Works matching DE "G protein coupled receptors"
Results: 5000
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.
- Published in:
- Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 362, doi. 10.1038/nsmb.3014
- By:
- Publication type:
- Article
Unraveling the structural basis of GPCR activation and inactivation.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 539, doi. 10.1038/nsmb.2584
- By:
- Publication type:
- Article
Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia.
- Published in:
- PLoS Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1371/journal.pbio.3003025
- By:
- Publication type:
- Article
Structure of G protein-coupled receptor GPR1 bound to full-length chemerin adipokine reveals a chemokine-like reverse binding mode.
- Published in:
- PLoS Biology, 2024, v. 22, n. 10, p. 1, doi. 10.1371/journal.pbio.3002838
- By:
- Publication type:
- Article
An atlas of Caenorhabditis elegans chemoreceptor expression.
- Published in:
- PLoS Biology, 2018, v. 16, n. 1, p. 1, doi. 10.1371/journal.pbio.2004218
- By:
- Publication type:
- Article
Las orexinas dos péptidos hipotalámicos: Su localización y acción en el eje hipotálamo-hipófisis-gónadas.
- Published in:
- Revista Mexicana de Neurociencia, 2014, v. 15, n. 6, p. 345
- By:
- Publication type:
- Article
The influence of alignment-free sequence representations on the semi-supervised classification of class C G protein-coupled receptors.
- Published in:
- Medical & Biological Engineering & Computing, 2015, v. 53, n. 2, p. 137, doi. 10.1007/s11517-014-1218-y
- By:
- Publication type:
- Article
Empathy, Target Distress, and Neurohormone Genes Interact to Predict Aggression for Others–Even Without Provocation.
- Published in:
- Personality & Social Psychology Bulletin, 2014, v. 40, n. 11, p. 1406, doi. 10.1177/0146167214549320
- By:
- Publication type:
- Article
Alared: Solvatochromic and Fluorogenic Red Amino Acid for Ratiometric Live‐Cell Imaging of Bioactive Peptides.
- Published in:
- Chemistry - A European Journal, 2024, v. 30, n. 35, p. 1, doi. 10.1002/chem.202401296
- By:
- Publication type:
- Article
Allosteric Tuning of Caspase‐7: Establishing the Nexus of Structure and Catalytic Power.
- Published in:
- Chemistry - A European Journal, 2023, v. 29, n. 40, p. 1, doi. 10.1002/chem.202300872
- By:
- Publication type:
- Article
Frontispiece: Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs.
- Published in:
- Chemistry - A European Journal, 2023, v. 29, n. 1, p. 1, doi. 10.1002/chem.202380163
- By:
- Publication type:
- Article
Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs.
- Published in:
- Chemistry - A European Journal, 2023, v. 29, n. 1, p. 1, doi. 10.1002/chem.202202565
- By:
- Publication type:
- Article
Transition‐Linker Containing Detergents for Membrane Protein Studies.
- Published in:
- Chemistry - A European Journal, 2022, v. 28, n. 69, p. 1, doi. 10.1002/chem.202202242
- By:
- Publication type:
- Article
Photochromic Fentanyl Derivatives for Controlled μ‐Opioid Receptor Activation.
- Published in:
- Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202201515
- By:
- Publication type:
- Article
Complex peptide macrocycle optimization: combining NMR restraints with conformational analysis to guide structure-based and ligand-based design.
- Published in:
- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 11, p. 519, doi. 10.1007/s10822-023-00524-2
- By:
- Publication type:
- Article
On the construction of LIECE models for the serotonin receptor 5-HT2AR.
- Published in:
- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 7, p. 313, doi. 10.1007/s10822-023-00507-3
- By:
- Publication type:
- Article
Computational insights into ligand–induced G protein and β-arrestin signaling of the dopamine D1 receptor.
- Published in:
- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 5/6, p. 227, doi. 10.1007/s10822-023-00503-7
- By:
- Publication type:
- Article
GPCRLigNet: rapid screening for GPCR active ligands using machine learning.
- Published in:
- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 3, p. 147, doi. 10.1007/s10822-023-00497-2
- By:
- Publication type:
- Article
Computational investigation of functional water molecules in GPCRs bound to G protein or arrestin.
- Published in:
- Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 2, p. 91, doi. 10.1007/s10822-022-00492-z
- By:
- Publication type:
- Article
Is there a common allosteric binding site for G-protein coupled receptors?
- Published in:
- Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 6, p. 405, doi. 10.1007/s10822-022-00454-5
- By:
- Publication type:
- Article
Binding site identification of G protein-coupled receptors through a 3D Zernike polynomials-based method: application to C. elegans olfactory receptors.
- Published in:
- Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 1, p. 11, doi. 10.1007/s10822-021-00434-1
- By:
- Publication type:
- Article
Benchmarking the performance of MM/PBSA in virtual screening enrichment using the GPCR-Bench dataset.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 11, p. 1133, doi. 10.1007/s10822-020-00339-5
- By:
- Publication type:
- Article
Addressing free fatty acid receptor 1 (FFAR1) activation using supervised molecular dynamics.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 11, p. 1181, doi. 10.1007/s10822-020-00338-6
- By:
- Publication type:
- Article
Benchmarking GPCR homology model template selection in combination with de novo loop generation.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 10, p. 1027, doi. 10.1007/s10822-020-00325-x
- By:
- Publication type:
- Article
Computational insights into the molecular mechanisms of differentiated allosteric modulation at the mu opioid receptor by structurally similar bitopic modulators.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 8, p. 879, doi. 10.1007/s10822-020-00309-x
- By:
- Publication type:
- Article
A Taxicab geometry quantification system to evaluate the performance of in silico methods: a case study on adenosine receptors ligands.
- Published in:
- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 6, p. 697, doi. 10.1007/s10822-020-00301-5
- By:
- Publication type:
- Article
A<sub>3</sub> adenosine receptor activation mechanisms: molecular dynamics analysis of inactive, active, and fully active states.
- Published in:
- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 11, p. 983, doi. 10.1007/s10822-019-00246-4
- By:
- Publication type:
- Article
The role of water and protein flexibility in the structure-based virtual screening of allosteric GPCR modulators: an mGlu<sub>5</sub> receptor case study.
- Published in:
- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 9, p. 787, doi. 10.1007/s10822-019-00224-w
- By:
- Publication type:
- Article
A benchmark study of loop modeling methods applied to G protein-coupled receptors.
- Published in:
- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 6, p. 573, doi. 10.1007/s10822-019-00196-x
- By:
- Publication type:
- Article
Evaluating the performance of MM/PBSA for binding affinity prediction using class A GPCR crystal structures.
- Published in:
- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 5, p. 487, doi. 10.1007/s10822-019-00201-3
- By:
- Publication type:
- Article
Enabling the hypothesis-driven prioritization of ligand candidates in big databases: Screenlamp and its application to GPCR inhibitor discovery for invasive species control.
- Published in:
- Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 3, p. 415, doi. 10.1007/s10822-018-0100-7
- By:
- Publication type:
- Article
"In silico" study of the binding of two novel antagonists to the nociceptin receptor.
- Published in:
- Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 2, p. 385, doi. 10.1007/s10822-017-0095-5
- By:
- Publication type:
- Article
Allosteric modulation model of the mu opioid receptor by herkinorin, a potent not alkaloidal agonist.
- Published in:
- Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 5, p. 467, doi. 10.1007/s10822-017-0016-7
- By:
- Publication type:
- Article
In search of novel ligands using a structure-based approach: a case study on the adenosine A receptor.
- Published in:
- Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 10, p. 863, doi. 10.1007/s10822-016-9963-7
- By:
- Publication type:
- Article
Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.
- Published in:
- Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 8, p. 625, doi. 10.1007/s10822-016-9937-9
- By:
- Publication type:
- Article
Molecular dynamics simulations and structure-based network analysis reveal structural and functional aspects of G-protein coupled receptor dimer interactions.
- Published in:
- Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 6, p. 489, doi. 10.1007/s10822-016-9919-y
- By:
- Publication type:
- Article
Modeling ligand recognition at the P2Y receptor in light of X-ray structural information.
- Published in:
- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 8, p. 737, doi. 10.1007/s10822-015-9858-z
- By:
- Publication type:
- Article
Improving homology modeling of G-protein coupled receptors through multiple-template derived conserved inter-residue interactions.
- Published in:
- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 5, p. 413, doi. 10.1007/s10822-014-9823-2
- By:
- Publication type:
- Article
A desirability function-based scoring scheme for selecting fragment-like class A aminergic GPCR ligands.
- Published in:
- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 1, p. 59, doi. 10.1007/s10822-014-9804-5
- By:
- Publication type:
- Article
Fitting and handling dose response data.
- Published in:
- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 1, p. 1, doi. 10.1007/s10822-014-9752-0
- By:
- Publication type:
- Article
Predicted 3D structures of olfactory receptors with details of odorant binding to OR1G1.
- Published in:
- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 12, p. 1175, doi. 10.1007/s10822-014-9793-4
- By:
- Publication type:
- Article
Computational chemogenomics: Is it more than inductive transfer?
- Published in:
- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 6, p. 597, doi. 10.1007/s10822-014-9743-1
- By:
- Publication type:
- Article
Scaffold mining of kinase hinge binders in crystal structure database.
- Published in:
- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 1, p. 13, doi. 10.1007/s10822-013-9700-4
- By:
- Publication type:
- Article
5-HT receptor pharmacophores to screen for off-target activity of α-adrenoceptor antagonists.
- Published in:
- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 4, p. 305, doi. 10.1007/s10822-013-9647-5
- By:
- Publication type:
- Article
Development of 7TM receptor-ligand complex models using ligand-biased, semi-empirical helix-bundle repacking in torsion space: application to the agonist interaction of the human dopamine D receptor.
- Published in:
- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 3, p. 277, doi. 10.1007/s10822-013-9640-z
- By:
- Publication type:
- Article
Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A, A, A, and A receptor antagonists.
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 11, p. 1247, doi. 10.1007/s10822-012-9612-8
- By:
- Publication type:
- Article
Predicting the effects of amino acid replacements in peptide hormones on their binding affinities for class B GPCRs and application to the design of secretin receptor antagonists.
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 7, p. 835, doi. 10.1007/s10822-012-9574-x
- By:
- Publication type:
- Article
Modeling activated states of GPCRs: the rhodopsin template.
- Published in:
- Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 437, doi. 10.1007/s10822-006-9061-3
- By:
- Publication type:
- Article
Anti-cancer strategies targeting the autotaxin-lysophosphatidic acid receptor axis: is there a path forward?
- Published in:
- 2021
- By:
- Publication type:
- Editorial