Works matching DE "MILTEFOSINE"

Results: 90

Treatment of Leishmania infantum Infections in Dogs.

Published in:

Microorganisms, 2025, v. 13, n. 5, p. 1018, doi. 10.3390/microorganisms13051018

By:

Kaempfle, Melanie;
Hartmann, Katrin;
Bergmann, Michèle

Publication type:

Article

Multi‐Step Synthesis of Miltefosine: Integration of Flow Chemistry with Continuous Mechanochemistry.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 70, p. 17695, doi. 10.1002/chem.202103499

By:

Patil, Niteen B.;
Atapalkar, Ranjit S.;
Chavan, Subhash P.;
Kulkarni, Amol A.

Publication type:

Article

Balamuthia mandrillaris Granulomatous Amoebic Encephalitis: The First African Experience.

Published in:

Journal of the Pediatric Infectious Diseases Society, 2022, v. 11, n. 12, p. 578, doi. 10.1093/jpids/piac096

By:

Tootla, Hafsah D;
Eley, Brian S;
Enslin, Johannes M N;
Frean, John A;
Hlela, Carol;
Kilborn, Tracy N;
Moodley, Bhavani;
Peer, Shazia;
Singh, Shivani;
Nuttall, James J C

Publication type:

Article

Understanding the characteristics of phytofabricated silver nanoparticles and their leishmanicidal potential against Indian strain of Leishmania donovani.

Published in:

Applied Nanoscience, 2023, v. 13, n. 8, p. 5729, doi. 10.1007/s13204-023-02813-6

By:

Roy Chowdhury, Dibyapriya;
Pramanik, Pijush Kanti;
Ghosh, Priyanka;
Devgupta, Pujayita;
Chakraborti, Tapati

Publication type:

Article

Resolution of Keratitis with Adjunctive Use of Oral Miltefosine.

Published in:

2021

By:

Avdagic, Ema;
Chew, Hall F.;
Veldman, Peter;
Tu, Elmer Y.;
Jafri, Mansab;
Doshi, Rutvi;
Boggild, Andrea K.;
Reidy, James J.;
Farooq, Asim V.

Publication type:

journal article

Disseminated Leishmaniasis, a Severe Form of Leishmania braziliensis Infection.

Published in:

Emerging Infectious Diseases, 2024, v. 30, n. 8, p. 510, doi. 10.3201/eid3003.230786

By:

Machado, Paulo R. L.;
Lago, Alexsandro;
Cardoso, Thiago M.;
Magalhaes, Andréa;
Carvalho, Lucas P.;
Lago, Tainã;
Carvalho, Augusto M.;
Costa, Rúbia;
Carvalho, Edgar M.

Publication type:

Article

A patient with a resistant case of centrofacial erythema.

Published in:

Clinical & Experimental Dermatology, 2025, v. 50, n. 3, p. 690, doi. 10.1093/ced/llae440

By:

Banner, Alexandra;
Dixon, Richard;
Woodrow, Sarah

Publication type:

Article

Monitoring Cutaneous Leishmaniasis Lesions in Mice Undergoing Topical Miltefosine Treatment.

Published in:

Scientia Pharmaceutica, 2023, v. 91, n. 4, p. 54, doi. 10.3390/scipharm91040054

By:

Neira, Laura Fernanda;
Mantilla, Julio Cesar;
Escobar, Patricia

Publication type:

Article

Increased Leishmania infantum resistance to miltefosine and amphotericin B after treatment of a dog with miltefosine and allopurinol.

Published in:

Parasites & Vectors, 2021, v. 14, p. 1, doi. 10.1186/s13071-021-05100-x

By:

Gonçalves, Gustavo;
Campos, Monique Paiva;
Gonçalves, Alessandra Silva;
Medeiros, Lia Carolina Soares;
Figueiredo, Fabiano Borges

Publication type:

Article

Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility.

Published in:

Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-021-04838-8

By:

Santi, Ana Maria Murta;
Silva, Paula Alves;
Santos, Isabella Fernandes Martins;
Murta, Silvane Maria Fonseca

Publication type:

Article

A randomized, open-label study to evaluate the efficacy and safety of liposomal amphotericin B (AmBisome) versus miltefosine in patients with post-kala-azar dermal leishmaniasis.

Published in:

2021

By:

Pandey, Krishna;
Pal, Biplab;
Siddiqui, Niyamat Ali;
Lal, Chandra Shekhar;
Ali, Vahab;
Bimal, Sanjiva;
Kumar, Ashish;
Verma, Neena;
Rabi Das, Vidya Nand;
Singh, Shubhankar Kumar;
Topno, Roshan Kamal;
Das, Pradeep;
Pandey, Krishna;
Das, Vidya Nand Rabi

Publication type:

journal article

Effect of Clindamycin on Intestinal Microbiome and Miltefosine Pharmacology in Hamsters Infected with Leishmania infantum.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 2, p. 362, doi. 10.3390/antibiotics12020362

By:

Olías-Molero, Ana Isabel;
Botías, Pedro;
Cuquerella, Montserrat;
García-Cantalejo, Jesús;
Barcia, Emilia;
Torrado, Susana;
Torrado, Juan José;
Alunda, José María

Publication type:

Article

Disseminated cutaneous leishmaniasis in a kidney transplant recipient.

Published in:

2023

By:

Amiri, Rezvan;
Farrokhnia, Mehrdad;
Mousavi Mehdiabadi, Fatemeh

Publication type:

Case Study

Successful Treatment of Rapidly Evolving Cutaneous Leishmaniasis With Amphotericin B and Miltefosine in an Immigrant From Venezuela.

Published in:

2024

By:

Mullis, Danielle M;
Shegog, Evan;
Studemeister, Lucy;
Hwang, Michael

Publication type:

Case Study

Development and evaluation of miltefosine-loaded nanoemulsions on in vitro culture of Toxoplasma gondii.

Published in:

Nanomedicine Journal, 2024, v. 11, n. 2, p. 172, doi. 10.22038/NMJ.2024.75808.1842

By:

Valizadeh, Gholam Reza;
Mahboobian, Mohammad Mehdi;
Maghsoud, Amir Hossein;
Mirzaei, Fatemeh;
Haghi, Mousa Motevali;
Parvar, Faezeh Foroughi;
Fallah, Mohammad

Publication type:

Article

Progress in antileishmanial drugs: Mechanisms, challenges, and prospects.

Published in:

2025

By:

Zhang, Haoran;
Yan, Ruixi;
Liu, Yahui;
Yu, Mengtao;
He, Ziyi;
Xiao, Junfeng;
Li, Kaijie;
Liu, Gang;
Ning, Qin;
Li, Yan

Publication type:

Literature Review

Review of the Clinical Presentation, Pathology, Diagnosis, and Treatment of Leishmaniasis.

Published in:

Laboratory Medicine, 2023, v. 54, n. 4, p. 363, doi. 10.1093/labmed/lmac134

By:

Mathison, Blaine A;
Bradley, Benjamin T

Publication type:

Article

Labeling Pediatric Products: BPCA Efforts and Orphan Drug Opportunities.

Published in:

Journal of Pediatric Pharmacology & Therapeutics, 2025, v. 30, n. 2, p. 226, doi. 10.5863/1551-6776-30.2.226

By:

Hui Wei;
Burckart, Gilbert J.;
Taylor-Zapata, Perdita;
Yun Wang

Publication type:

Article

Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells.

Published in:

Clinical & Translational Medicine, 2021, v. 11, n. 11, p. 1, doi. 10.1002/ctm2.552

By:

Park, So‐Yeon;
Kim, Jee‐Heun;
Choi, Jang‐Hyun;
Lee, Choong‐Jae;
Lee, Won‐Jae;
Park, Sehoon;
Park, Zee‐Yong;
Baek, Jeong‐Heum;
Nam, Jeong‐Seok

Publication type:

Article

Antiviral Activity of Nitazoxanide and Miltefosine Against FeHV‐1 In Vitro.

Published in:

Veterinary Medicine International, 2024, v. 2024, p. 1, doi. 10.1155/2024/8849561

By:

Longobardi, Consiglia;
Ferrara, Gianmarco;
Damiano, Sara;
Florio, Salvatore;
Iovane, Giuseppe;
Pagnini, Ugo;
Montagnaro, Serena;
Ciarcia, Roberto;
Rabbani, Imtiaz

Publication type:

Article

In vitro susceptibility to miltefosine of amphotericin B-resistant Leishmania (Mundinia) martiniquensis.

Published in:

Parasitology Research, 2023, v. 122, n. 12, p. 3027, doi. 10.1007/s00436-023-07992-3

By:

Mano, Chonlada;
Kongkaew, Aphisek;
Tippawangkosol, Pongsri;
Junkum, Anuluck;
Siriyasatien, Padet;
Jariyapan, Narissara

Publication type:

Article

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2229071

By:

Hassan, Ahmed H. E.;
Bayoumi, Waleed A.;
El-Sayed, Selwan M.;
Phan, Trong-Nhat;
Kim, Yeon Ju;
Lee, Chae Hyeon;
Cho, Soo Bin;
Oh, Taegeun;
Ham, Gyeongpyo;
Mahmoud, Kazem;
No, Joo Hwan;
Lee, Yong Sup

Publication type:

Article

Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 330, doi. 10.1080/14756366.2022.2150763

By:

Mohamed, Mounir A. A.;
Kadry, Asmaa M.;
Bekhit, Salma A.;
Abourehab, Mohammed A. S.;
Amagase, Kikuko;
Ibrahim, Tamer M.;
El-Saghier, Ahmed M. M.;
Bekhit, Adnan A.

Publication type:

Article

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia—authors' response.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 4, p. 1162, doi. 10.1093/jac/dkaf059

By:

Dorlo, Thomas P C;
Chu, Wan-Yu

Publication type:

Article

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 7, p. 1547, doi. 10.1093/jac/dkae129

By:

Palić, Semra;
Chu, Wan-Yu;
Sundar, Shyam;
Mondal, Dinesh;
Das, Pradeep;
Pandey, Krishna;
Raja, Sheeraz;
Rijal, Suman;
Roseboom, Ignace C;
Hamadeh, Abdullah;
Malik, Paul R V;
Beijnen, Jos H;
Huitema, Alwin D R;
Sjögren, Erik;
Alves, Fabiana;
Dorlo, Thomas P C

Publication type:

Article

Population pharmacokinetics of a combination of miltefosine and paromomycin in Eastern African children and adults with visceral leishmaniasis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 11, p. 2702, doi. 10.1093/jac/dkad286

By:

Verrest, Luka;
Roseboom, Ignace C;
Wasunna, Monique;
Mbui, Jane;
Njenga, Simon;
Musa, Ahmed M;
Olobo, Joseph;
Mohammed, Rezika;
Ritmeijer, Koert;
Chu, Wan-Yu;
Huitema, Alwin D R;
Solomos, Alexandra;
Alves, Fabiana;
Dorlo, Thomas P C

Publication type:

Article

Relapsing leishmanial arthritis: report of a tricky localization and evidence of miltefosine diffusion in synovial fluid.

Published in:

2021

By:

Contejean, Adrien;
Ayral, Xavier;
Dorlo, Thomas P C;
Roseboom, Ignace C;
Yera, Hélène;
Gana, Inès;
Chouchana, Laurent;
Canouï, Etienne;
Buffet, Pierre;
Charlier, Caroline

Publication type:

Letter

Characterizing the non-linear pharmacokinetics of miltefosine in paediatric visceral leishmaniasis patients from Eastern Africa.

Published in:

2020

By:

Palić, Semra;
Kip, Anke E;
Beijnen, Jos H;
Mbui, Jane;
Musa, Ahmed;
Solomos, Alexandra;
Wasunna, Monique;
Olobo, Joseph;
Alves, Fabiana;
Dorlo, Thomas P C

Publication type:

journal article

Unmasking the Mechanism behind Miltefosine: Revealing the Disruption of Intracellular Ca 2+ Homeostasis as a Rational Therapeutic Target in Leishmaniasis and Chagas Disease.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 4, p. 406, doi. 10.3390/biom14040406

By:

Benaim, Gustavo;
Paniz-Mondolfi, Alberto

Publication type:

Article

The cure rate after different treatments for mucosal leishmaniasis in the Americas: A systematic review.

Published in:

PLoS Neglected Tropical Diseases, 2022, v. 16, n. 11, p. 1, doi. 10.1371/journal.pntd.0010931

By:

Carvalho, Janaína de Pina;
Silva, Sarah Nascimento;
Freire, Mariana Lourenço;
Alves, Líndicy Leidicy;
Souza, Carolina Senra Alves de;
Cota, Gláucia

Publication type:

Article

A phase II multicenter randomized study to evaluate the safety and efficacy of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World.

Published in:

PLoS Neglected Tropical Diseases, 2022, v. 16, n. 3, p. 1, doi. 10.1371/journal.pntd.0010238

By:

López, Liliana;
Alvarez, Fiorela;
Ramos, Ana Pilar;
Llanos-Cuentas, Alejandro;
Echevarria, Juan;
Vélez, Iván;
Boni, Marina;
Rode, Joelle;
Quintero, Juliana;
Jiménez, Alejandra;
Tabares, Yulied;
Méndez, Claudia;
Arana, Byron

Publication type:

Article

Miltefosine in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis in Brazil: A Randomized and Controlled Trial.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 12, p. 1, doi. 10.1371/journal.pntd.0000912

By:

Machado, Paulo R.;
Ampuero, Julia;
Guimarães, Luiz H.;
Villasboas, Leonardo;
Rocha, Ana T.;
Schriefer, Albert;
Sousa, Rosana S.;
Talhari, Anette;
Penna, Gerson;
Carvalho, Edgar M.

Publication type:

Article

Effectiveness of Miltefosine Nanoemulsion Concerning the Treatment of Acute and Chronic Toxoplasmosis: In Vivo Study.

Published in:

Iranian Journal of Parasitology, 2024, v. 19, n. 3, p. 314

By:

Valizadeh, Gholam Reza;
Mahboubian, Mohammad Mahdi;
Maghsoud, Amir Hossein;
Mirzaei, Fatemeh;
Haghi, Seyedmousa Motavalli;
Parvar, Faezeh Foroughi;
Fallah, Mohammad

Publication type:

Article

Evaluation of In Vitro Cytotoxic and Apoptotic Effects of Miltefosine on the Toxoplasma gondii RH Strain.

Published in:

Iranian Journal of Parasitology, 2024, v. 19, n. 1, p. 52

By:

Khademvatan, Shahram;
Yousefi, Elham;
Asadi, Negar;
Abasi, Esmaeil

Publication type:

Article

Clinical, histopathological and parasitological follow-up of dogs naturally infected by Leishmania infantum before and after miltefosine treatment and associated therapies.

Published in:

PLoS ONE, 2025, v. 20, n. 1, p. 1, doi. 10.1371/journal.pone.0313167

By:

Rosar, Amábilli de Souza;
Martins, Carolina Leite;
Menin, Álvaro;
Reck, Carolina;
Grisard, Edmundo Carlos;
Wagner, Glauber;
Steindel, Mário;
Stoco, Patricia Hermes;
Quaresma, Patricia Flavia

Publication type:

Article

Safety profile of miltefosine in the treatment of cutaneous leishmaniasis.

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0315710

By:

Ribeiro, Laís Raquel;
Silva, Sarah Nascimento;
Saliba, Mell Ferreira;
de Pina Carvalho, Janaína;
Cota, Gláucia

Publication type:

Article

Exploring hydrophilic 2,2-di(indol-3-yl)ethanamine derivatives against Leishmania infantum.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0301901

By:

Centanni, Alessia;
Diotallevi, Aurora;
Buffi, Gloria;
Olivieri, Diego;
Santarém, Nuno;
Lehtinen, Antti;
Yli-Kauhaluoma, Jari;
Cordeiro-da-Silva, Anabela;
Kiuru, Paula;
Lucarini, Simone;
Galluzzi, Luca

Publication type:

Article

Ophthalmic adverse effects of miltefosine in the treatment of leishmaniasis: a systematic review.

Published in:

Cutaneous & Ocular Toxicology, 2024, v. 43, n. 3, p. 190, doi. 10.1080/15569527.2024.2380311

By:

Pal, Biplab;
Atem, Tambe Daniel;
Kumari, Sweta;
Murti, Krishna;
Kumar, Rishikesh;
Pandey, Krishna;
Siddiqui, Niyamat Ali;
Dhingra, Sameer;
Chaudhary, Vaibhav

Publication type:

Article

A case report on para-kala-azar dermal leishmaniasis: an unresolved mystery.

Published in:

2023

By:

Hasan, Md. Mehedi;
Proma, Sanghita Banik;
Hossain, Md. Saddam;
Arifuzzaman, Md.;
Islam, Naylla;
Siddique, Md. Abu Bakar;
Amiruzzaman

Publication type:

Case Study

New ψ -Santonin Derivatives from Crossostephium chinense and Their Anti-Proliferative Activities against Leishmania major and Human Cancer Cells A549.

Published in:

Molecules, 2023, v. 28, n. 24, p. 8108, doi. 10.3390/molecules28248108

By:

Wang, Zhichao;
Yamano, Yoshi;
Kawakami, Susumu;
Al-Hamoud, Gadah Abdulaziz;
Sugimoto, Sachiko;
Otsuka, Hideaki;
Matsunami, Katsuyoshi

Publication type:

Article

Direct In Vitro Comparison of the Anti-Leishmanial Activity of Different Olive Oil Total Polyphenolic Fractions and Assessment of Their Combined Effects with Miltefosine.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6176, doi. 10.3390/molecules27196176

By:

Gogou, Georgia;
Koutsoni, Olga S.;
Stathopoulos, Panagiotis;
Skaltsounis, Leandros A.;
Halabalaki, Maria;
Dotsika, Eleni

Publication type:

Article

Potential Inhibitory Effect of Miltefosine against Terbinafine-Resistant Trichophyton indotineae.

Published in:

Pathogens, 2023, v. 12, n. 4, p. 606, doi. 10.3390/pathogens12040606

By:

Haghani, Iman;
Akhtari, Javad;
Yahyazadeh, Zahra;
Espahbodi, Amirreza;
Kermani, Firoozeh;
Javidnia, Javad;
Hedayati, Mohammad Taghi;
Shokohi, Tahereh;
Badali, Hamid;
Rezaei-Matehkolaei, Ali;
Aghili, Seyed Reza;
Al-Rawahi, Ahmed;
Al-Harrasi, Ahmed;
Abastabar, Mahdi;
Al-Hatmi, Abdullah M. S.

Publication type:

Article

Sporothrix spp. Biofilms Impact in the Zoonotic Transmission Route: Feline Claws Associated Biofilms, Itraconazole Tolerance, and Potential Repurposing for Miltefosine.

Published in:

Pathogens, 2022, v. 11, n. 2, p. 206, doi. 10.3390/pathogens11020206

By:

dos Santos, Giulia Maria Pires;
Borba-Santos, Luana Pereira;
Vila, Taissa;
Ferreira Gremião, Isabella Dib;
Pereira, Sandro Antonio;
De Souza, Wanderley;
Rozental, Sonia

Publication type:

Article

MILTEFOSINE (MILTEFOSINUM).

Published in:: WHO Drug Information, 2023, v. 37, n. 1, p. 08
Publication type:: Article

MILTEFOSINE CAPSULES (MILTEFOSINI CAPSULES).

Published in:: WHO Drug Information, 2023, v. 37, n. 1, p. 01
Publication type:: Article

Assessing Dose-Exposure–Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach.

Published in:

Pharmaceutical Research, 2023, v. 40, n. 12, p. 2983, doi. 10.1007/s11095-023-03610-0

By:

Madu, Shadrack J.;
Wang, Ke;
Chirumamilla, Siri Kalyan;
Turner, David B.;
Steel, Patrick G.;
Li, Mingzhong

Publication type:

Article

Leishmaniasis.

Published in:

Indian Journal of Critical Care Medicine, 2021, v. 25, n. S2, p. S166, doi. 10.5005/jp-journals-10071-23844

By:

Daga, Mradul K.;
Rohatgi, Ishan;
Mishra, Rashmi

Publication type:

Article

In Vitro Evaluation of the Combinatorial Effect of Naringenin and Miltefosine against Leishmania amazonensis.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 8, p. 1014, doi. 10.3390/ph17081014

By:

Lessa, Vinícius Lopes;
Gonçalves, Gustavo;
Santos, Beatriz;
Cavalari, Victoria Cruz;
da Costa Vieira, Rafael Felipe;
Figueiredo, Fabiano Borges

Publication type:

Article

Dual Antitubercular and Antileishmanial Profiles of Quinoxaline Di- N -Oxides Containing an Amino Acidic Side Chain.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 487, doi. 10.3390/ph17040487

By:

González, Juan F.;
Dea-Ayuela, María-Auxiliadora;
Huck, Lena;
Orduña, José María;
Bolás-Fernández, Francisco;
de la Cuesta, Elena;
Haseen, Nazia;
Mohammed, Ashraf Ali;
Menéndez, J. Carlos

Publication type:

Article

Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 7, p. 1, doi. 10.1371/journal.pntd.0009622

By:

Bulté, Dimitri;
Van Bockstal, Lieselotte;
Dirkx, Laura;
Van den Kerkhof, Magali;
De Trez, Carl;
Timmermans, Jean-Pierre;
Hendrickx, Sarah;
Maes, Louis;
Caljon, Guy

Publication type:

Article