Works matching AU Bujotzek, Alexander

Results: 25

EFFICIENT SIMULATION OF LIGAND–RECEPTOR BINDING PROCESSES USING THE CONFORMATION DYNAMICS APPROACH.

Published in:

Journal of Bioinformatics & Computational Biology, 2009, v. 7, n. 5, p. 811, doi. 10.1142/S0219720009004369

By:

BUJOTZEK, ALEXANDER;
WEBER, MARCUS

Publication type:

Article

DNA-gesteuerte bivalente Präsentation von Liganden für den Östrogenrezeptor.

Published in:

Angewandte Chemie, 2011, v. 123, n. 37, p. 8751, doi. 10.1002/ange.201101655

By:

Abendroth, Frank;
Bujotzek, Alexander;
Shan, Min;
Haag, Rainer;
Weber, Marcus;
Seitz, Oliver

Publication type:

Article

Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 289, doi. 10.1093/protein/gzy021

By:

Regula, Joerg Thomas;
Imhof-Jung, Sabine;
Mølhøj, Michael;
Benz, Joerg;
Ehler, Andreas;
Bujotzek, Alexander;
Schaefer, Wolfgang;
Klein, Christian

Publication type:

Article

Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding.

Published in:

ChemBioChem, 2011, v. 12, n. 17, p. 2587, doi. 10.1002/cbic.201100529

By:

Shan, Min;
Bujotzek, Alexander;
Abendroth, Frank;
Wellner, Anja;
Gust, Ronald;
Seitz, Oliver;
Weber, Marcus;
Haag, Rainer

Publication type:

Article

Structural mechanism of Fab domain dissociation as a measure of interface stability.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 4, p. 201, doi. 10.1007/s10822-023-00501-9

By:

Pomarici, Nancy D.;
Waibl, Franz;
Quoika, Patrick K.;
Bujotzek, Alexander;
Georges, Guy;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04927-7

By:

Abanades, Brennan;
Wong, Wing Ki;
Boyles, Fergus;
Georges, Guy;
Bujotzek, Alexander;
Deane, Charlotte M.

Publication type:

Article

Computational entropy estimation of linear polyether-modified surfaces and correlation with protein resistant properties of such surfaces.

Published in:

Molecular Simulation, 2011, v. 37, n. 11, p. 899, doi. 10.1080/08927022.2011.566606

By:

Weber, Marcus;
Bujotzek, Alexander;
Andrae, Karsten;
Weinhart, Marie;
Haag, Rainer

Publication type:

Article

Back-to-Germline (B2G) Procedure for Antibody Devolution.

Published in:

Antibodies (2073-4468), 2019, v. 8, n. 3, p. 45, doi. 10.3390/antib8030045

By:

Schrade, Anja;
Bujotzek, Alexander;
Spick, Christian;
Wagner, Martina;
Goerl, Johannes;
Wezler, Xenia;
Georges, Guy;
Kontermann, Roland E.;
Brinkmann, Ulrich

Publication type:

Article

Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope.

Published in:

2021

By:

Wong, Wing Ki;
Robinson, Sarah A.;
Bujotzek, Alexander;
Georges, Guy;
Lewis, Alan P.;
Shi, Jiye;
Snowden, James;
Taddese, Bruck;
Deane, Charlotte M.

Publication type:

Report

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins.

Published in:

2020

By:

Jost, Christian;
Darowski, Diana;
Challier, John;
Pulko, Vesna;
Hanisch, Lydia J;
Xu, Wei;
Mössner, Ekkehard;
Bujotzek, Alexander;
Klostermann, Stefan;
Umana, Pablo;
Kontermann, Roland E.;
Klein, Christian

Publication type:

Report

VH-VL orientation prediction for antibody humanization candidate selection: A case study.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 288, doi. 10.1080/19420862.2015.1117720

By:

Bujotzek, Alexander;
Lipsmeier, Florian;
Harris, Seth F;
Benz, Jörg;
Kuglstatter, Andreas;
Georges, Guy

Publication type:

Article

MoFvAb: Modeling the Fv region of antibodies.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 5, p. 838, doi. 10.1080/19420862.2015.1068492

By:

Bujotzek, Alexander;
Fuchs, Angelika;
Qu, Changtao;
Benz, Jörg;
Klostermann, Stefan;
Antes, Iris;
Georges, Guy

Publication type:

Article

DNA-Controlled Bivalent Presentation of Ligands for the Estrogen Receptor.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 37, p. 8592, doi. 10.1002/anie.201101655

By:

Abendroth, Frank;
Bujotzek, Alexander;
Shan, Min;
Haag, Rainer;
Weber, Marcus;
Seitz, Oliver

Publication type:

Article

ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation.

Published in:

Bioinformatics, 2022, v. 38, n. 7, p. 1877, doi. 10.1093/bioinformatics/btac016

By:

Abanades, Brennan;
Georges, Guy;
Bujotzek, Alexander;
Deane, Charlotte M

Publication type:

Article

Thera-SAbDab: the Therapeutic Structural Antibody Database.

Published in:

Nucleic Acids Research, 2020, v. 48, n. D1, p. D383, doi. 10.1093/nar/gkz827

By:

Raybould, Matthew I J;
Marks, Claire;
Lewis, Alan P;
Shi, Jiye;
Bujotzek, Alexander;
Taddese, Bruck;
Deane, Charlotte M

Publication type:

Article

Towards a rational spacer design for bivalent inhibition of estrogen receptor.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 3, p. 253, doi. 10.1007/s10822-011-9417-1

By:

Bujotzek, Alexander;
Min Shan;
Haag, Rainer;
Weber, Marcus

Publication type:

Article

Antibodies exhibit multiple paratope states influencing VH–VL domain orientations.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01319-z

By:

Fernández-Quintero, Monica L.;
Pomarici, Nancy D.;
Math, Barbara A.;
Kroell, Katharina B.;
Waibl, Franz;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R.

Publication type:

Article

ZIBgridfree: efficient conformational analysis by partition-of-unity coupling.

Published in:

Journal of Mathematical Chemistry, 2014, v. 52, n. 3, p. 781, doi. 10.1007/s10910-013-0265-1

By:

Bujotzek, Alexander;
Schütt, Ole;
Nielsen, Adam;
Fackeldey, Konstantin;
Weber, Marcus

Publication type:

Article

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19400-w

By:

Cho, Steven X.;
Rudloff, Ina;
Lao, Jason C.;
Pang, Merrin A.;
Goldberg, Rimma;
Bui, Christine B.;
McLean, Catriona A.;
Stock, Magdalena;
Klassert, Tilman E.;
Slevogt, Hortense;
Mangan, Niamh E.;
Cheng, Wei;
Fischer, Doris;
Gfroerer, Stefan;
Sandhu, Manjeet K.;
Ngo, Devi;
Bujotzek, Alexander;
Lariviere, Laurent;
Schumacher, Felix;
Tiefenthaler, Georg

Publication type:

Article

VH‐VL interdomain dynamics observed by computer simulations and NMR.

Published in:

Proteins, 2020, v. 88, n. 7, p. 830, doi. 10.1002/prot.25872

By:

Fernández‐Quintero, Monica L.;
Hoerschinger, Valentin J.;
Lamp, Leonida M.;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R.

Publication type:

Article

Prediction of VH-VL domain orientation for antibody variable domain modeling.

Published in:

Proteins, 2015, v. 83, n. 4, p. 681, doi. 10.1002/prot.24756

By:

Bujotzek, Alexander;
Dunbar, James;
Lipsmeier, Florian;
Schäfer, Wolfgang;
Antes, Iris;
Deane, Charlotte M.;
Georges, Guy

Publication type:

Article

The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures.

Published in:

Nucleic Acids Research, 2024, v. 52, n. D1, p. D545, doi. 10.1093/nar/gkad1056

By:

Abanades, Brennan;
Olsen, Tobias H;
Raybould, Matthew I J;
Aguilar-Sanjuan, Broncio;
Wong, Wing Ki;
Georges, Guy;
Bujotzek, Alexander;
Deane, Charlotte M

Publication type:

Article

Bispecific antibodies—effects of point mutations on CH3-CH3 interface stability.

Published in:

PEDS: Protein Engineering, Design & Selection, 2022, v. 35, p. 1, doi. 10.1093/protein/gzac012

By:

Pomarici, Nancy D;
Fernández-Quintero, Monica L;
Quoika, Patrick K;
Waibl, Franz;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R

Publication type:

Article

Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.675655

By:

Fernández-Quintero, Monica L.;
Kroell, Katharina B.;
Bacher, Lisa M.;
Loeffler, Johannes R.;
Quoika, Patrick K.;
Georges, Guy;
Bujotzek, Alexander;
Kettenberger, Hubert;
Liedl, Klaus R.

Publication type:

Article

Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.

Published in:

FASEB Journal, 2015, v. 29, n. 5, p. 1763, doi. 10.1096/fj.14-263665

By:

Dengl, Stefan;
Hoffmann, Eike;
Grote, Michael;
Wagner, Cornelia;
Mundigl, Olaf;
Georges, Guy;
Thorey, Irmgard;
Stubenrauch, Kay-Gunnar;
Bujotzek, Alexander;
Josel, Hans-Peter;
Dziadek, Sebastian;
Benz, Joerg;
Brinkmann, Ulrich

Publication type:

Article

Works matching AU Bujotzek, Alexander

EFFICIENT SIMULATION OF LIGAND–RECEPTOR BINDING PROCESSES USING THE CONFORMATION DYNAMICS APPROACH.

DNA-gesteuerte bivalente Präsentation von Liganden für den Östrogenrezeptor.

Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding.

Structural mechanism of Fab domain dissociation as a measure of interface stability.

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins.

Computational entropy estimation of linear polyether-modified surfaces and correlation with protein resistant properties of such surfaces.

Back-to-Germline (B2G) Procedure for Antibody Devolution.

Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope.

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins.

VH-VL orientation prediction for antibody humanization candidate selection: A case study.

MoFvAb: Modeling the Fv region of antibodies.

DNA-Controlled Bivalent Presentation of Ligands for the Estrogen Receptor.

ABlooper: fast accurate antibody CDR loop structure prediction with accuracy estimation.

Thera-SAbDab: the Therapeutic Structural Antibody Database.

Towards a rational spacer design for bivalent inhibition of estrogen receptor.

Antibodies exhibit multiple paratope states influencing V<sub>H</sub>–V<sub>L</sub> domain orientations.

ZIBgridfree: efficient conformational analysis by partition-of-unity coupling.

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities.

V<sub>H</sub>‐V<sub>L</sub> interdomain dynamics observed by computer simulations and NMR.

Prediction of VH-VL domain orientation for antibody variable domain modeling.

The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures.

Bispecific antibodies—effects of point mutations on CH3-CH3 interface stability.

Germline-Dependent Antibody Paratope States and Pairing Specific V<sub>H</sub>-V<sub>L</sub> Interface Dynamics.

Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.