Works matching DE "CYCLIN-dependent kinases"
Results: 3898
CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 396, doi. 10.1038/nsmb.3000
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- Article
A bumpy road for RNA polymerase II.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 353, doi. 10.1038/nsmb.3020
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- Article
Multisite phosphorylation networks as signal processors for Cdk1.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1415, doi. 10.1038/nsmb.2706
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- Article
Cks confers specificity to phosphorylation-dependent CDK signaling pathways.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1407, doi. 10.1038/nsmb.2707
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- Article
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1108, doi. 10.1038/nsmb.2399
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- Article
Crystal structure of human CDC7 kinase in complex with its activator DBF4.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1101, doi. 10.1038/nsmb.2404
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- Article
Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 246, doi. 10.1038/nsmb.2212
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- Article
Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1065, doi. 10.1038/nsmb.1878
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- Article
CDK8 is a positive regulator of transcriptional elongation within the serum response network.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 194, doi. 10.1038/nsmb.1752
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- Article
Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV.
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- Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1287, doi. 10.1038/nsmb.1513
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- Article
CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage.
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- Nature Structural & Molecular Biology, 2006, v. 13, n. 10, p. 908, doi. 10.1038/nsmb1139
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- Article
Research Highlights.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 9, p. 741, doi. 10.1038/nsmb0905-741
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- Article
p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding.
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- Nature Structural & Molecular Biology, 2004, v. 11, n. 4, p. 358, doi. 10.1038/nsmb746
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- Publication type:
- Article
Ganaxolone in seizures associated with cyclin-dependent kinase-like 5 deficiency disorder: a profile of its use in the USA.
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- Drugs & Therapy Perspectives, 2023, v. 39, n. 3, p. 81, doi. 10.1007/s40267-022-00976-w
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- Article
Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition.
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- 2018
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- Abstract
Chemically induced premature chromosome condensation in short-term cultured human peripheral lymphocytes: applications to biodosimetry.
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- Biotechnic & Histochemistry, 2007, v. 82, n. 1, p. 29, doi. 10.1080/10520290701257153
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- Article
Electron microscopy evidence that cytoplasmic localization of the p16 INK4A "nuclear" cyclin-dependent kinase inhibitor (CKI) in tumor cells is specific and not an artifact. A study in non-small cell lung carcinomas.
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- Biotechnic & Histochemistry, 2004, v. 79, n. 1, p. 5, doi. 10.1080/10520290310001659466
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- Article
Cyclin D1 (G870A) polymorphism and risk of cervix cancer: a case control study in north Indian population.
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- Molecular & Cellular Biochemistry, 2008, v. 315, n. 1/2, p. 151, doi. 10.1007/s11010-008-9799-0
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- Article
The proximal GC-rich region of p16<sup>INK4a</sup> gene promoter plays a role in its transcriptional regulation.
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- Molecular & Cellular Biochemistry, 2007, v. 301, n. 1/2, p. 259, doi. 10.1007/s11010-007-9427-4
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- Article
Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27<sup>Kip1</sup> induction.
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- Molecular & Cellular Biochemistry, 2007, v. 301, n. 1/2, p. 115, doi. 10.1007/s11010-006-9402-5
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- Publication type:
- Article
A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery.
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- Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 6, p. 671, doi. 10.1007/s10822-018-0120-3
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- Article
Protein–ligand docking with multiple flexible side chains.
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- Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 9, p. 673, doi. 10.1007/s10822-007-9148-5
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- Publication type:
- Article
Molecular dynamics simulations on the inhibition of Cyclin-Dependent Kinases 2 and 5 in the presence of activators.
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- Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 6, p. 395, doi. 10.1007/s10822-006-9081-z
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- Publication type:
- Article
Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors.
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- Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 2, p. 111, doi. 10.1007/s10822-005-1778-x
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- Publication type:
- Article
Anti-HER2 therapy in metastatic breast cancer: many choices and future directions.
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- Cancer & Metastasis Reviews, 2022, v. 41, n. 1, p. 193, doi. 10.1007/s10555-022-10021-x
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- Publication type:
- Article
Cyclin-dependent kinase inhibitors in head and neck cancer and glioblastoma—backbone or add-on in immune-oncology?
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- Cancer & Metastasis Reviews, 2021, v. 40, n. 1, p. 153, doi. 10.1007/s10555-020-09940-4
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- Article
CDK7 inhibitors as anticancer drugs.
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- Cancer & Metastasis Reviews, 2020, v. 39, n. 3, p. 805, doi. 10.1007/s10555-020-09885-8
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- Article
Cyclin dependent kinases and their role in regulation of plant cell cycle.
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- Biologia Plantarum, 2011, v. 55, n. 2, p. 201, doi. 10.1007/s10535-011-0031-9
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- Article
Chondrocyte p21(WAF1/CIP1) expression is increased by dexamethasone but does not contribute to dexamethasone-induced growth retardation in vivo.
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- 2009
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- Publication type:
- journal article
Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancer.
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- World Journal of Urology, 2024, v. 42, n. 1, p. 1, doi. 10.1007/s00345-024-05188-7
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- Publication type:
- Article
Up-regulation of cell cycle regulatory genes after renal ischemia/reperfusion: differential expression of p16<sup>(INK4a)</sup>, p21<sup>(WAF1/CIP1)</sup> and p27<sup>(Kip1)</sup> cyclin-dependent kinase inhibitor genes depending on reperfusion time.
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- Transplant International, 2006, v. 19, n. 1, p. 72, doi. 10.1111/j.1432-2277.2005.00227.x
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- Article
Increased expression of p21 (WAF1/CIP1) cyclin-dependent kinase (CDK) inhibitor gene in chronic allograft nephropathy correlates with the number of acute rejection episodes.
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- Transplant International, 2003, v. 16, n. 8, p. 502, doi. 10.1007/s00147-003-0587-1
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- Article
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis.
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- European Journal of Clinical Pharmacology, 2024, v. 80, n. 12, p. 1893, doi. 10.1007/s00228-024-03757-8
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- Article
Quantitative evaluation of the efficacy and safety profiles of two types of targeted inhibitors combined with endocrine therapy in ER+/HER2− metastatic breast cancer.
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- European Journal of Clinical Pharmacology, 2024, v. 80, n. 9, p. 1387, doi. 10.1007/s00228-024-03715-4
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- Article
The effect of concomitant use of proton pump inhibitors with CDK 4/6 inhibitors on survival in metastatic breast cancer.
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- European Journal of Clinical Pharmacology, 2023, v. 79, n. 2, p. 243, doi. 10.1007/s00228-022-03435-7
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- Article
Early life infection alters adult BALB/c hippocampal gene expression in a sex specific manner.
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- Stress: The International Journal on the Biology of Stress, 2011, v. 14, n. 3, p. 247, doi. 10.3109/10253890.2010.532576
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- Article
Charcot-Marie-Tooth causing HSPB1 mutations increase Cdk5-mediated phosphorylation of neurofilaments.
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- Acta Neuropathologica, 2013, v. 126, n. 1, p. 93, doi. 10.1007/s00401-013-1133-6
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- Article
Role of cdk4, p16, and Rb Expression in the Prognosis of Bronchioloalveolar Carcinomas.
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- Respiration, 2005, v. 72, n. 1, p. 68, doi. 10.1159/000083403
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- Article
Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
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- Nature, 2015, v. 526, n. 7572, p. 273, doi. 10.1038/nature14904
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- Article
Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication.
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- Nature, 2015, v. 523, n. 7559, p. 236, doi. 10.1038/nature14473
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- Article
Regulated eukaryotic DNA replication origin firing with purified proteins.
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- Nature, 2015, v. 519, n. 7544, p. 431, doi. 10.1038/nature14285
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- Article
An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ.
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- Nature, 2015, v. 517, n. 7534, p. 391, doi. 10.1038/nature13887
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- Article
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
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- Nature, 2014, v. 511, n. 7511, p. 616, doi. 10.1038/nature13393
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- Article
Cyclin Dl-Cdk4 controls glucose metabolism independently of cell cycle progression.
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- Nature, 2014, v. 510, n. 7506, p. 547, doi. 10.1038/nature13267
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- Article
Meis1 regulates postnatal cardiomyocyte cell cycle arrest.
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- Nature, 2013, v. 497, n. 7448, p. 249, doi. 10.1038/nature12054
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- Article
ATPase-dependent quality control of DNA replication origin licensing.
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- Nature, 2013, v. 495, n. 7441, p. 339, doi. 10.1038/nature11920
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- Article
Neuroscience: Memory and the single molecule.
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- Nature, 2013, v. 493, n. 7432, p. 312, doi. 10.1038/nature11850
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- Article
Cell cycle: A division duet.
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- Nature, 2012, v. 481, n. 7381, p. 273, doi. 10.1038/nature10828
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- Article
Antidiabetic actions of a non-agonist PPAR? ligand blocking Cdk5-mediated phosphorylation.
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- Nature, 2011, v. 477, n. 7365, p. 477, doi. 10.1038/nature10383
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- Article
DNA repair: Cyclin D1 multitasks.
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- Nature, 2011, v. 474, n. 7350, p. 171, doi. 10.1038/474171a
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- Article