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- Title
Practical Aspects of Hydrophobic Polycationic Bactericidal “Paints”.
- Authors
Koushik Mukherjee; Jaime Rivera; Alexander Klibanov
- Abstract
Abstract We previously discovered that coating solid surfaces with long-chained linear N-dodecyl,N-methyl-polyethylenimine makes them bactericidal and virucidal. In the present study, focusing on the use of this microbicidal paint to kill airborne Escherichia coli and Staphylococcus aureus, we have systematically investigated the dependence of this effect on the concentration and mode of application of the hydrophobic polycation, the number of coats, the nature of the solvent, and the presence of a dye in such paint. In addition, the latter’s ability to be regenerated after use, stability upon repeated washings, and mammalian toxicity has been evaluated.
- Subjects
BACTERICIDES; ESCHERICHIA coli disease prevention; STAPHYLOCOCCUS aureus infections; HYDROPHOBIC surfaces; SURFACE chemistry; POLYELECTROLYTES; ENTEROBACTERIACEAE; PREVENTION
- Publication
Applied Biochemistry & Biotechnology, 2008, Vol 151, Issue 1, p61
- ISSN
0273-2289
- Publication type
Academic Journal
- DOI
10.1007/s12010-008-8151-1