Works matching IS 01676997 AND DT 2016 AND VI 34 AND IP 5

Results: 15

In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 541, doi. 10.1007/s10637-016-0359-2

By:

Salustiano, Eduardo;
Dumas, Matheus;
Silva-Santos, Gabriel;
Netto, Chaquip;
Costa, Paulo;
Rumjanek, Vivian

Publication type:

Article

Pharmacokinetics and excretion of C-omacetaxine in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 565, doi. 10.1007/s10637-016-0360-9

By:

Nijenhuis, Cynthia;
Hellriegel, Edward;
Beijnen, Jos;
Hershock, Diane;
Huitema, Alwin;
Lucas, Luc;
Mergui-Roelvink, Marja;
Munteanu, Mihaela;
Rabinovich-Guilatt, Laura;
Robertson, Philmore;
Rosing, Hilde;
Spiegelstein, Ofer;
Schellens, Jan

Publication type:

Article

Intravitreal vascular endothelial growth factor (VEGF) inhibitor injection in unrecognised early pregnancy.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 650, doi. 10.1007/s10637-016-0361-8

By:

Kianersi, Farzan;
Ghanbari, Heshmatollah;
Naderi Beni, Zahra;
Naderi Beni, Afsaneh

Publication type:

Article

Prediction of response to everolimus in neuroendocrine tumors: evaluation of clinical, biological and histological factors.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 654, doi. 10.1007/s10637-016-0363-6

By:

Benslama, Noura;
Bollard, Julien;
Vercherat, Cécile;
Massoma, Patrick;
Roche, Colette;
Hervieu, Valérie;
Peron, Julien;
Lombard-Bohas, Catherine;
Scoazec, Jean-Yves;
Walter, Thomas

Publication type:

Article

Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 663, doi. 10.1007/s10637-016-0366-3

By:

Lennon, Jennifer;
Butini, Stefania;
Campiani, Giuseppe;
O'Meara, Anne;
Williams, D.;
Zisterer, Daniela

Publication type:

Article

Phase I trial of dacomitinib, a pan-human epidermal growth factor receptor (HER) inhibitor, with concurrent radiotherapy and cisplatin in patients with locoregionally advanced squamous cell carcinoma of the head and neck (XDC-001).

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 575, doi. 10.1007/s10637-016-0367-2

By:

Prawira, Amy;
Brana-Garcia, Irene;
Spreafico, Anna;
Hope, Andrew;
Waldron, John;
Razak, Albiruni;
Chen, Eric;
Jang, Raymond;
O'Sullivan, Brian;
Giuliani, Meredith;
Bayley, Andrew;
Cho, John;
Wang, Lisa;
Perez-Ordonez, Bayardo;
Weinreb, Ilan;
Siu, Lillian;
Hansen, Aaron

Publication type:

Article

Phase II evaluation of LY2603618, a first-generation CHK1 inhibitor, in combination with pemetrexed in patients with advanced or metastatic non-small cell lung cancer.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 625, doi. 10.1007/s10637-016-0368-1

By:

Scagliotti, Giorgio;
Kang, Jin;
Smith, David;
Rosenberg, Richard;
Park, Keunchil;
Kim, Sang-We;
Su, Wu-Chou;
Boyd, Thomas;
Richards, Donald;
Novello, Silvia;
Hynes, Scott;
Myrand, Scott;
Lin, Ji;
Smyth, Emily;
Wijayawardana, Sameera;
Lin, Aimee;
Pinder-Schenck, Mary

Publication type:

Article

Intravenous and intraperitoneal paclitaxel with S-1 for treatment of refractory pancreatic cancer with malignant ascites.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 636, doi. 10.1007/s10637-016-0369-0

By:

Takahara, Naminatsu;
Isayama, Hiroyuki;
Nakai, Yousuke;
Ishigami, Hironori;
Satoi, Sohei;
Mizuno, Suguru;
Kogure, Hirofumi;
Matsubara, Saburo;
Yamamoto, Natsuyo;
Yamaguchi, Hironori;
Tada, Minoru;
Kitayama, Joji;
Watanabe, Toshiaki;
Koike, Kazuhiko

Publication type:

Article

A phase I dose-escalation study of LY2875358, a bivalent MET antibody, given as monotherapy or in combination with erlotinib or gefitinib in Japanese patients with advanced malignancies.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 584, doi. 10.1007/s10637-016-0370-7

By:

Yoh, Kiyotaka;
Doi, Toshihiko;
Ohmatsu, Hironobu;
Kojima, Takashi;
Takahashi, Hideaki;
Zenke, Yoshitaka;
Wacheck, Volker;
Enatsu, Sotaro;
Nakamura, Takashi;
Turner, Kellie;
Uenaka, Kazunori

Publication type:

Article

Phase I dose-finding study of monotherapy with atezolizumab, an engineered immunoglobulin monoclonal antibody targeting PD-L1, in Japanese patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 596, doi. 10.1007/s10637-016-0371-6

By:

Mizugaki, Hidenori;
Yamamoto, Noboru;
Murakami, Haruyasu;
Kenmotsu, Hirotsugu;
Fujiwara, Yutaka;
Ishida, Yoshimasa;
Kawakami, Tomohisa;
Takahashi, Toshiaki

Publication type:

Article

Molecular and cellular effects of a novel hydroxamate-based HDAC inhibitor - belinostat - in glioblastoma cell lines: a preliminary report.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 552, doi. 10.1007/s10637-016-0372-5

By:

Kusaczuk, Magdalena;
Krętowski, Rafał;
Stypułkowska, Anna;
Cechowska-Pasko, Marzanna

Publication type:

Article

A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 604, doi. 10.1007/s10637-016-0374-3

By:

Rosen, Lee;
LoRusso, Patricia;
Ma, Wen;
Goldman, Jonathan;
Weise, Amy;
Colevas, A.;
Adjei, Alex;
Yazji, Salim;
Shen, Angela;
Johnston, Stuart;
Hsieh, Hsin-Ju;
Chan, Iris;
Sikic, Branimir

Publication type:

Article

A phase I trial of the aurora kinase inhibitor , ENMD-2076, in patients with relapsed or refractory acute myeloid leukemia or chronic myelomonocytic leukemia.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 614, doi. 10.1007/s10637-016-0375-2

By:

Yee, Karen;
Chen, Hsiao-Wei;
Hedley, David;
Chow, Sue;
Brandwein, Joseph;
Schuh, Andre;
Schimmer, Aaron;
Gupta, Vikas;
Sanfelice, Deborah;
Johnson, Tara;
Le, Lisa;
Arnott, Jamie;
Bray, Mark;
Sidor, Carolyn;
Minden, Mark

Publication type:

Article

The renal effects of ALK inhibitors.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 643, doi. 10.1007/s10637-016-0379-y

By:

Izzedine, Hassan;
El-Fekih, Rania;
Perazella, Mark

Publication type:

Article

The aurora kinase inhibitor VX-680 shows anti-cancer effects in primary metastatic cells and the SW13 cell line.

Published in:

Investigational New Drugs, 2016, v. 34, n. 5, p. 531, doi. 10.1007/s10637-016-0358-3

By:

Pezzani, Raffaele;
Rubin, Beatrice;
Bertazza, Loris;
Redaelli, Marco;
Barollo, Susi;
Monticelli, Halenya;
Baldini, Enke;
Mian, Caterina;
Mucignat, Carla;
Scaroni, Carla;
Mantero, Franco;
Ulisse, Salvatore;
Iacobone, Maurizio;
Boscaro, Marco

Publication type:

Article