Works matching DE "TUMOR microenvironment"

Results: 5000

Feasibility analysis and development trend of nanomaterials for the treatment of pancreatic cancer.

Published in:

Discover Nano, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s11671-025-04259-x

By:

Zhu, Jingyao;
Li, Yue;
Li, Xiaoqing;
Wang, Yong;
Liu, Qixiang;
Yang, Yang;
Guan, HongJian

Publication type:

Article

Development of a machine learning-based predictive risk model combining fatty acid metabolism and ferroptosis for immunotherapy response and prognosis in prostate cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02484-5

By:

Wang, Zhenwei;
Dai, Zhihong;
Gao, Yuren;
Zhao, Zhongxiang;
Li, Zhen;
Wang, Liang;
Gao, Xiang;
Qiu, Qiuqiu;
Qiu, Xiaofu;
Liu, Zhiyu

Publication type:

Article

Construction of a novel CD8T cell-related index for predicting clinical outcomes and immune landscape in ovarian cancer by combined single-cell and RNA-sequencing analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02582-4

By:

Zhang, Yu;
Wan, Peng;
Wang, Liangliang;
Ren, Ruiping

Publication type:

Article

Role of M2 macrophage-derived exosomes in cancer drug resistance via noncoding RNAs.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02195-x

By:

Hu, Xiaopeng;
Li, Yanhua;
Wang, Xisheng;
Xue, Xingkui

Publication type:

Article

Identification of the role of MED6 in the development and prognosis of lung adenocarcinoma based on multi-omics profiling.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2362, doi. 10.7150/jca.110981

By:

Changqing Yang;
Ding Cheng;
Shuo Wang;
Baichuan Wang;
Yingxi Li;
Guixin Wang;
Xingkai Wang;
Cangchang Shi;
Yao Tian;
Keyun Zhu;
Jing Feng

Publication type:

Article

Effects of Exercise Intensity and Time on Efficacy of Paclitaxel and Doxorubicin and Immune Microenvironment in the 4T1 Breast Cancer Model.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2298, doi. 10.7150/jca.105352

By:

Liang Zhou;
Yonghong Yang;
Xiang Luo;
Xinling Gan;
Chengqi He;
Yong Xia;
Siyi Zhu

Publication type:

Article

Nano-strategies for Targeting Tumor-Associated Macrophages in Cancer immunotherapy.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2261, doi. 10.7150/jca.108194

By:

Qian Li;
Jingwei Xu;
Runjia Hua;
Hanye Xu;
Yongyou Wu;
Xiaju Cheng

Publication type:

Article

Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02883-6

By:

Zhao, Fu;
Teng, Xu-Fei;
Zhang, Jing;
Li, Shi-Wei;
Wang, Lei-Ming;
Zhao, Han-Guang;
Zhang, Shun;
Zhao, Chi;
Li, Peng;
Zhao, Xiao-Bin;
Song, Shu-Hui;
Liu, Pi-Nan

Publication type:

Article

Tumour-infiltrating immune cells as a novel prognostic model for bladder cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02292-x

By:

Liu, Can;
Liao, Chaoyu;
Sun, Bishao;
Guo, Zhen;
Chen, Sihao;
Liu, Shixue;
Yuan, Xiaoyu;
Huang, Zeyu;
Liu, Jingui;
Deng, Min;
Wang, Kui;
Wu, Ruixin;
Zhao, Jiang;
Dong, Xingyou

Publication type:

Article

Aberrant expression of CNTRL was associated with poor prognosis, immune response and progression in glioma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02531-1

By:

Mei, Xiaoping;
Qin, Deyuan;
Zou, Min;
Teng, Hongli;
Zhai, Yang

Publication type:

Article

Global research trends in tumor-associated macrophage studies: a bibliometric analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02473-8

By:

Luan, Aina;
Zhang, Yipeng;
Yang, Lu;
Zhao, Guojing;
Yang, Xin

Publication type:

Article

An Overview of Predictive Biomarkers and Detection Approaches for Immunotherapy Response in GI Malignancies.

Published in:

Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 5, p. 1059, doi. 10.1111/jgh.16930

By:

Chai, Xinyu;
Zhang, Yiwen;
Shi, Zhihui;
Yang, Ruiling;
Liu, Xumin;
Zhou, Yueting;
Li, Caiyang;
Li, Zhenhui

Publication type:

Article

Single‐Cell Transcriptomic Analysis Reveals an Aggressive Basal‐Like Tumor Cell Subpopulation Associated With Poor Prognosis in Intrahepatic Cholangiocarcinoma.

Published in:

Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 5, p. 1263, doi. 10.1111/jgh.16915

By:

Liao, Changyi;
Zhang, Yuting;
Yang, Jing;
Wang, Shuo;
Li, Zhijuan;
Chen, Shuling;
Xie, Yubin;
Xu, Lixia;
Peng, Sui;
Zeng, Xuezhen;
Kuang, Ming;
Xiang, Bangde;
Sun, Kaiyu;
Zhao, Xiao

Publication type:

Article

Neuro–astrocytic network in breast cancer brain metastases: Adaptive mechanisms and novel therapeutic targets.

Published in:

International Journal of Cancer, 2025, v. 157, n. 1, p. 18, doi. 10.1002/ijc.35421

By:

Huang, Tao;
Wu, Duolu;
Jiang, Lu;
Wu, Zepei;
Zhao, Yubo;
Tang, Fansong;
Mou, Zhenglin;
Pan, Caihou;
Liu, Yi;
Tong, Aiping;
Zhou, Liangxue;
Xu, Jianguo;
Wang, Yuelong

Publication type:

Article

Efficacy and optimal duration of maintenance immunotherapy following systemic chemoimmunotherapy and locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: A multicenter retrospective cohort study.

Published in:

International Journal of Cancer, 2025, v. 157, n. 1, p. 139, doi. 10.1002/ijc.35382

By:

Hu, Yujun;
Lu, Tianzhu;
Zhang, Hao;
Chen, Bijuan;
Pan, Jianji;
Li, Jingao;
Gong, Xiaochang;
Li, Hui;
Huang, Yingying;
Lu, Nian;
Liang, Yujing;
Ke, Liangru;
Xie, Chuanmiao

Publication type:

Article

Targeting fatty acid oxidation: A potential strategy for treating gastrointestinal tumors.

Published in:

International Journal of Cancer, 2025, v. 157, n. 1, p. 7, doi. 10.1002/ijc.35380

By:

Zheng, Yingsong;
Jiang, Zhengchen;
Yuan, Li;
Cheng, Xiangdong;
He, Weiyang;
Chen, Xiaodong

Publication type:

Article

Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03263-0

By:

Cheng, Qinpei;
Zuo, Xueying;
Wang, Zimu;
Lu, Wanjun;
Jiang, Yuxin;
Liu, Jiaxin;
Li, Xinying;
Xu, Qiuli;
Zhu, Suhua;
Liu, Xin;
Song, Yong;
Zhan, Ping;
Lv, Tangfeng

Publication type:

Article

Thioredoxin: a key factor in cold tumor formation and a promising biomarker for immunotherapy resistance in NSCLC.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03259-w

By:

Hu, Jiayi;
Abulimiti, Yilimunuer;
Wang, Haiyang;
Yang, Dianyu;
Wang, Xu;
Wang, Yang;
Ji, Ping

Publication type:

Article

Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures.

Published in:

Journal of Tissue Engineering, 2025, p. 1, doi. 10.1177/20417314251326668

By:

Olvera-Valencia, Mercedes;
Garcia-Castillo, Verónica;
Ramos-Payan, Rosalío;
Aguilar-Medina, Maribel;
Trujano-Camacho, Samuel;
López-Saavedra, Alejandro;
Marchat, Laurence A.;
López-Camarillo, Cesar;
Sumagin, Ronen;
Pérez-Yepez, Eloy;
Pérez-Plasencia, Carlos

Publication type:

Article

Single-cell and bulk transcriptome sequencing identifies circadian rhythm disruption and cluster-specific clinical insights in colorectal tumorigenesis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02521-3

By:

Liu, Chen;
Liu, Jingyang;
Shao, Jing;
Zhao, Xiaoman;
Xie, Lin;
Shang, Mengyao;
Li, Ying;
Li, Weiming

Publication type:

Article

Evaluating the safety and feasibility of allogeneic NK cell infusion in high-risk lymphoma patients post-autologous stem cell transplantation.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02489-0

By:

Tavakoli, Shirin;
Samareh-Salavatipour, Maryam;
Mardi, Amirhossein;
Salehi-Shadkami, Hossein;
Vaezi, Mohammad;
Barkhordar, Maryam;
Ahmadvand, Mohammad

Publication type:

Article

Multi-dimensional characterization of cellular states reveals clinically relevant immunological subtypes and therapeutic vulnerabilities in ovarian cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06521-3

By:

Zhang, Can;
Li, Si;
Guo, Jiyu;
Pan, Tao;
Zhang, Ya;
Gao, Yueying;
Pan, Jiwei;
Liu, Meng;
Yang, Qingyi;
Yu, Jinyang;
Xu, Juan;
Li, Yongsheng;
Li, Xia

Publication type:

Article

Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1500570

By:

Jennings, Victoria A.;
Rumbold-Hall, Reah;
Migneco, Gemma;
Barr, Tyler;
Reilly, Katrina;
Ingram, Nicola;
St Hilare, Isabelle;
Heaton, Samuel;
Alzamel, Noura;
Jackson, David;
Ralph, Christy;
Banerjee, Susan;
McNeish, Iain;
Bell, John C.;
Melcher, Alan A.;
Ilkow, Carolina;
Cook, Graham P.;
Errington-Mais, Fiona

Publication type:

Article

Breakthroughs and challenges of organoid models for assessing cancer immunotherapy: a cutting-edge tool for advancing personalised treatments.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02505-w

By:

Wang, Qian;
Yuan, Fangwei;
Zuo, Xianglin;
Li, Ming

Publication type:

Article

PAQR5 drives the malignant progression and shapes the immunosuppressive microenvironment of hepatocellular carcinoma by activating the NF-κB signaling.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00785-z

By:

Yang, Ruida;
Wang, Huanhuan;
Wu, Cong;
Shi, Yu;
Li, Hanqi;
Bao, Xinyue;
Yang, Yuqian;
Han, Shaoshan;
Yang, Xue;
Tao, Jie;
Sun, Hao;
Wu, Shaobo;
Sun, Liankang

Publication type:

Article

A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer.

Published in:

Journal of Pathology, 2025, v. 266, n. 2, p. 192, doi. 10.1002/path.6415

By:

Huang, Zhihao;
Mandelkow, Tim;
Debatin, Nicolaus F;
Lurati, Magalie C J;
Ebner, Julia;
Raedler, Jonas B;
Bady, Elena;
Müller, Jan H;
Simon, Ronald;
Vettorazzi, Eik;
Menz, Anne;
Möller, Katharina;
Gorbokon, Natalia;
Sauter, Guido;
Lennartz, Maximilian;
Luebke, Andreas M;
Höflmayer, Doris;
Krech, Till;
Lebok, Patrick;
Fraune, Christoph

Publication type:

Article

M2 macrophage-derived exosomes promote cell proliferation, migration and EMT of non-small cell lung cancer by secreting miR-155-5p.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 5, p. 3019, doi. 10.1007/s11010-024-05161-3

By:

Fang, Hua;
Chi, Xiaowen;
Wang, Mengyao;
Liu, Jing;
Sun, Meiqi;
Zhang, Jiashu;
Zhang, Wei

Publication type:

Article

Optimal in vitro models as a basis for understanding and more effective treatment of infantile haemangiomas.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 5, p. 791, doi. 10.1093/bjd/ljae505

By:

Bašković, Marko

Publication type:

Article

Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer.

Published in:

Breast Cancer: Targets & Therapy, 2025, v. 17, p. 211, doi. 10.2147/BCTT.S493085

By:

Oner, Gizem;
Praet, Marleen Marguerite;
Stoop, Hans;
Devi, Gayathri R;
Canturk, Nuh Zafer;
Altintas, Sevilay;
Van Berckelaer, Christophe;
Berneman, Zwi;
Tjalma, Wiebren;
Koljenovic, Senada;
van Dam, Peter A

Publication type:

Article

The association between tumor-stromal collagen features and the clinical outcomes of patients with breast cancer: a systematic review.

Published in:

Breast Cancer Research, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s13058-025-02017-6

By:

Heydari, Samane;
Tajik, Fatemeh;
Safaei, Sadegh;
Kamani, Fereshteh;
Karami, Babak;
Dorafshan, Shima;
Madjd, Zahra;
Ghods, Roya

Publication type:

Article

A method for screening functional anti-Treg antibodies using a Treg-like cell line.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 4, p. 1, doi. 10.1093/jleuko/qiae257

By:

Pfeffer, Kirsten;
Ho, Thai H;
Ruiz, Yvette;
Lake, Douglas F

Publication type:

Article

The progress and challenges in modeling colorectal cancer and the impact on novel drug discovery.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 5, p. 565, doi. 10.1080/17460441.2024.2404238

By:

Teixeira, Natália;
Baião, Ana;
Dias, Sofia;
Sarmento, Bruno

Publication type:

Article

Acoustically activated nanoplatforms achieve tumor regression by exacerbating tumor hypoxia.

Published in:

Journal of Cancer Research & Therapeutics, 2025, v. 21, n. 2, p. 371, doi. 10.4103/jcrt.jcrt_1838_24

By:

Ling, Caixia;
Ma, Shanshan;
Zhang, Mengqi;
Su, Danke;
Liang, Zixuan

Publication type:

Article

Oral and intestinal flora translocation and tumor development.

Published in:

Journal of Cancer Research & Therapeutics, 2025, v. 21, n. 2, p. 323, doi. 10.4103/jcrt.jcrt_50_24

By:

Ye, Zhiyuan;
Gao, Linglin;
Guo, Zhi;
Wang, Qiang

Publication type:

Article

Exploring tumor-associated macrophages in glioblastoma: from diversity to therapy.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00920-x

By:

Zhao, Wenwen;
Zhang, Zhi;
Xie, Mingyuan;
Ding, Feng;
Zheng, Xiangrong;
Sun, Shicheng;
Du, Jianyang

Publication type:

Article

IL-33/ST2 signalling promotes tumor growth by regulating polarization of alternatively activated macrophages.

Published in:

Cancer Biology & Medicine, 2025, v. 22, n. 4, p. 376, doi. 10.20892/j.issn.2095-3941.2024.0483

By:

Liping Liu;
Haoge Luo;
Yingdong Xie;
Ying Wang;
Shiying Ren;
Haiyang Sun;
Dong Li

Publication type:

Article

Editorial: Innovative multidisciplinary insights into the gut-liver axis and cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1588708

By:

Gundamaraju, Rohit;
Goh, Bey Hing;
Singla, Rajeev K.

Publication type:

Article

Corrigendum: Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs.

Published in:

2025

By:

Shao, Shengwen;
Miao, Huilai;
Ma, Wenxue

Publication type:

Correction Notice

Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment.

Published in:

2025

By:

Jennings, Victoria A.;
Rumbold-Hall, Reah;
Migneco, Gemma;
Barr, Tyler;
Reilly, Katrina;
Ingram, Nicola;
Hilare, Isabelle St;
Heaton, Samuel;
Alzamel, Noura;
Jackson, David;
Ralph, Christy;
Banerjee, Susan;
McNeish, Iain;
Bell, John C.;
Melcher, Alan A.;
Ilkow, Carolina;
Cook, Graham P.;
Errington-Mais, Fiona

Publication type:

Correction Notice

From ex vivo to in vitro models: towards a novel approach to investigate the efficacy of immunotherapies on exhausted Vγ9Vδ2 T cells?

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1556982

By:

Chauvet, Morgane;
Bourges, Dorothée;
Scotet, Emmanuel

Publication type:

Article

The role of macrophage polarization in ovarian cancer: from molecular mechanism to therapeutic potentials.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1543096

By:

Xu, Chenchen;
Chen, Jiyu;
Tan, Mi;
Tan, Qingqing

Publication type:

Article

Tissue-resident immune cells in cervical cancer: emerging roles and therapeutic implications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1541950

By:

Li, Xidie;
Deng, Juan;
Liu, Xiaoping;
Zhou, Yan;
Bi, Tingting;
Chen, Jingjing;
Wang, Jinjin

Publication type:

Article

Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2023.1295684

By:

Shao, Shengwen;
Miao, Huilai;
Ma, Wenxue

Publication type:

Article

Tumor Immunotherapy Targeting B7-H3: From Mechanisms to Clinical Applications.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 291, doi. 10.2147/ITT.S507522

By:

Guo, Yining;
Wang, Xudong;
Zhang, Chen;
Chen, Weiwu;
Fu, Yutian;
Yu, Yanlan;
Chen, Yicheng;
Shao, Tiejuan;
Zhang, Jie;
Ding, Guoqing

Publication type:

Article

Harnessing engineered extracellular vesicles for enhanced therapeutic efficacy: advancements in cancer immunotherapy.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03403-w

By:

Gong, Zheng;
Cheng, Cheng;
Sun, Chaonan;
Cheng, Xiaoli

Publication type:

Article

Development of a hypoxia-responsive macrophage prognostic model using single-cell and bulk RNA sequencing in pancreatic cancer.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322618

By:

Ge, Heming;
Wolters-Eisfeld, Gerrit;
Hackert, Thilo;
Li, Yuqiang;
Güngör, Cenap

Publication type:

Article

MYC networks associate with decreased CD8 T-cell presence in diffuse large B-cell lymphoma and may be addressed by the synergistic combination of AZD4573 and Selinexor – a preliminary analysis.

Published in:

Annals of Hematology, 2025, v. 104, n. 4, p. 2403, doi. 10.1007/s00277-025-06298-x

By:

Rutz, Alison C.;
Weber, Kennedee S.;
Forberg, Aidan L.;
Nik, Adam;
Unrau, Jordan;
Hemmen, Ainslee J.;
Minicozzi, Michael;
Hartert, Keenan T.

Publication type:

Article

The therapeutic effect of thermo-sensitive hydrogel loaded with recombinant mycobacterium smegmatis expressing exogenous IL-15 in abdominal metastasis.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06454-x

By:

Wang, Qi;
Mei, Yi;
Rao, Wenmei;
Hong, Sen;
Chen, Aoxing;
Yang, Yang;
Liu, Qin

Publication type:

Article

Exosome-mediated ferroptosis in the tumor microenvironment: from molecular mechanisms to clinical application.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02484-y

By:

Liu, Na;
Wu, Tianqing;
Han, Guohu;
Chen, Minbin

Publication type:

Article

Identification and characterization of tertiary lymphoid structures in brain metastases.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02007-x

By:

Mughal, Sadaf S.;
Reiss, Yvonne;
Felsberg, Jörg;
Meyer, Lasse;
Macas, Jadranka;
Schlue, Silja;
Starzetz, Tatjana;
Köhrer, Karl;
Fehm, Tanja;
Müller, Volkmar;
Lamszus, Katrin;
Schadendorf, Dirk;
Helfrich, Iris;
Wikman, Harriet;
Berghoff, Anna;
Brors, Benedikt;
Plate, Karl H.;
Reifenberger, Guido

Publication type:

Article