Works matching IS 07248741 AND DT 2017 AND VI 34 AND IP 12

Results: 39

Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2477, doi. 10.1007/s11095-017-2172-9

By:

Nickel, Sabrina;
Selo, Mohammed;
Fallack, Juliane;
Clerkin, Caoimhe;
Huwer, Hanno;
Schneider-Daum, Nicole;
Lehr, Claus-Michael;
Ehrhardt, Carsten

Publication type:

Article

Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2466, doi. 10.1007/s11095-017-2176-5

By:

Hoffman, Ewelina;
Patel, Aateka;
Ball, Doug;
Klapwijk, Jan;
Millar, Val;
Kumar, Abhinav;
Martin, Abigail;
Mahendran, Rhamiya;
Dailey, Lea;
Forbes, Ben;
Hutter, Victoria

Publication type:

Article

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2517, doi. 10.1007/s11095-017-2190-7

By:

Morris, Christopher;
Aljayyoussi, Ghaith;
Mansour, Omar;
Griffiths, Peter;
Gumbleton, Mark

Publication type:

Article

Metformin - a Future Therapy for Neurodegenerative Diseases.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2614, doi. 10.1007/s11095-017-2199-y

By:

Markowicz-Piasecka, Magdalena;
Sikora, Joanna;
Szydłowska, Aleksandra;
Skupień, Agata;
Mikiciuk-Olasik, Elżbieta;
Huttunen, Kristiina

Publication type:

Article

Targeted Metabolomics Identifies Pharmacodynamic Biomarkers for BIO 300 Mitigation of Radiation-Induced Lung Injury.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2698, doi. 10.1007/s11095-017-2200-9

By:

Jones, Jace;
Jackson, Isabel;
Vujaskovic, Zeljko;
Kaytor, Michael;
Kane, Maureen

Publication type:

Article

miR-542-3p Appended Sorafenib/All- trans Retinoic Acid (ATRA)-Loaded Lipid Nanoparticles to Enhance the Anticancer Efficacy in Gastric Cancers.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2710, doi. 10.1007/s11095-017-2202-7

By:

Li, Tong;
Zhang, Yu;
Meng, Yuan-Pu;
Bo, Li-Shan;
Ke, Wen-Bo

Publication type:

Article

Good Things in Small Packages: an Innovative Delivery Approach for Inhaled Insulin.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2568, doi. 10.1007/s11095-017-2215-2

By:

Fink, James;
Molloy, Lisa;
Patton, John;
Galindo-Filho, Valdecir;
Melo Barcelar, Jacqueline;
Alcoforado, Luciana;
Brandão, Simone;
Andrade, Armèle

Publication type:

Article

Benchmarking of Human Dose Prediction for Inhaled Medicines from Preclinical In Vivo Data.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2557, doi. 10.1007/s11095-017-2218-z

By:

Ericsson, Therese;
Fridén, Markus;
Kärrman-Mårdh, Carina;
Dainty, Ian;
Grime, Ken

Publication type:

Article

The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2498, doi. 10.1007/s11095-017-2220-5

By:

Price, Daniel;
Luscombe, Chris;
Eddershaw, Peter;
Edwards, Chris;
Gumbleton, Mark

Publication type:

Article

Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2488, doi. 10.1007/s11095-017-2234-z

By:

Gukasyan, Hovhannes;
Uchiyama, Tomomi;
Kim, Kwang-Jin;
Ehrhardt, Carsten;
Wu, Sharon;
Borok, Zea;
Crandall, Edward;
Lee, Vincent

Publication type:

Article

Predicting Pulmonary Pharmacokinetics from In Vitro Properties of Dry Powder Inhalers.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2541, doi. 10.1007/s11095-017-2235-y

By:

Bhagwat, Sharvari;
Schilling, Uta;
Chen, Mong-Jen;
Wei, Xiangyin;
Delvadia, Renishkumar;
Absar, Mohammad;
Saluja, Bhawana;
Hochhaus, Günther

Publication type:

Article

A Multiparticulate Delivery System for Potential Colonic Targeting Using Bovine Serum Albumin as a Model Protein.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2663, doi. 10.1007/s11095-017-2237-9

By:

Jiang, Bowen;
Yu, Hua;
Zhang, Yongrong;
Feng, Hanping;
Hoag, Stephen

Publication type:

Article

Model Informed Pediatric Development Applied to Bilastine: Ontogenic PK Model Development, Dose Selection for First Time in Children and PK Study Design.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2720, doi. 10.1007/s11095-017-2248-6

By:

Vozmediano, Valvanera;
Sologuren, Ander;
Lukas, John;
Leal, Nerea;
Rodriguez, Mónica

Publication type:

Article

Delivery of HSP90 Inhibitor Using Water Soluble Polymeric Conjugates with High Drug Payload.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2735, doi. 10.1007/s11095-017-2249-5

By:

Suárez del Pino, Jose;
Kolhatkar, Rohit

Publication type:

Article

A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2532, doi. 10.1007/s11095-017-2251-y

By:

Bosquillon, Cynthia;
Madlova, Michaela;
Patel, Nilesh;
Clear, Nicola;
Forbes, Ben

Publication type:

Article

A Study of Moisture Sorption and Dielectric Processes of Starch and Sodium Starch Glycolate.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2675, doi. 10.1007/s11095-017-2252-x

By:

Hiew, Tze;
Huang, Rongying;
Popov, Ivan;
Feldman, Yuri;
Heng, Paul

Publication type:

Article

Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2689, doi. 10.1007/s11095-017-2254-8

By:

Arnfast, Lærke;
Kamruzzaman, Md;
Löbmann, Korbinian;
Aho, Johanna;
Baldursdottir, Stefania;
Rades, Thomas;
Rantanen, Jukka

Publication type:

Article

Pharmacokinetic and Tissue Distribution Profile of Long Acting Tenofovir Alafenamide and Elvitegravir Loaded Nanoparticles in Humanized Mice Model.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2749, doi. 10.1007/s11095-017-2255-7

By:

Prathipati, Pavan;
Mandal, Subhra;
Pon, Gregory;
Vivekanandan, Renuga;
Destache, Christopher

Publication type:

Article

Photodegradation Pathways of Protein Disulfides: Human Growth Hormone.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2756, doi. 10.1007/s11095-017-2256-6

By:

Steinmann, Daniel;
Mozziconacci, Olivier;
Bommana, Rupesh;
Stobaugh, John;
Wang, Y.;
Schöneich, Christian

Publication type:

Article

Purification of Drug Loaded PLGA Nanoparticles Prepared by Emulsification Solvent Evaporation Using Stirred Cell Ultrafiltration Technique.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2779, doi. 10.1007/s11095-017-2257-5

By:

Paswan, Suresh;
Saini, T.

Publication type:

Article

In Vitro-In Vivo Relationship of Amorphous Insoluble API (Progesterone) in PLGA Microspheres.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2787, doi. 10.1007/s11095-017-2258-4

By:

Pu, Chenguang;
Wang, Qiao;
Zhang, Hongjuan;
Gou, Jingxin;
Guo, Yuting;
Tan, Xinyi;
Xie, Bin;
Yin, Na;
He, Haibing;
Zhang, Yu;
Wang, Yanjiao;
Yin, Tian;
Tang, Xing

Publication type:

Article

Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2579, doi. 10.1007/s11095-017-2259-3

By:

Malik, Paul;
Phipps, Colin;
Edginton, Andrea;
Blay, Jonathan

Publication type:

Article

Folate Conjugated Hybrid Nanocarrier for Targeted Letrozole Delivery in Breast Cancer Treatment.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2798, doi. 10.1007/s11095-017-2260-x

By:

Hemati Azandaryani, Abbas;
Kashanian, Soheila;
Derakhshandeh, Katayoun

Publication type:

Article

Administration of a Sol-Gel Formulation of Phenylephrine Using Low-Temperature Hollow Microneedle for Treatment of Intermittent Fecal Incontinence.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2809, doi. 10.1007/s11095-017-2261-9

By:

Lee, Hyunji;
Park, Jung-Hwan;
Park, Jung

Publication type:

Article

Chemical and Biophysical Characteristics of Monoclonal Antibody Solutions Containing Aggregates Formed during Metal Catalyzed Oxidation.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2817, doi. 10.1007/s11095-017-2262-8

By:

Narhi, Linda;
Luo, Quanzhou;
Wypych, Jette;
Torosantucci, Riccardo;
Hawe, Andrea;
Fujimori, Kiyoshi;
Nashed-Samuel, Yasser;
Jawa, Vibha;
Joubert, Marisa;
Jiskoot, Wim

Publication type:

Article

Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer's Disease.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2652, doi. 10.1007/s11095-017-2263-7

By:

Vellonen, Kati-Sisko;
Ihalainen, Jouni;
Boucau, Marie-Christine;
Gosselet, Fabien;
Picardat, Théo;
Gynther, Mikko;
Kanninen, Katja;
White, Anthony;
Malm, Tarja;
Koistinaho, Jari;
Forsberg, Markus;
Ruponen, Marika

Publication type:

Article

Co-Delivery of Doxorubicin and Survivin shRNA-Expressing Plasmid Via Microenvironment-Responsive Dendritic Mesoporous Silica Nanoparticles for Synergistic Cancer Therapy.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2829, doi. 10.1007/s11095-017-2264-6

By:

Li, Zhengxiong;
Zhang, Linlin;
Tang, Cui;
Yin, Chunhua

Publication type:

Article

Phase Behavior of Ritonavir Amorphous Solid Dispersions during Hydration and Dissolution.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2842, doi. 10.1007/s11095-017-2265-5

By:

Purohit, Hitesh;
Taylor, Lynne

Publication type:

Article

Biophysical Aspects of Alzheimer's Disease: Implications for Pharmaceutical Sciences.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2628, doi. 10.1007/s11095-017-2266-4

By:

Arosio, Paolo

Publication type:

Article

Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2637, doi. 10.1007/s11095-017-2267-3

By:

Storck, Steffen;
Pietrzik, Claus

Publication type:

Article

Multidose Preservative Free Eyedrops by Selective Removal of Benzalkonium Chloride from Ocular Formulations.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2862, doi. 10.1007/s11095-017-2270-8

By:

Hsu, Kuan-Hui;
Gupta, Karishma;
Nayaka, Harish;
Donthi, Aashrit;
Kaul, Siddarth;
Chauhan, Anuj

Publication type:

Article

A Novel Phenylchromane Derivative Increases the Rate of Glucose Uptake in L6 Myotubes and Augments Insulin Secretion from Pancreatic Beta-Cells by Activating AMPK.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2873, doi. 10.1007/s11095-017-2271-7

By:

Rozentul, Naomi;
Avrahami, Yosef;
Shubely, Moran;
Levy, Laura;
Munder, Anna;
Cohen, Guy;
Cerasi, Erol;
Sasson, Shlomo;
Gruzman, Arie

Publication type:

Article

EphA2 Targeted Doxorubicin-Nanoliposomes for Osteosarcoma Treatment.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2891, doi. 10.1007/s11095-017-2272-6

By:

Haghiralsadat, Fateme;
Amoabediny, Ghasem;
Naderinezhad, Samira;
Nazmi, Kamran;
De Boer, Jantine;
Zandieh-Doulabi, Behrouz;
Forouzanfar, Tymour;
Helder, Marco

Publication type:

Article

Dependence of Friability on Tablet Mechanical Properties and a Predictive Approach for Binary Mixtures.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2901, doi. 10.1007/s11095-017-2273-5

By:

Paul, Shubhajit;
Sun, Changquan

Publication type:

Article

Nanoparticulate Impurities Isolated from Pharmaceutical-Grade Sucrose Are a Potential Threat to Protein Stability.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2910, doi. 10.1007/s11095-017-2274-4

By:

Weinbuch, Daniel;
Ruigrok, Mitchel;
Jiskoot, Wim;
Hawe, Andrea

Publication type:

Article

Microradiopharmaceutical for Metastatic Melanoma.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2922, doi. 10.1007/s11095-017-2275-3

By:

Rosa, Thiago;
Santos, Sofia;
Jesus Andreoli Pinto, Terezina;
Ghisleni, Daniele;
Barja-Fidalgo, Thereza;
Ricci-Junior, Eduardo;
Al-Qahtani, Mohammed;
Kozempel, Jan;
Bernardes, Emerson;
Santos-Oliveira, Ralph

Publication type:

Article

Inhalation Biopharmaceutics: Progress Towards Comprehending the Fate of Inhaled Medicines.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2451, doi. 10.1007/s11095-017-2304-2

By:

Ehrhardt, Carsten

Publication type:

Article

Model-Based Methods in the Biopharmaceutical Process Lifecycle.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2596, doi. 10.1007/s11095-017-2308-y

By:

Kroll, Paul;
Hofer, Alexandra;
Ulonska, Sophia;
Kager, Julian;
Herwig, Christoph

Publication type:

Article

A Biocompatible Synthetic Lung Fluid Based on Human Respiratory Tract Lining Fluid Composition.

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2454, doi. 10.1007/s11095-017-2169-4

By:

Kumar, Abhinav;
Terakosolphan, Wachirun;
Hassoun, Mireille;
Vandera, Kalliopi-Kelli;
Novicky, Astrid;
Harvey, Richard;
Royall, Paul;
Bicer, Elif;
Eriksson, Jonny;
Edwards, Katarina;
Valkenborg, Dirk;
Nelissen, Inge;
Hassall, Dave;
Mudway, Ian;
Forbes, Ben

Publication type:

Article