Works matching DE "HYPOXIA-inducible factor 1"

Results: 1652

Overexpression of MAFG-AS1 in ovarian cancer promotes glucose metabolism reprogramming and malignant biological behavior of ovarian cancer cells by regulating HIF-1α.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02429-y

By:

Jia, Liu;
Yu, Fei

Publication type:

Article

Hypoxia and HIF-1 inhibition enhance lentiviral transduction efficiency: a novel strategy for gene delivery optimization.

Published in:

BMC Biotechnology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12896-025-00969-3

By:

Huo, Qianyu;
Wang, Wentian;
Dai, Jiawen;
Yuan, Xu;
Yu, Dandan;
Xu, Bingqi;
Chi, Ying;
Li, Huiyuan;
Pei, Xiao Lei;
Zhu, Guoqing;
Zhang, Lei

Publication type:

Article

Kaempferol promotes apoptosis and inhibits proliferation and migration by suppressing HIF-1α/VEGF and Wnt/β-catenin activation under hypoxic condition in colon cancer.

Published in:

Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-00992-0

By:

Haroon, Muhammad;
Kang, Sun Chul

Publication type:

Article

HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001665

By:

Eckle, Tobias;
Brodsky, Kelley;
Bonney, Megan;
Packard, Thomas;
Han, Jun;
Borchers, Christoph H.;
Mariani, Thomas J.;
Kominsky, Douglas J.;
Mittelbronn, Michel;
Eltzschig, Holger K.

Publication type:

Article

Identification of Malate Dehydrogenase 2 as a Target Protein of the HIF-1 Inhibitor LW6 using Chemical Probes.

Published in:

Angewandte Chemie, 2013, v. 125, n. 39, p. 10476, doi. 10.1002/ange.201304987

By:

Lee, Kyeong;
Ban, Hyun Seung;
Naik, Ravi;
Hong, Ye Seul;
Son, Seohyun;
Kim, Bo-Kyung;
Xia, Yan;
Song, Kyung Bin;
Lee, Hong-Sub;
Won, Misun

Publication type:

Article

Hypoxia enhances the protective effects of placenta-derived mesenchymal stem cells against scar formation through hypoxia-inducible factor-1α.

Published in:

Biotechnology Letters, 2016, v. 38, n. 6, p. 931, doi. 10.1007/s10529-016-2067-6

By:

Du, Lili;
Lv, Runxiao;
Yang, Xiaoyi;
Cheng, Shaohang;
Xu, Jing;
Ma, Tingxian

Publication type:

Article

Human adipose-derived stem cells modified by HIF-1α accelerate the recovery of cisplatin-induced acute renal injury in vitro.

Published in:

Biotechnology Letters, 2014, v. 36, n. 3, p. 667, doi. 10.1007/s10529-013-1389-x

By:

Wang, WeiWei;
Wang, Wei;
Jiang, Yan;
Li, Zezheng;
Cheng, Jin;
Liu, Nanmei;
Han, GuoFeng;
Lu, Shi;
Zhang, JinYuan

Publication type:

Article

Propranolol inhibits the activity of PI3K, AKT, and HIF-1α in infantile hemangiomas.

Published in:

2018

By:

Lin, Zhenying;
Wang, Luanhong;
Huang, Guang;
Wang, Wenyan;
Lin, Han

Publication type:

journal article

A Genetic Association Study of a Specific Gene and Severe Form of Resorption in the Edentulous Mandible in the Egyptian Population.

Published in:

Journal of Prosthodontics (John Wiley & Sons, Inc.), 2019, v. 28, n. 4, p. 409, doi. 10.1111/jopr.13045

By:

Emam, Samar M.;
Amin, Asmaa K.;
Issa, Noha M.;
El‐Attar, Mohamed S.

Publication type:

Article

Expression profiles of pro-inflammatory and pro-apoptotic mediators in secondary tethered cord syndrome after myelomeningocele repair surgery.

Published in:

Child's Nervous System, 2019, v. 35, n. 2, p. 315, doi. 10.1007/s00381-018-3984-6

By:

Cohrs, Gesa;
Drucks, Bea;
Sürie, Jan-Philip;
Vokuhl, Christian;
Synowitz, Michael;
Held-Feindt, Janka;
Knerlich-Lukoschus, Friederike

Publication type:

Article

Modes of carbon dioxide delivery during laparoscopy generate distinct differences in peritoneal damage and hypoxia in a porcine model.

Published in:

2020

By:

Sampurno, Shienny;
Chittleborough, Timothy J.;
Carpinteri, Sandra;
Hiller, Jonathan;
Heriot, Alexander;
Lynch, Andrew Craig;
Ramsay, Robert George

Publication type:

journal article

The Role of NO Synthase in the Infarct-Limiting Effect of Urgent and Chronic Adaptation to Normobaric Hypoxia.

Published in:

Bulletin of Experimental Biology & Medicine, 2023, v. 174, n. 3, p. 304, doi. 10.1007/s10517-023-05696-3

By:

Naryzhnaya, N. V.;
Sementsov, A. S.;
Maslov, L. N.;
Derkachev, I. A.

Publication type:

Article

Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 165, n. 6, p. 781, doi. 10.1007/s10517-018-4264-x

By:

Dzhalilova, D. S.;
Diatroptov, M. E.;
Tsvetkov, I. S.;
Makarova, O. V.;
Kuznetsov, S. L.

Publication type:

Article

HIF-1 ACTIVATION AND INFLAMMATORY RESPONSES TO HYPOXIA.

Published in:

International Journal of Aviation, Aeronautics & Aerospace, 2023, v. 10, n. 2, p. 1, doi. 10.58940/2374-6793.1798

By:

shaharuddin, Shazreen;
Nik Abd Rahman, Nik Mohd Afizan;
Masarudin, Mas Jaffri;
Alamassi, Mohammedarfat N.

Publication type:

Article

Chronic neuronal activation leads to elevated lactate dehydrogenase A through the AMP-activated protein kinase/hypoxia-inducible factor-1α hypoxia pathway.

Published in:

Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcac298

By:

Ksendzovsky, Alexander;
Bachani, Muznabanu;
Altshuler, Marcelle;
Walbridge, Stuart;
Mortazavi, Armin;
Moyer, Mitchell;
Chixiang Chen;
Fayed, Islam;
Steiner, Joseph;
Edwards, Nancy;
Inati, Sara K.;
Jahanipour, Jahandar;
Maric, Dragan;
Heiss, John D.;
Kapur, Jaideep;
Zaghloul, Kareem A.

Publication type:

Article

Investigating Mitochondrial Metabolism in Contracting HL-1 Cardiomyocytes Following Hypoxia and Pharmacological HIF Activation Identifies HIF-Dependent and Independent Mechanisms of Regulation.

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2014, v. 19, n. 6, p. 574, doi. 10.1177/1074248414524480

By:

Ambrose, Lucy J. A.;
Abd-Jamil, Amira H.;
Gomes, Renata S. M.;
Carter, Emma E.;
Carr, Carolyn A.;
Clarke, Kieran;
Heather, Lisa C.

Publication type:

Article

Hypoxic preconditioning accelerates the healing of ischemic intestinal injury by activating HIF-1α/PPARα pathway-mediated fatty acid oxidation.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01937-0

By:

Li, Linxia;
Liu, Yanqi;
Zhi, Na;
Ji, Yaoxuan;
Xu, Jialing;
Mao, Guoyun;
Wang, Yazhou;
Ma, Jin;
Wang, Yunying

Publication type:

Article

Exogenous Ang-(1-7) inhibits autophagy via HIF-1α/THBS1/BECN1 axis to alleviate chronic intermittent hypoxia-enhanced airway remodelling of asthma.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01662-0

By:

Zhou, Jian Ping;
Wang, Yi;
Li, Shi Qi;
Zhang, Jia Qi;
Lin, Ying Ni;
Sun, Xian Wen;
Zhou, Li Na;
Zhang, Liu;
Lu, Fang Ying;
Ding, Yong Jie;
Li, Qing Yun

Publication type:

Article

Expression of vascular endothelial growth factor and hypoxia-inducible factor-1 alpha during the periovulatory period in goats.

Published in:

Turkish Journal of Veterinary & Animal Sciences, 2014, v. 38, n. 6, p. 699, doi. 10.3906/vet-1404-54

By:

Chainarong NAVANUKRAW;
Jiratti THAMMASIRI;
Tossapol MOONMANEE;
Jaruk NATTHAKORNKUL

Publication type:

Article

Could HIF-1α be a novel biomarker for the clinical course and treatment of pulmonary embolism?

Published in:

Turkish Journal of Medical Sciences, 2020, v. 50, n. 4, p. 963, doi. 10.3906/sag-1908-93

By:

KERGET, Buğra;
AFŞİN, Dursun Erol;
AKSAKAL, Alperen;
AŞKIN, Seda;
ARAZ, Ömer

Publication type:

Article

Life-stage dependent Histological Characterization of Liver HIF-1α Expression in the Indonesian Shortfin Eel (Anguilla bicolor bicolor McClelland, 1884).

Published in:

Journal of Biological Researches, 2022, v. 28, n. 1, p. 20, doi. 10.23869/bphjbr.28.1.20223

By:

Widiastuti, Nyan Hayu;
Retnoaji, Bambang

Publication type:

Article

EFFECTS OF QUERCETIN ON CYTOKINES AND PULMONARY CAPILLARY CELLS IN PULMONARY ARTERIAL HYPERTENSION RATS.

Published in:

Farmacia, 2021, v. 69, n. 1, p. 155, doi. 10.31925/farmacia.2021.1.21

By:

WEIQUN ZHANG;
YAN LI;
YONG LUO;
DELI YE

Publication type:

Article

Influence of maternal nutrition on placental vascularity and mRNA expression of angiogenic factors (AFs) and their receptors (AFRs) in adolescent sheep.

Published in:

Journal of Animal Science, 2006, v. 84, p. 347

By:

Redmer, D. A.;
Aitken, R. P.;
Milne, J. S.;
Johnson, M. L.;
Rouse, D.;
Borowicz, P. P.;
Borowicz, M.;
Kraft, K. C.;
Reynolds, L. P.;
Luther, J. S.;
Wallace, J. M.

Publication type:

Article

Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia.

Published in:

Free Radical Research, 2012, v. 46, n. 6, p. 705, doi. 10.3109/10715762.2012.669041

By:

Niecknig, Helene;
Tug, Suzan;
Reyes, Buena Delos;
Kirsch, Michael;
Fandrey, Joachim;
Berchner-Pfannschmidt, Utta

Publication type:

Article

High-purity magnesium pin enhances bone consolidation in distraction osteogenesis model through activation of the VHL/HIF-1α/VEGF signaling.

Published in:

Journal of Biomaterials Applications, 2020, v. 35, n. 2, p. 224, doi. 10.1177/0885328220928550

By:

Hamushan, Musha;
Cai, Weijie;
Zhang, Yubo;
Lou, Tengfei;
Zhang, Shaoxiang;
Zhang, Xiaonong;
Cheng, Pengfei;
Zhao, Changli;
Han, Pei

Publication type:

Article

Long-Chain acyl-CoA Synthetase LACS2 Contributes to Submergence Tolerance by Modulating Cuticle Permeability in Arabidopsis.

Published in:

Plants (2223-7747), 2020, v. 9, n. 2, p. 262, doi. 10.3390/plants9020262

By:

Xie, Li-Juan;
Tan, Wei-Juan;
Yang, Yi-Cong;
Tan, Yi-Fang;
Zhou, Ying;
Zhou, De-Mian;
Xiao, Shi;
Chen, Qin-Fang

Publication type:

Article

Neuroprotective effects of quercetin on the cerebellum of zinc oxide nanoparticles (ZnoNps)-exposed rats.

Published in:

Tissue Barriers, 2023, v. 11, n. 3, p. 1, doi. 10.1080/21688370.2022.2115273

By:

Abdelrahman, Shaimaa A.;
El-Shal, Amal S.;
Abdelrahman, Abeer A.;
Saleh, Ebtehal Zaid Hassen;
Mahmoud, Abeer A.

Publication type:

Article

The therapeutic prospect of zinc oxide nanoparticles in experimentally induced diabetic nephropathy.

Published in:

Tissue Barriers, 2023, v. 11, n. 1, p. 1, doi. 10.1080/21688370.2022.2069966

By:

Abd El-Baset, Samia A.;
Mazen, Nehad F.;
Abdul-Maksoud, Rehab S.;
Kattaia, Asmaa A. A.

Publication type:

Article

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.89173

By:

Warnhoff, Kurt;
Bhattacharya, Sushila;
Snoozy, Jennifer;
Breen, Peter C.;
Ruvkun, Gary

Publication type:

Article

Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85597

By:

Ciampa, Erin J.;
Flahardy, Padraich;
Srinivasan, Harini;
Jacobs, Christopher;
Tsai, Linus;
Karumanchi, S. Ananth;
Parikh, Samir M.

Publication type:

Article

Searching for molecular hypoxia sensors among oxygen-dependent enzymes.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87705

By:

Li Li;
Susan Shen;
Bickler, Philip;
Jacobson, Matthew P.;
Wu, Lani F.;
Altschuler, Steven J.

Publication type:

Article

MicroRNA‐186 is associated with hypoxia‐inducible factor‐1α expression in chronic obstructive pulmonary disease.

Published in:

Molecular Genetics & Genomic Medicine, 2019, v. 7, n. 3, p. N.PAG, doi. 10.1002/mgg3.531

By:

Lin, Li;
Sun, Juan;
Wu, Duoyi;
Lin, Daobo;
Sun, Dingwei;
Li, Quanni;
Chen, Jiannan;
Niu, Huan;
He, Ping;
Ding, Yipeng

Publication type:

Article

On the relationship between VDR, RORα and RORγ receptors expression and HIF1‐α levels in human melanomas.

Published in:

Experimental Dermatology, 2019, v. 28, n. 9, p. 1036, doi. 10.1111/exd.14002

By:

Brożyna, Anna A.;
Jóźwicki, Wojciech;
Jetten, Anton M.;
Slominski, Andrzej T.

Publication type:

Article

HIF‐1α‐mediated BMP6 down‐regulation leads to hyperproliferation and abnormal differentiation of keratinocytes in vitro.

Published in:

Experimental Dermatology, 2018, v. 27, n. 11, p. 1287, doi. 10.1111/exd.13785

By:

Kim, Jin Hee;
Bae, Hyun Cheol;
Kim, Jaehyung;
Lee, Hana;
Ryu, Woo‐In;
Jeong, Sang Hoon;
Son, Sang Wook;
Son, Eui Dong;
Lee, Tae Ryong

Publication type:

Article

2 ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1α in vitro.

Published in:

Australasian Journal of Dermatology, 2016, v. 57, n. 2, p. e32, doi. 10.1111/ajd.12340

By:

Long, Fei;
Si, Loubin;
Long, Xiao;
Yang, Bob;
Wang, Xiaojun;
Zhang, Fuquan

Publication type:

Article

Hypoxia suppresses glucose-induced increases in collective cell migration in vascular endothelial cell monolayers.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55706-1

By:

Sone, Kazuki;
Sakamaki, Yuka;
Hirose, Satomi;
Inagaki, Mai;
Tachikawa, Masanori;
Yoshino, Daisuke;
Funamoto, Kenichi

Publication type:

Article

Heatwave resilience of juvenile white sturgeon is associated with epigenetic and transcriptional alterations.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42652-7

By:

Earhart, Madison L.;
Blanchard, Tessa S.;
Strowbridge, Nicholas;
Sheena, Ravinder;
McMaster, Clark;
Staples, Benjamin;
Brauner, Colin J.;
Baker, Daniel W.;
Schulte, Patricia M.

Publication type:

Article

MicroRNA‐22 suppresses NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokine production by targeting the HIF‐1α and NLRP3 in human dental pulp fibroblasts.

Published in:

International Endodontic Journal, 2022, v. 55, n. 11, p. 1225, doi. 10.1111/iej.13814

By:

Jiang, Wenkai;
Sun, Shukai;
Wang, Diya;
Qiu, Jun;
Song, Ya;
Zhang, Qianxia;
He, Wenxi;
Song, Bing;
Zhang, Yaqing;
Wang, Shengchao

Publication type:

Article

Hypoxia‐inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide‐stimulated human dental pulp cells.

Published in:

International Endodontic Journal, 2020, v. 53, n. 5, p. 636, doi. 10.1111/iej.13264

By:

Fujii, M.;
Kawashima, N.;
Tazawa, K.;
Hashimoto, K.;
Nara, K.;
Noda, S.;
Nagai, S.;
Okiji, T.

Publication type:

Article

Sishen Pill and its active phytochemicals in treating inflammatory bowel disease and colon cancer: an overview.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1375585

By:

Boxun Zhang;
Yingying Cheng;
Qin Jian;
Sirui Xiang;
Qi Xu;
Chuchu Wang;
Chuan Yang;
Junzhi Lin;
Chuan Zheng

Publication type:

Article

Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1257450

By:

Lu Zhan;
Fangting Su;
Qiang Li;
Yueqiang Wen;
Feng Wei;
Zhelin He;
Xiaoyan Chen;
Xiang Yin;
Jian Wang;
Yilin Cai;
Yuxia Gong;
Yu Chen;
Xiao Ma;
Jinhao Zeng

Publication type:

Article

Impact of a TAK-1 inhibitor as a single or as an add-on therapy to riociguat on the metabolic reprograming and pulmonary hypertension in the SUGEN5416/hypoxia rat model.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1021535

By:

Morales-Cano, Daniel;
Luis Izquierdo-García, Jose;
Barreira, Bianca;
Esquivel-Ruiz, Sergio;
Callejo, Maria;
Pandolfi, Rachele;
Villa-Valverde, Palmira;
Rodríguez, Ignacio;
Cogolludo, Angel;
Ruiz-Cabello, Jesus;
Perez-Vizcaino, Francisco;
Moreno, Laura

Publication type:

Article

Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1170796

By:

Waldum, Helge

Publication type:

Article

Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1138265

By:

Zhanxue Zhao;
Linxun Liu;
Hekai Chen;
Shuai Li;
Yan Guo;
Xiaofan Hou;
Jinyu Yang

Publication type:

Article

Pathological Features of Enterovirus 71-Associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analysis.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.663019

By:

Jin, Yuefei;
Li, Dong;
Sun, Tiantian;
Du, Yue;
Gao, Yanlei;
Ding, Ronghua;
Ji, Wangquan;
Zhang, Weiguo;
Yang, Haiyan;
Chen, Shuaiyin;
Duan, Guangcai

Publication type:

Article

Intestinal Epithelial Cells-Derived Hypoxia-Inducible Factor-1α Is Essential for the Homeostasis of Intestinal Intraepithelial Lymphocytes.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00806

By:

Sun, Lihua;
Li, Teming;
Tang, Hanlin;
Yu, Kun;
Ma, Yuanhang;
Yu, Min;
Qiu, Yuan;
Xu, Pengyuan;
Xiao, Weidong;
Yang, Hua

Publication type:

Article

The Activin Receptor, Activin-Like Kinase 4, Mediates Toxoplasma Gondii Activation of Hypoxia Inducible Factor-1.

Published in:

Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. N.PAG, doi. 10.3389/fcimb.2019.00036

By:

Lis, Agnieszka;
Wiley, Mandi;
Vaughan, Joan;
Gray, Peter C.;
Blader, Ira J.

Publication type:

Article

Ifu5, a WW domain‐containing protein interacts with Efg1 to achieve coordination of normoxic and hypoxic functions to influence pathogenicity traits in Candida albicans.

Published in:

Cellular Microbiology, 2020, v. 22, n. 2, p. N.PAG, doi. 10.1111/cmi.13140

By:

Rastogi, Sumit K.;
Wijlick, Lasse;
Ror, Shivani;
Lee, Keunsook K.;
Román, Elvira;
Agarwal, Pranjali;
Manzoor, Nikhat;
Gow, Neil A.R.;
Pla, Jesús;
Ernst, Joachim F.;
Panwar, Sneh L.

Publication type:

Article

Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis.

Published in:

Oncogene, 2015, v. 34, n. 36, p. 4758, doi. 10.1038/onc.2014.411

By:

Zeng, L;
Morinibu, A;
Kobayashi, M;
Zhu, Y;
Wang, X;
Goto, Y;
Yeom, C J;
Zhao, T;
Hirota, K;
Shinomiya, K;
Itasaka, S;
Yoshimura, M;
Guo, G;
Hammond, E M;
Hiraoka, M;
Harada, H

Publication type:

Article

Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis.

Published in:

Oncogene, 2015, v. 34, n. 36, p. 4713, doi. 10.1038/onc.2014.396

By:

Singleton, D C;
Rouhi, P;
Zois, C E;
Haider, S;
Li, J-L;
Kessler, B M;
Cao, Y;
Harris, A L

Publication type:

Article