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- Title
Quantitative determination of thiosens in a new liposomal drug form.
- Authors
Sanarova, E.; Polozkova, A.; Meerovich, I.; Lantsova, A.; Yartseva, I.; Orlova, O.; Oborotova, N.
- Abstract
A procedure for the spectrophotometric quantification of thiosens in a new lyophilized liposomal drug form containing lecithin, cholesterol, and PEG-2000-DSPE at a molar ratio of 1:0.22:0.002 in addition to sucrose solution (cryoprotector) at a lecithin:cryoprotectant mass ratio of 1:2 was developed. The influence of excipients on the analytical results and the observance of the Bouguer-Lambert-Beer law was evaluated.
- Subjects
LIPOSOMES; SPECTROPHOTOMETRY; LECITHIN; CHOLESTEROL; POLYETHYLENE glycol; FREEZE-drying; EXCIPIENTS
- Publication
Pharmaceutical Chemistry Journal, 2012, Vol 46, Issue 6, p386
- ISSN
0091-150X
- Publication type
Academic Journal
- DOI
10.1007/s11094-012-0805-1