Works matching DE "PYRIMIDINE synthesis"

Results: 391

Titelbild: Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine (Angew. Chem. 38/2016).

Published in:

Angewandte Chemie, 2016, v. 128, n. 38, p. 11473, doi. 10.1002/ange.201606538

By:

Matveenko, Maria;
Cichero, Elena;
Fossa, Paola;
Becker, Christian F. W.

Publication type:

Article

Regulation of carbamoylphosphate synthesis in Escherichia coli: an amazing metabolite at the crossroad of arginine and pyrimidine biosynthesis.

Published in:

Amino Acids, 2018, v. 50, n. 12, p. 1647, doi. 10.1007/s00726-018-2654-z

By:

Charlier, Daniel;
Nguyen Le Minh, Phu;
Roovers, Martine

Publication type:

Article

Synthesis and Pharmacological Activities of Pyrano[2,3-d]pyrimidine and Pyrano[2,3-d]pyrimidine-5-one Derivatives as New Fused Heterocyclic Systems.

Published in:

Journal of Chemistry, 2017, p. 1, doi. 10.1155/2017/5373049

By:

Mahmoud, Naglaa F. H.;
El-Bordany, Eman A.;
Elsayed, Galal A.

Publication type:

Article

Nano-basic silica as an efficient catalyst for the multi-component preparation of pyrano[2,3-d] pyrimidine derivatives.

Published in:

Main Group Metal Chemistry, 2017, v. 40, n. 1/2, p. 19, doi. 10.1515/mgmc-2016-0034

By:

Sheikhan-Shamsabadi, Nafisehsadat;
Ghashang, Majid

Publication type:

Article

One‐Pot Synthesis of 6‐Aminopyrido[2,3‐d]pyrimidin‐7‐ones.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 46, p. 6519, doi. 10.1002/ejoc.201801204

By:

Zinchenko, Anna M.;
Muzychka, Lyubov V.;
Kucher, Olexandr V.;
Sadkova, Iryna V.;
Mykhailiuk, Pavel K.;
Smolii, Oleg B.

Publication type:

Article

Synthesis and Biological Activity of Oxazolopyrimidines.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 19, p. 2148, doi. 10.1002/ejoc.201800133

By:

De Coen, Laurens M.;
Roman, Bart I.;
Movsisyan, Marine;
Heugebaert, Thomas S. A.;
Stevens, Christian V.

Publication type:

Article

An Organocatalytic Synthesis of Chiral Pyrano[2,3-d]pyrimidines through [3+3] Annulation of 1,3-Dimethyl-barbituric Acid with 2-(1-Alkynyl)-2-alken-1-ones.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 3, p. 347, doi. 10.1002/ejoc.201701581

By:

Zhu, Yali;
Wang, Zhonghe;
Zhang, Jing;
Yu, Jia;
Yan, Lijuan;
Li, Yang;
Chen, Ligong;
Yan, Xilong

Publication type:

Article

Efficient Synthesis of (1,2,3-Triazol-1-yl)methylpyrimidines from 5-Bromo-1,1,1-trifluoro-4-methoxypent-3-en-2-one.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 2, p. 306, doi. 10.1002/ejoc.201601234

By:

Aquino, Estefania da C.;
Lobo, Marcio M.;
Leonel, Guilherme;
Martins, Marcos A. P.;
Bonacorso, Helio G.;
Zanatta, Nilo

Publication type:

Article

Three-Component Bicyclization Leading to Densely Functionalized Pyrazolo[3,4- d]thiazolo[3,2- a]pyrimidines.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 11, p. 1968, doi. 10.1002/ejoc.201600163

By:

Hao, Wen‐Juan;
Zhou, Peng;
Wu, Fei‐Yue;
Jiang, Bo;
Tu, Shu‐Jiang;
Li, Guigen

Publication type:

Article

Time-Efficient Synthesis of Pyrido[2,3- d]pyrimidinones via α-Oxoketenes.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 11, p. 1994, doi. 10.1002/ejoc.201600171

By:

Castillo, Juan‐Carlos;
Quiroga, Jairo;
Rodriguez, Jean;
Coquerel, Yoann

Publication type:

Article

Heteroacenes Bearing the Pyrimidine Scaffold: Synthesis, Photophysical and Electrochemical Properties.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 7, p. 1420, doi. 10.1002/ejoc.201501450

By:

Verbitskiy, Egor V.;
Cheprakova, Ekaterina M.;
Makarova, Nadezhda I.;
Dorogan, Igor V.;
Metelitsa, Anatoly V.;
Minkin, Vladimir I.;
Slepukhin, Pavel A.;
Svalova, Tatyana S.;
Ivanova, Alla V.;
Kozitsina, Alisa N.;
Rusinov, Gennady L.;
Chupakhin, Oleg N.;
Charushin, Valery N.

Publication type:

Article

Solvent-Free Synthesis of 4 H-Pyrido[1,2- a]pyrimidin-4-ones Catalyzed by BiCl3: A Green Route to a Privileged Backbone.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 11, p. 2351, doi. 10.1002/ejoc.201500227

By:

Roslan, Irwan I.;
Lim, Qiu‐Xuan;
Han, Aijuan;
Chuah, Gaik‐Khuan;
Jaenicke, Stephan

Publication type:

Article

Synthesis, Structure, and Conformational Analysis of Nucleoside Analogues Comprising Six-Membered 1,3-Oxathiane Sugar Rings.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 9, p. 1945, doi. 10.1002/ejoc.201403642

By:

Abou Assi, Hala;
Martínez‐Montero, Saúl;
Dixit, Dilip M.;
Chua, Zhijie;
Bohle, D. Scott;
Damha, Masad J.

Publication type:

Article

Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 6, p. 1235, doi. 10.1002/ejoc.201403473

By:

Battisti, Umberto M.;
Sorbi, Claudia;
Quotadamo, Antonio;
Franchini, Silvia;
Tait, Annalisa;
Schols, Dominique;
Jeong, Lak Shin;
Lee, Sang Kook;
Song, Jayoung;
Brasili, Livio

Publication type:

Article

Synthesis of Soai Type 2-Arylpyrimidine-5-carbaldehydes through Desulfurative Cross-Coupling with Arylboronic Acids.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 33, p. 7426, doi. 10.1002/ejoc.201403133

By:

Maltsev, Oleg V.;
Rausch, Rodger;
Quan, Zheng‐Jun;
Hintermann, Lukas

Publication type:

Article

Cleavage of 2-(Arylamino)-4,6-dimethoxypyrimidines To Yield Arylguanidines.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 17, p. 3565, doi. 10.1002/ejoc.201402179

By:

Shaw, Julian W.;
Grayson, David H.;
Rozas, Isabel

Publication type:

Article

Retro-Diels-Alder Protocol for the Synthesis of Pyrrolo[1,2- a]pyrimidine and Pyrimido[2,1- a]isoindole Enantiomers.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 22, p. 4887, doi. 10.1002/ejoc.201300452

By:

Miklós, Ferenc;
Tóth, Zita;
Hänninen, Mikko M.;
Sillanpää, Reijo;
Forró, Enikő;
Fülöp, Ferenc

Publication type:

Article

Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation.

Published in:

Green Chemistry Letters & Reviews, 2018, v. 11, n. 2, p. 62, doi. 10.1080/17518253.2018.1437225

By:

Dehbi, Oussama;
Ishak, Esam A.;
Bakht, Mohammed A.;
Geesi, Mohammed H.;
Alshammari, Mohammed B.;
Chagnault, Vincent;
Kaiba, Abdellah;
Lazar, Saïd;
Riadi, Yassine

Publication type:

Article

Green chemistry multicomponent protocol for formylation and Knoevenagel condensation for synthesis of (Z)-5-arylaminomethylene pyrimidine 2, 4, 6-trione derivatives in water.

Published in:

Green Chemistry Letters & Reviews, 2014, v. 7, n. 1, p. 1, doi. 10.1080/17518253.2013.869839

By:

Dhorajiya, Bhaveshkumar D.;
Dholakiya, Bharatkumar Z.

Publication type:

Article

Efficient and environmentally benign synthetic protocol for the synthesis of structurally diverse annulated pyridopyrimidines.

Published in:

Green Chemistry Letters & Reviews, 2014, v. 7, n. 1, p. 37, doi. 10.1080/17518253.2014.895057

By:

Rajawat, Anshu;
Khandelwal, Sarita;
Kumar, Mahendra

Publication type:

Article

Synthesis and In vitro Activity of N-sulfonylamidine-derived Pyrimidine Analogues.

Published in:

Croatica Chemica Acta, 2017, v. 90, n. 4, p. 625, doi. 10.5562/cca3273

By:

Krstulović, Luka;
Saftić, Dijana;
Ismaili, Hamit;
Bajić, Miroslav;
Glavaš-Obrovac, Ljubica;
Žinić, Biserka

Publication type:

Article

Michael Cyclization of Polarized Systems: Synthesis and in vitro Anti-Diabetic Evaluation of Some Novel Pyrimidine, Pyridine, Pyrazole and Pyrazolo[3,4-b ]pyridine Derivatives.

Published in:

Croatica Chemica Acta, 2017, v. 90, n. 3, p. 461, doi. 10.5562/cca3122

By:

Soylem, Essam A.;
Assy, Mohammed G.;
Morsi, Ghania M.

Publication type:

Article

Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity.

Published in:

PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003678

By:

Lucas-Hourani, Marianne;
Dauzonne, Daniel;
Jorda, Pierre;
Cousin, Gaëlle;
Lupan, Alexandru;
Helynck, Olivier;
Caignard, Grégory;
Janvier, Geneviève;
André-Leroux, Gwénaëlle;
Khiar, Samira;
Escriou, Nicolas;
Desprès, Philippe;
Jacob, Yves;
Munier-Lehmann, Hélène;
Tangy, Frédéric;
Vidalain, Pierre-Olivier

Publication type:

Article

Cover Feature: Synthesis of Mono‐ and Bis(fluoroalkyl)pyrimidines from FARs, Fluorinated Acetoacetates, and Malononitrile Provides Easy Access to Novel High‐Value Pyrimidine Scaffolds (Chem. Eur. J. 6/2018).

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 6, p. 1219, doi. 10.1002/chem.201704992

By:

Schmitt, Etienne;
Commare, Bruno;
Panossian, Armen;
Vors, Jean‐pierre;
Pazenok, Sergiy;
Leroux, Frédéric R.

Publication type:

Article

Synthesis of Pyrrolo[2,3- d]pyrimidines by Copper-Mediated Carbomagnesiations of N-Sulfonyl Ynamides and Application to the Preparation of Rigidin A and a 7-Azaserotonin Derivative.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 40, p. 14397, doi. 10.1002/chem.201602519

By:

Nickel, Johannes;
Fernández, Maitane;
Klier, Lydia;
Knochel, Paul

Publication type:

Article

Copper-Catalyzed Domino Synthesis of Benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-ones using Cyanamide as a Building Block.

Published in:

Advanced Synthesis & Catalysis, 2015, v. 357, n. 18, p. 3961, doi. 10.1002/adsc.201500577

By:

Lou, Zhenbang;
Wu, Xudong;
Yang, Haijun;
Zhu, Changjin;
Fu, Hua

Publication type:

Article

Intracrine action of angiotensin II in mesangial cells: subcellular distribution of angiotensin II receptor subtypes AT1 and AT2.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 448, n. 1/2, p. 265, doi. 10.1007/s11010-018-3331-y

By:

da Silva Novaes, Antônio;
Ribeiro, Rosemara Silva;
Pereira, Luciana Guilhermino;
Borges, Fernanda Teixeira;
Boim, Mirian Aparecida

Publication type:

Article

Effects of extracellular orotic acid on acute contraction-induced adaptation patterns in C2C12 cells.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 448, n. 1/2, p. 251, doi. 10.1007/s11010-018-3330-z

By:

Beiter, Thomas;
Hudemann, Jens;
Burgstahler, Christof;
Nieß, Andreas M.;
Munz, Barbara

Publication type:

Article

Synthesis of 3H, 2H4 and 14C-SCH 417690 (Vicriviroc).

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 5, p. 190, doi. 10.1002/jlcr.3387

By:

Hesk, D.;
Borges, S.;
Hendershot, S.;
Koharski, D.;
McNamara, P.;
Ren, S.;
Saluja, S.;
Truong, V.;
Voronin, K.

Publication type:

Article

Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

Published in:

Nature, 2015, v. 527, n. 7578, p. 379, doi. 10.1038/nature15529

By:

Rabinovich, Shiran;
Adler, Lital;
Yizhak, Keren;
Sarver, Alona;
Silberman, Alon;
Agron, Shani;
Stettner, Noa;
Sun, Qin;
Brandis, Alexander;
Helbling, Daniel;
Korman, Stanley;
Itzkovitz, Shalev;
Dimmock, David;
Ulitsky, Igor;
Nagamani, Sandesh C. S.;
Ruppin, Eytan;
Erez, Ayelet

Publication type:

Article

Synthesis and Characterization of Some Pyrimidine Derivatives from Dimethyl Malonate and Evaluation their Biological Activity.

Published in:

Diyala Journal for Pure Science, 2019, v. 15, n. 2, p. 131, doi. 10.24237/djps.15.02.494B

By:

Mahmood, Sajed Khalil;
Rasheed, Malath Khalaf

Publication type:

Article

Orotate (orotic acid): An essential and versatile molecule.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2016, v. 35, n. 10-12, p. 566, doi. 10.1080/15257770.2016.1147580

By:

Löffler, M.;
Carrey, E.A.;
Zameitat, E.

Publication type:

Article

A New Efficient Stereoselective Method for the Synthesis of ( E )-5-Aminoallyl-Pyrimidine-5′-Triphosphates Using Palladium-Catalyzed Heck Reaction.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2015, v. 34, n. 3, p. 221, doi. 10.1080/15257770.2014.978013

By:

Kore, Anilkumar R.;
Senthilvelan, Annamalai;
Shanmugasundaram, Muthian;
Sandoval, David;
Pardo, Andrew

Publication type:

Article

A New Route for the Synthesis of 4-Amino-5-Fluoro-7-(2′-Deoxy-2′-Fluoro-2′- C -Methyl- β - d - Ribofuranosyl)-1 H -Pyrrolo[2,3-D]Pyrimidine.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2013, v. 32, n. 7, p. 389, doi. 10.1080/15257770.2013.797994

By:

Hu, Weidong;
Yang, Qinghua;
Wang, Shuyang;
Huang, Gang;
Zhang, Yueteng;
Dong, Jingjing;
Kang, Jinfeng;
Song, Chuanjun;
Chang, Junbiao

Publication type:

Article

Synthesis and biological evaluation of novel fused triazolo[4,3-a] pyrimidinones.

Published in:

Turkish Journal of Chemistry, 2015, v. 39, n. 3, p. 510, doi. 10.3906/kim-1501-144

By:

ABBAS, Ikhlass;
GOMHA, Sobhi;
ELNEAIRY, Mohamed;
ELAASSER, Mahmoud;
MABROUK, Bazada

Publication type:

Article

The First Catalytic Direct C–H Arylation on C2 and C3 of Thiophene Ring Applied to Thieno-Pyridines, -Pyrimidines and -Pyrazines.

Published in:

Catalysts (2073-4344), 2018, v. 8, n. 4, p. 137, doi. 10.3390/catal8040137

By:

Campos, Joana F.;
Queiroz, Maria-João R. P.;
Berteina-Raboin, Sabine

Publication type:

Article

Synthesis of β-C-Linked 2-Arylaminopyrimidines and β-Cyclohexenone C-Glycosides as H3 Receptor Antagonists.

Published in:

Trends in Carbohydrate Research, 2017, v. 9, n. 3, p. 26

By:

Singh, Kartikey;
Kumar, Ajeet;
Baranwa, Pragati;
Yadav, Prem Naryan;
Tripath, Rama Pati

Publication type:

Article

STRAIGHTFORWARD MULTICOMPONENT SYNTHESIS AND MICROBIAL SCREENING OF 2-CYANOAMINO-1, 2-DIHYDROPYRIMIDINES BEARING INDOLE SIDE CORE.

Published in:

Journal of Advanced Scientific Research, 2021, v. 12, n. 2, p. 71

By:

Vignesh, C.;
Ingarsal, N.

Publication type:

Article

SYNTHESIS, CHARACTERIZATION & BIOLOGICAL EVALUATION OF SOME NOVEL PYRIDO[1,2-A] PYRIMIDIN-4-ONE DERIVATIVES.

Published in:

Journal of Advanced Scientific Research, 2020, v. 11, n. 3, p. 225

By:

Butani, Pankaj C.;
Bheshdadia, Bhagvanji M.;
Ladva, Kartik D.

Publication type:

Article

Synthesis of some novel pyrazolo[3,4-d] pyrimidin-4(5H)-one derivatives as potential antimicrobial agent.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2016, v. 8, n. 4, p. 321, doi. 10.4103/0975-7406.199337

By:

Sureja, Dipen K.;
Dholakia, Sandip P.;
Vadalia, Kantilal R.

Publication type:

Article

Synthesis, characterization and in silico biological activity of some 2-(N,N-dimethyl guanidinyl)-4,6-diaryl pyrimidines.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2016, v. 8, n. 3, p. 181, doi. 10.4103/0975-7406.171678

By:

Kumarachari, Rajasekhar Komarla;
Peta, Sivakumar;
Surur, Abdrrahman Shemsu;
Mekonnen, Yenus Tadesse

Publication type:

Article

Synthesis, antifungal activity, and QSAR studies of 1,6-dihydropyrimidine derivatives.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2013, v. 5, n. 4, p. 277, doi. 10.4103/0975-7406.120078

By:

Rami, Chirag;
Patel, Laxmanbhai;
Patel, Chhaganbhai N.;
Parmar, Jayshree P.

Publication type:

Article

Multicomponent Strategy for the Preparation of Pyrrolo[1,2- a]pyrimidine Derivatives under Catalyst-Free and Microwave Irradiation Conditions.

Published in:

Chinese Journal of Chemistry, 2016, v. 34, n. 7, p. 696, doi. 10.1002/cjoc.201600142

By:

Xun, Zhan;
Feng, Xian;
Wang, Jianjun;
Shi, Daqing;
Huang, Zhibin

Publication type:

Article

Synthesis and Structure of Azacalix[2]pyrimidine[2]triazines and Their Self-assembly in the Solid State.

Published in:

Chinese Journal of Chemistry, 2014, v. 32, n. 10, p. 1033, doi. 10.1002/cjoc.201400505

By:

Wang, Lixia;
Wang, Dexian;
Wang, Meixiang

Publication type:

Article

Diastereoselective Synthesis of Functionalized Tetrahydropyrimidin-2-thiones via ZnCl2 Promoted One-pot Reactions.

Published in:

Chinese Journal of Chemistry, 2014, v. 32, n. 2, p. 172, doi. 10.1002/cjoc.201300577

By:

Liu, Zhenming;
Zhang, Lili;
Sun, Jing;
Yan, Chaoguo

Publication type:

Article

A Novel Yae1p-Dependent Mechanism and Modulation of the Pyrimidine Biosynthetic Pathway can both Confer Resistance to 5-Fluorouracil in Yeast.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0052094

By:

Carlsson, Mattias;
Gustavsson, Marie;
Hu, Guo-Zhen;
Murén, Eva;
Ronne, Hans

Publication type:

Article

Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058034

By:

Ali, Juma A. M.;
Tagoe, Daniel N. A.;
Munday, Jane C.;
Donachie, Anne;
Morrison, Liam J.;
de Koning, Harry P.

Publication type:

Article

Leflunomide is a possible deactivator for vitiligo, a pilot study.

Published in:

Journal of the European Academy of Dermatology & Venereology, 2012, v. 26, n. 9, p. 1173, doi. 10.1111/j.1468-3083.2011.04311.x

By:

Awad, S.S.

Publication type:

Article

Pyrimidine‐based pyrazoles as cyclin‐dependent kinase 2 inhibitors: Design, synthesis, and biological evaluation.

Published in:

Chemical Biology & Drug Design, 2018, v. 92, n. 3, p. 1683, doi. 10.1111/cbdd.13334

By:

Vekariya, Mayur K.;
Vekariya, Rajesh H.;
Brahmkshatriya, Pathik S.;
Shah, Nisha K.

Publication type:

Article

Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase.

Published in:

Chemical Biology & Drug Design, 2018, v. 92, n. 1, p. 1324, doi. 10.1111/cbdd.13197

By:

Lang, Li;
Hu, Qian;
Wang, Jingyuan;
Liu, Zehui;
Huang, Jin;
Lu, Weiqiang;
Huang, Ying

Publication type:

Article