Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves.

Whaley, A. K.; Ponkratova, A. O.; Orlova, A. A.; Serebryakov, E. B.; Smirnov, S. N.; Proksh, P.; Ionov, N. S.; Poroikov, V. V.; Luzhanin, V. G.

Phytochemical analysis of cloudberry leaves isolated one new (1) and four well-known compounds (2-5) and established their structures. Compounds 1 (4-O-α-L-arabinofuranosylellagic acid) and 2 [(–)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3-O-β-D-glucuronide (3), quercetin 3-O-β-D-2′′-galloylglucuronide (4), and kaempferol 3-O-β-D-glucuronide (5). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1-5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.

METABOLITES; PHYTOCHEMICALS; RUBUS; FLAVONOID glycosides; POLYPHENOLS; SECONDARY analysis; FOLIAR diagnosis

Pharmaceutical Chemistry Journal, 2021, Vol 55, Issue 3, p253

0091-150X

Academic Journal

10.1007/s11094-021-02407-y