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Title

Measurements of natural levels of<Superscript>14</Superscript>C in human's and rat's tissues by accelerator mass spectrometry in Korea.

Authors

Cho, S.Y.; Lee, J.Y.; Khu, H.J.; Kang, J.H.; Yoon, M.Y.; Kim, J.C.

Abstract

Germanium-68 (270.8 d, EC 100%) is the parent nuclide of&lt;Superscript&gt;68&lt;/Superscript&gt;Ga, aβ+ emitter important to positron emission tomography (PET).&lt;Superscript&gt;68&lt;/Superscript&gt;Ge is obtained by a (p,x) induced nuclear reaction on natural Ga. A typical Ga target assembly consists of liquid Ga contained in a Nb capsule, since Nb is one of the few metals resistant to liquid Ga. Zirconium-88 (83.4 d, via&lt;Superscript&gt;93&lt;/Superscript&gt;Nb(p,α2n)) is one longer-lived radioisotope generated by the proton irradiation of naturally mono-isotopic&lt;Superscript&gt;93&lt;/Superscript&gt;Nb. It decays into&lt;Superscript&gt;88&lt;/Superscript&gt;Y, which, in turn, has been considered a useful radiolabel surrogate for&lt;Superscript&gt;90&lt;/Superscript&gt;Y in the investigation of radiolabeled compounds for cancer radioimmunotherapy. This paper introduces a wet chemical procedure for the processing of Nb/Ga target capsules and the simultaneous recovery of&lt;Superscript&gt;68&lt;/Superscript&gt;Ge and&lt;Superscript&gt;88&lt;/Superscript&gt;Zr.

Subjects

KOREA; PLASMA desorption mass spectrometry; IONIZATION (Atomic physics); ION accelerators; TRACE elements; URANIUM

Publication

Journal of Radioanalytical & Nuclear Chemistry, 2005, Vol 263, Issue 2, p493

ISSN

0236-5731

Publication type

Academic Journal

DOI

10.1007/s10967-005-0081-6

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