Works matching DE "SIRTUINS"

Results: 2672

SIRT1: potential target in glucocorticoid-resistant diseases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1514745

By:

Xie, Jun;
Che, Siyi;
Liu, Jiao;
Long, Xiaoru

Publication type:

Article

The role of sirtuins in the regulation of reactive oxygen species in myocardial ischemia/reperfusion injury.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 6, p. 3501, doi. 10.1007/s11010-024-05204-9

By:

Wang, Zheng;
Zhao, Xiaopeng;
Lu, Mingjing;
Wang, Naiyu;
Xu, Shu;
Min, Dongyu;
Wang, Lijie

Publication type:

Article

β-Nicotinamide Mononucleotide Alleviates Sepsis-associated Acute Kidney Injury by Activating NAD+/SIRT3 Signaling.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2089, doi. 10.1007/s12013-024-01619-9

By:

Sun, Chengcheng;
Xiong, Hui;
Guo, Tao

Publication type:

Article

Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.

Published in:

Journal of Bone & Mineral Metabolism, 2025, v. 43, n. 3, p. 203, doi. 10.1007/s00774-024-01574-8

By:

Xiong, Xiaolong;
Huang, Hui;
Wang, Ning;
Zhou, Kai;
Song, Xinghui

Publication type:

Article

miR‐338‐3p Targets SIRT6 to Inhibit Liver Cancer Malignancy and Paclitaxel Resistance.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70089

By:

Huang, Yiyuan;
Huang, Sunhui;
Li, Quan;
Zhang, Hongchang;
Xiao, Wei;
Chen, Yunhui

Publication type:

Article

Hepatocellular carcinoma cells downregulate PGAM2 via SIRT2-mediated deacetylation modification to enhance aerobic glycolysis.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00930-9

By:

Wang, Zexuan;
Guo, Yaoyu;
Hu, Kefei;
He, Tingjiang;
Qin, Tong;
Zhang, Ludan;
Xu, Fang;
Xu, Yuanzhi;
Cheng, Mingjiao;
Zhang, Jintao;
Zhao, Qianwei

Publication type:

Article

SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97019

By:

Karim, Rezwana;
Teng, Wendi;
Behram, Cameron D.;
Lin, Hening

Publication type:

Article

Salvianolic Acid A Attenuates Lipopolysaccharide‐Induced Acute Lung Injury by Activating AMPK/SIRT1/Nrf2 Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 5, p. 1, doi. 10.1002/jbt.70282

By:

Wang, Pengwei;
Sun, Yu;
Zhang, Ru;
Guo, Yongli;
Zhang, Yongheng;
Guo, Shengjie;
Wang, Yemin;
Gao, Jianlian;
Yang, Pengfei;
Deng, Zhijian

Publication type:

Article

Mealworm hydrolysate ameliorates dexamethasone-induced muscle atrophy via sirtuin 1-mediated signaling and Akt pathway.

Published in:

NPJ Science of Food, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41538-025-00432-9

By:

Kim, Sung-Min;
Kim, Jong-Yeon;
Jun, Eun-Min;
Jaiswal, Varun;
Park, Eun-Jung;
Lee, Hae-Jeung

Publication type:

Article

Bergenin Alleviates Myocardial Ischemia/Reperfusion Injury via Regulating SIRT1 Through Ferroptosis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5519, doi. 10.2147/JIR.S497618

By:

Jia, Lingmei;
Yang, Siqi;
Yin, Jun;
Feng, Ouhua;
Wang, Zhigang;
Jia, Min

Publication type:

Article

Adult Neurogenesis Is Regulated by the Endocannabinoid and Kisspeptin Systems.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 3977, doi. 10.3390/ijms26093977

By:

Marino, Marianna;
Di Pietro, Paola;
D'Auria, Raffaella;
Lombardi, Martina;
Pastorino, Grazia Maria Giovanna;
Troisi, Jacopo;
Operto, Francesca Felicia;
Carrizzo, Albino;
Vecchione, Carmine;
Viggiano, Andrea;
Meccariello, Rosaria;
Santoro, Antonietta

Publication type:

Article

PDRN prevents SIRT1 degradation by attenuating autophagy during skin aging.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0321005

By:

Chen, Jingjing;
Qiu, Fanshan;
Shi, Jianfeng;
Huang, Wei;
Zhao, Chenyu;
Han, Qianqian

Publication type:

Article

Sequentially assembled co-delivery nanoplatform of SIRT1 protein and SOX9-expressing plasmid for multipronged therapy of intervertebral disc degeneration.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03401-2

By:

Zhang, Xiaoyu;
Guo, Qianping;
Fang, Jiawei;
Cheng, Qi;
Zhu, Zhuang;
Yu, Qifan;
Wang, Huan;
Hong, Youzhi;
Liu, Chengyuan;
Yang, Huilin;
Zhu, Caihong;
Li, Bin;
Ni, Li

Publication type:

Article

白藜芦醇对颞下颌关节骨关节炎的治疗作用及其机制.

Published in:

Journal of Jilin University (Medicine Edition), 2024, v. 50, n. 6, p. 1547, doi. 10.13481/j.1671⁃587X.20240608

By:

孙高;
何静;
赵琪;
石剑虹;
廖智羚;
田原野;
吴国民

Publication type:

Article

IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100406

By:

Mengjia Li;
Hengchao Zhang;
Xiuyun Wu;
Mengqi Yu;
Qianqian Yang;
Lei Sun;
Wei Li;
Zhongxing Jiang;
Fumin Xue;
Ting Wang;
Xuili An;
Lixiang Chen

Publication type:

Article

Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00422-3

By:

Ramteke, Pranay;
Watson, Bahiyah;
Toci, Mallory;
Tran, Victoria A.;
Johnston, Shira;
Tsingas, Maria;
Barve, Ruteja A.;
Mitra, Ramkrishna;
Loeser, Richard F.;
Collins, John A.;
Risbud, Makarand V.

Publication type:

Article

The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 151, doi. 10.2147/ITT.S500499

By:

Ren, Xiang;
Wang, Zhixian;
Wang, Jing;
Li, Xing;
Wei, Huizhi;
Liu, Chang;
Liu, Shiliang;
Zhu, Yunpeng;
Feng, Chunxiang;
Yin, Yisheng;
Tian, Yiqun;
Wu, Minglong;
Zeng, Xiaoyong

Publication type:

Article

Retraction: Involvement of FOXO Transcription Factors, TRAIL-FasL/Fas, and Sirtuin Proteins Family in Canine Coronavirus Type II-Induced Apoptosis.

Published in:: 2025
Publication type:: Correction Notice

SIRT2 inhibition enhances mitochondrial apoptosis in Brucella-infected bovine placental trophoblast cells.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01518-8

By:

Zhang, Mengyu;
Qi, Lin;
Li, Junmei;
Yuan, NingQiu;
Zhai, Yunyi;
Hao, Mingyue;
Zhou, Dong;
Liu, Wei;
Jin, Yaping;
Wang, Aihua

Publication type:

Article

The Sirt1 Gene Promotes Insulin Secretion in Accord with Diet.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. 1, doi. 10.1371/journal.pbio.0040044

By:

Chanut, Françoise

Publication type:

Article

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells.

Published in:

PLoS Biology, 2005, v. 3, n. 12, p. 1, doi. 10.1371/journal.pbio.0040031

By:

Bordone, Laura;
Motta, Maria Carla;
Picard, Frederic;
Robinson, Ashley;
Jhala, Ulupi S;
Apfeld, Javier;
McDonagh, Thomas;
Lemieux, Madeleine;
McBurney, Michael;
Szilvasi, Akos;
Easlon, Erin J;
Lin, Su-Ju;
Guarente, Leonard

Publication type:

Article

Resveratrol promotes bone mass in ovariectomized rats and the SIRT1 rs7896005 SNP is associated with bone mass in women during perimenopause and early postmenopause.

Published in:

Climacteric, 2023, v. 26, n. 1, p. 25, doi. 10.1080/13697137.2022.2073809

By:

Wang, X.;
Lu, C.;
Chen, Y.;
Wang, Q.;
Bao, X.;
Zhang, Z.;
Huang, X.

Publication type:

Article

Quantitative structure–activity relationship modeling reveals the minimal sequence requirement and amino acid preference of sirtuin-1's deacetylation substrates in diabetes mellitus.

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 3, p. 1, doi. 10.1142/S0219720022500081

By:

Shao, X.;
Kong, W.;
Li, Y.;
Zhang, S.

Publication type:

Article

Studying the Cytotoxic Activity of Newly Designed and Synthesized HDAC Inhibitors Derivatives of Pentanoyl Anilide‐5‐Biguanide.

Published in:

Macromolecular Symposia, 2022, v. 401, n. 1, p. 1, doi. 10.1002/masy.202100346

By:

Sagheer, Othman Makki;
Mohammed, Mohammed Hassan;
Wadi, Jaafar S.;
Ibraheem, Zaid O.

Publication type:

Article

Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway.

Published in:

Biotechnology Letters, 2018, v. 40, n. 3, p. 509, doi. 10.1007/s10529-017-2493-0

By:

Lee, Hyunjin;
Kim, Minji;
Park, Yun-Hee;
Park, Jun-Beom

Publication type:

Article

Overexpression of Sirtuin2 prevents high glucose-induced vascular endothelial cell injury by regulating the p53 and NF-κB signaling pathways.

Published in:

Biotechnology Letters, 2018, v. 40, n. 2, p. 271, doi. 10.1007/s10529-017-2487-y

By:

Zhang, Wenguang;
Liu, Dongmei;
Ren, Jianzhuang;
Zhou, Pengli;
Han, Xinwei

Publication type:

Article

No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2011, v. 26, n. 7, p. 445, doi. 10.1002/hup.1223

By:

Kishi, Taro;
Fukuo, Yasuhisa;
Okochi, Tomo;
Kitajima, Tsuyoshi;
Ujike, Hiroshi;
Inada, Toshiya;
Yamada, Mitsuhiko;
Uchimura, Naohisa;
Sora, Ichiro;
Iyo, Masaomi;
Ozaki, Norio;
Correll, Christoph U.;
Iwata, Nakao

Publication type:

Article

Tissue-specific gene expression and fasting regulation of sirtuin family in gilthead sea bream ( Sparus aurata).

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2017, v. 187, n. 1, p. 153, doi. 10.1007/s00360-016-1014-0

By:

Simó-Mirabet, Paula;
Bermejo-Nogales, Azucena;
Calduch-Giner, Josep;
Pérez-Sánchez, Jaume

Publication type:

Article

Rs12778366 single nucleotide polymorphism of Sirtuin 1 (SIRT1) and response to resveratrol supplementation in patients with type 2 diabetes mellitus.

Published in:

Acta Diabetologica, 2019, v. 56, n. 8, p. 963, doi. 10.1007/s00592-019-01341-6

By:

Gambino, Roberto;
Fanni, Giovanni;
Togliatto, Gabriele;
Ponzo, Valentina;
Goitre, Ilaria;
Cassader, Maurizio;
Brizzi, Maria Felice;
Bo, Simona

Publication type:

Article

SIRT3 Promotes the Development of Esophageal Squamous Cell Carcinoma by Regulating Hexokinase 2 through the AKT Signaling Pathway.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 174, n. 1, p. 81, doi. 10.1007/s10517-022-05653-6

By:

Yuan, M. L.;
Ren, L. H.;
Yu, X. C.;
Dong, J. W.;
Shi, R. H.

Publication type:

Article

Features Neurohumoral and Immune Profile in Children with Functional Disorders of the Autonomic Nervous System Associated with Sirtuin Gene SIRT1 (rs7069102) Polymorphism.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 172, n. 5, p. 583, doi. 10.1007/s10517-022-05439-w

By:

Dolgikh, О. V.;
Zaitseva, N. V.;
Nikonoshina, N. A.

Publication type:

Article

Knockdown of Sirt1 Gene in Mice Results in Lipid Accumulation in the Liver Mediated via PGC-1α-Induced Mitochondrial Dysfunction and Oxidative Stress.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 172, n. 2, p. 180, doi. 10.1007/s10517-021-05359-1

By:

Yang, H.;
Liu, Y.;
Wang, Y.;
Xu, S.;
Su, D.

Publication type:

Article

Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva.

Published in:

Bulletin of Experimental Biology & Medicine, 2020, v. 169, n. 6, p. 821, doi. 10.1007/s10517-020-04986-4

By:

Pukhalskaia, A. E.;
Dyatlova, A. S.;
Linkova, N. S.;
Kozlov, K. L.;
Kvetnaia, T. V.;
Koroleva, M. V.;
Kvetnoy, I. M.

Publication type:

Article

The Role of Urokinase, Tumor Necrosis Factor, and Matrix Metalloproteinase-9 in Monocyte Activation.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 492, doi. 10.1007/s10517-019-04557-2

By:

Menshikov, M. Yu.;
Stafeev, I. S.;
Zubkova, E. S.;
Beloglazova, I. B.;
Ratner, E. I.;
Dergilev, K. V.;
Parfyonova, E. V.

Publication type:

Article

Modulation of the Inflammatory Status of Macrophages and Their Paracrine Effect on the Sensitivity of Adipocytes to Insulin with Sirtuin and PPARγ Receptor Activators.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 165, n. 4, p. 429, doi. 10.1007/s10517-018-4186-7

By:

Stafeev, Yu. S.;
Michurina, S. S.;
Zubkova, E. S.;
Beloglazova, I. B.;
Ratner, E. I.;
Parfenova, E. V.;
Men’shikov, M. Yu.

Publication type:

Article

Expression of Signal Molecules in Culture of Human Endothelial Cells in Atherosclerosis and Restenosis.

Published in:

Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 4, p. 566, doi. 10.1007/s10517-017-3850-7

By:

Kozlov, K.;
Bolotov, I.;
Lin'kova, N.;
Drobintseva, A.

Publication type:

Article

Ganoderma lucidum polysaccharides protect against sepsis-induced cardiac dysfunction by activating SIRT1.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 1, p. 124, doi. 10.1093/jpp/rgab142

By:

Xu, Zhong-Heng;
Su, Xiao;
Yang, Geng;
Qin, Tao;
Liu, Yu

Publication type:

Article

Pioglitazone Protects Against Acetic Acid–Induced Ulcerative Colitis in Rats via Modulation of Sirt1 / Nox4 Signaling and Suppression of Macrophage M1 Polarization.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 6, p. 2429, doi. 10.21608/ZUMJ.2024.298041.3447

By:

Kabil, Soad L.;
Abdelrahman, Abeer A.

Publication type:

Article

RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00451-4

By:

Liu, Hanye;
Yan, Guanghai;
Li, Li;
Wang, Dandan;
Wang, Yu;
Jin, Shan;
Jin, Zhehu;
Li, Liangchang;
Zhu, Lianhua

Publication type:

Article

Neurodegenerative disease: Preventing 'SIRTain' death by mutant huntingtin.

Published in:

2012

By:

Flight, Monica Hoyos

Publication type:

journal article

Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways.

Published in:

GeroScience, 2024, v. 46, n. 5, p. 4729, doi. 10.1007/s11357-024-01209-w

By:

Daneshgar, Nastaran;
Lan, Renny;
Regnier, Michael;
Mackintosh, Samuel G.;
Venkatasubramanian, Ravinandan;
Dai, Dao-Fu

Publication type:

Article

Cellular metabolic pathways of aging in dogs: could p53 and SIRT1 be at play?

Published in:

GeroScience, 2024, v. 46, n. 2, p. 1895, doi. 10.1007/s11357-023-00942-y

By:

Jiménez, Ana Gabriela;
Paul, Kailey D.;
Benson, Mitchel;
Lalwani, Sahil;
Cipolli, William

Publication type:

Article

SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence.

Published in:

GeroScience, 2024, v. 46, n. 1, p. 1107, doi. 10.1007/s11357-023-00863-w

By:

Yu, An;
Yu, Ruofan;
Liu, Haiying;
Ge, Chenliang;
Dang, Weiwei

Publication type:

Article

Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity.

Published in:

GeroScience, 2022, v. 44, n. 3, p. 1505, doi. 10.1007/s11357-022-00559-7

By:

Wang, Zhizhen;
Zheng, Peng;
Chen, Xi;
Xie, Yuanyi;
Weston-Green, Katrina;
Solowij, Nadia;
Chew, Yee Lian;
Huang, Xu-Feng

Publication type:

Article

Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock.

Published in:

GeroScience, 2021, v. 43, n. 3, p. 1217, doi. 10.1007/s11357-020-00311-z

By:

Sims, Carrie A.;
Labiner, Hanna E.;
Shah, Sohini S.;
Baur, Joseph A.

Publication type:

Article

Aging alters acetylation status in skeletal and cardiac muscles.

Published in:

GeroScience, 2020, v. 42, n. 3, p. 963, doi. 10.1007/s11357-020-00171-7

By:

Yeo, Dongwook;
Kang, Chounghun;
Ji, Li Li

Publication type:

Article

Tanshinone IIA inhibits the apoptosis process of nerve cells by upshifting SIRT1 and FOXO3α protein and regulating anti- oxidative stress molecules and inflammatory factors in cerebral infarction model.

Published in:

Immunopharmacology & Immunotoxicology, 2025, v. 47, n. 1, p. 23, doi. 10.1080/08923973.2024.2428662

By:

Xu, Jiao;
Liu, Xiufeng;
Yu, Heng;
Wang, Zhenyu

Publication type:

Article

Sirt1/Nrf2/TNFα; TLR4/Myd88/NF-κB signaling pathways are involved in mediating hepatoprotective effect of bupropion in rat model of myocardial infarction.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 6, p. 872, doi. 10.1080/08923973.2024.2415461

By:

Abdelzaher, Walaa Yehia;
Geddawy, Ayman;
Attya, Mina Ezzat;
Ali, Abdel Hamid Sayed AboBakr;
Elroby Ali, Doaa Mohamed;
Waggas, Dania S.;
Alshaeri, Heba K.;
Ibrahim, Yasmine F.

Publication type:

Article

Sirtinol, a SIRT1 inhibitor, inhibits the EMT and metastasis of 4T1 breast cancer cells and impacts the tumor microenvironment.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 6, p. 829, doi. 10.1080/08923973.2024.2412110

By:

Satam, Sharvari;
Palekar, Nitya;
Premkumar, Kavitha;
Shankar, Bhavani S.

Publication type:

Article

Sirtuins: exploring next-gen therapeutics in the pathogenesis osteoporosis and associated diseases.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 3, p. 277, doi. 10.1080/08923973.2024.2315418

By:

Waykar, Tejal R.;
Mandlik, Satish K.;
Mandlik, Deepa S.

Publication type:

Article