Found: 45
Select item for more details and to access through your institution.
Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity.
- Published in:
- 2016
- By:
- Publication type:
- journal article
In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 26, p. 8844, doi. 10.1523/JNEUROSCI.23-26-08844.2003
- By:
- Publication type:
- Article
Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 21, p. 7889, doi. 10.1523/JNEUROSCI.23-21-07889.2003
- By:
- Publication type:
- Article
Efficacy evaluation of a novel vectorized anti‐tau antibody, targeting a C‐terminal phospho‐tau epitope, using systemic dosing of a blood brain barrier penetrant AAV capsid in mouse models of tauopathies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062924
- By:
- Publication type:
- Article
Identification and characterization of novel anti‐tau antibodies that inhibit tau‐seed mediated pathology in a P301S tauopathy mouse model Alzheimer's Disease and tauopathies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.062878
- By:
- Publication type:
- Article
Efficacy of a vectorized anti‐tau antibody using systemic dosing of a blood brain barrier penetrant AAV capsid in mouse models of tauopathies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.053341
- By:
- Publication type:
- Article
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-Aβ antibody.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 3, p. 825, doi. 10.1172/JCI27120
- By:
- Publication type:
- Article
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-ß peptides.
- Published in:
- Nature Medicine, 2004, v. 10, n. 7, p. 719, doi. 10.1038/nm1058
- By:
- Publication type:
- Article
INHIBITION OF BACE2 AFFECTS MELANOSOME ULTRASTRUCTURE AND CAUSES OF HYPOPIGMENTATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P442, doi. 10.1016/j.jalz.2016.06.854
- By:
- Publication type:
- Article
Novel fluid biomarkers for brain amyloid and dementia risk in presymptomatic Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P255, doi. 10.1016/j.jalz.2015.07.317
- By:
- Publication type:
- Article
A potential endophenotype for Alzheimer’s disease: Cerebrospinal fluid clusterin.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P280, doi. 10.1016/j.jalz.2015.07.374
- By:
- Publication type:
- Article
Evaluating amyloid-beta processing using novel gamma-secretase modulators in preclinical animal models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P905, doi. 10.1016/j.jalz.2015.08.145
- By:
- Publication type:
- Article
The effect of 5-lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer-like pathology
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Pharmacokinetic/pharmacodynamic analysis of β-amyloid response following modulation of the gamma secretase enzyme
- Published in:
- 2010
- By:
- Publication type:
- Abstract
IP/MS analysis of human CSF Aβ following a single dose of the C-terminal anti-Aβ antibody ponezumab (PF-04360365) to Alzheimer patients
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Transgene dependent, doxycycline-sensitive cognitive deficits in Tg4510 mutant mouse correlate with insoluble tau epitope accumulation
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Modeling the genetic effect of apoE in Alzheimer's disease using expression profile analysis of apoE-targeted replacement mice
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P4-322: Complete environmental enrichment is required to protect AD transgenic mice against cognitive impairment, reduce a-beta deposition, and increase synaptophysin staining: Involvement of both amyloid-dependent and independent mechanisms
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-272: Association of a functional variant (I89V) in the high affinity choline transporter with Alzheimer’s disease
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-007: Alterations in metabotropic and ionotropic glutamate receptor expression in the APP <sup>V717F</sup> transgenic mouse model of Alzheimer’s disease
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-003: Thiorphan infusion induces deposition of beta-amyloid in PDAPP transgenic mice
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P4-322: Complete environmental enrichment is required to protect AD transgenic mice against cognitive impairment, reduce a-beta deposition, and increase synaptophysin staining: Involvement of both amyloid-dependent and independent mechanisms
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-272: Association of a functional variant (I89V) in the high affinity choline transporter with Alzheimer’s disease
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-007: Alterations in metabotropic and ionotropic glutamate receptor expression in the APP <sup>V717F</sup> transgenic mouse model of Alzheimer’s disease
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-003: Thiorphan infusion induces deposition of beta-amyloid in PDAPP transgenic mice
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis.
- Published in:
- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018850
- By:
- Publication type:
- Article
Human APOE Isoform-Dependent Effects on Brain β-Amyloid Levels in PDAPP Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 21, p. 6771, doi. 10.1523/JNEUROSCI.0887-09.2009
- By:
- Publication type:
- Article
Macrophage-Mediated Degradation of β-Amyloid via an Apolipoprotein E Isoform-Dependent Mechanism.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 11, p. 3603, doi. 10.1523/JNEUROSCI.5302-08.2009
- By:
- Publication type:
- Article
Treatment with an Amyloid-β Antibody Ameliorates Plaque Load, Learning Deficits, and Hippocampal Long-Term Potentiation in a Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 26, p. 6213, doi. 10.1523/JNEUROSCI.0664-05.2005
- By:
- Publication type:
- Article
Human Apolipoprotein E4 Alters the Amyloid-β 40:42 Ratio and Promotes the Formation of Cerebral Amyloid Angiopathy in an Amyloid Precursor Protein Transgenic Model.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 11, p. 2803, doi. 10.1523/JNEUROSCI.5170-04.2005
- By:
- Publication type:
- Article
Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposited Forms of Amyloid β.
- Published in:
- Journal of Neuroscience, 2005, v. 25, n. 3, p. 629, doi. 10.1523/JNEUROSCI.4337-04.2005
- By:
- Publication type:
- Article
Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid β-peptide deposition in homozygous APP<sup>V717F</sup> transgenic mice.
- Published in:
- Acta Neuropathologica, 2000, v. 100, n. 5, p. 451, doi. 10.1007/s004010000263
- By:
- Publication type:
- Article
Translocator protein in late stage Alzheimer's disease and Dementia with Lewy bodies brains.
- Published in:
- Annals of Clinical & Translational Neurology, 2019, v. 6, n. 8, p. 1423, doi. 10.1002/acn3.50837
- By:
- Publication type:
- Article
Human apoE Isoforms Differentially Regulate Brain Amyloid-b Peptide Clearance.
- Published in:
- Science Translational Medicine, 2011, v. 3, n. 89, p. 1, doi. 10.1126/scitranslmed.3002156
- By:
- Publication type:
- Article
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model.
- Published in:
- Nature Neuroscience, 2002, v. 5, n. 5, p. 452, doi. 10.1038/nn842
- By:
- Publication type:
- Article
Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat.
- Published in:
- European Journal of Neuroscience, 2005, v. 22, n. 1, p. 21, doi. 10.1111/j.1460-9568.2005.04182.x
- By:
- Publication type:
- Article
Sodium Salicylate and 17β-Estradiol Attenuate Nuclear Transcription Factor NF-κB Translocation in Cultured Rat Astroglial Cultures Following Exposure to Amyloid Aβ<sub>1-40</sub> and Lipoplysaccharides.
- Published in:
- Journal of Neurochemistry, 1999, v. 73, n. 4, p. 1453, doi. 10.1046/j.1471-4159.1999.0731453.x
- By:
- Publication type:
- Article
α<sub>2</sub>-Macroglobulin Attenuates β-Amyloid Peptide 1-40 Fibril Formation and Associated Neurotoxicity of Cultured Fetal Rat Cortical Neurons.
- Published in:
- Journal of Neurochemistry, 1998, v. 70, n. 3, p. 1182, doi. 10.1046/j.1471-4159.1998.70031182.x
- By:
- Publication type:
- Article
Involvement of a Caspase-3-Like Cysteine Protease in 1-Methyl-4-Phenylpyridinium-Mediated Apoptosis of Cultured Cerebellar Granule Neurons.
- Published in:
- Journal of Neurochemistry, 1997, v. 69, n. 4, p. 1382, doi. 10.1046/j.1471-4159.1997.69041382.x
- By:
- Publication type:
- Article
α<sub>2</sub>-Macroglobulin as a β-Amyloid Peptide-Binding Plasma Protein.
- Published in:
- Journal of Neurochemistry, 1997, v. 69, n. 1, p. 299, doi. 10.1046/j.1471-4159.1997.69010299.x
- By:
- Publication type:
- Article
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion.
- Published in:
- PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194661
- By:
- Publication type:
- Article