Works matching DE "NUCLEAR receptors (Biochemistry)"

Results: 3061

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 9, p. 760, doi. 10.1038/nsmb.2877

By:

Conomos, Dimitri;
Reddel, Roger R;
Pickett, Hilda A

Publication type:

Article

Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 277, doi. 10.1038/nsmb.2778

By:

Lou, Xiaohua;
Toresson, Gudrun;
Benod, Cindy;
Suh, Ji Ho;
Philips, Kevin J;
Webb, Paul;
Gustafsson, Jan-Ake

Publication type:

Article

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 2, p. 182, doi. 10.1038/nsmb.2476

By:

You, Seo-Hee;
Lim, Hee-Woong;
Sun, Zheng;
Broache, Molly;
Won, Kyoung-Jae;
Lazar, Mitchell A

Publication type:

Article

DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1168, doi. 10.1038/nsmb.2400

By:

Hu, QiDong;
Tanasa, Bogdan;
Trabucchi, Michele;
Li, Wenbo;
Zhang, Jie;
Ohgi, Kenneth A;
Rose, David W;
Glass, Christopher K;
Rosenfeld, Michael G

Publication type:

Article

Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 5, p. 532, doi. 10.1038/nsmb.2279

By:

Musille, Paul M;
Pathak, Manish C;
Lauer, Janelle L;
Hudson, William H;
Griffin, Patrick R;
Ortlund, Eric A

Publication type:

Article

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 564, doi. 10.1038/nsmb.2054

By:

Rochel, Natacha;
Ciesielski, Fabrice;
Godet, Julien;
Moman, Edelmiro;
Roessle, Manfred;
Peluso-Iltis, Carole;
Moulin, Martine;
Haertlein, Michael;
Callow, Phil;
Mély, Yves;
Svergun, Dmitri I.;
Moras, Dino

Publication type:

Article

DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 556, doi. 10.1038/nsmb.2046

By:

Jun Zhang;
Chalmers, Michael J.;
Stayrook, Keith R.;
Burris, Lorri L.;
Yongjun Wang;
Busby, Scott A.;
Pascal, Bruce D.;
Garcia-Ordonez, Ruben D.;
Bruning, John B.;
Istrate, Monica A.;
Kojetin, Douglas J.;
Dodge, Jeffrey A.;
Burris, Thomas P.;
Griffin, Patrick R.

Publication type:

Article

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction.

Published in:

2010

By:

Phelan, Caroline A.;
Gampe, Robert T.;
Lambert, Millard H.;
Parks, Derek J.;
Montana, Valerie;
Bynum, Jane;
Broderick, Timothy M.;
Xiao Hu;
Williams, Shawn P.;
Nolte, Robert T.;
Lazar, Mitchell A.

Publication type:

Bibliography

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 4, p. 365, doi. 10.1038/nsmb.1576

By:

Zhao, Chunnian;
Sun, GuoQiang;
Li, Shengxiu;
Shi, Yanhong

Publication type:

Article

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1207, doi. 10.1038/nsmb1344

By:

Raghuram, Srilatha;
Stayrook, Keith R.;
Huang, Pengxiang;
Rogers, Pamela M.;
Nosie, Amanda K.;
McClure, Don B.;
Burris, Lorri L.;
Khorasanizadeh, Sepideh;
Burris, Thomas P.;
Rastinejad, Fraydoon

Publication type:

Article

Nuclear Receptor Expression Defines a Set of Prognostic Biomarkers for Lung Cancer.

Published in:

PLoS Medicine, 2010, v. 7, n. 12, p. 1, doi. 10.1371/journal.pmed.1000378

By:

Yangsik Jeong;
Yang Xie;
Guanghua Xiao;
Behrens, Carmen;
Girard, Luc;
Wistuba, Ignacio I.;
Minna, John D.;
Mangelsdorf, David J.

Publication type:

Article

Two-hybrid yeast test system for assessment of estrogenic activity of chemical compounds.

Published in:

Doklady Biochemistry & Biophysics, 2005, v. 401, n. 1-6, p. 111, doi. 10.1007/s10628-005-0046-2

By:

Kozhemyako, V. B.;
Koval'chuk, S. N.;
Rasskazov, V. A.;
Aminin, D. L.

Publication type:

Article

A Natural-Product Switch for a Dynamic Protein Interface.

Published in:

Angewandte Chemie, 2014, v. 126, n. 25, p. 6561, doi. 10.1002/ange.201403773

By:

Scheepstra, Marcel;
Nieto, Lidia;
Hirsch, Anna K. H.;
Fuchs, Sascha;
Leysen, Seppe;
Lam, Chan Vinh;
in het Panhuis, Leslie;
van Boeckel, Constant A. A.;
Wienk, Hans;
Boelens, Rolf;
Ottmann, Christian;
Milroy, Lech-Gustav;
Brunsveld, Luc

Publication type:

Article

A Photocleavable Masked Nuclear‐Receptor Ligand Enables Temporal Control of C. elegans Development.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2142, doi. 10.1002/ange.201307465

By:

Judkins, Joshua C.;
Mahanti, Parag;
Hoffman, Jacob B.;
Yim, Isaiah;
Antebi, Adam;
Schroeder, Frank C.

Publication type:

Article

A Photocleavable Masked Nuclear-Receptor Ligand Enables Temporal Control of C. elegans Development.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2142, doi. 10.1002/ange.201307465

By:

Judkins, Joshua C.;
Mahanti, Parag;
Hoffman, Jacob B.;
Yim, Isaiah;
Antebi, Adam;
Schroeder, Frank C.

Publication type:

Article

Nuclear localization signal region in nuclear receptor PXR governs the receptor association with mitotic chromatin.

Published in:

Chromosome Research, 2018, v. 26, n. 4, p. 255, doi. 10.1007/s10577-018-9583-2

By:

Rana, Manjul;
Dash, Amit K.;
Ponnusamy, Kalaiarasan;
Tyagi, Rakesh K.

Publication type:

Article

Bilirubin as a signaling molecule.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 4, p. 1335, doi. 10.1002/med.21660

By:

Vítek, Libor

Publication type:

Article

A review of the molecular design and biological activities of RXR agonists.

Published in:

Medicinal Research Reviews, 2019, v. 39, n. 4, p. 1372, doi. 10.1002/med.21578

By:

Almeida, Nathalia Rodrigues;
Conda‐Sheridan, Martin

Publication type:

Article

Identification of NR1I2 genetic variation using resequencing.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 6, p. 547, doi. 10.1007/s00228-007-0295-3

By:

King, Cristi R.;
Ming Xiao;
Jinsheng Yu;
Minton, Matthew R.;
Addleman, Nicholas J.;
Van Booven, Derek J.;
Pui-Yan Kwok;
McLeod, Howard L.;
Marsh, Sharon

Publication type:

Article

Functions of pregnane X receptor in self-detoxification.

Published in:

Amino Acids, 2017, v. 49, n. 12, p. 1999, doi. 10.1007/s00726-017-2435-0

By:

He, Liuqin;
Zhou, Xihong;
Huang, Niu;
Li, Huan;
Li, Tiejun;
Yao, Kang;
Tian, Yanan;
Hu, Chien-An;
Yin, Yulong

Publication type:

Article

The Sustained-Exposure Dexamethasone Formulation OTO-104 Offers Effective Protection against Cisplatin-Induced Hearing Loss.

Published in:

2016

By:

Fernandez, Rayne;
Harrop-Jones, Anne;
Xiaobo Wang;
Dellamary, Luis;
LeBel, Carl;
Piu, Fabrice;
Wang, Xiaobo

Publication type:

journal article

RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells.

Published in:

Biochemical Journal, 2020, v. 477, n. 18, p. 3583, doi. 10.1042/BCJ20200427

By:

Hao Hu;
Masahiko Negishi

Publication type:

Article

TIN-X: target importance and novelty explorer.

Published in:

Bioinformatics, 2017, v. 33, n. 16, p. 2601, doi. 10.1093/bioinformatics/btx200

By:

Cannon, Daniel C.;
Yang, Jeremy J.;
Mathias, Stephen L.;
Ursu, Oleg;
Mani, Subramani;
Waller, Anna;
Schürer, Stephan C.;
Jensen, Lars Juhl;
Sklar, Larry A.;
Bologa, Cristian G.;
Oprea, Tudor I.

Publication type:

Article

Prediction of nuclear export signals using weighted regular expressions (Wregex).

Published in:

Bioinformatics, 2014, v. 30, n. 9, p. 1220, doi. 10.1093/bioinformatics/btu016

By:

Prieto, Gorka;
Fullaondo, Asier;
Rodriguez, Jose A.

Publication type:

Article

Network predicting drug’s anatomical therapeutic chemical code.

Published in:

Bioinformatics, 2013, v. 29, n. 10, p. 1317, doi. 10.1093/bioinformatics/btt158

By:

Wang, Yong-Cui;
Chen, Shi-Long;
Deng, Nai-Yang;
Wang, Yong

Publication type:

Article

Drug–target interaction prediction by learning from local information and neighbors.

Published in:

Bioinformatics, 2013, v. 29, n. 2, p. 238, doi. 10.1093/bioinformatics/bts670

By:

Mei, Jian-Ping;
Kwoh, Chee-Keong;
Yang, Peng;
Li, Xiao-Li;
Zheng, Jie

Publication type:

Article

NURBS: a database of experimental and predicted nuclear receptor binding sites of mouse.

Published in:

Bioinformatics, 2013, v. 29, n. 2, p. 295, doi. 10.1093/bioinformatics/bts693

By:

Fang, Yaping;
Liu, Hui-Xin;
Zhang, Ning;
Guo, Grace L.;
Wan, Yu-Jui Yvonne;
Fang, Jianwen

Publication type:

Article

Inferring statin-induced gene regulatory relationships in primary human hepatocytes.

Published in:

Bioinformatics, 2011, v. 27, n. 18, p. 2473, doi. 10.1093/bioinformatics/btr416

By:

Schröder, Adrian;
Wollnik, Johannes;
Wrzodek, Clemens;
Dräger, Andreas;
Bonin, Michael;
Burk, Oliver;
Thomas, Maria;
Thasler, Wolfgang E.;
Zanger, Ulrich M.;
Zell, Andreas

Publication type:

Article

Prediction of drug-target interaction networks from the integration of chemical and genomic spaces.

Published in:

Bioinformatics, 2008, v. 24, n. 13, p. i232, doi. 10.1093/bioinformatics/btn162

By:

Yoshihiro Yamanishi;
Michihiro Araki;
Alex Gutteridge;
Wataru Honda;
Minoru Kanehisa

Publication type:

Article

Context-dependent clustering for dynamic cellular state modeling of microarray gene expression.

Published in:

Bioinformatics, 2007, v. 23, n. 22, p. 3039, doi. 10.1093/bioinformatics/btm457

By:

Shinsheng Yuan;
Ker-Chau Li

Publication type:

Article

STOP: searching for transcription factor motifs using gene expression.

Published in:

Bioinformatics, 2007, v. 23, n. 14, p. 1737, doi. 10.1093/bioinformatics/btm249

By:

Libi Hertzberg;
Shai Izraeli;
Eytan Domany

Publication type:

Article

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells.

Published in:

2010

By:

Glass, Christopher K.;
Saijo, Kaoru

Publication type:

journal article

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 5, p. 353, doi. 10.1038/nri2079

By:

O'Neill, Luke A. J.;
Bowie, Andrew G.

Publication type:

Article

Combinatorial roles of nuclear receptors in inflammation and immunity.

Published in:

2006

By:

Glass, Christopher K.;
Ogawa, Sumito

Publication type:

journal article

Macrophages: Orphan receptor finds a home.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 7, p. 514, doi. 10.1038/nri1140

By:

Buckland, Jenny

Publication type:

Article

Molecular genetics: DNA binding drives nuclear receptor architecture.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 8, p. 514, doi. 10.1038/nrg3789

By:

Lokody, Isabel

Publication type:

Article

The Nuclear Receptor COUP-TFII Regulates Amhr2 Gene Transcription via a GC-Rich Promoter Element in Mouse Leydig Cells.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 12, p. 2236, doi. 10.1210/js.2019-00266

By:

Mehanovic, Samir;
Mendoza-Villarroel, Raifish E;
Viger, Robert S;
Tremblay, Jacques J

Publication type:

Article

Glucocorticoid and Mineralocorticoid Receptors in the Brain: A Transcriptional Perspective.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 10, p. 1917, doi. 10.1210/js.2019-00158

By:

Koning, Anne-Sophie C A M;
Buurstede, Jacobus C;
Weert, Lisa T C M van;
Meijer, Onno C

Publication type:

Article

New Case of Thyroid Hormone Resistance a Caused by a Mutation of THRA/TRα1.

Published in:

Journal of the Endocrine Society, 2019, v. 3, n. 3, p. 665, doi. 10.1210/js.2019-00011

By:

Sun, Hui;
Wu, Haiying;
Xie, Rongrong;
Wang, Fengyun;
Chen, Ting;
Chen, Xiuli;
Wang, Xiaoyan;
Flamant, Frédéric;
Chen, Linqi

Publication type:

Article

Immunohistochemical expression of epidermal growth factor receptor: prognostic value in HER2 positive breast cancer.

Published in:

Journal of Immunoassay & Immunochemistry, 2025, v. 46, n. 3, p. 262, doi. 10.1080/15321819.2025.2475291

By:

Houcine, Yoldez;
Ben Salem, Hend;
El Fekih, Sirine;
Maaoui, Amal;
Driss, Maha

Publication type:

Article

Relationship between blood–brain barrier changes and drug metabolism under high-altitude hypoxia: obstacle or opportunity for drug transport?

Published in:

Drug Metabolism Reviews, 2023, v. 55, n. 1/2, p. 107, doi. 10.1080/03602532.2023.2180028

By:

Liu, Guiqin;
Bai, Xue;
Yang, Jianxin;
Duan, Yabin;
Zhu, Junbo;
Xiangyang, Li

Publication type:

Article

Transcriptional regulation of CYP3A4 by nuclear receptors in human hepatocytes under hypoxia.

Published in:

Drug Metabolism Reviews, 2020, v. 52, n. 2, p. 225, doi. 10.1080/03602532.2020.1733004

By:

Yuan, Xuechun;
Lu, Hui;
Zhao, Anpeng;
Ding, Yidan;
Min, Qiong;
Wang, Rong

Publication type:

Article

Regulation of brain drug metabolizing enzymes and transporters by nuclear receptors.

Published in:

Drug Metabolism Reviews, 2018, v. 50, n. 4, p. 407, doi. 10.1080/03602532.2018.1554673

By:

Xu, Dan;
Huang, Songqiang;
Wang, Hui;
Xie, Wen

Publication type:

Article

Sulfotransferase genes: Regulation by nuclear receptors in response to xeno/endo-biotics.

Published in:

Drug Metabolism Reviews, 2013, v. 45, n. 4, p. 441, doi. 10.3109/03602532.2013.835630

By:

Kodama, Susumu;
Negishi, Masahiko

Publication type:

Article

Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier.

Published in:

Drug Metabolism Reviews, 2014, v. 46, n. 1, p. 19, doi. 10.3109/03602532.2013.835819

By:

Pavek, Petr;
Smutny, Tomas

Publication type:

Article

Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 4, p. 621, doi. 10.3109/03602532.2010.484462

By:

Dvorak, Zdenek;
Pavek, Peotr

Publication type:

Article

Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.

Published in:

Drug Metabolism Reviews, 2011, v. 43, n. 1, p. 27, doi. 10.3109/03602532.2010.512294

By:

Jiang, Xi-Ling;
Gonzalez, Frank J.;
Yu, Ai-Ming

Publication type:

Article

UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor–inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 5, doi. 10.3109/03602530903205492

By:

Bock, Karl W.;
Bock-Hennig, Barbara S.

Publication type:

Article

Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 106, doi. 10.3109/03602530903219220

By:

Verreault, Mélanie;
Kaeding, Jenny;
Caron, Patrick;
Trottier, Jocelyn;
Grosse, Laurent;
Houssin, Élise;
Pâquet, Sophie;
Perreault, Martin;
Barbier, Olivier

Publication type:

Article

PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity.

Published in:

Drug Metabolism Reviews, 2006, v. 38, n. 3, p. 515, doi. 10.1080/03602530600786232

By:

Stanley, Lesley A.;
Horsburgh, Brian C.;
Ross, Jillian;
Scheer, Nico;
Roland Wolf, C.

Publication type:

Article