Works matching DE "LIVER proteins"

Results: 483

Procalcitonin as a Predictive Marker of Incident Liver Disease.

Published in:

Liver International, 2025, v. 45, n. 6, p. 1, doi. 10.1111/liv.70132

By:

Finnberg‐Kim, Amanda;
Pihlsgård, Mats;
Önnerhag, Kristina;
Melander, Olle;
Enhörning, Sofia

Publication type:

Article

Preclinical Research on Cinnamic Acid Derivatives for the Prevention of Liver Damage: Promising Therapies for Liver Diseases.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1094, doi. 10.3390/biomedicines13051094

By:

Aldaba-Muruato, Liseth Rubí;
Escalante-Hipólito, Brayan;
Alarcón-López, Aldo Yoshio;
Martínez-Soriano, Pablo A.;
Angeles, Enrique;
Macías-Pérez, José Roberto

Publication type:

Article

Formation of S-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction.

Published in:

Amino Acids, 2013, v. 44, n. 2, p. 361, doi. 10.1007/s00726-012-1339-2

By:

Naudí, Alba;
Jové, Mariona;
Cacabelos, Daniel;
Ayala, Victoria;
Cabre, Rosanna;
Caro, Pilar;
Gomez, José;
Portero-Otín, Manuel;
Barja, Gustavo;
Pamplona, Reinald

Publication type:

Article

Diagnostic Value of Serum Golgi Protein 73 for Liver Fibrosis: A Systematic Review and Meta-Analysis.

Published in:

Digestive Diseases, 2023, v. 41, n. 4, p. 622, doi. 10.1159/000529815

By:

Peng, Se;
Wu, Qingrong;
Huang, Xiaoting;
He, Xuehua;
Li, Zhong;
Xu, Jianfeng;
Wang, Lei;
Zhuang, Jialing

Publication type:

Article

Characterization of the structural determinants of the ubiquitin-dependent proteasomal degradation of human hepatic tryptophan 2,3-dioxygenase.

Published in:

Biochemical Journal, 2021, v. 478, n. 10, p. 1999, doi. 10.1042/BCJ20210213

By:

Yi Liu;
Sung-Mi Kim;
YongQiang Wang;
Karkashon, Shay;
Lewis-Ballester, Ariel;
Syun-Ru Yeh;
Correia, Maria Almira

Publication type:

Article

功效性米粉对高脂诱导小鼠血脂的影响.

Published in:

Food Research & Development, 2025, v. 46, n. 9, p. 7, doi. 10.12161/j.issn.1005‐6521.2025.09.002

By:

熊志伟;
张文君;
陶悦;
韩慧缃;
梁伟

Publication type:

Article

超声波辅助 pH 偏移处理对猪肝蛋白结构及乳化特性的影响.

Published in:

Food Research & Development, 2023, v. 44, n. 5, p. 89, doi. 10.12161/j.issn.1005-6521.2023.05.014

By:

陆今明;
彭松林;
杨凯麟;
耿宏庆;
尚永彪

Publication type:

Article

苦荞活性肽 P3 对链脲佐菌素诱导的糖尿病小鼠的改善作用研究.

Published in:

Food Research & Development, 2022, v. 43, n. 15, p. 48, doi. 10.12161/j.issn.1005-6521.2022.15.007

By:

左婕;
费烨;
李佳慧;
肖怡;
王筑婷;
许庆忠;
李红梅

Publication type:

Article

橄榄叶中多酚含量的测定及其抗辐射作用研究.

Published in:

Food Research & Development, 2021, v. 42, n. 6, p. 44, doi. 10.12161/j.issn.1005-6521.2021.06.009

By:

孙美君;
孔杭如;
赵珈莹;
张伊瑾;
林丽颖;
郭东北;
李蕾

Publication type:

Article

Combined treatment with FABP4 inhibitor ameliorates rosiglitazone‐induced liver steatosis in obese diabetic db/db mice.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2021, v. 129, n. 3, p. 173, doi. 10.1111/bcpt.13621

By:

Chen, Meng‐Ting;
Huang, Jun‐Shang;
Gao, Ding‐Ding;
Li, Ying‐Xia;
Wang, He‐Yao

Publication type:

Article

Aqueous Extract from Leaves of Citrus unshiu Attenuates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model of Systemic Inflammation.

Published in:

Plants (2223-7747), 2021, v. 10, n. 8, p. 1708, doi. 10.3390/plants10081708

By:

Nishi, Kosuke;
Ito, Takako;
Kadota, Ayumu;
Ishida, Momoko;
Nishiwaki, Hisashi;
Fukuda, Naohiro;
Kanamoto, Naoaki;
Nagata, Yoko;
Sugahara, Takuya

Publication type:

Article

Biochemical Parameters and Protein Oxidation Relationship for Hepatitis C Patients and Healthy Ones.

Published in:

Pakistan Journal of Scientific & Industrial Research Series B: Biological Sciences, 2022, v. 65, n. 1, p. 50

By:

Khitab, Umar;
Ullah, Ikram;
Zaman, Ali;
Shakeebullah;
Malik, Muhammad Inamullah;
Khan, Muhammad Shoaib;
Ullah, Naimat;
Muhammad, Khalid;
Malik, Shumaila Noreen;
Jilani, Ghulam

Publication type:

Article

大蒜辣素缓解 CCl<sub>4</sub> 致小鼠急性肝损伤的作用研究.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2023, v. 46, n. 3, p. 530, doi. 10.7685/jnau.202202020

By:

龚倩梅;
刘永仕;
袁何玲;
吕茜;
王晓明;
黄金虎;
王丽平

Publication type:

Article

Fermented Rice Bran Mitigated the Syndromes of Type 2 Diabetes in KK- A y Mice Model.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 11, p. 614, doi. 10.3390/metabo14110614

By:

Agista, Afifah Zahra;
Kato, Ami;
Goto, Tomoko;
Koseki, Takuya;
Oikawa, Akira;
Ohsaki, Yusuke;
Yamaki, Michiko;
Yeh, Chiu-Li;
Yang, Suh-Ching;
Ardiansyah;
Budijanto, Slamet;
Komai, Michio;
Shirakawa, Hitoshi

Publication type:

Article

Accumulation of Non-Pathological Liver Fat Is Associated with the Loss of Glyoxalase I Activity in Humans.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 4, p. 209, doi. 10.3390/metabo14040209

By:

Peter, Andreas;
Schleicher, Erwin;
Kliemank, Elisabeth;
Szendroedi, Julia;
Königsrainer, Alfred;
Häring, Hans-Ulrich;
Nawroth, Peter P.;
Fleming, Thomas

Publication type:

Article

Structural Identification of Zotarolimus (ABT-578) Metabolites Generated by Human Liver Microsomes Using Ion-Trap and High-Resolution Time-of-Flight Mass Spectrometry in Combination with the Analysis of Fragmentation Patterns.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 10, p. 1093, doi. 10.3390/metabo13101093

By:

Shokati, Touraj;
Drake, Seth H.;
Zhao, Wanzhu;
Klawitter, Jost;
Klawitter, Jelena;
Christians, Uwe

Publication type:

Article

High-Intensity Interval Training Induces Protein Lactylation in Different Tissues of Mice with Specificity and Time Dependence.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 5, p. 647, doi. 10.3390/metabo13050647

By:

Huang, Wenhua;
Su, Jie;
Chen, Xuefei;
Li, Yanjun;
Xing, Zheng;
Guo, Lanlan;
Li, Shitian;
Zhang, Jing

Publication type:

Article

Expression of STING in Women with Morbid Obesity and Nonalcoholic Fatty Liver Disease.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 496, doi. 10.3390/metabo13040496

By:

Bertran, Laia;
Adalid, Laia;
Vilaró-Blay, Mercè;
Barrientos-Riosalido, Andrea;
Aguilar, Carmen;
Martínez, Salomé;
Sabench, Fàtima;
del Castillo, Daniel;
Porras, José Antonio;
Alibalic, Ajla;
Richart, Cristóbal;
Auguet, Teresa

Publication type:

Article

Liver Fetuin-A at Initiation of Insulin Resistance.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 11, p. 1023, doi. 10.3390/metabo12111023

By:

Lanthier, Nicolas;
Lebrun, Valérie;
Molendi-Coste, Olivier;
van Rooijen, Nico;
Leclercq, Isabelle A.

Publication type:

Article

Fatty Acid-Binding Proteins in Psoriasis—A Review.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 9, p. 833, doi. 10.3390/metabo12090833

By:

Nowowiejska, Julia;
Baran, Anna;
Flisiak, Iwona

Publication type:

Article

Effect of Physical Exercise and Genetic Background on Glucose Homeostasis and Liver/Muscle Proteomes in Mice.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/metabo12020117

By:

Fernandes, Mileni S.;
Sabino-Arias, Isabela T.;
Dionizio, Aline;
Fabricio, Mayara F.;
Trevizol, Juliana S.;
Martini, Tatiana;
Azevedo, Liane B.;
Valentine, Ruth A.;
Maguire, Anne;
Zohoori, Fatemeh V.;
L. Amaral, Sandra;
Buzalaf, Marília A. R.

Publication type:

Article

Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality.

Published in:

Life (2075-1729), 2023, v. 13, n. 8, p. 1745, doi. 10.3390/life13081745

By:

Gagliardi, Anna;
Bajraktari-Sylejmani, Gzona;
Barocelli, Elisabetta;
Weiss, Johanna;
Rigalli, Juan Pablo

Publication type:

Article

Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.601716

By:

Xu, Qiushi;
Fan, Yunhui;
Loor, Juan J.;
Liang, Yusheng;
Sun, Xudong;
Jia, Hongdou;
Zhao, Chenxu;
Xu, Chuang

Publication type:

Article

Effects of Dietary Aflatoxin B1 on Hybrid Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) Growth, Intestinal Health, and Muscle Quality.

Published in:

Aquaculture Nutrition, 2024, v. 2024, p. 1, doi. 10.1155/2024/3920254

By:

Liu, Hao;
Xie, Ruitao;
Huang, Weibin;
Yang, Yuanzhi;
Zhou, Menglong;
Lu, Baiquan;
Li, Biao;
Tan, Beiping;
Dong, Xiaohui

Publication type:

Article

Comparative Study on the Effects of Four Plant Protein Sources on the Liver and Intestinal Health of Largemouth Bass, Micropterus salmoides.

Published in:

Aquaculture Nutrition, 2024, p. 1, doi. 10.1155/2024/6337005

By:

Yao, Shibin;
Li, Wenjian;
Cai, Chunfang;
Wang, Chengrui;
Kang, Jia;
Hu, Honglin;
Wu, Ping;
Cao, Xiamin;
Ye, Yuantu

Publication type:

Article

Amino Acid Metabolism in Gilthead Seabream Is Affected by the Dietary Protein to Energy Ratios.

Published in:

Aquaculture Nutrition, 2022, p. 1, doi. 10.1155/2022/8230704

By:

Teodósio, Rita;
Aragão, Cláudia;
Conceição, Luís E. C.;
Dias, Jorge;
Engrola, Sofia

Publication type:

Article

Effects of dietary replacement of fish oil with soybean oil on the growth performance, plasma components, fatty acid composition and lipid metabolism of groupers Epinephelus coioides.

Published in:

Aquaculture Nutrition, 2021, v. 27, n. 5, p. 1494, doi. 10.1111/anu.13292

By:

He, Lingyun;
Qin, Yingmei;
Wang, Yanfei;
Li, Dong;
Chen, Weijun;
Ye, Jidan

Publication type:

Article

Causal Association Between Circulating Inflammatory Proteins and Autoimmune Liver Disease: a Bidirectional Two-Sample Mendelian Randomization Study.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 279, doi. 10.2147/ITT.S508140

By:

Leng, Lina;
Li, Ying;
Xu, Tao;
Shen, Jingfang;
Li, Lianju;
Li, Xiaoli

Publication type:

Article

Subacute exposure to apigenin induces changes in protein synthesis in the liver of Swiss mice.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1576310

By:

Jarosz, Łukasz S.;
Socała, Katarzyna;
Michalak, Katarzyna;
Bulak, Kamila;
Ciszewski, Artur;
Marek, Agnieszka;
Grądzki, Zbigniew;
Wlaź, Piotr;
Kowalczuk-Vasilev, Edyta;
Rysiak, Anna

Publication type:

Article

Restoration of mRNA Expression of Solute Carrier Proteins in Liver of Diet-Induced Obese Mice by Metformin.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.720784

By:

Le, Jiamei;
Fu, Yi;
Han, Qiuqin;
Wei, Xindong;
Ji, Houlin;
Chen, Yifan;
Wang, Qiuying;
Pi, Peixian;
Li, Jilei;
Lin, Xinjie;
Zhang, Xiaoying;
Zhang, Yong;
Ye, Jianping

Publication type:

Article

Liver Proteome Profile of Growth Restricted and Appropriately Grown Newborn Wistar Rats Associated With Maternal Undernutrition.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.684220

By:

Sarli, Polyxeni-Maria;
Manousopoulou, Antigoni;
Efthymiou, Elias;
Zouridis, Andreas;
Potiris, Anastasios;
Pervanidou, Panagiota;
Panoulis, Konstantinos;
Vlahos, Nikolaos;
Deligeoroglou, Efthymios;
Garbis, Spiros D.;
Eleftheriades, Makarios

Publication type:

Article

The Protective Role of the Carbohydrate Response Element Binding Protein in the Liver: The Metabolite Perspective.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.594041

By:

Agius, Loranne;
Chachra, Shruti S.;
Ford, Brian E.

Publication type:

Article

Співвідношення редокс-форм убіхінону в мітохондріях печінки щурів за умов різної забезпеченості раціону нутрієнтами

Published in:

Physiological Journal / Fiziologichnyi Zhurnal, 2020, v. 66, n. 6, p. 82

By:

Волощук, О. М.;
Копильчук, Г. П.;
Урсатий, М. С.

Publication type:

Article

Two Novel FAM20C Variants in a Family with Raine Syndrome.

Published in:

Genes, 2020, v. 11, n. 2, p. 222, doi. 10.3390/genes11020222

By:

Hernández-Zavala, Araceli;
Cortés-Camacho, Fernando;
Palma-Lara, Icela;
Godínez-Aguilar, Ricardo;
Espinosa, Ana María;
Pérez-Durán, Javier;
Villanueva-Ocampo, Patricia;
Ugarte-Briones, Carlos;
Serrano-Bello, Carlos Alberto;
Sánchez-Santiago, Paula Jesús;
Bonilla-Delgado, José;
Yáñez-López, Marco Antonio;
Victoria-Acosta, Georgina;
López-Ornelas, Adolfo;
García Alonso-Themann, Patricia;
Moreno, José;
Palacios-Reyes, Carmen

Publication type:

Article

Comparison of Bax and Caspase-3 Protein Expression in Liver Cells following UVB Irradiation for 7 days and Treatment of Pimpinella alpina Molk during 7 and 15 days.

Published in:

Bangladesh Journal of Medical Science, 2020, v. 19, n. 2, p. 296, doi. 10.3329/bjms.v19i2.45011

By:

Widayati, Eni;
Nasihun, Taufiqurrachman;
Savitri, Azizah Hikma;
Tyagita, Nurina

Publication type:

Article

Preparation and evaluation of camptothecin granules for molluscacidal activity.

Published in:

Allelopathy Journal, 2017, v. 42, n. 1, p. 145, doi. 10.26651/2017-42-1-1112

By:

Yang, H. S.;
Sun, C. X.;
Li, T.;
Li, G. J.;
Ke, W. S.;
Sun, Q. X.

Publication type:

Article

The Effect of Usnic Acid and Alphalypoic Acid on Changes Occurring in Cell Mitogenic Activity Proteins in Liver and Kidney Tissue of Cadmium Toxicity-Supplied Rats.

Published in:

Biology Bulletin, 2023, v. 50, p. S436, doi. 10.1134/S1062359023603099

By:

Tubanur Aslan Engin;
Nadide Nabil Kamiloglu

Publication type:

Article

Low-dose lipopolysaccharide exposure can increase in vivo bilirubin production rates in newborn mice.

Published in:

2020

By:

Iwatani, Sota;
Jacobsen, Danielle R.;
Wong, Ronald J.;
Stevenson, David K.

Publication type:

journal article

Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p-nitrophenol.

Published in:

Xenobiotica, 2023, v. 53, n. 10/11, p. 573, doi. 10.1080/00498254.2023.2280996

By:

Ushirozako, Genki;
Murayama, Norie;
Tsukiyama-Kohara, Kyoko;
Yamazaki, Hiroshi;
Uno, Yasuhiro

Publication type:

Article

Hepatoprotective Effect of Grape Seed and Skin Extract Against Lithium Exposure Examined by the Window of Proteomics.

Published in:

Dose-Response, 2022, v. 20, n. 4, p. 1, doi. 10.1177/15593258221141585

By:

Mezni, Ali;
Khazri, Olfa;
Jarnier, Frédérique;
Hardouin, Julie;
Limam, Ferid;
Jouenne, Thierry;
Aouani, Ezzeddine;
Cosette, Pascal

Publication type:

Article

Potential Anticancer Activity of Alcea rosea and Molecular Docking of Selected Target Proteins in Liver Cancer Cells.

Published in:

International Journal of Morphology, 2024, v. 42, n. 6, p. 1746, doi. 10.4067/s0717-95022024000601746

By:

Abutaha, Nael;
Wadaan, Mohamed A.;
Alghamdi, Raed Ahmad;
Al-Mekhlafi, Fahd A.

Publication type:

Article

Exploring the Anti-Cancer Properties of Nasturtium officinale L. via the HOTAIR/miR-124/Notch1 Pathway in Rat Hepatocellular Carcinoma: An Investigation Using Biochemical, Molecular, Immunohistochemical, and Histopathological Methods.

Published in:

International Journal of Morphology, 2024, v. 42, n. 5, p. 1361, doi. 10.4067/s0717-95022024000501361

By:

Huichao Feng;
Sheng Zheng;
Juan Yang;
Xiaozhou Mao;
Tao Liu;
Qiuxin Zhang;
Yaqin Chen

Publication type:

Article

Ablation of Mouse Selenium-Binding Protein 1 and 2 Elevates LDL by Disruption of Cholesterol Efflux and Lipid Metabolism †.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 7, p. 3363, doi. 10.3390/ijms26073363

By:

Zhao, Shuangli;
Song, Yingxia;
Nakashima, Yuko;
Zou, Xing;
Koga, Takayuki;
Ishida, Takumi;
Li, Renshi;
Hirota, Yuko;
Tanaka, Yoshitaka;
Ishii, Yuji

Publication type:

Article

Protective Vaccination of Mice Against Blood-Stage Malaria Impacts Hepatic Expression of Genes Encoding Acute-Phase Proteins and IL-6 Family Members.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 7, p. 3173, doi. 10.3390/ijms26073173

By:

Wunderlich, Frank;
Gerovska, Daniela;
Delic, Denis;
Araúzo-Bravo, Marcos J.

Publication type:

Article

Poria cocos -Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 2253, doi. 10.3390/ijms26052253

By:

Wang, Tao;
Zhao, Jun;
Li, Qiu-Yi;
Yang, Hui-Qiong;
Li, Min;
Duan, Rong;
Zhang, Mei;
Qi, Yan;
Yu, Jie;
Yang, Xing-Xin

Publication type:

Article

Molecular Mechanism of Vine Tea Dihydromyricetin Extract on Alleviating Glucolipid Metabolism Disorder in db/db Mice: Based on Liver RNA-Seq and TLR4/MyD88/NF-κB Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 2169, doi. 10.3390/ijms26052169

By:

Zhou, Xixin;
Liu, Xin;
Yi, Yuhang;
Chen, Shiyun;
Zhang, Yi;
Fan, Wei;
Lv, Chenghao;
Qin, Si

Publication type:

Article

Hepatocyte expressed chemerin-156 does not protect from experimental non-alcoholic steatohepatitis.

Published in:

Molecular & Cellular Biochemistry, 2022, v. 477, n. 8, p. 2059, doi. 10.1007/s11010-022-04430-3

By:

Pohl, Rebekka;
Eichelberger, Laura;
Feder, Susanne;
Haberl, Elisabeth M.;
Rein-Fischboeck, Lisa;
McMullen, Nichole;
Sinal, Christopher J.;
Bruckmann, Astrid;
Weiss, Thomas S.;
Beck, Michael;
Höring, Marcus;
Krautbauer, Sabrina;
Liebisch, Gerhard;
Wiest, Reiner;
Wanninger, Josef;
Buechler, Christa

Publication type:

Article

Differential production of insulin-like growth factor-binding proteins in liver fibrosis progression.

Published in:

Molecular & Cellular Biochemistry, 2020, v. 469, n. 1/2, p. 65, doi. 10.1007/s11010-020-03728-4

By:

Martínez-Castillo, Moisés;
Rosique-Oramas, Dorothy;
Medina-Avila, Zaira;
Pérez-Hernández, José Luis;
Higuera-De la Tijera, Fatima;
Santana-Vargas, Daniel;
Montalvo-Jave, Eduardo Esteban;
Sanchez-Avila, Francico;
Torre, Aldo;
Kershenobich, David;
Gutierrez-Reyes, Gabriela

Publication type:

Article

Diabetes mellitus aggravates ranolazine-induced ECG changes in rats.

Published in:

Journal of Interventional Cardiac Electrophysiology, 2022, v. 63, n. 2, p. 379, doi. 10.1007/s10840-021-01016-9

By:

Mashayekhi-Sardoo, Habibeh;
Mohammadpour, Amir Hooshang;
Mehri, Soghra;
Kamali, Hossein;
Sahebkar, Amirhossein;
Imenshahidi, Mohsen

Publication type:

Article

NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01088-7

By:

Yao, Chao-Yan;
Tao, Hang-Tian;
He, Jin-Jin;
Zhu, Feng-Yi;
Xie, Cui-Qing;
Cheng, Yu-Na;
Li, Ji-Qin;
Liu, Zhuang-Zhuang;
Hou, Chun-Yu;
Liu, Xue-Li;
Fan, Yong-Li;
Fang, Dong;
Lv, Xin-Rui

Publication type:

Article