Title: Antiviral and Antibacterial Polyurethanes of Various Modalities.
Authors: Park, Daewon; Larson, Alyssa; Klibanov, Alexander; Wang, Yadong
Abstract: We have prepared and characterized a new polyurethane-based antimicrobial material, N, N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
Subjects: ANTIVIRAL agents; ANTIBACTERIAL agents; POLYURETHANES; NANOPARTICLES; NANOFIBERS; STAPHYLOCOCCUS aureus; ESCHERICHIA coli
Publication: Applied Biochemistry & Biotechnology, 2013, Vol 169, Issue 4, p1134
ISSN: 0273-2289
Publication type: Academic Journal
DOI: 10.1007/s12010-012-9999-7

Antiviral and Antibacterial Polyurethanes of Various Modalities.

Park, Daewon; Larson, Alyssa; Klibanov, Alexander; Wang, Yadong