Works matching DE "PROTEASE-activated receptors"
Results: 468
Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.
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- Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 8, p. 625, doi. 10.1007/s10822-016-9937-9
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Improving homology modeling of G-protein coupled receptors through multiple-template derived conserved inter-residue interactions.
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- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 5, p. 413, doi. 10.1007/s10822-014-9823-2
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Specifically targeting cancer proliferation and metastasis processes: the development of matriptase inhibitors.
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- Cancer & Metastasis Reviews, 2019, v. 38, n. 3, p. 507, doi. 10.1007/s10555-019-09802-8
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New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?
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- Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 12, p. 1671, doi. 10.1007/s00424-013-1284-2
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Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation.
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- Pflügers Archiv: European Journal of Physiology, 2012, v. 463, n. 3, p. 497, doi. 10.1007/s00424-011-1064-9
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High-resolution crystal structure of human protease-activated receptor 1.
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- Nature, 2012, v. 492, n. 7429, p. 387, doi. 10.1038/nature11701
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ALIX binds a YPX<sub>3</sub>L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting.
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- Journal of Cell Biology, 2012, v. 197, n. 3, p. 407, doi. 10.1083/jcb.201110031
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The effect of exogenous activation of protease-activated receptor 2 on cutaneous vasodilatation and sweating in young males during rest and exercise in the heat.
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- Temperature, 2018, v. 5, n. 3, p. 257, doi. 10.1080/23328940.2018.1506563
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SCH 79797, a selective PAR1 antagonist, protects against ischemia/reperfusion-induced arrhythmias in the rat hearts.
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- European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 22, p. 4796
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Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells.
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- European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 22, p. 4688
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Clinical significance of serum protease activated receptor1 levels in patients with lung cancer.
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- European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 2, p. 243
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Electroacupuncture Relieves Visceral Hypersensitivity via Balancing PAR2 and PAR4 in the Descending Pain Modulatory System of Goats.
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- Brain Sciences (2076-3425), 2023, v. 13, n. 6, p. 922, doi. 10.3390/brainsci13060922
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Nociceptive Sensitization by Activation of Protease-Activated Receptor 2 in a Rat Model of Incisional Pain.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 2, p. 144, doi. 10.3390/brainsci11020144
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Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells.
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- Brain Sciences (2076-3425), 2020, v. 10, n. 12, p. 959, doi. 10.3390/brainsci10120959
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Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria.
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- Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00056
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Regional Differences in Chronic Stress-induced Alterations in Mast Cell and Protease-activated Receptor-2-positive Cell Numbers in the Colon of Ws/Ws Rats.
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- Journal of Neurogastroenterology & Motility, 2014, v. 20, n. 1, p. 54, doi. 10.5056/jnm.2014.20.1.54
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A Linear Temporal Increase in Thrombin Activity and Loss of Its Receptor in Mouse Brain following Ischemic Stroke.
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- Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00138
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Biased Signaling of Protease-activated Receptors.
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- Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00067
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Вплив пригнічення функції протеазаактивованих рецепторів 1 у латентний період розвитку скроневої епілепсії на депресивноподібну поведінку щурів
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- Physiological Journal / Fiziologichnyi Zhurnal, 2020, v. 66, n. 5, p. 17
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Селективний антагоніст протеазоактивованих рецепторів 1 нормалізує рівень емоційної збудливості щурів у латентній стадії формування скроневої епілепсії.
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- Physiological Journal / Fiziologichnyi Zhurnal, 2019, v. 65, n. 3, p. 7
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The protease-activated receptor 1 inhibition during epileptogenesis does not alter behavioral excitability in rats.
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- Physiological Journal / Fiziologichnyi Zhurnal, 2018, v. 64, n. 2, p. 12, doi. 10.15407/fz64.02.012
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Xa inhibitor edoxaban ameliorates hepatic ischemia-reperfusion injury via PAR-2–ERK 1/2 pathway.
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- PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0292628
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Unmet needs in the management of acute myocardial infarction: role of novel protease-activated receptor-1 antagonist vorapaxar.
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- Vascular Health & Risk Management, 2014, v. 10, p. 177, doi. 10.2147/VHRM.S36045
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Thrombin regulation of synaptic transmission and plasticity: implications for health and disease.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00151
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Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism.
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- Journal of Orthopaedic Research, 2014, v. 32, n. 12, p. 1549, doi. 10.1002/jor.22726
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Fracture healing in protease-activated receptor-2 deficient mice.
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- Journal of Orthopaedic Research, 2012, v. 30, n. 8, p. 1271, doi. 10.1002/jor.22071
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Inhibition of melanin synthesis and melanosome transfer by chitosan biomaterials.
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- Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2020, v. 108, n. 4, p. 1239, doi. 10.1002/jbm.b.34472
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A New Strategy in Modulating the Protease-Activated Receptor 2 (Par2) in Autoimmune Diseases.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 410, doi. 10.3390/ijms26010410
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Atrial Fibrosis in Atrial Fibrillation: Mechanistic Insights, Diagnostic Challenges, and Emerging Therapeutic Targets.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 209, doi. 10.3390/ijms26010209
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1-Piperidine Propionic Acid Protects from Septic Shock Through Protease Receptor 2 Inhibition.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11662, doi. 10.3390/ijms252111662
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Beyond Anticoagulation: A Comprehensive Review of Non-Vitamin K Oral Anticoagulants (NOACs) in Inflammation and Protease-Activated Receptor Signaling.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8727, doi. 10.3390/ijms25168727
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New Target(s) for RNF43 Regulation: Implications for Therapeutic Strategies.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8083, doi. 10.3390/ijms25158083
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Characterization of Biomarkers of Thrombo-Inflammation in Patients with First-Diagnosed Atrial Fibrillation.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 4109, doi. 10.3390/ijms25074109
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Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1255, doi. 10.3390/ijms25021255
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Involvement of PAR-2 in the Induction of Cell-Specific Matrix Metalloproteinase-2 by Activated Protein C in Cutaneous Wound Healing.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 370, doi. 10.3390/ijms25010370
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Single-Nucleotide Polymorphisms of the PAR2 and IL-17A Genes Are Significantly Associated with Chronic Pain.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17627, doi. 10.3390/ijms242417627
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Synergistic Interaction of 5-HT 1B and 5-HT 2B Receptors in Cytoplasmic Ca 2+ Regulation in Human Umbilical Vein Endothelial Cells: Possible Involvement in Pathologies.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13833, doi. 10.3390/ijms241813833
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Species Differences in Platelet Protease-Activated Receptors.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 8298, doi. 10.3390/ijms24098298
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Involvement of Mast-Cell-Tryptase- and Protease-Activated Receptor 2—Mediated Signaling and Urothelial Barrier Dysfunction with Reduced Uroplakin II Expression in Bladder Hyperactivity Induced by Chronic Bladder Ischemia in the Rat.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3982, doi. 10.3390/ijms24043982
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PARIN5, a Novel Thrombin Receptor Antagonist Modulates a Streptozotocin Mice Model for Diabetic Encephalopathy.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2021, doi. 10.3390/ijms24032021
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Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14425, doi. 10.3390/ijms232214425
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Berbamine Reduces Chloroquine-Induced Itch in Mice through Inhibition of MrgprX1.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14321, doi. 10.3390/ijms232214321
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Aspirin Inhibits the Inflammatory Response of Protease-Activated Receptor 1 in Pregnancy Neutrophils: Implications for Treating Women with Preeclampsia.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13218, doi. 10.3390/ijms232113218
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GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810631
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LPS-Induced Coagulation and Neuronal Damage in a Mice Model Is Attenuated by Enoxaparin.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 18, p. N.PAG, doi. 10.3390/ijms231810472
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PAR-Induced Harnessing of EZH2 to β-Catenin: Implications for Colorectal Cancer.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8758, doi. 10.3390/ijms23158758
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Protease-Activated Receptor 1 in Human Carotid Atheroma Is Significantly Related to Iron Metabolism, Plaque Vulnerability, and the Patient's Age.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6363, doi. 10.3390/ijms23126363
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Gene Expression of Pregnancy Neutrophils Differs for Protease versus Lipopolysaccharide Stimulation.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4924, doi. 10.3390/ijms23094924
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Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphorylation.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3746, doi. 10.3390/ijms23073746
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Protease Activated Receptors: A Pathway to Boosting Mesenchymal Stromal Cell Therapeutic Efficacy in Acute Respiratory Distress Syndrome?
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1277, doi. 10.3390/ijms23031277
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