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Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers.
- Published in:
- 2016
- By:
- Publication type:
- journal article
P3‐072: QUANTITATIVE MEASUREMENT OF AMYLOID BETA OLIGOMER IN MOUSE BRAIN USING DOT BLOT ASSAY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P953, doi. 10.1016/j.jalz.2019.06.3099
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- Publication type:
- Article
P2‐054: MOLECULAR IMAGING AND TREATMENT OF ALZHEIMER'S DISEASE BY DEVELOPING AMYLOID‐β OLIGOMER ANTIBODIES THAT CROSS THE BLOOD‐BRAIN BARRIER.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P687, doi. 10.1016/j.jalz.2018.06.739
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- Publication type:
- Article
Nasal Rifampicin Improves Cognition in a Mouse Model of Dementia with Lewy Bodies by Reducing α-Synuclein Oligomers.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8453, doi. 10.3390/ijms22168453
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- Publication type:
- Article
Heavy Tau Burden with Subtle Amyloid β Accumulation in the Cerebral Cortex and Cerebellum in a Case of Familial Alzheimer's Disease with APP Osaka Mutation.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4443, doi. 10.3390/ijms21124443
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- Publication type:
- Article
APP Osaka Mutation in Familial Alzheimer's Disease—Its Discovery, Phenotypes, and Mechanism of Recessive Inheritance.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1413, doi. 10.3390/ijms21041413
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- Publication type:
- Article
Intraneuronal amyloid-beta oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Regulation of cholesterol efflux by amyloid β secretion
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Hypercholesterolemia accelerates memory impairment in a transgenic mouse model of Abeta oligomers
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Intraneuronal accumulation of Aβ oligomers causes abnormal tau phosphorylation, glial activation and neuronal loss in transgenic mice with APP E693Δ mutation
- Published in:
- 2010
- By:
- Publication type:
- Abstract
A transgenic mouse model of amyloid β oligomers: Pathological effects of the E693Δ mutation in amyloid precursor protein in vivo
- Published in:
- 2009
- By:
- Publication type:
- Abstract
P4-258: Amyloid imaging of a patient with Alzheimer's disease harboring a novel APP mutation (E693Δ)
- Published in:
- 2008
- By:
- Publication type:
- Abstract
O4-06-08: Identification and characterization of a novel APP mutation (E693Δ) in familial Alzheimer's disease
- Published in:
- 2008
- By:
- Publication type:
- Abstract
The domestic cat as a natural animal model of Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, p. 1, doi. 10.1186/s40478-015-0258-3
- By:
- Publication type:
- Article
Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0230-2
- By:
- Publication type:
- Article
E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.
- Published in:
- 2011
- By:
- Publication type:
- Journal Article
E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.
- Published in:
- International Journal of Alzheimer's Disease, 2011, v. 2011, p. 1, doi. 10.4061/2011/431320
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- Publication type:
- Article
The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.
- Published in:
- Journal of Neuroscience Research, 2013, v. 91, n. 12, p. 1541, doi. 10.1002/jnr.23278
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- Publication type:
- Article
Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.
- Published in:
- Journal of Neuroscience Research, 2011, v. 89, n. 7, p. 1031, doi. 10.1002/jnr.22640
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- Publication type:
- Article
Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease.
- Published in:
- Dementia & Geriatric Cognitive Disorders, 2018, v. 8, n. 1, p. 77, doi. 10.1159/000487358
- By:
- Publication type:
- Article
Clinical Course of Patients with Familial Early-Onset Alzheimer's Disease Potentially Lacking Senile Plaques Bearing the E693Δ Mutation in Amyloid Precursor Protein.
- Published in:
- 2011
- By:
- Publication type:
- Journal Article
Clinical Course of Patients with Familial Early-Onset Alzheimer's Disease Potentially Lacking Senile Plaques Bearing the E693Δ Mutation in Amyloid Precursor Protein.
- Published in:
- Dementia & Geriatric Cognitive Disorders, 2011, v. 32, n. 1, p. 45, doi. 10.1159/000330017
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- Publication type:
- Article
Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice.
- Published in:
- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0461-5
- By:
- Publication type:
- Article
Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A<sub>2</sub> in a spatial-specific manner.
- Published in:
- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0460-6
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- Publication type:
- Article
A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 14, p. 4845, doi. 10.1523/JNEUROSCI.5825-09.2010
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- Publication type:
- Article
Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography.
- Published in:
- Journal of Neuroscience, 2007, v. 27, n. 41, p. 10957, doi. 10.1523/JNEUROSCI.0673-07.2007
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- Publication type:
- Article
Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy.
- Published in:
- Journal of Neuroscience, 2006, v. 26, n. 13, p. 3514, doi. 10.1523/JNEUROSCI.5425-05.2006
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- Publication type:
- Article
Hawaiian native herb Mamaki prevents dementia by ameliorating neuropathology and repairing neurons in four different mouse models of neurodegenerative diseases.
- Published in:
- GeroScience, 2024, v. 46, n. 2, p. 1971, doi. 10.1007/s11357-023-00950-y
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- Publication type:
- Article
Lack of amyloid plaque formation in the central nervous system of a patient with Werner syndrome.
- Published in:
- Neuropathology, 2003, v. 23, n. 1, p. 51, doi. 10.1046/j.1440-1789.2003.00474.x
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- Publication type:
- Article
The Syntaxin 5 Isoforms Syx5 and Syx5L have Distinct Effects on the Processing of β-amyloid Precursor Protein.
- Published in:
- Journal of Biochemistry, 2009, v. 146, n. 6, p. 905, doi. 10.1093/jb/mvp138
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- Publication type:
- Article
A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia.
- Published in:
- Annals of Neurology, 2008, v. 63, n. 3, p. 377, doi. 10.1002/ana.21321
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- Publication type:
- Article
Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice.
- Published in:
- FASEB Journal, 2007, v. 21, n. 9, p. 2149, doi. 10.1096/fj.06-7735com
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- Publication type:
- Article
Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice.
- Published in:
- Acta Neuropathologica, 2014, v. 127, n. 5, p. 685, doi. 10.1007/s00401-014-1259-1
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- Publication type:
- Article
Intranasal rifampicin for Alzheimer's disease prevention.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2018, v. 4, n. 1, p. 304, doi. 10.1016/j.trci.2018.06.012
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- Publication type:
- Article
C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice.
- Published in:
- Biomedicines, 2022, v. 10, n. 5, p. 1080, doi. 10.3390/biomedicines10051080
- By:
- Publication type:
- Article
Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice.
- Published in:
- Biomedicines, 2022, v. 10, n. 2, p. 297, doi. 10.3390/biomedicines10020297
- By:
- Publication type:
- Article
Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease.
- Published in:
- Dementia & Geriatric Cognitive Disorders Extra, 2018, v. 8, n. 1, p. 77, doi. 10.1159/000487358
- By:
- Publication type:
- Article
Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain.
- Published in:
- Journal of Neuroscience, 2019, v. 39, n. 34, p. 6781, doi. 10.1523/JNEUROSCI.2845-18.2019
- By:
- Publication type:
- Article
Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain.
- Published in:
- Journal of Nanobiotechnology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12951-023-01772-y
- By:
- Publication type:
- Article
Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid β Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer's Disease.
- Published in:
- Molecules, 2021, v. 26, n. 5, p. 1362, doi. 10.3390/molecules26051362
- By:
- Publication type:
- Article
Regulation of tau exon 10 splicing by a double stem–loop structure in mouse intron 10
- Published in:
- FEBS Letters, 2005, v. 579, n. 1, p. 241, doi. 10.1016/j.febslet.2004.11.090
- By:
- Publication type:
- Article
Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of βAPP in neuronal cells.
- Published in:
- Journal of Neurochemistry, 2005, v. 94, n. 2, p. 425, doi. 10.1111/j.1471-4159.2005.03210.x
- By:
- Publication type:
- Article
Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice.
- Published in:
- Annals of Clinical & Translational Neurology, 2015, v. 2, n. 3, p. 241, doi. 10.1002/acn3.171
- By:
- Publication type:
- Article
Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease.
- Published in:
- Neuropathology, 2017, v. 37, n. 6, p. 495, doi. 10.1111/neup.12395
- By:
- Publication type:
- Article
New Value of Acorus tatarinowii / gramineus Leaves as a Dietary Source for Dementia Prevention.
- Published in:
- Nutrients, 2024, v. 16, n. 11, p. 1589, doi. 10.3390/nu16111589
- By:
- Publication type:
- Article
Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer’s disease.
- Published in:
- PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0174630
- By:
- Publication type:
- Article
Oligomer-Targeting Prevention of Neurodegenerative Dementia by Intranasal Rifampicin and Resveratrol Combination – A Preclinical Study in Model Mice.
- Published in:
- Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.763476
- By:
- Publication type:
- Article
In Vivo Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 12, p. 4720, doi. 10.1523/JNEUROSCI.3076-10.2011
- By:
- Publication type:
- Article