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- Title
Novel single nucleotide polymorphism identification in interleukin-6 gene of Pakistani sheep.
- Authors
Ali, Safdar; Babar, Masroor Ellahi; Farid, A. Hossain; Akhtar, Pervez; Awan, Ali Raza
- Abstract
The present study aimed to identify single-nucleotide polymorphism (SNP) in coding and non-coding regions of interleukin-6 (IL-6) gene of Pakistani sheep. The IL-6 gene of 205 animals from nine sheep breeds were sequenced for screening of SNP. Characterizing the IL-6 gene revealed thirteen SNP sites within the intronic region of IL-6 gene. The novel SNPs found in the present study can serve as genetic marker for association studies with susceptibility/resistance to parasite infection in sheep. This is first report of SNP polymorphism of IL-6 gene of Pakistani sheep.
- Subjects
NUCLEOTIDES; GENETIC polymorphisms; INTERLEUKIN-6; SHEEP breeds; BABESIOSIS; SHEEP
- Publication
Molecular Biology Reports, 2011, Vol 38, Issue 3, p2151
- ISSN
0301-4851
- Publication type
Academic Journal
- DOI
10.1007/s11033-010-0342-5