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- Title
Synthesis and antibacterial and antifungal properties of some phosphorus-containing 1,2-dihydroxynaphthalenes.
- Authors
Khasiyatullina, N.; Mironov, V.; Bogdanov, A.; Zobov, V.; Voloshina, A.; Kulik, N.; Konovalov, A.
- Abstract
A series of phosphorus-containing 1,2-dihydroxynaphthalenes have been obtained via the reaction of 1,2-naphthoquinone derivatives with tri( n-butyl)- or triphenylphosphine followed by treatment of the intermediate phosphobetaines with various acids. The antimicrobial activity of the synthesized compounds has been studied and the structure—activity relationship established, which gives grounds for the search for new biologically active compounds in this direction.
- Subjects
ANTIFUNGAL agents; PHOSPHORUS; NAPHTHOQUINONE; ANTI-infective agents; ANTIBACTERIAL agents
- Publication
Pharmaceutical Chemistry Journal, 2009, Vol 43, Issue 11, p610
- ISSN
0091-150X
- Publication type
Academic Journal
- DOI
10.1007/s11094-010-0363-3