Works matching DE "POLY(ADP-ribose) polymerase"
Results: 1083
Current Advances in PARP1‐Targeted Theranostics.
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- Journal of Labelled Compounds & Radiopharmaceuticals, 2025, v. 68, n. 1/2, p. 1, doi. 10.1002/jlcr.4135
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- Publication type:
- Article
Incidence, characteristics and outcome of therapy‐related myeloid neoplasms in women with epithelial ovarian cancer after exposure to poly‐ADPribose polymerase inhibitors: A cancer center experience.
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- International Journal of Cancer, 2025, v. 156, n. 9, p. 1686, doi. 10.1002/ijc.35299
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- Article
Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia.
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- Immunity, Inflammation & Disease, 2025, v. 13, n. 1, p. 1, doi. 10.1002/iid3.70106
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- Article
Optimal use, combinations, and sequencing of therapies in advanced prostate cancer.
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- Expert Review of Clinical Pharmacology, 2025, v. 18, n. 1/2, p. 13, doi. 10.1080/17512433.2025.2451643
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- Publication type:
- Article
The efficacy of Veliparib in combination with chemotherapy in the treatment of lung cancer: systematic review and meta-analysis.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 12, p. 1237, doi. 10.1080/14737140.2024.2417770
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- Article
Current uses and resistance mechanisms of enzalutamide in prostate cancer treatment.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 11, p. 1085, doi. 10.1080/14737140.2024.2405103
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- Publication type:
- Article
PARP inhibitor resistance mechanisms and PARP inhibitor derived imaging probes.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 10, p. 989, doi. 10.1080/14737140.2024.2398494
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- Article
Strategies for the prevention or reversal of PARP inhibitor resistance.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 10, p. 959, doi. 10.1080/14737140.2024.2393251
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- Publication type:
- Article
Safety and hematological toxicities of PARP inhibitors in patients with cancer: a systematic review of randomized controlled trials and a pharmacovigilance analysis.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 7, p. 613, doi. 10.1080/14737140.2024.2357822
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- Publication type:
- Article
Efficacy and safety of neoadjuvant therapy for HR-positive/HER2-negative early breast cancer: a Bayesian network meta-analysis.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 7, p. 599, doi. 10.1080/14737140.2024.2350105
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- Publication type:
- Article
Efficacy and Safety of Combination Therapy with PARP Inhibitors and Anti-Angiogenic Agents in Ovarian Cancer: A Systematic Review and Meta-Analysis.
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- Journal of Clinical Medicine, 2025, v. 14, n. 5, p. 1776, doi. 10.3390/jcm14051776
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- Publication type:
- Article
Olaparib increases chemosensitivity by upregulating miR-125a-3p in ovarian cancer cells.
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- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02048-7
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- Publication type:
- Article
Comprehensive dataset of interactors for the entire PARP family using TurboID proximity labeling.
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- Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-04722-5
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- Publication type:
- Article
Stem Cell Transplantation for Ovarian Cancer Patient with Associated Myelodysplasia After Maintenance Therapy with Olaparib: A Case Report.
- Published in:
- 2025
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- Publication type:
- Case Study
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1519066
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- Publication type:
- Article
Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue.
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- Regulatory Mechanisms in Biosystems, 2019, v. 10, n. 1, p. 103, doi. 10.15421/021916
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- Publication type:
- Article
Efficacy comparison of PD-1/PD-L1 inhibitor monotherapy and combination with PARPis or antiangiogenic agents in advanced or recurrent endometrial cancer: a systematic review and network meta-analysis.
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- BMC Women's Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12905-025-03612-7
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- Publication type:
- Article
Capturing a Pentacyclic Fragment‐Based Library Derived from Perophoramidine: Their Design, Synthesis and Evaluation as Anticancer Compounds by DNA Double‐Strand Breaks (DSB) and PARP‐1 Inhibition.
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- Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202202405
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- Publication type:
- Article
Effects of small nucleolar RNA SNORD44 on the proliferation, apoptosis and invasion of glioma cells.
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- Histochemistry & Cell Biology, 2020, v. 153, n. 4, p. 257, doi. 10.1007/s00418-020-01848-y
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- Publication type:
- Article
Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells.
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- Pharmaceutical Chemistry Journal, 2020, v. 53, n. 11, p. 1036, doi. 10.1007/s11094-020-02119-9
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- Publication type:
- Article
Nanoparticles-SIRT1 Prevents Endothelial Progenitor Cells Senescence by Modulating Nitric Oxide Expression and Reducing Poly ADP-ribose Polymerase: In vitro Study.
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- Trends in Sciences, 2024, v. 21, n. 6, p. 1, doi. 10.48048/tis.2024.7519
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- Publication type:
- Article
Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme.
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- Turkish Journal of Chemistry, 2019, v. 43, n. 5, p. 1290, doi. 10.3906/kim-1905-15
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- Publication type:
- Article
Revealing the selective mechanisms of inhibitors to PARP-1 and PARP-2 via multiple computational methods.
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- PeerJ, 2020, p. 1, doi. 10.7717/peerj.9241
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- Publication type:
- Article
Downfall of Iniparib: A PARP Inhibitor That Doesn't Inhibit PARP After All.
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- JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 1, p. 1, doi. 10.1093/jnci/djt447
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- Publication type:
- Article
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2276665
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- Publication type:
- Article
Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 952, doi. 10.1080/14756366.2022.2053524
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- Publication type:
- Article
1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1968, doi. 10.1080/14756366.2021.1972993
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- Publication type:
- Article
Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP).
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1916, doi. 10.1080/14756366.2021.1969386
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- Publication type:
- Article
Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1).
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1606, doi. 10.1080/14756366.2020.1804382
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- Publication type:
- Article
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 880, doi. 10.1080/14756366.2020.1740692
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- Publication type:
- Article
Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-κB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats.
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- Neurological Sciences, 2013, v. 34, n. 12, p. 2101, doi. 10.1007/s10072-013-1344-6
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- Article
Association of poly(ADP-ribose) polymerase-1 polymorphism with Tourette syndrome.
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- Neurological Sciences, 2013, v. 34, n. 11, p. 1911, doi. 10.1007/s10072-013-1405-x
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- Publication type:
- Article
BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia.
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- 2022
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- Publication type:
- journal article
Cases of consecutive ductal adenocarcinoma of the prostate carrying HRR mutation: case series and literature review.
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- Oxford Medical Case Reports, 2024, v. 2024, n. 10, p. 1, doi. 10.1093/omcr/omae124
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- Publication type:
- Article
Nicotinamide riboside supplementation does not alter whole‐body or skeletal muscle metabolic responses to a single bout of endurance exercise.
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- Journal of Physiology, 2021, v. 599, n. 5, p. 1513, doi. 10.1113/JP280825
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- Publication type:
- Article
A Novel Combination of Ruthenium Polypyridyl Complex, [Ru(dppz)2PiP]<sup>2+</sup> and PARP Inhibitor, NU1025 for Cancer Treatment.
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- Malaysian Journal of Medicine & Health Sciences, 2019, v. 15, p. 26
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- Publication type:
- Article
Myeloid malignancies in cancer patients treated with poly(ADP-ribose) polymerase (PARP) inhibitors: a case series.
- Published in:
- 2022
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- Publication type:
- Letter
PLK1 overexpression suppresses homologous recombination and confers cellular sensitivity to PARP inhibition.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-82724-w
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- Publication type:
- Article
PARP inhibition radiosensitizes BRCA1 wildtype and mutated breast cancer to proton therapy.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-81914-w
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- Publication type:
- Article
Cooperative dynamics of PARP-1 zinc-finger domains in the detection of DNA single-strand breaks.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-73707-y
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- Publication type:
- Article
Safety assessments and clinical features of PARP inhibitors from real-world data of Japanese patients with ovarian cancer.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-63600-z
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- Publication type:
- Article
5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 2, p. 249, doi. 10.3390/brainsci11020249
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- Publication type:
- Article
Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells.
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- Brain Sciences (2076-3425), 2020, v. 10, n. 12, p. 959, doi. 10.3390/brainsci10120959
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- Publication type:
- Article
iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer.
- Published in:
- Biomolecules (2218-273X), 2025, v. 15, n. 1, p. 125, doi. 10.3390/biom15010125
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- Publication type:
- Article
Poly(ADP-Ribose) Polymerase (PARP) Inhibitors for Cancer Therapy: Advances, Challenges, and Future Directions.
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- Biomolecules (2218-273X), 2024, v. 14, n. 10, p. 1269, doi. 10.3390/biom14101269
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- Publication type:
- Article
Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET.
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- Biomolecules (2218-273X), 2024, v. 14, n. 9, p. 1071, doi. 10.3390/biom14091071
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- Publication type:
- Article
Combination Treatment Strategies to Overcome PARP Inhibitor Resistance.
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- Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1480, doi. 10.3390/biom13101480
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- Publication type:
- Article
The Role of Poly(ADP-ribose) Polymerase 1 in Nuclear and Mitochondrial Base Excision Repair.
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- Biomolecules (2218-273X), 2023, v. 13, n. 8, p. 1195, doi. 10.3390/biom13081195
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- Publication type:
- Article
Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and Calpain.
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- Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 581, doi. 10.3390/biom13040581
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- Publication type:
- Article
Metabolic Activation of PARP as a SARS-CoV-2 Therapeutic Target—Is It a Bait for the Virus or the Best Deal We Could Ever Make with the Virus? Is AMBICA the Potential Cure?
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 374, doi. 10.3390/biom13020374
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- Publication type:
- Article