/ange.201308268

By:

Roux, Christèle;
Candy, Mathieu;
Pons, Jean ‐ Marc;
Chuzel, Olivier;
Bressy, Cyril

Publication type:

Article

Divergent Total Synthesis of Indoxamycins A, C, and F.

Published in:

Angewandte Chemie, 2013, v. 125, n. 50, p. 13498, doi. 10.1002/ange.201307426

By:

He, Chi;
Zhu, Chenlong;
Dai, Zhifeng;
Tseng, Chih ‐ Chung;
Ding, Hanfeng

Publication type:

Article

A Common Origin for Guanidinobutanoate Starter Units in Antifungal Natural Products.

Published in:

Angewandte Chemie, 2013, v. 125, n. 49, p. 13334, doi. 10.1002/ange.201308136

By:

Hong, Hui;
Fill, Taicia;
Leadlay, Peter F.

Publication type:

Article

Structure-Based Gene Targeting Discovery of Sphaerimicin, a Bacterial Translocase I Inhibitor.

Published in:

Angewandte Chemie, 2013, v. 125, n. 44, p. 11821, doi. 10.1002/ange.201305546

By:

Funabashi, Masanori;
Baba, Satoshi;
Takatsu, Toshio;
Kizuka, Masaaki;
Ohata, Yasuo;
Tanaka, Masahiro;
Nonaka, Koichi;
Spork, Anatol P.;
Ducho, Christian;
Chen, Wei ‐ Chen Leyla;
Van Lanen, Steven G.

Publication type:

Article

Total Synthesis of (−)-Rhizopodin.

Published in:

Angewandte Chemie, 2013, v. 125, n. 25, p. 6645, doi. 10.1002/ange.201301978

By:

Dalby, Stephen M.;
Goodwin-Tindall, Jake;
Paterson, Ian

Publication type:

Article

Phytotoxic polyketides produced by Phomopsis foeniculi, a strain isolated from diseased Bulgarian fennel.

Published in:

European Journal of Plant Pathology, 2011, v. 130, n. 2, p. 173, doi. 10.1007/s10658-011-9743-0

By:

Evidente, Antonio;
Rodeva, Rossitza;
Andolfi, Anna;
Stoyanova, Zornitsa;
Perrone, Carmen;
Motta, Andrea

Publication type:

Article

Advances of antitumor drug discovery in traditional Chinese medicine and natural active products by using multi‐active components combination.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 5, p. 1778, doi. 10.1002/med.21963

By:

Zhao, Wei;
Zheng, Xiao‐Di;
Tang, Paula Yun‐Zhi;
Li, Hong‐Mei;
Liu, Xue;
Zhong, Jian‐Jiang;
Tang, Ya‐Jie

Publication type:

Article

Comparative Analyses of Scylla olivacea Gut Microbiota Composition and Function Suggest the Capacity for Polyunsaturated Fatty Acid Biosynthesis.

Published in:

Microbial Ecology, 2023, v. 86, n. 1, p. 575, doi. 10.1007/s00248-022-02046-0

By:

Lau, Nyok-Sean;
Ting, Seng Yeat;
Sam, Ka-Kei;
M., Janaranjani;
Wong, Swe Cheng;
Wu, Xugan;
Waiho, Khor;
Fazhan, Hanafiah;
Shu-Chien, Alexander Chong

Publication type:

Article