Modelling synergistic action of laccase-based biosensor utilizing simultaneous substrates conversion.

Gaidamauskaitė, Evelina; Baronas, Romas; Kulys, Juozas

The response of a laccase-based amperometric biosensor that acts in a synergistic manner was modelled digitally. A mathematical model of the biosensor is based on a system of non-linear reaction diffusion equations. The modelling biosensor comprises three compartments, an enzyme layer, a dialysis membrane and an outer diffusion layer. By changing input parameters the biosensor action was analysed with a special emphasis to the influence of the species concentrations on the synergy of the simultaneous substrates conversion. The digital simulation was carried out using the finite difference technique.

BIOSENSORS; LACCASE; SYNERGETICS; MATHEMATICAL models; ENZYMES; DIALYSIS (Chemistry); BURGERS' equation; DIGITAL computer simulation

Journal of Mathematical Chemistry, 2011, Vol 49, Issue 8, p1573

0259-9791

Academic Journal

10.1007/s10910-011-9844-1