We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cochleovestibular nerve involvement in multifocal fibrosclerosis.
- Authors
Tsuji, R K; Bittencourt, A G; Arai, M H; Santiago Gebrim, E M
- Abstract
Objectives:To report a case of multifocal fibrosclerosis with a nine-year follow up, and to discuss this disease's radiological appearance and management. The disease is a rare systemic disorder of unknown cause characterised by fibrous proliferation involving multiple anatomical sites.Case report:A 50-year-old woman presented with histological findings characterised by similar inflammatory processes involving the meninges, pituitary gland, peritoneum, retroperitoneum and orbits, prompting a search for a common pathophysiology. A diagnosis of multifocal fibrosclerosis was postulated. Symptom improvement was noted after treatment with prednisone and azathioprine.Conclusion:This is the first documented case of involvement of the cochleovestibular nerve in a patient with multifocal fibrosclerosis. The rare association between fibrotic diseases and masses showing various clinical patterns should be kept in mind by otolaryngologists, and imaging performed to investigate for multifocal fibrosclerosis. However, diagnosis can only be confirmed with tissue biopsy and histopathological examination.
- Subjects
PREDNISONE; AZATHIOPRINE; ACOUSTIC nerve; BIOPSY; DEAFNESS; MAGNETIC resonance imaging; TINNITUS; TOMOGRAPHY; VERTIGO; FIBROSIS; DIAGNOSIS; THERAPEUTICS
- Publication
Journal of Laryngology & Otology, 2012, Vol 126, Issue 9, p935
- ISSN
0022-2151
- Publication type
Academic Journal
- DOI
10.1017/S0022215112001387