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- Title
Synthesis, Toxicity, and Antituberculosis Activity of Isoniazid Derivatives Containing Sterically Hindered Phenols.
- Authors
Oludina, Yu.; Voloshina, A.; Kulik, M.; Zobov, V.; Bukharov, S.; Tagasheva, R.; Nugumanova, G.; Burilov, A.; Kravchenko, M.; Skornyakov, S.; Rusinov, G.
- Abstract
The toxicity and tuberculostatic activity of new isoniazid derivatives containing sterically hindered phenols were investigated. The investigated isoniazid derivatives exhibited lower activity and toxicity than isoniazid.
- Subjects
ANTITUBERCULAR agents; PHARMACEUTICAL chemistry; DRUG activation; ISONIAZID; CHEMICAL derivatives; PHENOLS
- Publication
Pharmaceutical Chemistry Journal, 2014, Vol 48, Issue 1, p5
- ISSN
0091-150X
- Publication type
Academic Journal
- DOI
10.1007/s11094-014-1032-8