Development of two reference materials for all trans-retinol, retinyl palmitate, α- and γ-tocopherol in milk powder and infant formula.

Shehata, Adel B.; Rizk, Mahmoud S.; Farag, Ahmad M.; Tahoun, Ibrahim F.

Vitamins are important food constituents that can be present in almost every foodstuff. Food quality and safety depends on food surveillance by reliable quantitative analysis enabled by appropriate quality control. Certified matrix reference materials are versatile tools to support quality assurance and control. However, in the case of vitamins, which are important in various foods, there is a lack of matrix reference materials. Two certified reference materials for the determination of all-trans-retinol, retinyl palmitate, and α- and γ-tocopherol in milk powder and infant formula have been developed by the National Institute of Standards, Egypt. This article presents the preparation, characterization, homogeneity, and stability testing as well as statistical treatment of data and certified value assignment. The assignment of the certified values and associated uncertainties in the prepared natural-matrix reference materials were based on the widely used approach of combining data from independent and reliable analytical methods.

EGYPT; FATTY acid analysis; MILK analysis; VITAMIN E analysis; ANALYSIS of variance; CALIBRATION; CONFIDENCE intervals; FOOD chemistry; HIGH performance liquid chromatography; INFANT formulas; QUALITY control; REGRESSION analysis; SPECTROPHOTOMETRY; VITAMIN A; FOOD safety; REPEATED measures design; DATA analysis software; DESCRIPTIVE statistics

Journal of Food & Drug Analysis, 2015, Vol 23, Issue 1, p82

1021-9498

Academic Journal

10.1016/j.jfda.2014.10.004