Works matching Anthrax toxin

Results: 594

Recombinant HSA-CMG2 Is a Promising Anthrax Toxin Inhibitor.

Published in:

Toxins, 2016, v. 8, n. 1, p. 28, doi. 10.3390/toxins8010028

By:

Liangliang Li;
Qiang Guo;
Ju Liu;
Jun Zhang;
Ying Yin;
Dayong Dong;
Ling Fu;
Junjie Xu;
Wei Chen

Publication type:

Article

Design of Monodisperse and Well-Defined Polypeptide-Based Polyvalent Inhibitors of Anthrax Toxin.

Published in:

Angewandte Chemie, 2014, v. 126, n. 31, p. 8175, doi. 10.1002/ange.201400870

By:

Patke, Sanket;
Boggara, Mohan;
Maheshwari, Ronak;
Srivastava, Sunit K.;
Arha, Manish;
Douaisi, Marc;
Martin, Jacob T.;
Harvey, Ian B.;
Brier, Matthew;
Rosen, Tania;
Mogridge, Jeremy;
Kane, Ravi S.

Publication type:

Article

Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain.

Published in:

Toxins, 2017, v. 9, n. 10, p. 298, doi. 10.3390/toxins9100298

By:

Machen, Alexandra J.;
Akkaladevi, Narahari;
Trecazzi, Caleb;
O'Neil, Pierce T.;
Mukherjee, Srayanta;
Qi, Yifei;
Dillard, Rebecca;
Wonpil Im;
Gogol, Edward P.;
White, Tommi A.;
Fisher, Mark T.

Publication type:

Article

Studies in Mice Reveal a Role for Anthrax Toxin Receptors in Matrix Metalloproteinase Function and Extracellular Matrix Homeostasis.

Published in:

Toxins, 2013, v. 5, n. 2, p. 315, doi. 10.3390/toxins5020315

By:

Reeves, Claire;
Charles-Horvath, Pelisa;
Kitajewski, Jan

Publication type:

Article

Exposure to anthrax toxin alters human leucocyte expression of anthrax toxin receptor 1.

Published in:

Clinical & Experimental Immunology, 2013, v. 173, n. 1, p. 84, doi. 10.1111/cei.12090

By:

Ingram, R. J.;
Harris, A.;
Ascough, S.;
Metan, G.;
Doganay, M.;
Ballie, L.;
Williamson, E. D.;
Dyson, H.;
Robinson, J. H.;
Sriskandan, S.;
Altmann, D. M.

Publication type:

Article

Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation.

Published in:

Toxins, 2016, v. 8, n. 2, p. 34, doi. 10.3390/toxins8020034

By:

Sun, Jianjun;
Jacquez, Pedro

Publication type:

Article

Phage Display Analysis of Monoclonal Antibody Binding to Anthrax Toxin Lethal Factor.

Published in:

Toxins, 2017, v. 9, n. 7, p. 221, doi. 10.3390/toxins9070221

By:

Goldstein, Jason M.;
Joo Lee;
Xiaoling Tang;
Boyer, Anne E.;
Barr, John R.;
Bagarozzi Jr., Dennis A.;
Quinn, Conrad P.

Publication type:

Article

Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study.

Published in:

Toxins, 2016, v. 8, n. 11, p. 337, doi. 10.3390/toxins8110337

By:

Yamini, Goli;
Kalu, Nnanya;
Nestorovich, Ekaterina M.

Publication type:

Article

Tumor Targeting and Drug Delivery by Anthrax Toxin.

Published in:

Toxins, 2016, v. 8, n. 7, p. 197, doi. 10.3390/toxins8070197

By:

Bachran, Christopher;
Leppla, Stephen H.

Publication type:

Article

The Receptors that Mediate the Direct Lethality of Anthrax Toxin.

Published in:

Toxins, 2013, v. 5, n. 1, p. 1, doi. 10.3390/toxins5010001

By:

Shihui Liu;
Yi Zhang;
Hoover, Benjamin;
Leppla, Stephen H.

Publication type:

Article

Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146586

By:

Andersen, N. J.;
Boguslawski, E. A.;
Naidu, A. S.;
Szot, C.;
Bromberg-White, J. L.;
Kits, K.;
Kuk, C. Y.;
Holton, L. E.;
St. Croix, B.;
Chambers, C. M.;
Duesbery, N. S.

Publication type:

Article

The Disulfide Bond Cys255-Cys279 in the Immunoglobulin-Like Domain of Anthrax Toxin Receptor 2 Is Required for Membrane Insertion of Anthrax Protective Antigen Pore.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130832

By:

Jacquez, Pedro;
Avila, Gustavo;
Boone, Kyle;
Altiyev, Agamyrat;
Puschhof, Jens;
Sauter, Roland;
Arigi, Emma;
Ruiz, Blanca;
Peng, Xiuli;
Almeida, Igor;
Sherman, Michael;
Xiao, Chuan;
Sun, Jianjun

Publication type:

Article

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066099

By:

Beitzinger, Christoph;
Bronnhuber, Anika;
Duscha, Kerstin;
Riedl, Zsuzsanna;
Huber-Lang, Markus;
Benz, Roland;
Hajós, György;
Barth, Holger

Publication type:

Article

Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034611

By:

Thomas, Diane;
Naughton, John;
Cote, Christopher;
Welkos, Susan;
Manchester, Marianne;
Young, John A. T.

Publication type:

Article

Tumor Endothelium Marker-8 Based Decoys Exhibit Superiority over Capillary Morphogenesis Protein-2 Based Decoys as Anthrax Toxin Inhibitors.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020646

By:

Chenguang Cai;
Jinjing Che;
Long Xu;
Qiang Guo;
Yirong Kong;
Ling Fu;
Junjie Xu;
Yuanguo Cheng;
Wei Chen

Publication type:

Article

Anthrax Toxin Uptake by Primary Immune Cells as Determined with a Lethal Factor-β-Lactamase Fusion Protein.

Published in:: PLoS ONE, 2009, v. 4, n. 11, p. 1, doi. 10.1371/journal.pone.0007946
Publication type:: Article

Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91596-3

By:

Machen, Alexandra J.;
Fisher, Mark T.;
Freudenthal, Bret D.

Publication type:

Article

A microfluidic live cell assay to study anthrax toxin induced cell lethality assisted by conditioned medium.

Published in:

Scientific Reports, 2015, p. 8651, doi. 10.1038/srep08651

By:

Shen, Jie;
Cai, Changzu;
Yu, Zhilong;
Pang, Yuhong;
Zhou, Ying;
Qian, Lili;
Wei, Wensheng;
Huang, Yanyi

Publication type:

Article

Atomic structure of anthrax protective antigen pore elucidates toxin translocation.

Published in:

Nature, 2015, v. 521, n. 7553, p. 545, doi. 10.1038/nature14247

By:

Jiang, Jiansen;
Pentelute, Bradley L.;
Collier, R. John;
Zhou, Z. Hong

Publication type:

Article

Biochip for the Detection of Bacillus anthracis Lethal Factor and Therapeutic Agents against Anthrax Toxins.

Published in:

Membranes, 2016, v. 6, n. 3, p. 36, doi. 10.3390/membranes6030036

By:

Silin, Vitalii;
Kasianowicz, John J.;
Michelman-Ribeiro, Ariel;
Panchal, Rekha G.;
Bavari, Sina;
Robertson, Joseph W. F.

Publication type:

Article

The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49100-5

By:

Cheng, Baixiang;
Liu, Yanzheng;
Zhao, Ying;
Li, Qiang;
Liu, Yanli;
Wang, Junjun;
Chen, Yongjin;
Zhang, Min

Publication type:

Article

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

Published in:

2017

By:

Miles, Linde A.;
Burga, Laura N.;
Gardner, Eric E.;
Bostina, Mihnea;
Poirier, John T.;
Rudin, Charles M.

Publication type:

journal article

High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures.

Published in:

Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 10, p. 2847, doi. 10.1007/s00216-015-8509-5

By:

Boyer, Anne;
Gallegos-Candela, Maribel;
Quinn, Conrad;
Woolfitt, Adrian;
Brumlow, Judith;
Isbell, Katherine;
Hoffmaster, Alex;
Lins, Renato;
Barr, John

Publication type:

Article

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062576

By:

D’Agnillo, Felice;
Williams, Matthew C.;
Moayeri, Mahtab;
Warfel, Jason M.

Publication type:

Article

Suppressive Effects of Anthrax Lethal Toxin on Megakaryopoiesis.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059512

By:

Chen, Po-Kong;
Chang, Hsin-Hou;
Lin, Guan-Ling;
Wang, Tsung-Pao;
Lai, Yi-Ling;
Lin, Ting-Kai;
Hsieh, Ming-Chun;
Kau, Jyh-Hwa;
Huang, Hsin-Hsien;
Hsu, Hui-Ling;
Liao, Chi-Yuan;
Sun, Der-Shan

Publication type:

Article

Regulation of Anthrax Toxin-Specific Antibody Titers by Natural Killer T Cell-Derived IL-4 and IFN&ggr;.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023817

By:

Devera, T. Scott;
Joshi, Sunil K.;
Aye, Lindsay M.;
Lang, Gillian A.;
Ballard, Jimmy D.;
Lang, Mark L.

Publication type:

Article

Efficient Targeting of Head and Neck Squamous Cell Carcinoma by Systemic Administration of a Dual uPA and MMP-Activated Engineered Anthrax Toxin.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020532

By:

Schafer, Jeffrey M.;
Peters, Diane E.;
Morley, Thomas;
Liu, Shihui;
Molinolo, Alfredo A.;
Leppla, Stephen H.;
Bugge, Thomas H.

Publication type:

Article

Anthrax toxin receptor 2a controls mitotic spindle positioning.

Published in:

Nature Cell Biology, 2013, v. 15, n. 1, p. 28, doi. 10.1038/ncb2632

By:

Castanon, I.;
Abrami, L.;
Holtzer, L.;
Heisenberg, C. P.;
van der Goot, F. G.;
González-Gaitán, M.

Publication type:

Article

A Dual Role for the Bacillus anthracis Master Virulence Regulator AtxA: Control of Sporulation and Anthrax Toxin Production.

Published in:

Frontiers in Microbiology, 2018, p. 1, doi. 10.3389/fmicb.2018.00482

By:

Dale, Jennifer L.;
Raynor, Malik J.;
Ty, Maureen C.;
Hadjifrangiskou, Maria;
Koehler, Theresa M.

Publication type:

Article

A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006530

By:

Herrera, Bobby Brooke;
Hamel, Donald J.;
Oshun, Philip;
Akinsola, Rolake;
Akanmu, Alani S.;
Chang, Charlotte A.;
Eromon, Philomena;
Folarin, Onikepe;
Adeyemi, Kayode T.;
Happi, Christian T.;
Lu, Yichen;
Ogunsola, Folasade;
Kanki, Phyllis J.

Publication type:

Article

Quantitative anti-PA IgG ELISA; assessment and comparability with the anthrax toxin neutralization assay in goats.

Published in:

BMC Veterinary Research, 2013, v. 9, n. 1, p. 1, doi. 10.1186/1746-6148-9-265

By:

Ndumnego, Okechukwu C.;
Crafford, Jannie;
Beyer, Wolfgang;
van Heerden, Henriette

Publication type:

Article

An anthrax toxin variant with an improved activity in tumor targeting.

Published in:

Scientific Reports, 2015, p. 16267, doi. 10.1038/srep16267

By:

Peters, Diane E.;
Wein, Alexander N.;
Valivullah, Zaheer;
Hoover, Benjamin J.;
Tatineni, Aparna;
Ma, Qian;
Fattah, Rasem;
Leppla, Stephen H.;
Liu, Shihui;
Bugge, Thomas H.

Publication type:

Article

Molecular Motions as a Drug Target: Mechanistic Simulations of Anthrax Toxin Edema Factor Function Led to the Discovery of Novel Allosteric Inhibitors.

Published in:

Toxins, 2012, v. 4, n. 8, p. 580, doi. 10.3390/toxins4080580

By:

Laine, Élodie;
Martínez, Leandro;
Ladant, Daniel;
Malliavin, Thérèse;
Blondel, Arnaud

Publication type:

Article

Protective Antigen Antibody Augments Hemodynamic Support in Anthrax Lethal Toxin Shock in Canines.

Published in:

Journal of Infectious Diseases, 2012, v. 205, n. 5, p. 818, doi. 10.1093/infdis/jir834

By:

Barochia, Amisha V.;
Xizhong Cui;
Junfeng Sun;
Yan Li;
Solomon, Steven B.;
Migone, Thi-Sau;
Subramanian, G. Mani;
Bolmer, Sally D.;
Eichacker, Peter Q.

Publication type:

Article

Anthrax Toxin-Expressing Bacillus cereus Isolated from an Anthrax-Like Eschar.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156987

By:

Marston, Chung K.;
Ibrahim, Hisham;
Lee, Philip;
Churchwell, George;
Gumke, Megan;
Stanek, Danielle;
Gee, Jay E.;
Boyer, Anne E.;
Gallegos-Candela, Maribel;
Barr, John R.;
Li, Han;
Boulay, Darbi;
Cronin, Li;
Quinn, Conrad P.;
Hoffmaster, Alex R.

Publication type:

Article

Reductive Methylation and Mutation of an Anthrax Toxin Fusion Protein Modulates its Stability and Cytotoxicity.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04754

By:

Bachran, Christopher;
Gupta, Pradeep K.;
Bachran, Silke;
Leysath, Clinton E.;
Hoover, Benjamin;
Fattah, Rasem J.;
Leppla, Stephen H.

Publication type:

Article

Identification of Potential Therapeutic Targets Against Anthrax-Toxin-Induced Liver and Heart Damage.

Published in:

Toxins, 2025, v. 17, n. 2, p. 54, doi. 10.3390/toxins17020054

By:

Wu, Lihong;
Chen, Yanping;
Yan, Yongyong;
Wang, Haiyan;
Guy, Cynthia D.;
Carney, John;
Moreno, Carla L.;
Quintanilla-Arteaga, Anaisa;
Monsivais, Fernando;
Zheng, Zhichao;
Zeng, Mingtao

Publication type:

Article

The Ins and Outs of Anthrax Toxin.

Published in:

Toxins, 2016, v. 8, n. 3, p. 69, doi. 10.3390/toxins8030069

By:

Friebe, Sarah;
van der Goot, F. Gisou;
Bürgi, Jérôme

Publication type:

Article

A novel, safe, fast and efficient treatment for Her2‐positive and negative bladder cancer utilizing an EGF‐anthrax toxin chimera.

Published in:

International Journal of Cancer, 2020, v. 146, n. 2, p. 449, doi. 10.1002/ijc.32719

By:

Jack, Sherwin;
Madhivanan, Kayalvizhi;
Ramadesikan, Swetha;
Subramanian, Sneha;
Edwards, Daniel F.;
Elzey, Bennett D.;
Dhawan, Deepika;
McCluskey, Andrew;
Kischuk, Erin M.;
Loftis, Alexander R.;
Truex, Nicholas;
Santos, Michael;
Lu, Mike;
Rabideau, Amy;
Pentelute, Bradley;
Collier, John;
Kaimakliotis, Hristos;
Koch, Michael;
Ratliff, Timothy L.;
Knapp, Deborah W.

Publication type:

Article

Quantitative Determination of Lethal Toxin Proteins in Culture Supernatant of Human Live Anthrax Vaccine Bacillus anthracis A16R.

Published in:

Toxins, 2016, v. 8, n. 3, p. 56, doi. 10.3390/toxins8030056

By:

Xiaodong Zai;
Jun Zhang;
Ju Liu;
Jie Liu;
Liangliang Li;
Ying Yin;
Ling Fu;
Junjie Xu;
Wei Chen

Publication type:

Article

Anthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression.

Published in:

Toxins, 2016, v. 8, n. 1, p. 1, doi. 10.3390/toxins8010001

By:

Zhang Zhang;
Yan Zhang;
Minglei Shi;
Bingyu Ye;
Wenlong Shen;
Ping Li;
Lingyue Xing;
Xiaopeng Zhang;
Lihua Hou;
Junjie Xu;
Zhihu Zhao;
Wei Chen

Publication type:

Article

CMG2-Fc 融合蛋白突变体筛选及中和炭疽毒素活性分析.

Published in:

Progress in Modern Biomedicine, 2016, v. 16, n. 8, p. 1601, doi. 10.13241/j.cnki.pmb.2016.09.001

By:

刘宗伟;
任雨春;
郗永义;
岳俊杰1;
张连成;
邵勇;
高丽华;
胡显文;
周艳荣;
吴晓洁;
陈红星

Publication type:

Article

Fusion protein of Δ27LFn and EFn has the potential as a novel anthrax toxin inhibitor

Published in:

FEBS Letters, 2009, v. 583, n. 8, p. 1257, doi. 10.1016/j.febslet.2009.03.053

By:

Kong, Yirong;
Guo, Qiang;
Yu, Changming;
Dong, Dayong;
Zhao, Jian;
Cai, Chenguang;
Hou, Lihua;
Song, Xiaohong;
Fu, Ling;
Xu, Junjie;
Chen, Wei

Publication type:

Article

Anthrax toxin: a tripartite lethal combination1<FN ID="FN1"><NO>1</NO>This paper is dedicated to the memory of the victims of bioterrorism.</FN>

Published in:

FEBS Letters, 2002, v. 531, n. 3, p. 384, doi. 10.1016/S0014-5793(02)03609-8

By:

Ascenzi, Paolo;
Visca, Paolo;
Ippolito, Giuseppe;
Spallarossa, Andrea;
Bolognesi, Martino;
Montecucco, Cesare

Publication type:

Article

Rat survival to anthrax lethal toxin is likely controlled by a single gene.

Published in:

Pharmacogenomics Journal, 2008, v. 8, n. 1, p. 16, doi. 10.1038/sj.tpj.6500448

By:

Nye, S. H.;
Wittenburg, A. L.;
Evans, D. L.;
O'Connor, J. A.;
Roman, R. J.;
Jacob, H. J.

Publication type:

Article

A complex role of anthrax toxin receptor 2 polymorphisms and capillary morphogenesis protein 2 in ankylosing spondylitis pathogenesis.

Published in:

Clinical Rheumatology, 2016, v. 35, n. 9, p. 2243, doi. 10.1007/s10067-015-3158-9

By:

Zhang, Zhijian;
Yu, Kun;
Dai, Dongfa;
Yuan, Fang;
Liang, Fei;
Liu, Nan;
Xi, Yongzhi;
Sun, Yu-Ying

Publication type:

Article

A new triple chimeric protein as a high immunogenic antigen against anthrax toxins: theoretical and experimental analyses.

Published in:

Immunopharmacology & Immunotoxicology, 2019, v. 41, n. 1, p. 25, doi. 10.1080/08923973.2018.1510419

By:

Abdous, Masoud;
Hasannia, Sadegh;
Salmanian, Ali Hatef;
Shahryar Arab, Seyed;
Shali, Abbas;
Alizadeh, Ghorban Ali;
Hajizadeh, Afshin;
Khafri, Abolfazl;
Mohseni, Ammar

Publication type:

Article

Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12424

By:

EL-CHAMI, DANA;
AL HADDAD, MARIA;
ABI-HABIB, RALPH;
EL-SIBAI, MIRVAT

Publication type:

Article

HDAC8 Prevents Anthrax Lethal Toxin-Induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells.

Published in:

Toxins, 2017, v. 9, n. 5, p. 162, doi. 10.3390/toxins9050162

By:

Soon-Duck Ha;
Woohyun Cho;
Sung Ouk Kim

Publication type:

Article

Anthrax Toxins in Context of Bacillus anthracis Spores and Spore Germination.

Published in:

Toxins, 2015, v. 7, n. 8, p. 3167, doi. 10.3390/toxins7083167

By:

Cote, Christopher K.;
Welkos, Susan L.

Publication type:

Article