Works matching DE "T-cell exhaustion"

Results: 806

Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04410-6

By:

Fan, Ruirui;
Gao, Jie;
Chen, Jin

Publication type:

Article

Targeting CD39 boosts PD-1 blockade antitumor therapeutic efficacy via strengthening CD8 + TILs function and recruiting B cells in cervical cancer.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03500-0

By:

Jiang, Lili;
Wu, Tong;
Qu, Xinyu;
Li, Shuqi;
Jiang, Qi'an;
Ren, Tingting;
Liang, Jiali;
Ding, Yan;
Hua, Keqin;
Tang, Zhongmin;
Qiu, Junjun

Publication type:

Article

The mechanism of EZH2/H3K27me3 downregulating CXCL10 to affect CD8+ T cell exhaustion to participate in the transformation from myelodysplastic syndrome to acute myeloid leukaemia.

Published in:

British Journal of Haematology, 2025, v. 206, n. 5, p. 1335, doi. 10.1111/bjh.20066

By:

Zheng, Zhuanzhen;
Wang, Wenjing;
Feng, Mengjing;
Chen, Xiuhua;
Ren, Fanggang;
Hou, Yanfei

Publication type:

Article

B and T lymphocyte attenuator (BTLA) and PD-1 pathway dual blockade promotes antitumor immune responses by reversing CD8+ T-cell exhaustion in non-small cell lung cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1553042

By:

Zhang, Yang;
Yang, Yang;
Zeng, Yuanyuan;
Qu, Qiuxia;
Shen, Dan;
Mu, Chuanyong;
Lei, Wei;
Su, Meiqin;
Mao, Jingyu;
Gao, Lirong;
Liu, Zeyi;
Chen, Cheng;
Huang, Jian-an

Publication type:

Article

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60463-4

By:

Zhang, Xuhao;
Gao, Yu;
Liao, Huiping;
Wang, Wenyan;
Yang, Zaili;
Cao, Weian;
Li, Ge;
Wen, Jing;
Han, Gencheng;
Fu, Yang-Xin

Publication type:

Article

Editorial: Harnessing single-cell insights: pioneering predictive markers for immunotherapy efficacy in solid tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1625920

By:

Zhou, Zhongbao

Publication type:

Article

Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01110-1

By:

Heming, Michael;
Haessner, Svea;
Wolbert, Jolien;
Lu, I-Na;
Li, Xiaolin;
Brokinkel, Benjamin;
Müther, Michael;
Holling, Markus;
Stummer, Walter;
Thomas, Christian;
Schulte-Mecklenbeck, Andreas;
de Faria, Flavia;
Stoeckius, Marlon;
Hailfinger, Stephan;
Lenz, Georg;
Kerl, Kornelius;
Wiendl, Heinz;
Meyer zu Hörste, Gerd;
Grauer, Oliver M.

Publication type:

Article

Low‐Level Viremia Reduces Immune Checkpoint Inhibitor Efficacy in Unresectable HCC: Key Considerations.

Published in:

Liver International, 2025, v. 45, n. 6, p. 1, doi. 10.1111/liv.70122

By:

Xie, Yihang

Publication type:

Article

Desmocollin-3 and Bladder Cancer.

Published in:

Diseases, 2025, v. 13, n. 5, p. 131, doi. 10.3390/diseases13050131

By:

Shukla, Chandreshwar P.;
Jain, Nayan K.;
O'Donnell, Michael A.;
Vachhani, Kapil V.;
Patel, Rashmi;
Patel, Janki;
Modi, Rajiv;
Dheeraj, Arpit;
Lee, Jee Min;
Rolig, Annah;
Malhotra, Sanjay V.;
Khamar, Bakulesh

Publication type:

Article

Bioinformatics prediction of function of T-cell exhaustion related genes in ischemic stroke.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03724-y

By:

Gao, Yajun;
Bai, Ruyu;
Gao, Bo;
Li, Ma

Publication type:

Article

Reply to Al-Ward et al. : HIV, Sepsis, and Postdischarge Mortality in Sub-Saharan Africa.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 6, p. 1105, doi. 10.1164/rccm.202412-2489LE

By:

Cummings, Matthew J.;
Bakamutumaho, Barnabas;
O'Donnell, Max R.

Publication type:

Article

HIV, Sepsis, and Postdischarge Mortality in Sub-Saharan Africa.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 6, p. 1103, doi. 10.1164/rccm.202411-2237LE

By:

Al-Ward, Hisham;
Alnadhary, Alaa;
Chen, Wei;
Sun, Yi Eve

Publication type:

Article

Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451676

By:

Mondal, Antara;
Jamal, Faisal;
Das, Arpita;
Sahoo, Arnab Kumar;
Chaudhary, Khushboo;
Chowdhury, Sarmili;
Jha, Aakriti;
Singha, Santiswarup

Publication type:

Article

Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60457-2

By:

Lehrich, Brandon M.;
Delgado, Evan R.;
Yasaka, Tyler M.;
Liu, Silvia;
Cao, Catherine;
Liu, Yuqing;
Taheri, Mohammad N.;
Guan, Xiangnan;
Koeppen, Hartmut;
Singh, Sucha;
Meadows, Vik;
Liu, Jia-Jun;
Singh-Varma, Anya;
Krutsenko, Yekaterina;
Poddar, Minakshi;
Hitchens, T. Kevin;
Foley, Lesley M.;
Liang, Binyong;
Rialdi, Alex;
Rai, Ravi P.

Publication type:

Article

Tumor-specific CXCR6 positive precursor CD8+ T cells mediate tumor control in metastatic melanoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 693, doi. 10.1007/s13402-025-01040-1

By:

Song, Yang;
Chen, Ji;
Zhang, Yaqin;
Wu, Ning;
Zhu, Yongjun;
Chen, Gang;
Miao, Feng;
Chen, Zhiming;
Wang, Yiqing

Publication type:

Article

Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1534768

By:

Huang, Hua;
Ma, Jiaze;
Kang, An;
Guo, Tianwei;
Sun, Wei;
Xu, Yan;
Ji, Lijiang

Publication type:

Article

The Spatial Proximity of CD8 + FoxP3 + PD-1 + Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 262, doi. 10.3390/curroncol32050262

By:

Hu, Zijuan;
Hu, Zhihuang;
Chen, Keji;
Huang, Huixia;
Zhong, Xinyang;
Wang, Yaxian;
Chen, Jiayu;
He, Xuefeng;
Shi, Di;
Zeng, Yupeng;
Li, Jiwei;
Zhou, Xiaoyan;
Wei, Ping

Publication type:

Article

Overexpression of mRNA Leukocyte‐Associated Immunoglobulin‐Like Receptor 2 (LAIR‐2) Levels Correlates With Immune Cell Subtype Infiltration, T Cell Exhaustion, and Its Prognostic Potential in Hepatocellular Carcinoma.

Published in:

Journal of Medical Virology, 2025, v. 97, n. 5, p. 1, doi. 10.1002/jmv.70417

By:

Ibrahim, Aya Mohamed Ahmed;
Abd El‐Fattah, Abeer I.;
Shaker, Olfat Gamil;
Youssef, Ahmed A.

Publication type:

Article

Single‐Cell Atlas of the Peripheral Immune Response in Patients With Chronic Hepatitis B.

Published in:

Journal of Medical Virology, 2025, v. 97, n. 5, p. 1, doi. 10.1002/jmv.70360

By:

Huang, Li;
Ye, Bo;
Cao, Feinan;
Ruan, Bing;
Li, Xuefen

Publication type:

Article

Targeting BATF2-RGS2 axis reduces T-cell exhaustion and restores anti-tumor immunity.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02351-5

By:

Gu, Xuyu;
Gao, Chanchan;
Su, Xiangyu;
Zhu, Yaoyao;
Fang, Qiyu;
Yu, Jia;
Wang, Ziming;
Zhao, Deping;
Zhang, Wentian

Publication type:

Article

Effects of sex and obesity on immune checkpoint inhibition-related cardiac systolic dysfunction in aged mice.

Published in:

Basic Research in Cardiology, 2025, v. 120, n. 1, p. 207, doi. 10.1007/s00395-024-01088-4

By:

Sayour, Nabil V.;
Kucsera, Dániel;
Alhaddad, Ayham R.;
Tóth, Viktória É.;
Gergely, Tamás G.;
Kovács, Tamás;
Hegedűs, Zsombor I.;
Jakab, Márk E.;
Ferdinandy, Péter;
Varga, Zoltán V.

Publication type:

Article

ANCA-associated vasculitis and lung cancer: an immunological perspective.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01475-0

By:

Li, Longzhao;
Teng, Jun;
Kou, Na;
Yue, Yuan;
Wang, HongWu

Publication type:

Article

A 3D Ex Vivo Tumor‐Immune Coculture System Mimicking In Vivo Tumor Environmental Stress on CD8+ T Cells Exhaustion (Adv. Biology 7/2023).

Published in:

Advanced Biology, 2023, v. 7, n. 7, p. 1, doi. 10.1002/adbi.202370071

By:

Meng, Zhouwenli;
Niu, Xiaomin;
Xia, Liliang;
Chen, Yingying;
Wang, Zhen;
Wang, Hui;
Ji, Ping;
Cui, Wenguo;
Wang, Ying;
Lu, Shun

Publication type:

Article

A 3D Ex Vivo Tumor‐Immune Coculture System Mimicking In Vivo Tumor Environmental Stress on CD8+ T Cells Exhaustion.

Published in:

Advanced Biology, 2023, v. 7, n. 7, p. 1, doi. 10.1002/adbi.202200264

By:

Meng, Zhouwenli;
Niu, Xiaomin;
Xia, Liliang;
Chen, Yingying;
Wang, Zhen;
Wang, Hui;
Ji, Ping;
Cui, Wenguo;
Wang, Ying;
Lu, Shun

Publication type:

Article

Indole-3-carbinol prevented tumor progression and potentiated PD1ab therapy by upregulating PTEN in colorectal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01887-8

By:

Chen, Hao;
Gao, Baojuan;
Li, Jiezhuang;
Liu, Liehui;
Zhang, Yufang;
Shuai, Mengting;
Ji, Yuran

Publication type:

Article

Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and bulk RNA-seq.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01812-z

By:

Shi, Yulin;
Yu, Yang;
Zhao, Jiahan;
Huang, Linan;
Wang, Qingyang;
Sun, Qi;
Liu, Lijuan;
Sun, Changgang

Publication type:

Article

T cell exhaustion methylation signature drives differential immune responses in glioblastoma.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01412-3

By:

Chen, Feng;
Qian, Wen-Bo;
Chen, Zhen-Hua;
Qian, Jun;
Luo, Chun

Publication type:

Article

Pan-cancer analysis for the prognostic and immunological role of CD47: interact with TNFRSF9 inducing CD8 + T cell exhaustion.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00951-z

By:

Liang, Hongxin;
Zheng, Yong;
Huang, Zekai;
Dai, Jinchi;
Yao, Lintong;
Xie, Daipeng;
Chen, Duo;
Qiu, Hongrui;
Wang, Huili;
Li, Hao;
Leng, Jinhang;
Tang, Ziming;
Zhang, Dongkun;
Zhou, Haiyu

Publication type:

Article

Effect of Annexin A2 on prognosis and sensitivity to immune checkpoint plus tyrosine kinase inhibition in metastatic renal cell carcinoma.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00934-0

By:

Wang, Jiajun;
Lin, Jinglai;
Wang, Jiahao;
Wang, Ying;
Zhu, Yanjun;
Xu, Xianglai;
Guo, Jianming

Publication type:

Article

Interferon signaling and ferroptosis in tumor immunology and therapy.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00668-w

By:

Hu, Wei;
Zhao, Ziqian;
Du, Jianxin;
Jiang, Jie;
Yang, Minghao;
Tian, Maojin;
Zhao, Peiqing

Publication type:

Article

Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer census.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00660-4

By:

Wei, Chen;
Ma, Yijie;
Wang, Mengyu;
Wang, Siyi;
Yu, Wenyue;
Dong, Shuailei;
Deng, Wenying;
Bie, Liangyu;
Zhang, Chi;
Shen, Wei;
Xia, Qingxin;
Luo, Suxia;
Li, Ning

Publication type:

Article

Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer census.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00660-4

By:

Wei, Chen;
Ma, Yijie;
Wang, Mengyu;
Wang, Siyi;
Yu, Wenyue;
Dong, Shuailei;
Deng, Wenying;
Bie, Liangyu;
Zhang, Chi;
Shen, Wei;
Xia, Qingxin;
Luo, Suxia;
Li, Ning

Publication type:

Article

Multi-omics analysis unveils immunosuppressive microenvironment in the occurrence and development of multiple pulmonary lung cancers.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00651-5

By:

Zhang, Jiatao;
Zhou, Wenhao;
Li, Na;
Li, Huaming;
Luo, Haitao;
Jiang, Benyuan

Publication type:

Article

A breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00482-w

By:

Hu, Haihong;
Zou, Mingxiang;
Hu, Hongjuan;
Hu, Zecheng;
Jiang, Lingxiang;
Escobar, David;
Zhu, Hongxia;
Zhan, Wendi;
Yan, Ting;
Zhang, Taolan

Publication type:

Article

Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00403-x

By:

Barrera, Cristian;
Corredor, Germán;
Viswanathan, Vidya Sankar;
Ding, Ruiwen;
Toro, Paula;
Fu, Pingfu;
Buzzy, Christina;
Lu, Cheng;
Velu, Priya;
Zens, Philipp;
Berezowska, Sabina;
Belete, Merzu;
Balli, David;
Chang, Han;
Baxi, Vipul;
Syrigos, Konstantinos;
Rimm, David L.;
Velcheti, Vamsidhar;
Schalper, Kurt;
Romero, Eduardo

Publication type:

Article

Longitudinal analysis of peripheral immune cells in patients with multiple sclerosis treated with anti‐CD20 therapy.

Published in:

Annals of Clinical & Translational Neurology, 2024, v. 11, n. 10, p. 2657, doi. 10.1002/acn3.52182

By:

Waede, Mie;
Voss, Lasse F.;
Kingo, Christina;
Moeller, Jesper B.;
Elkjaer, Maria L.;
Illes, Zsolt

Publication type:

Article

Effective γδ T‐cell clinical therapies: current limitations and future perspectives for cancer immunotherapy.

Published in:

Clinical & Translational Immunology, 2024, v. 13, n. 2, p. 1, doi. 10.1002/cti2.1492

By:

Revesz, Isabella A;
Joyce, Paul;
Ebert, Lisa M;
Prestidge, Clive A

Publication type:

Article

CD39 expression defines exhausted CD4+ T cells associated with poor survival and immune evasion in human gastric cancer.

Published in:

Clinical & Translational Immunology, 2024, v. 13, n. 3, p. 1, doi. 10.1002/cti2.1499

By:

Duan, Zhen‐quan;
Li, Yu‐xian;
Qiu, Yuan;
Shen, Yang;
Wang, Ying;
Zhang, Yuan‐yuan;
Zhu, Bao‐hang;
Yu, Xiao‐hong;
Tan, Xue‐ling;
Chen, Weisan;
Zhuang, Yuan;
Cheng, Ping;
Zhang, Wei‐jun;
Zou, Quan‐ming;
Ma, Dai‐yuan;
Peng, Liu‐sheng

Publication type:

Article

Integrative analysis of bulk and single-cell sequencing reveals TNFSF9 as a potential regulator in microsatellite instability stomach adenocarcinoma.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02471-0

By:

Zhou, Jianlong;
Zhang, Yucheng;
Liu, Yongfeng;
Li, Jiehui;
Zhang, Wenxing;
Wang, Junjiang;
Yao, Xueqing;
Feng, Huolun;
Zheng, Jiabin;
Li, Yong

Publication type:

Article

Mitochondrial function changes in T cell subsets during radiotherapy for patients with nasopharyngeal carcinoma.

Published in:

Oncology Letters, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/ol.2025.15019

By:

Wang, Quan;
Yin, Xiangzhi;
Liu, Hongbo;
Wang, Qing;
Zhang, Lu;
Wang, Yifan;
Lu, Haijun

Publication type:

Article

Synergistic upregulation of PD‑L1 in tumor cells and CD39 in tumor‑infiltrating CD8+ T cells leads to poor prognosis in patients with hepatocellular carcinoma.

Published in:

Oncology Letters, 2024, v. 28, n. 2, p. N.PAG, doi. 10.3892/ol.2024.14501

By:

Kang, Xi;
Zhao, Sinan;
Lin, Shan;
Li, Jing;
Wang, Shunxiang

Publication type:

Article

Investigating chimeric antigen receptor T cell therapy and the potential for cancer immunotherapy (Review).

Published in:

Molecular & Clinical Oncology, 2023, v. 19, n. 6, p. N.PAG, doi. 10.3892/mco.2023.2691

By:

Poojary, Rayansh;
Song, Andy Fang;
Song, Benny Shone;
Song, Carly Shaw;
Wang, Liqing;
Song, Jianxun

Publication type:

Article

SPECIFIC: A systematic framework for engineering cell state‐responsive synthetic promoters reveals key regulators of T cell exhaustion.

Published in:

Quantitative Biology, 2025, v. 13, n. 2, p. 1, doi. 10.1002/qub2.97

By:

Zhang, Zhaoyu;
Qiu, Xiaoyu;
Ning, Hui;
Huang, Zihua;
Tao, Minzhen;
Liang, Min;
Xie, Zhen

Publication type:

Article

A Comprehensive Comparison between Primary Liver Cancer and Liver Metastases through scRNA-Seq Data Analysis.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 2, p. 90, doi. 10.3390/metabo14020090

By:

Hao, Shuang;
Chen, Liqun;
Du, Wenhui;
Sun, Huiyan

Publication type:

Article

Helicobacter pylori Eradication Is Associated With a Reduced Risk of Metachronous Gastric Neoplasia by Restoring Immune Function in the Gastric Mucosa.

Published in:

Helicobacter, 2025, v. 30, n. 2, p. 1, doi. 10.1111/hel.70030

By:

Kim, Min‐Jae;
Je, Yeonjin;
Chun, Jaeyoung;
Youn, Young Hoon;
Park, Hyojin;
Nahm, Ji Hae;
Kim, Jie‐Hyun

Publication type:

Article

Cochlear inflammaging: cellular and molecular players of the innate and adaptive immune system in age-related hearing loss.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1308823

By:

Parekh, Shailee;
Kaur, Tejbeer

Publication type:

Article

Sustained improvement in IPEX-like syndrome course following failed umbilical cord blood transplantation.

Published in:

Pediatric Hematology & Oncology, 2024, v. 41, n. 3, p. 246, doi. 10.1080/08880018.2023.2273876

By:

Alkooheji, Ishaq;
Secord, Elizabeth;
Buggs-Saxton, Colleen;
Lulgjuraj, Tony;
Savaşan, Süreyya

Publication type:

Article

Exploring the Regulation and Function of Rpl3l in the Development of Early-Onset Dilated Cardiomyopathy and Congestive Heart Failure Using Systems Genetics Approach.

Published in:

Genes, 2024, v. 15, n. 1, p. 53, doi. 10.3390/genes15010053

By:

Bajpai, Akhilesh K.;
Gu, Qingqing;
Orgil, Buyan-Ochir;
Alberson, Neely R.;
Towbin, Jeffrey A.;
Martinez, Hugo R.;
Lu, Lu;
Purevjav, Enkhsaikhan

Publication type:

Article

The Interplay between T Cells and Cancer: The Basis of Immunotherapy.

Published in:

Genes, 2023, v. 14, n. 5, p. 1008, doi. 10.3390/genes14051008

By:

Chen, Christina;
Liu, Xin;
Chang, Che-Yu;
Wang, Helen Y.;
Wang, Rong-Fu

Publication type:

Article

Exogenous Nucleotides Mitigate Cardiac Aging in SAMP8 Mice by Modulating Energy Metabolism Through AMPK Pathway.

Published in:

Nutrients, 2024, v. 16, n. 22, p. 3851, doi. 10.3390/nu16223851

By:

Wu, Yuxiao;
Liu, Rui;
Wei, Chan;
Wang, Xiujuan;
Wu, Xin;
Li, Yong;
Xu, Meihong

Publication type:

Article