Works matching IS 01676997 AND DT 2021 AND VI 39 AND IP 1

Results: 36
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    Efficacy of the eribulin, pertuzumab, and trastuzumab combination therapy for human epidermal growth factor receptor 2–positive advanced or metastatic breast cancer: a multicenter, single arm, phase II study (JBCRG-M03 study).

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 217, doi. 10.1007/s10637-020-00991-6
    By:
    • Yamashita, Toshinari;
    • Kawaguchi, Hidetoshi;
    • Masuda, Norikazu;
    • Kitada, Masahiro;
    • Narui, Kazutaka;
    • Hattori, Masaya;
    • Yoshinami, Tetsuhiro;
    • Matsunami, Nobuki;
    • Yanagihara, Kazuhiro;
    • Kawasoe, Teru;
    • Nagashima, Takeshi;
    • Bando, Hiroko;
    • Yano, Hiroshi;
    • Hasegawa, Yoshie;
    • Nakamura, Rikiya;
    • Kashiwaba, Masahiro;
    • Morita, Satoshi;
    • Ohno, Shinji;
    • Toi, Masakazu
    Publication type:
    Article
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    Erlotinib and bevacizumab in elderly patients ≥75 years old with non-small cell lung cancer harboring epidermal growth factor receptor mutations.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 210, doi. 10.1007/s10637-020-00988-1
    By:
    • Aoshima, Yoichiro;
    • Karayama, Masato;
    • Inui, Naoki;
    • Yasui, Hideki;
    • Hozumi, Hironao;
    • Suzuki, Yuzo;
    • Furuhashi, Kazuki;
    • Fujisawa, Tomoyuki;
    • Enomoto, Noriyuki;
    • Nakamura, Yutaro;
    • Mikamo, Masashi;
    • Matsuura, Shun;
    • Kusagaya, Hideki;
    • Kaida, Yusuke;
    • Uto, Tomohiro;
    • Hashimoto, Dai;
    • Matsui, Takashi;
    • Asada, Kazuhiro;
    • Suda, Takafumi
    Publication type:
    Article
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    Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 98, doi. 10.1007/s10637-020-00987-2
    By:
    • Mohamed, Magda F.;
    • Sroor, Farid M.;
    • Ibrahim, Nada S.;
    • Salem, Ghada S.;
    • El-Sayed, Hadeer H.;
    • Mahmoud, Marwa M.;
    • Wagdy, Menna-Allah M.;
    • Ahmed, Amina M.;
    • Mahmoud, Aya-Allah T.;
    • Ibrahim, Somia S.;
    • Ismail, Mariam M.;
    • Eldin, Sanaa Mohy;
    • Saleh, Fatma M.;
    • Hassaneen, Hamdi M.;
    • Abdelhamid, Ismail A.
    Publication type:
    Article
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    A phase I study of intraperitoneal paclitaxel combined with gemcitabine plus nab-paclitaxel for pancreatic cancer with peritoneal metastasis.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 175, doi. 10.1007/s10637-020-00982-7
    By:
    • Takahara, Naminatsu;
    • Nakai, Yousuke;
    • Ishigami, Hironori;
    • Saito, Kei;
    • Sato, Tatsuya;
    • Hakuta, Ryunosuke;
    • Ishigaki, Kazunaga;
    • Saito, Tomotaka;
    • Hamada, Tsuyoshi;
    • Mizuno, Suguru;
    • Kogure, Hirofumi;
    • Yamashita, Hiroharu;
    • Isayama, Hiroyuki;
    • Seto, Yasuyuki;
    • Koike, Kazuhiko
    Publication type:
    Article
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    A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 163, doi. 10.1007/s10637-020-00975-6
    By:
    • Shapiro, Geoffrey I.;
    • LoRusso, Patricia;
    • Cho, Daniel C.;
    • Musib, Luna;
    • Yan, Yibing;
    • Wongchenko, Matthew;
    • Chang, Ilsung;
    • Patel, Premal;
    • Chan, Iris T.;
    • Sanabria-Bohorquez, Sandra;
    • Meng, Raymond D.;
    • Bendell, Johanna C.
    Publication type:
    Article
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    Acute tubulointerstitial nephritis induced by the tyrosine kinase inhibitor vandetanib.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 237, doi. 10.1007/s10637-020-00973-8
    By:
    • Pilco Teran, Melissa;
    • Merino Ribas, Ana;
    • Martin Alemany, Nadia;
    • Barros Freiria, Xoana;
    • Rubio Casadevall, Jordi;
    • Pérez Bueno, Ferran;
    • García Méndez, Isabel;
    • Castillo Devia, Marcela;
    • Noboa Paez, Cristina;
    • Torguet Escuder, Pere;
    • Calabia Martínez, Jordi
    Publication type:
    Article
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    Extrahepatic metabolism of ibrutinib.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 1, doi. 10.1007/s10637-020-00970-x
    By:
    • Rood, Johannes J. M.;
    • Jamalpoor, Amer;
    • van Hoppe, Stephanie;
    • van Haren, Matthijs J.;
    • Wasmann, Roeland E.;
    • Janssen, Manoe J.;
    • Schinkel, Alfred H.;
    • Masereeuw, Rosalinde;
    • Beijnen, Jos H.;
    • Sparidans, Rolf W.
    Publication type:
    Article
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    Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors.

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 142, doi. 10.1007/s10637-020-00962-x
    By:
    • Eads, Jennifer R.;
    • Krishnamurthi, Smitha S.;
    • Saltzman, Joel;
    • Bokar, Joseph A.;
    • Savvides, Panos;
    • Meropol, Neal J.;
    • Gibbons, Joseph;
    • Koon, Henry;
    • Sharma, Neelesh;
    • Rogers, Lisa;
    • Pink, John J.;
    • Xu, Yan;
    • Beumer, Jan H.;
    • Riendeau, John;
    • Fu, Pingfu;
    • Gerson, Stanton L.;
    • Dowlati, Afshin
    Publication type:
    Article
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    The safety and tolerability of epacadostat alone and in combination with pembrolizumab in patients with advanced solid tumors: results from a first-in-Japanese phase I study (KEYNOTE-434).

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 152, doi. 10.1007/s10637-020-00942-1
    By:
    • Doi, Toshihiko;
    • Fujiwara, Yutaka;
    • Shitara, Kohei;
    • Shimizu, Toshio;
    • Yonemori, Kan;
    • Matsubara, Nobuaki;
    • Ohno, Izumi;
    • Kogawa, Takahiro;
    • Naito, Yoichi;
    • Leopold, Lance;
    • Munteanu, Mihaela;
    • Yatsuzuka, Naoyoshi;
    • Han, Shi Rong;
    • Samkari, Ayman;
    • Yamamoto, Noboru
    Publication type:
    Article
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    Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC).

    Published in:
    Investigational New Drugs, 2021, v. 39, n. 1, p. 182, doi. 10.1007/s10637-020-01000-6
    By:
    • Hecht, J. Randolph;
    • Papadopoulos, Kyriakos P.;
    • Falchook, Gerald S.;
    • Patel, Manish R.;
    • Infante, Jeffrey R.;
    • Aljumaily, Raid;
    • Wong, Deborah J.;
    • Autio, Karen A.;
    • Wainberg, Zev A.;
    • Bauer, Todd M.;
    • Javle, Milind;
    • Pant, Shubham;
    • Bendell, Johanna;
    • Hung, Annie;
    • Ratti, Navneet;
    • VanVlasselaer, Peter;
    • Verma, Rakesh;
    • Leveque, Joseph;
    • Rao, Sujata;
    • Oft, Martin
    Publication type:
    Article