Works matching DE "PYRUVATE dehydrogenase complex"

Results: 260

Pyruvic Acid Production from Sucrose by Escherichia coli Pyruvate Dehydrogenase Variants.

Published in:

Fermentation (Basel), 2023, v. 9, n. 5, p. 478, doi. 10.3390/fermentation9050478

By:

Moxley, W. Chris;
Eiteman, Mark A.

Publication type:

Article

Amino acid ratio combinations as biomarkers for discriminating patients with pyruvate dehydrogenase complex deficiency from other inborn errors of metabolism.

Published in:

Molecular Genetics & Genomic Medicine, 2024, v. 12, n. 1, p. 1, doi. 10.1002/mgg3.2283

By:

Verma, Anisha;
Lehman, April N.;
Gokcan, Hatice;
Cropcho, Lorna;
Black, Danielle;
Dobrowolski, Steven F.;
Vockley, Jerry;
Bedoyan, Jirair K.

Publication type:

Article

Pyruvate dehydrogenase deficiency disease detected by the enzyme activity of peripheral leukocytes.

Published in:

Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 8, p. 1, doi. 10.1002/mgg3.1728

By:

Ma, YanYan;
Zhang, YaoGang;
Zhang, Tao;
Man, Zhu;
Su, XiaoMing;
Hao, ShuJing;
Wang, TianZe

Publication type:

Article

Clinical exome sequencing reveals a mutation in PDHA1 in Leigh syndrome: A case of a Chinese boy with lethal neuropathy.

Published in:

Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 4, p. 1, doi. 10.1002/mgg3.1651

By:

Gong, Ke;
Xie, Li;
Wu, Zhong‐shi;
Xie, Xia;
Zhang, Xing‐xing;
Chen, Jin‐Lan

Publication type:

Article

TCA cycle impairment leads to PIN2 internalization and degradation via reduced MAB4 level and ARA6 components in Arabidopsis roots.

Published in:

Frontiers in Plant Science, 2024, p. 1, doi. 10.3389/fpls.2024.1462235

By:

Song, Xiaomin;
Ohbayashi, Iwai;
Sun, Song;
Wang, Qiuli;
Yang, Yi;
Lu, Mengyuan;
Liu, Yuanyuan;
Sawa, Shinichiro;
Furutani, Masahiko

Publication type:

Article

Singapore Grouper Iridovirus Induces Glucose Metabolism in Infected Cells by Activation of Mammalian Target of Rapamycin Signaling.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.827818

By:

Guo, Xixi;
Zheng, Qi;
Pan, Zanbin;
Huang, Youhua;
Huang, Xiaohong;
Qin, Qiwei

Publication type:

Article

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism.

Published in:

Diabetes & Metabolism Journal, 2018, v. 42, n. 4, p. 270, doi. 10.4093/dmj.2018.0101

By:

Sungmi Park;
Jae-Han Jeon;
Byong-Keol Min;
Chae-Myeong Ha;
Themis Thoudam;
Bo-Yoon Park;
In-Kyu Lee

Publication type:

Article

The changing face of dietary therapy for epilepsy.

Published in:

2016

By:

Pasca, Ludovica;
De Giorgis, Valentina;
Macasaet, Joyce;
Trentani, Claudia;
Tagliabue, Anna;
Veggiotti, Pierangelo;
Macasaet, Joyce Ann

Publication type:

journal article

Elevated plasma citrulline: look for dihydrolipoamide dehydrogenase deficiency.

Published in:

European Journal of Pediatrics, 2014, v. 173, n. 2, p. 243, doi. 10.1007/s00431-013-2153-x

By:

Haviv, Ruby;
Zeharia, Avraham;
Belaiche, Corinne;
Haimi Cohen, Yishai;
Saada, Ann

Publication type:

Article

Calcium acts as a central player in melatonin antitumor activity in sarcoma cells.

Published in:

Cellular Oncology (2211-3428), 2022, v. 45, n. 3, p. 415, doi. 10.1007/s13402-022-00674-9

By:

Sánchez-Sánchez, Ana M.;
Turos-Cabal, María;
Puente-Moncada, Noelia;
Herrera, Federico;
Rodríguez, Carmen;
Martín, Vanesa

Publication type:

Article

Boosted TCA cycle enhances survival of zebrafish to Vibrio alginolyticus infection.

Published in:

Virulence, 2018, v. 9, n. 1, p. 634, doi. 10.1080/21505594.2017.1423188

By:

Yang, Man-Jun;
Cheng, Zhi-Xue;
Jiang, Ming;
Zeng, Zao-Hai;
Peng, Bo;
Peng, Xuan-Xian;
Li, Hui

Publication type:

Article

Epileptic phenotypes in children with early‐onset mitochondrial diseases.

Published in:

Acta Neurologica Scandinavica, 2019, v. 140, n. 3, p. 184, doi. 10.1111/ane.13130

By:

Matricardi, Sara;
Canafoglia, Laura;
Ardissone, Anna;
Moroni, Isabella;
Ragona, Francesca;
Ghezzi, Daniele;
Lamantea, Eleonora;
Nardocci, Nardo;
Franceschetti, Silvana;
Granata, Tiziana

Publication type:

Article

A modified Atkin's diet for an infant with pyruvate dehydrogenase complex deficiency confirmed by PDHA1 gene mutation.

Published in:

2014

By:

Kim, Jeong A.;
Rita Yu;
Wonha Jo;
Youn Hee Ko;
Jin-Sung Lee;
Heung Dong Kim;
Hoon-Chul Kang

Publication type:

Case Study

Case Report of Pyruvate Dehydrogenase Deficiency With Unusual Increase of Fats During Ketogenic Diet Treatment.

Published in:

2012

By:

Pisa, Veronica Di;
Cecconi, Ilaria;
Gentile, Valentina;
Pietro, Elena Di;
Marchiani, Valentina;
Verrotti, Alberto;
Franzoni, Emilio

Publication type:

Case Study

An Updated View on the Molecular Pathomechanisms of Human Dihydrolipoamide Dehydrogenase Deficiency in Light of Novel Crystallographic Evidence.

Published in:

Neurochemical Research, 2019, v. 44, n. 10, p. 2307, doi. 10.1007/s11064-019-02766-9

By:

Ambrus, Attila

Publication type:

Article

Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerative Diseases.

Published in:

Neurochemical Research, 2013, v. 38, n. 8, p. 1523, doi. 10.1007/s11064-013-1060-x

By:

Szutowicz, Andrzej;
Bielarczyk, Hanna;
Jankowska-Kulawy, Agnieszka;
Pawełczyk, Tadeusz;
Ronowska, Anna

Publication type:

Article

Clinical and biochemical characterization of four patients with mutations in ECHS1.

Published in:

Orphanet Journal of Rare Diseases, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13023-015-0290-1

By:

Ferdinandusse, Sacha;
Friederich, Marisa W.;
Burlina, Alberto;
Ruiter, Jos P. N.;
Coughlin II, Curtis R.;
Dishop, Megan K.;
Gallagher, Renata C.;
Bedoyan, Jirair K.;
Vaz, Frédéric M.;
Waterham, Hans R.;
Gowan, Katherine;
Chatfield, Kathryn;
Bloom, Kaitlyn;
Bennett, Michael J.;
Elpeleg, Orly;
Van Hove, Johan L. K.;
Wanders, Ronald J. A.

Publication type:

Article

PDK2 Deficiency Prevents Ovariectomy‐Induced Bone Loss in Mice by Regulating the RANKL‐NFATc1 Pathway During Osteoclastogenesis.

Published in:

Journal of Bone & Mineral Research, 2021, v. 36, n. 3, p. 553, doi. 10.1002/jbmr.4202

By:

Lee, Ji‐Min;
Kim, Min‐Ji;
Lee, Sun Joo;
Kim, Byung‐Gyu;
Choi, Je‐Yong;
Lee, Seung Mi;
Ham, Hye Jin;
Koh, Jung‐Min;
Jeon, Jae‐Han;
Lee, In‐Kyu

Publication type:

Article

The N-terminal 1–55 residues domain of pyruvate dehydrogenase from Escherichia coli assembles as a dimer in solution.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 6, p. 271, doi. 10.1093/protein/gzz044

By:

Wang, Yuanyuan;
Gong, Zemao;
Fang, Han;
Zhi, Dongming;
Tao, Hu

Publication type:

Article

Impaired hippocampal glucose metabolism during and after flurothyl-induced seizures in mice: Reduced phosphorylation coincides with reduced activity of pyruvate dehydrogenase.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 7, p. 1172, doi. 10.1111/epi.13796

By:

McDonald, Tanya S.;
Borges, Karin

Publication type:

Article

Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.

Published in:

Epilepsia (Series 4), 2015, v. 56, n. 8, p. 1185, doi. 10.1111/epi.13057

By:

Wilmshurst, Jo M.;
Gaillard, William D.;
Vinayan, Kollencheri Puthenveettil;
Tsuchida, Tammy N.;
Plouin, Perrine;
Van Bogaert, Patrick;
Carrizosa, Jaime;
Elia, Maurizio;
Craiu, Dana;
Jovic, Nebojsa J.;
Nordli, Doug;
Hirtz, Deborah;
Wong, Virginia;
Glauser, Tracy;
Mizrahi, Eli M.;
Cross, J. Helen

Publication type:

Article

Establishment of markerless gene deletion tools in thermophilic Bacillus smithii and construction of multiple mutant strains.

Published in:

Microbial Cell Factories, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12934-015-0286-5

By:

Bosma, Elleke F.;
van de Weijer, Antonius H. P.;
van der Vlist, Laurens;
de Vos, Willem M.;
van der Oost, John;
van Kranenburg, Richard

Publication type:

Article

Engineering of Serine-Deamination pathway, Entner-Doudoroff pathway and pyruvate dehydrogenase complex to improve poly(3-hydroxybutyrate) production in Escherichia coli.

Published in:

Microbial Cell Factories, 2014, v. 13, n. 1, p. 68, doi. 10.1186/s12934-014-0172-6

By:

Yan Zhang;
Zhenquan Lin;
Qiaojie Liu;
Yifan Li;
Zhiwen Wang;
Hongwu Ma;
Tao Chen;
Xueming Zhao

Publication type:

Article

Glycerol, a possible new player in the biology of trypanosomes.

Published in:

PLoS Pathogens, 2021, v. 17, n. 12, p. 1, doi. 10.1371/journal.ppat.1010035

By:

Bringaud, Frédéric;
Plazolles, Nicolas;
Pineda, Erika;
Asencio, Corinne;
Villafraz, Oriana;
Millerioux, Yoann;
Rivière, Loïc;
Tetaud, Emmanuel

Publication type:

Article

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.

Published in:

PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009734

By:

Steketee, Pieter C.;
Dickie, Emily A.;
Iremonger, James;
Crouch, Kathryn;
Paxton, Edith;
Jayaraman, Siddharth;
Alfituri, Omar A.;
Awuah-Mensah, Georgina;
Ritchie, Ryan;
Schnaufer, Achim;
Rowan, Tim;
de Koning, Harry P.;
Gadelha, Catarina;
Wickstead, Bill;
Barrett, Michael P.;
Morrison, Liam J.

Publication type:

Article

Effects of Tumor Necrosis Factor Inhibitor on Serum Level of HLA-B27 and PDCD-1 in Patients with Ankylosing Spondylitis.

Published in:

Cell Biochemistry & Biophysics, 2014, v. 70, n. 2, p. 1453, doi. 10.1007/s12013-014-0082-6

By:

Chen, Xiaogang;
Zhou, Xiaoqing;
Li, Xia;
Tang, Jinshan;
Hu, Xiaowu;
Wang, Junsheng;
Xu, Cheng

Publication type:

Article

Nuclear Magnetic Resonance Approaches in the Study of 2-Oxo Acid Dehydrogenase Multienzyme Complexes- A Literature Review.

Published in:

Molecules, 2013, v. 18, n. 10, p. 11873, doi. 10.3390/molecules181011873

By:

Kumaran, Sowmini;
Patel, Mulchand S.;
Jordan, Frank

Publication type:

Article

Diabetes - clinical.

Published in:: Nephrology Dialysis Transplantation, 2013, v. 28, n. suppl_1, p. i16, doi. 10.1093/ndt/gft148
Publication type:: Article

PDH Inhibition in Drosophila Ameliorates Sensory Dysfunction Induced by Vincristine Treatment in the Chemotherapy-Induced Peripheral Neuropathy Models.

Published in:

Biomedicines, 2025, v. 13, n. 4, p. 783, doi. 10.3390/biomedicines13040783

By:

Song, Harim;
Kim, Sohee;
Han, Ji Eun;
Kang, Kyong-hwa;
Koh, Hyongjong

Publication type:

Article

A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3171, doi. 10.3390/biomedicines10123171

By:

Vaz, Raquel;
Wincent, Josephine;
Elfissi, Najla;
Rosengren Forsblad, Kristina;
Pettersson, Maria;
Naess, Karin;
Wedell, Anna;
Wredenberg, Anna;
Lindstrand, Anna;
Ygberg, Sofia

Publication type:

Article

Pyruvate Dehydrogenase A1 Phosphorylated by Insulin Associates with Pyruvate Kinase M2 and Induces LINC00273 through Histone Acetylation.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1256, doi. 10.3390/biomedicines10061256

By:

Hossain, Abu Jubayer;
Islam, Rokibul;
Kim, Jae-Gyu;
Dogsom, Oyungerel;
Cap, Kim Cuong;
Park, Jae-Bong

Publication type:

Article

The decrotonylase FoSir5 facilitates mitochondrial metabolic state switching in conidial germination of Fusarium oxysporum.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75583

By:

Ning Zhang;
Limin Song;
Yang Xu;
Xueyuan Pei;
Luisi, Ben F.;
Wenxing Liang

Publication type:

Article

Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth.

Published in:

Cancer & Metabolism, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40170-021-00275-4

By:

Echeverri Ruiz, Nancy P.;
Mohan, Vijay;
Wu, Jinghai;
Scott, Sabina;
Kreamer, McKenzie;
Benej, Martin;
Golias, Tereza;
Papandreou, Ioanna;
Denko, Nicholas C.

Publication type:

Article

Repurposing INCI-registered compounds as skin prebiotics for probiotic Staphylococcus epidermidis against UV-B.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78132-5

By:

Balasubramaniam, Arun;
Adi, Prakoso;
Tra My, Do Thi;
Keshari, Sunita;
Sankar, Raman;
Chen, Chien-Lung;
Huang, Chun-Ming

Publication type:

Article

Pyruvate dehydrogenase complex—enzyme 2, a new target for Listeria spp. detection identified using combined phage display technologies.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72159-4

By:

Moreira, Gustavo Marçal Schmidt Garcia;
Köllner, Sarah Mara Stella;
Helmsing, Saskia;
Jänsch, Lothar;
Meier, Anja;
Gronow, Sabine;
Boedeker, Christian;
Dübel, Stefan;
Mendonça, Marcelo;
Moreira, Ângela Nunes;
Conceição, Fabricio Rochedo;
Hust, Michael

Publication type:

Article

A way to thioacetate esters compatible with non-oxidative prebiotic conditions.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71524-7

By:

Leqraa, Naoual;
Nicolet, Yvain;
Milet, Anne;
Vallée, Yannick

Publication type:

Article

Detection and characterization of low‐level mosaicism among clinically unaffected parents of 'sporadic' epidermolysis bullosa simplex cases.

Published in:

British Journal of Dermatology, 2022, v. 187, n. 3, p. 441, doi. 10.1111/bjd.21059

By:

Chen, Fuying;
Deng, Dan;
Pan, Chaolan;
Yao, Zhirong;
Gu, Yan;
Li, Ming

Publication type:

Article

PDK4 Inhibition Ameliorates Melatonin Therapy by Modulating Cerebral Metabolism and Remyelination in an EAE Demyelinating Mouse Model of Multiple Sclerosis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.862316

By:

Ghareghani, Majid;
Farhadi, Zahra;
Rivest, Serge;
Zibara, Kazem

Publication type:

Article

From Africa to Antarctica: Exploring the Metabolism of Fish Heart Mitochondria Across a Wide Thermal Range.

Published in:

Frontiers in Physiology, 2019, p. 1, doi. 10.3389/fphys.2019.01220

By:

Hunter-Manseau, Florence;
Desrosiers, Véronique;
Le François, Nathalie R.;
Dufresne, France;
Detrich III, H. William;
Nozais, Christian;
Blier, Pierre U.

Publication type:

Article

Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 Cells.

Published in:

Toxins, 2023, v. 15, n. 4, p. 244, doi. 10.3390/toxins15040244

By:

Pillay, Yashodani;
Nagiah, Savania;
Chuturgoon, Anil

Publication type:

Article

Engineering Corynebacterium glutamicum Mutants for 3-Methyl-1-butanol Production.

Published in:

Biochemical Genetics, 2019, v. 57, n. 3, p. 443, doi. 10.1007/s10528-019-09906-4

By:

Zhang, Yu;
Zhang, Xiaohuan;
Xiao, Shiyuan;
Qi, Wei;
Xu, Jingliang;
Yuan, Zhenhong;
Wang, Zhongming

Publication type:

Article

Aminoacidopathies: Prevalence, Etiology, Screening, and Treatment Options.

Published in:

Biochemical Genetics, 2018, v. 56, n. 1/2, p. 7, doi. 10.1007/s10528-017-9825-6

By:

Wasim, Muhammad;
Awan, Fazli Rabbi;
Khan, Haq Nawaz;
Tawab, Abdul;
Iqbal, Mazhar;
Ayesha, Hina

Publication type:

Article

Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria.

Published in:

FASEB Journal, 2010, v. 24, n. 12, p. 5033, doi. 10.1096/fj.10.166934

By:

Acin-Perez, Rebeca;
Hoyos, Beatrice;
Gong, Jianli;
Vinogradov, Valerie;
Fischman, Donald A.;
Leitges, Michael;
Borhan, Babak;
Starkov, Anatoly;
Manfredi, Giovanni;
Hammerling, Ulrich

Publication type:

Article

Low-biomass pyruvate production with engineered Vibrio natriegens is accompanied by parapyruvate formation.

Published in:

Microbial Cell Factories, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12934-025-02693-1

By:

Hädrich, Maurice;
Scheuchenegger, Clarissa;
Vital, Sören-Tobias;
Gunkel, Christoph;
Müller, Susanne;
Hoff, Josef;
Borger, Jennifer;
Glawischnig, Erich;
Thoma, Felix;
Blombach, Bastian

Publication type:

Article

A mutation in the E2 subunit of the mitochondrial pyruvate dehydrogenase complex in Arabidopsis reduces plant organ size and enhances the accumulation of amino acids and intermediate products of the TCA Cycle.

Published in:

Planta: An International Journal of Plant Biology, 2012, v. 236, n. 2, p. 387, doi. 10.1007/s00425-012-1620-3

By:

Yu, Hailan;
Du, Xiaoqiu;
Zhang, Fengxia;
Zhang, Fang;
Hu, Yong;
Liu, Shichang;
Jiang, Xiangning;
Wang, Guodong;
Liu, Dong

Publication type:

Article

Metabolic control analysis of l-lactate synthesis pathway in Rhizopus oryzae As 3.2686.

Published in:

Bioprocess & Biosystems Engineering, 2015, v. 38, n. 11, p. 2189, doi. 10.1007/s00449-015-1458-8

By:

Ke, Wei;
Chang, Shu;
Chen, Xiaoju;
Luo, Shuizhong;
Jiang, Shaotong;
Yang, Peizhou;
Wu, Xuefeng;
Zheng, Zhi

Publication type:

Article

Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 10, p. 4397, doi. 10.1007/s00253-015-6387-6

By:

Fu, Yanfen;
Yoon, Jong;
Jarboe, Laura;
Shanks, Jacqueline

Publication type:

Article

Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 16, p. 7003, doi. 10.1007/s00253-014-5745-0

By:

Guo, Hongwei;
Madzak, Catherine;
Du, Guocheng;
Zhou, Jingwen;
Chen, Jian

Publication type:

Article

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

Published in:

Nature, 2013, v. 498, n. 7452, p. 109, doi. 10.1038/nature12154

By:

Kaplon, Joanna;
Zheng, Liang;
Meissl, Katrin;
Chaneton, Barbara;
Selivanov, Vitaly A.;
Mackay, Gillian;
van der Burg, Sjoerd H.;
Verdegaal, Elizabeth M. E.;
Cascante, Marta;
Shlomi, Tomer;
Gottlieb, Eyal;
Peeper, Daniel S.

Publication type:

Article

Role of population heterogeneity and pH factor in natural phenomenon of α-acetolactate overproduction in Lactococcus lactis ssp. lactis bv. diacetylactis B2103/74 diacetyl producer.

Published in:

Applied Biochemistry & Microbiology, 2016, v. 52, n. 8, p. 750, doi. 10.1134/S0003683816080056

By:

Kotova, L.;
Serebrennikov, V.;
Glazunov, A.

Publication type:

Article