Works matching DE "RADIOLIGAND assay"

Results: 955

Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 419, doi. 10.1038/nsmb.2504

By:

Huang, Jianyun;
Chen, Shuai;
Zhang, J Jillian;
Huang, Xin-Yun

Publication type:

Article

A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 363, doi. 10.1038/nsmb.2500

By:

Xu, Rui;
Krause, Jens C;
McBride, Ryan;
Paulson, James C;
Crowe, James E;
Wilson, Ian A

Publication type:

Article

HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 90, doi. 10.1038/nsmb.2460

By:

Guce, Abigail I;
Mortimer, Sarah E;
Yoon, Taejin;
Painter, Corrie A;
Jiang, Wei;
Mellins, Elizabeth D;
Stern, Lawrence J

Publication type:

Article

Un-arrested development.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 5, p. 470, doi. 10.1038/nsmb.2299

By:

Finkelstein, Joshua M.

Publication type:

Article

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 424, doi. 10.1038/nsmb.2255

By:

Wang, Xiangxi;
Peng, Wei;
Ren, Jingshan;
Hu, Zhongyu;
Xu, Jiwei;
Lou, Zhiyong;
Li, Xumei;
Yin, Weidong;
Shen, Xinliang;
Porta, Claudine;
Walter, Thomas S;
Evans, Gwyndaf;
Axford, Danny;
Owen, Robin;
Rowlands, David J;
Wang, Junzhi;
Stuart, David I;
Fry, Elizabeth E;
Rao, Zihe

Publication type:

Article

Condensin structures chromosomal DNA through topological links.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 894, doi. 10.1038/nsmb.2087

By:

Cuylen, Sara;
Metz, Jutta;
Haering, Christian H.

Publication type:

Article

Flu BM2 structure and function.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 12, p. 1207, doi. 10.1038/nsmb1209-1207

By:

Cross, Timothy A.

Publication type:

Article

Structural and functional studies of ALIX interactions with YPXnL late domains of HIV-1 and EIAV.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 1, p. 43, doi. 10.1038/nsmb1319

By:

Qianting Zhai;
Fisher, Robert D.;
Hyo-Young Chung;
Myszka, David G.;
Sundquist, Wesley I.;
Hill, Christopher P.

Publication type:

Article

Molecular recognition of BMP-2 and BMP receptor IA.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 5, p. 481, doi. 10.1038/nsmb756

By:

Keller, Sascha;
Nickel, Joachim;
Jin-Li Zhang;
Sebald, Walter;
Mueller, Thomas D.

Publication type:

Article

Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 5, p. 459, doi. 10.1007/s10822-010-9362-4

By:

So-Jung Park;
Kufareva, Irina;
Abagyan, Ruben

Publication type:

Article

Using a homology model of cytochrome P450 2D6 to predict substrate site of metabolism.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 3, p. 237, doi. 10.1007/s10822-010-9336-6

By:

Unwalla, Rayomand J.;
Cross, Jason B.;
Salaniwal, Sumeet;
Shilling, Adam D.;
Leung, Louis;
Kao, John;
Humblet, Christine

Publication type:

Article

Fragment-based lead generation: identification of seed fragments by a highly efficient fragment screening technology.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 501, doi. 10.1007/s10822-009-9288-x

By:

Neumann, Lars;
Ritscher, Allegra;
Müller, Gerhard;
Hafenbradl, Doris

Publication type:

Article

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 491, doi. 10.1007/s10822-009-9283-2

By:

Landon, Melissa R.;
Lieberman, Raquel L.;
Hoang, Quyen Q.;
Shulin Ju;
Caaveiro, Jose M. M.;
Orwig, Susan D.;
Kozakov, Dima;
Brenke, Ryan;
Gwo-Yu Chuang;
Beglov, Dmitry;
Vajda, Sandor;
Petsko, Gregory A.;
Ringe, Dagmar

Publication type:

Article

Structural models in the assessment of protein druggability based on HTS data.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 583, doi. 10.1007/s10822-009-9279-y

By:

Gupta, Anvita;
Gupta, Arun Kumar;
Seshadri, Kothandaraman

Publication type:

Article

The multi-copy simultaneous search methodology: a fundamental tool for structure-based drug design.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 475, doi. 10.1007/s10822-009-9287-y

By:

Schubert, Christian R.;
Stultz, Collin M.

Publication type:

Article

A ligand’s-eye view of protein binding.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 6/7, p. 507, doi. 10.1007/s10822-008-9177-8

By:

Clark, Robert D.

Publication type:

Article

Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery.

Published in:

Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 1-3, p. 121, doi. 10.1007/s10822-007-9107-1

By:

Stewart, Kent D.;
Steffy, Kevin;
Harris, Kevin;
Harlan, John E.;
Stoll, Vincent S.;
Huth, Jeffrey R.;
Walter, Karl A.;
Gramling-Evans, Emily;
Mendoza, Renaldo R.;
Severin, Jean M.;
Richardson, Paul L.;
Barrett, Leo W.;
Matayoshi, Edmund D.;
Swift, Kerry M.;
Betz, Stephen F.;
Muchmore, Steve W.;
Kempf, Dale J.;
Molla, Akhter

Publication type:

Article

In-silico Screening using Flexible Ligand Binding Pockets: A Molecular Dynamics-based Approach.

Published in:

Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 4, p. 213, doi. 10.1007/s10822-005-4788-9

By:

Sivanesan, Dakshanamurthy;
Rajnarayanan, Rajendram V.;
Doherty, Jason;
Pattabiraman, Nagarajan

Publication type:

Article

A novel scoring function for molecular docking.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 9, p. 597, doi. 10.1023/B:JCAM.0000005766.95985.7e

By:

Muryshev, A. E.;
Tarasov, D. N.;
Butygin, A. V.;
Butygina, O. Yu.;
Aleksandrov, A. B.;
Nikitin, S. M.

Publication type:

Article

Vitamin D Assays: Past and Present Debates, Difficulties, and Developments.

Published in:

Calcified Tissue International, 2013, v. 92, n. 2, p. 118, doi. 10.1007/s00223-012-9693-3

By:

Fraser, William;
Milan, Anna

Publication type:

Article

Molecular properties of central and peripheral histamine H1 and H2 receptors.

Published in:

Pflügers Archiv: European Journal of Physiology, 2000, v. 439, n. 7, p. r131

By:

Čarman-Kr&zaron;an, Marija;
Lipnik-štangelj, Metoda

Publication type:

Article

Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.

Published in:

Archives of Gynecology & Obstetrics, 2012, v. 286, n. 6, p. 1577, doi. 10.1007/s00404-012-2476-2

By:

Boynukalin, Fazilet;
Esinler, Ibrahim;
Guven, Suleyman;
Gunalp, Serdar

Publication type:

Article

Serum Chorionic Gonadotropin Levels Determined by Radioreceptorassay and Early Diagnosis of Pregnancy in the Cynomolgus Monkey (Macaca fascicularis).

Published in:

American Journal of Primatology, 1987, v. 12, n. 1, p. 101, doi. 10.1002/ajp.1350120106

By:

Yoshida, Takashi;
Suzuki, Kinue;
Cho, Fumiaki;
Honjo, Shiceo

Publication type:

Article

Chemistry: Chemical con artists foil drug discovery.

Published in:

Nature, 2014, v. 513, n. 7519, p. 481, doi. 10.1038/513481a

By:

Baell, Jonathan;
Walters, Michael A.

Publication type:

Article

Synthesis and Characterization of a Cannabinoid Type 2 Receptor Photoactivated Prodrug.

Published in:

ChemPhotoChem, 2023, v. 7, n. 4, p. 1, doi. 10.1002/cptc.202200291

By:

Yin, Jiazhen;
Sharma, Raahul;
Tyndall, Joel D. A.;
Grimsey, Natasha L.;
Vernall, Andrea J.

Publication type:

Article

Association of Adenosine Receptor Gene Polymorphisms and In Vivo Adenosine A1 Receptor Binding in The Human Brain.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 13, p. 2989, doi. 10.1038/npp.2014.150

By:

Hohoff, Christa;
Garibotto, Valentina;
Elmenhorst, David;
Baffa, Anna;
Kroll, Tina;
Hoffmann, Alana;
Schwarte, Kathrin;
Zhang, Weiqi;
Arolt, Volker;
Deckert, Jürgen;
Bauer, Andreas

Publication type:

Article

[11C]-RO5013853: a New PET Radioligand for the Glycine Transporter TYPE 1.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 9, p. 2272, doi. 10.1038/npp.2014.52

By:

Wong, Dean;
Ostrowitzki, Susanne;
Zhou, Yun;
Alberati, Daniela;
Pinard, Emmanuel;
Raymont, Vanessa;
Martin-Facklam, Meret;
Hofmann, Carsten;
Parkar, Nikhat;
Brasic, James;
Hilton, John;
Dannals, Robert;
Borroni, Edilio

Publication type:

Article

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 4, p. 855, doi. 10.1038/npp.2009.194

By:

Leach, Katie;
Loiacono, Richard E.;
Felder, Christian C.;
McKinzie, David L.;
Mogg, Adrian;
Shaw, David B.;
Sexton, Patrick M.;
Christopoulos, Arthur

Publication type:

Article

Nicotinic Acetylcholine Receptors and Modulation of Learning in 4- and 27-Month-Old Rabbits.

Published in:

Neuropsychopharmacology, 2008, v. 33, n. 12, p. 2820, doi. 10.1038/npp.2008.1

By:

Jian-Guo Li;
Lehr, Melissa;
Lee-Yuan Liu-Chen;
Woodruff-Pak, Diana S.

Publication type:

Article

First Human Evidence of d-Amphetamine Induced Displacement of a D2/3 Agonist Radioligand: A [11C]-(+)-PHNO Positron Emission Tomography Study.

Published in:

Neuropsychopharmacology, 2008, v. 33, n. 2, p. 279, doi. 10.1038/sj.npp.1301400

By:

Willeit, Matthäus;
Ginovart, Nathalie;
Graff, Ariel;
Rusjan, Pablo;
Vitcu, Irina;
Houle, Sylvain;
Seeman, Philip;
Wilson, Alan A;
Kapur, Shitij

Publication type:

Article

Estimation of D2-like Receptor Occupancy by Dopamine in the Putamen of Hemiparkinsonian Monkeys.

Published in:

Neuropsychopharmacology, 2008, v. 33, n. 2, p. 270, doi. 10.1038/sj.npp.1301404

By:

Chefer, Svetlana I.;
Kimes, Alane S.;
Matochik, John A.;
Horti, Andrew G.;
Kurian, Varughese;
Shumway, Dean;
Domino, Edward F.;
London, Edythe D.;
Mukhin, Alexey G.

Publication type:

Article

Molecular Genetics of the Platelet Serotonin System in First-Degree Relatives of Patients with Autism.

Published in:

Neuropsychopharmacology, 2008, v. 33, n. 2, p. 353, doi. 10.1038/sj.npp.1301406

By:

Cross, Sarah;
Soo-Jeong Kim;
Weiss, Lauren A.;
Delahanty, Ryan J.;
Sutcliffe, James S.;
Leventhal, Bennett L.;
Cook Jr., Edwin H.;
Veenstra-VanderWeele, Jeremy

Publication type:

Article

1053 – In vitro receptor-binding profile of lurasidone and other commonly-used antipsychotics.

Published in:

2013

By:

Werner, P.;
Ishiyama, T.;
Loebel, A.;
Cucchiaro, J.;
Horisawa, T.;
Tokuda, K.;
Ogasa, M.;
Ishibashi, T.;
Stahl, S.M.

Publication type:

Abstract

Application of nano-baskets in preconcentration of tetrahedral oxoanions in the produced water of oil wells.

Published in:

Supramolecular Chemistry, 2012, v. 24, n. 12, p. 859, doi. 10.1080/10610278.2012.732225

By:

Mokhtari, Bahram;
Pourabdollah, Kobra

Publication type:

Article

Investigation of cancer cell lines for peptide receptor-targeted drug development.

Published in:

Journal of Drug Targeting, 2011, v. 19, n. 8, p. 719, doi. 10.3109/1061186X.2011.558089

By:

Sun, Lichun;
Luo, Jing;
Mackey, L. Vienna;
Morris, Lynsie M.;
Franko-Tobin, Laura G.;
LePage, Keith T.;
Coy, David H.

Publication type:

Article

Biological evaluation of avidin-based tumor pretargeting with DOTA-Triazole-Biotin constructed via versatile Cu(I) catalyzed click chemistry.

Published in:

Journal of Drug Targeting, 2011, v. 19, n. 6, p. 418, doi. 10.3109/1061186X.2010.504269

By:

Uppal, Jasleen Kaur;
Varshney, Raunak;
Hazari, Puja Panwar;
Chuttani, Krishna;
Kaushik, Narender Kumar;
Mishra, Anil Kumar

Publication type:

Article

Cycloalkaneindoles with 2-trifluoromethylimidazo[1,2- a]pyridin-6-yl fragment.

Published in:

Russian Journal of General Chemistry, 2015, v. 85, n. 6, p. 1452, doi. 10.1134/S1070363215060158

By:

Sokolov, V.;
Aksinenko, A.;
Epishina, T.;
Goreva, T.;
Gabrel'yan, A.;
Dranii, O.;
Grigor'ev, V.;
Bachurin, S.

Publication type:

Article

Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs.

Published in:

Frontiers in Psychiatry, 2022, v. 13, p. 1, doi. 10.3389/fpsyt.2022.1010501

By:

Sparkes, Eric;
Boyd, Rochelle;
Shuli Chen;
Markham, Jack W.;
Jia Lin Luo;
Foyzun, Tahira;
Zaman, Humayra;
Fletcher, Charlotte;
Ellison, Ross;
McGregor, Iain S.;
Santiago, Marina J.;
Lai, Felcia;
Gerona, Roy R.;
Connor, Mark;
Hibbs, David E.;
Cairns, Elizabeth A.;
Glass, Michelle;
Ametovski, Adam;
Banister, Samuel D.

Publication type:

Article

Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors.

Published in:

Diabetes, Obesity & Metabolism, 2012, v. 14, n. 1, p. 83, doi. 10.1111/j.1463-1326.2011.01517.x

By:

Grempler, R.;
Thomas, L.;
Eckhardt, M.;
Himmelsbach, F.;
Sauer, A.;
Sharp, D. E.;
Bakker, R. A.;
Mark, M.;
Klein, T.;
Eickelmann, P.

Publication type:

Article

Differential binding characteristics of native monomeric and polymeric immunoglobulin A1 (IgA1) on human mesangial cells and the influence of in vitro deglycosylation of IgA1 molecules.

Published in:

Clinical & Experimental Immunology, 2007, v. 148, n. 3, p. 507, doi. 10.1111/j.1365-2249.2007.03374.x

By:

Gao, Y.-H.;
Xu, L.-X.;
Zhang, J.-J.;
Zhang, Y.;
Zhao, M.-H.;
Wang, H.-Y.

Publication type:

Article

Longitudinal epitope analysis of insulin-binding antibodies in type 1 diabetes.

Published in:

Clinical & Experimental Immunology, 2006, v. 146, n. 1, p. 9, doi. 10.1111/j.1365-2249.2006.03178.x

By:

Hall, T. R.;
Thomas, J. W.;
Padoa, C. J.;
Torn, C.;
Landin-Olsson, M.;
Ortqvist, E.;
Hampe, C. S.

Publication type:

Article

The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass.

Published in:

EJNMMI Research, 2018, v. 8, n. 1, p. 1, doi. 10.1186/s13550-018-0465-6

By:

Jahan, Mahabuba;
Johnström, Peter;
Selvaraju, Ram K.;
Svedberg, Marie;
Winzell, Maria Sörhede;
Bernström, Jenny;
Kingston, Lee;
Schou, Magnus;
Jia, Zhisheng;
Skrtic, Stanko;
Johansson, Lars;
Korsgren, Olle;
Farde, Lars;
Halldin, Christer;
Eriksson, Olof

Publication type:

Article

Site-specific basicities regulate molecular recognition in receptor binding: in silico docking of thyroid hormones.

Published in:

European Biophysics Journal, 2013, v. 42, n. 9, p. 721, doi. 10.1007/s00249-013-0921-1

By:

Tóth, Gergő;
Baska, Ferenc;
Schretner, András;
Rácz, Ákos;
Noszál, Béla

Publication type:

Article

The effect of ligand affinity on integrins' lateral diffusion in cultured cells.

Published in:

European Biophysics Journal, 2013, v. 42, n. 4, p. 281, doi. 10.1007/s00249-012-0873-x

By:

Mainali, Dipak;
Smith, Emily

Publication type:

Article

General analysis of competitive binding in drug-interceptor-DNA systems.

Published in:

European Biophysics Journal, 2012, v. 41, n. 3, p. 273, doi. 10.1007/s00249-011-0783-3

By:

Buchelnikov, A.;
Santiago, A.;
Flores, M.;
Ramirez, R.;
Davies, D.;
Evstigneev, M.

Publication type:

Article

International standards for IgG and IgM anti-β2glycoprotein antibody measurement.

Published in:

Lupus, 2014, v. 23, n. 12, p. 1317, doi. 10.1177/0961203314544535

By:

Willis, R;
Grossi, C;
Orietta Borghi, M;
Martos-Sevilla, G;
Zegers, I;
Sheldon, J;
Meroni, PL

Publication type:

Article

Autoantibody profiling in APS.

Published in:

Lupus, 2014, v. 23, n. 12, p. 1262, doi. 10.1177/0961203314534305

By:

Roggenbuck, D;
Somma, V;
Schierack, P;
Borghi, MO;
Meroni, PL

Publication type:

Article

Binding Characteristics of Thyroid Hormone Distributor Proteins to Thyroid Hormone Metabolites.

Published in:

Thyroid, 2022, v. 32, n. 8, p. 990, doi. 10.1089/thy.2021.0588

By:

Jongejan, Rutchanna M.S.;
Meima, Marcel E.;
Visser, W. Edward;
Korevaar, Tim I.M.;
van den Berg, Sjoerd A.A.;
Peeters, Robin P.;
de Rijke, Yolanda B.

Publication type:

Article

A 99mTc-tricine-HYNIC-labeled Peptide Targeting the Melanocortin-1 Receptor for Melanoma Imaging.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 3, p. 349

By:

Shamshirian, Danial;
Erfani, Mostafa;
Beiki, Davood;
Hajiramazanali, Maliheh;
Fallahi, Babak

Publication type:

Article

Synthesis and Preliminary Evaluation of a New 99mTc Labeled Substance P Analogue as a Potential Tumor Imaging Agent.

Published in:

Iranian Journal of Pharmaceutical Research, 2015, v. 14, n. 1, p. 97

By:

Mozaffari, Saeed;
Erfani, Mostafa;
Beiki, Davood;
Daha, Fariba Johari;
Kobarfard, Farzad;
Balalaie, Saeed;
Fallahi, Babak

Publication type:

Article