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Title: Poster 82 Intronic Single Nucleotide Polymorphism of the CALM‐1 Gene Is Significantly Associated With Knee Osteoarthritis: A Case Control Study.
Authors: Sanghi, Divya; Avasthi, Sachin; Ganesh, S.; Srivastava, Rajeshwar N.
Abstract: The Japanese population has shown a higher incidence of osteoarthritis in patients with intronic and core promoter single nucleotide polymorphism (SNP) in the CALM-1 gene. Among SNP positive cases and controls, 5 cases (8.7%) and no controls were heterozygosis for the occurrence of SNP. Genetic polymorphism in relation to the intronic region of the Calm-1 gene was studied by DNA extraction, polymerase chain reaction and restriction fragment length polymorphism method.
Subjects: SINGLE nucleotide polymorphisms; KNEE osteoarthritis; GENETIC polymorphisms; OSTEOARTHRITIS; KNEE pain; RESTRICTION fragment length polymorphisms
Publication: PM & R: Journal of Injury, Function & Rehabilitation, 2011, Vol 3, pS168
ISSN: 1934-1482
Publication type: Academic Journal
DOI: 10.1016/j.pmrj.2011.08.036

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Poster 82 Intronic Single Nucleotide Polymorphism of the CALM‐1 Gene Is Significantly Associated With Knee Osteoarthritis: A Case Control Study.