Title: Quantitative determination of thiosens in a new liposomal drug form.
Authors: Sanarova, E.; Polozkova, A.; Meerovich, I.; Lantsova, A.; Yartseva, I.; Orlova, O.; Oborotova, N.
Abstract: A procedure for the spectrophotometric quantification of thiosens in a new lyophilized liposomal drug form containing lecithin, cholesterol, and PEG-2000-DSPE at a molar ratio of 1:0.22:0.002 in addition to sucrose solution (cryoprotector) at a lecithin:cryoprotectant mass ratio of 1:2 was developed. The influence of excipients on the analytical results and the observance of the Bouguer-Lambert-Beer law was evaluated.
Subjects: LIPOSOMES; SPECTROPHOTOMETRY; LECITHIN; CHOLESTEROL; POLYETHYLENE glycol; FREEZE-drying; EXCIPIENTS
Publication: Pharmaceutical Chemistry Journal, 2012, Vol 46, Issue 6, p386
ISSN: 0091-150X
Publication type: Academic Journal
DOI: 10.1007/s11094-012-0805-1

Quantitative determination of thiosens in a new liposomal drug form.

Sanarova, E.; Polozkova, A.; Meerovich, I.; Lantsova, A.; Yartseva, I.; Orlova, O.; Oborotova, N.