Title: Practical Aspects of Hydrophobic Polycationic Bactericidal “Paints”.
Authors: Koushik Mukherjee; Jaime Rivera; Alexander Klibanov
Abstract: Abstract We previously discovered that coating solid surfaces with long-chained linear N-dodecyl,N-methyl-polyethylenimine makes them bactericidal and virucidal. In the present study, focusing on the use of this microbicidal paint to kill airborne Escherichia coli and Staphylococcus aureus, we have systematically investigated the dependence of this effect on the concentration and mode of application of the hydrophobic polycation, the number of coats, the nature of the solvent, and the presence of a dye in such paint. In addition, the latter’s ability to be regenerated after use, stability upon repeated washings, and mammalian toxicity has been evaluated.
Subjects: BACTERICIDES; ESCHERICHIA coli disease prevention; STAPHYLOCOCCUS aureus infections; HYDROPHOBIC surfaces; SURFACE chemistry; POLYELECTROLYTES; ENTEROBACTERIACEAE; PREVENTION
Publication: Applied Biochemistry & Biotechnology, 2008, Vol 151, Issue 1, p61
ISSN: 0273-2289
Publication type: Academic Journal
DOI: 10.1007/s12010-008-8151-1

Practical Aspects of Hydrophobic Polycationic Bactericidal “Paints”.

Koushik Mukherjee; Jaime Rivera; Alexander Klibanov