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- Title
Pharmacokinetics of ximedone.
- Authors
Pogorel'tsev, V. I.; Garmonov, S. Yu.; Evgen'ev, M. I.; Degterev, E. V.; Reznik, V. S.
- Abstract
Optimum conditions for the spectrophotometric determination of pyrimidine derivatives in biological fluids of humans are determined. This method has been used for the investigation of the pharmacokinetics of the new immunomodulant ximedone in humans, dogs, and rats upon administration of the drug in different ways. Interspecific relationships of the key parameters of ximedone pharmacokinetics are established.
- Subjects
PYRIMIDINES; SPECTROPHOTOMETRY; BODY fluids; PHARMACOKINETICS; PHARMACEUTICAL research; PHARMACEUTICAL chemistry
- Publication
Pharmaceutical Chemistry Journal, 2006, Vol 40, Issue 7, p349
- ISSN
0091-150X
- Publication type
Academic Journal
- DOI
10.1007/s11094-006-0125-4