Works matching DE "ENZYME inhibitors"

Results: 5000

Furanyl-Chalcones as antimalarial agent: synthesis, in vitro study, DFT, and docking analysis of PfDHFR inhibition.

Published in:

Pure & Applied Chemistry, 2025, v. 97, n. 6, p. 673, doi. 10.1515/pac-2024-0330

By:

Wulan, Fia Fathiana;
Pranaya, Rachelio Clorozenta;
Jecky;
Nadira, Intan;
Astuti, Endang;
Prasetyo, Niko;
Wahyuningsih, Tutik Dwi

Publication type:

Article

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00431-2

By:

Kong, Keyu;
Liu, Li;
Zhang, Renfang;
Chang, Yongyun;
Shao, Yueming;
Zhao, Chen;
Qiao, Hua;
Jin, Minghao;
Chen, Xuzhuo;
Shi, Wentao;
Wu, Xinru;
Fan, Wenxuan;
Hu, Yuehao;
Rong, Kewei;
Zhang, Pu;
Li, Baixing;
Zhang, Jingwei;
Ma, Peixiang;
Zhang, Xiaoling;
Li, Huiwu

Publication type:

Article

Synthesis, Structure, and Biological Activity of a Novel Diterpenoid Isosteviol-12,17-Sulfonic Ester Derivative.

Published in:

Chemistry of Natural Compounds, 2025, v. 61, n. 3, p. 478, doi. 10.1007/s10600-025-04682-7

By:

Liu, Cong-Jun;
Qiang, Ke-Jia;
Guo, Ling-Yan;
Wang, Yong;
Wang, Wei;
Chen, Han;
Min, Yu-Tao;
Li, Yu-Ling;
Wang, Yu-Fei

Publication type:

Article

Comprehensive review of enzymes (protease, lipase) in milk: Impact on storage quality, detection methods, and control strategies.

Published in:

Comprehensive Reviews in Food Science & Food Safety, 2025, v. 24, n. 3, p. 1, doi. 10.1111/1541-4337.70164

By:

Khan, Mati Ullah;
Yu, Pengfei;
Wu, Yuyin;
Chen, Zhiwei;
Kong, Ling;
Farid, Anum;
Cui, Jiaqi;
Yang, Jun

Publication type:

Article

Short Tandem Repeat (STR) Somatic Mutation in Non-Melanoma Skin Cancer (NMSC): Association with Transcriptomic Profile and Potential Implications for Therapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1669, doi. 10.3390/cancers17101669

By:

Kibriya, Muhammad G.;
Almazan, Armando;
Argos, Maria;
Islam, Tariqul;
Shea, Christopher R.;
Ahsan, Habibul;
Jasmine, Farzana

Publication type:

Article

Clinical Characteristics and Survival of Ovarian Cancer Patients According to Homologous Recombination Deficiency Status.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1628, doi. 10.3390/cancers17101628

By:

Sisman, Yagmur;
Schejbel, Lone;
Schnack, Tine Henrichsen;
Høgdall, Claus;
Høgdall, Estrid

Publication type:

Article

Ectopic Cushing's Syndrome in Advanced Small-Cell Lung Cancer (SCLC): Clinical Challenges and Therapeutic Insights.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1611, doi. 10.3390/cancers17101611

By:

Gamrat-Żmuda, Aleksandra;
Minasyan, Mari;
Wysocki, Piotr J.;
Hubalewska-Dydejczyk, Alicja;
Gilis-Januszewska, Aleksandra

Publication type:

Article

A Novel Camel Milk-Derived Peptide LLPK Improves Glucose-Lipid Metabolism in db / db Mice via PPAR Signaling Pathway.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1693, doi. 10.3390/nu17101693

By:

Han, Binsong;
Ye, Yuhui;
Zhang, Cunzheng;
Zhang, Lina;
Zhou, Peng

Publication type:

Article

Insights into the potential role of BMSCs-exo delivered USP14 on SIRT1 deubiquitination in Staphylococcus aureus-induced model of osteomyelitis.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05898-7

By:

Yu, Jun;
Yang, Ming;
Jin, Yun;
Yang, Kaijie;
Yang, Haibo

Publication type:

Article

Patients' report of statins use and side-effects in a sample of hospitalized cardiac patients in the Islamic Republic of Iran.

Published in:

Eastern Mediterranean Health Journal, 2011, v. 17, n. 5, p. 460, doi. 10.26719/2011.17.5.460

By:

Mashayekhi, S. O.;
Ghandforoush-Sattari, M.;
Baghdadchi, M. E.;
Kheyri, M.

Publication type:

Article

Cardiovascular Toxicity of Biologic Agents for Cancer Therapy.

Published in:

Oncology (08909091), 2014, v. 28, n. 6, p. 482

By:

BHAVE, MANALI;
AKHTER, NAUSHEEN;
ROSEN, STEVEN T.

Publication type:

Article

Do Oncogenic Drivers Exist in Squamous Cell Carcinoma of the Lung?

Published in:

Oncology (08909091), 2013, v. 27, n. 9, p. 906

By:

VILLARUZ, LIZA C.;
BURNS, TIMOTHY F.;
SOCINSKI, MARK A.

Publication type:

Article

Clinical Applications of The Cancer Genome Atlas Project (TCGA) for Squamous Cell Lung Carcinoma.

Published in:

Oncology (08909091), 2013, v. 27, n. 9, p. 899

By:

DEVARAKONDA, SIDDHARTHA;
MORGENSZTERN, DANIEL;
GOVINDAN, RAMASWAMY

Publication type:

Article

EUTOS Score Validated for Predicting Treatment Outcomes With TKI Therapy.

Published in:: Oncology (08909091), 2013, v. 27, n. 8, p. 814
Publication type:: Article

Improving Disease Burden in Myelofibrosis: Changing the Natural History of the Disease.

Published in:

Oncology (08909091), 2013, v. 27, n. 7, p. 715

By:

MESA, RUBEN A.

Publication type:

Article

First-Line Treatment for Patients With CML in Chronic Phase: Why Imatinib Is an Appropriate Choice.

Published in:

Oncology (08909091), 2013, v. 27, n. 8, p. 780

By:

SCHIFFER, CHARLES A.

Publication type:

Article

First-Line Treatment for Patients With CML in Chronic Phase: Second-Generation TKIs Are the Therapy of Choice.

Published in:

Oncology (08909091), 2013, v. 27, n. 8, p. 781

By:

CORTES, JORGE

Publication type:

Article

Ruxolitinib for Myelofibrosis: From 'Palliation' to Prolongation of Survival.

Published in:

Oncology (08909091), 2013, v. 27, n. 7, p. 717

By:

VERSTOVSEK, SRDAN

Publication type:

Article

Clarifying the Use of Ruxolitinib in Patients With Myelofibrosis.

Published in:

Oncology (08909091), 2013, v. 27, n. 7, p. 706

By:

KREMYANSKAYA, MARINA;
ATALLAH, EHAB L.;
HOFFMAN, RONALD;
MASCARENHAS, JOHN O.

Publication type:

Article

Improving Harmonious Precision.

Published in:

Oncology (08909091), 2012, v. 26, n. 10, p. 949

By:

Kim, Joseph W.;
Marshall, John L.

Publication type:

Article

Targeted Therapy: Its Status and Promise in Selected Solid Tumors Part I: Areas of Major Impact.

Published in:

Oncology (08909091), 2012, v. 26, n. 10, p. 936

By:

Wu, Jennifer;
Joseph, Sasha O.;
Muggia, Franco M.

Publication type:

Article

Early results of mTOR inhibitor for triple-negative breast cancer.

Published in:: Oncology (08909091), 2012, v. 26, n. 10, p. 931
Publication type:: Article

Is Imatinib Still an Acceptable First-Line Treatment for CML in Chronic Phase?

Published in:

Oncology (08909091), 2012, v. 26, n. 10, p. 901

By:

Goldman, John M.;
Marin, David

Publication type:

Article

First-Line Erlotinib Inferior to Chemo in Advanced Lung Cancer.

Published in:: Oncology (08909091), 2012, v. 26, n. 10, p. 930
Publication type:: Article

Which TKI Should Be Recommended as Initial Treatment for CML in Chronic Phase?

Published in:

2012

By:

Schiffer, Charles A.

Publication type:

Opinion

Front-Line TKI Therapy for Chronic-Phase CML: the Luxury of Choice.

Published in:

2012

By:

Shah, Neil P.

Publication type:

Opinion

The Maze of PARP Inhibitors in Ovarian Cancer.

Published in:

Oncology (08909091), 2012, v. 26, n. 2, p. 136

By:

Nair, Abhilasha;
Chen, Alice P.

Publication type:

Article

A Step Forward Toward Better Characterization of Ovarian Cancer.

Published in:: Oncology (08909091), 2012, v. 26, n. 2, p. 169
Publication type:: Article

The Circuitous Path of PARP Inhibitor Development in Epithelial Ovarian Cancer.

Published in:

Oncology (08909091), 2012, v. 26, n. 2, p. 144

By:

Pothuri, Bhavana

Publication type:

Article

PARP Inhibition in Epithelial Ovarian Cancer: High Hopes Undergo a Reality Check.

Published in:

Oncology (08909091), 2012, v. 26, n. 2, p. 128

By:

Zorn, Kristin K.

Publication type:

Article

FDA Approves Vemurafenib for Treatment of Metastatic Melanoma.

Published in:: Oncology (08909091), 2011, v. 25, n. 10, p. 906
Publication type:: Article

Screening Identifies Mechanisms of Drug Resistance to PI3K Inhibitors.

Published in:: Oncology (08909091), 2011, v. 25, n. 11, p. 1
Publication type:: Article

PARP Inhibitors in Breast Cancer: BRCA and Beyond.

Published in:

Oncology (08909091), 2011, v. 25, n. 11, p. 1

By:

Rios, Jorge;
Puhalla, Shannon

Publication type:

Article

PARP Inhibitors and Their Evolving Role in Breast Cancer.

Published in:

2011

By:

Roop, Ryan P.;
Ma, Cynthia X.;
Ellis, Matthew J. C.

Publication type:

Opinion

PARP Inhibitors: the Story is Still Unfolding.

Published in:

2011

By:

Tripathy, Debu

Publication type:

Opinion

The Future of NSCLC: Molecular Profiles Guiding Treatment Decisions.

Published in:

Oncology (08909091), 2011, v. 25, n. 7, p. 607

By:

TSAO, ANNE S.;
PAPADIMITRAKOPOULOU, VASSILIKI A.

Publication type:

Article

ALK-Targeted Therapy for Lung Cancer: Ready for Prime Time.

Published in:

Oncology (08909091), 2011, v. 25, n. 7, p. 597

By:

HUSAIN, HATIM;
RUDIN, CHARLES M.

Publication type:

Article

ALK-Targeted Therapy in NSCLC: Likely to Be of Benefit but Not Quite Ready for Prime Time.

Published in:

Oncology (08909091), 2011, v. 25, n. 7, p. 601

By:

SOCINSKI, MARK A.

Publication type:

Article

Current Concepts in the Diagnosis and Management of Small-Cell Lung Cancer.

Published in:

Oncology (08909091), 2010, v. 24, n. 11, p. 1034

By:

Ganti, Apar Kishor;
West, William W.;
Lackner, Rudy P.;
Kessinger, Anne

Publication type:

Article

Metabolic Syndrome After Hormone-Modifying Therapy: Risks Associated With Antineoplastic Therapy.

Published in:

Oncology (08909091), 2010, v. 24, n. 9, p. 839

By:

Redig, Amanda J.;
Munshi, Hidayatullah G.

Publication type:

Article

Drug Essentials mTOR Inhibitors.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 43

By:

Wilkes, Gail M.

Publication type:

Article

The Lancet/Karp Article Reviewed.

Published in:

Oncology (08909091), 2005, v. 19, n. 8, p. 1049

By:

Stone, Richard M.

Publication type:

Article

The Lancet/Karp Article Reviewed.

Published in:

Oncology (08909091), 2005, v. 19, n. 8, p. 1053

By:

Cortes, Jorge E.

Publication type:

Article

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 604, doi. 10.1038/nsmb.2021

By:

Nguyen, Tina T.;
Shih-Chung Chang;
Evnouchidou, Irini;
York, Ian A.;
Zikos, Christos;
Rock, Kenneth L.;
Goldberg, Alfred L.;
Stratikos, Efstratios;
Stern, Lawrence J.

Publication type:

Article

Structural basis of Fic-mediated adenylylation.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 8, p. 1004, doi. 10.1038/nsmb.1867

By:

Junyu Xiao;
Worby, Carolyn A.;
Mattoo, Seema;
Sankaran, Banumathi;
Dixon, Jack E.

Publication type:

Article

Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 3, p. 264, doi. 10.1038/nsmb.1751

By:

Chao, Luke H.;
Pellicena, Patricia;
Deindl, Sebastian;
Barclay, Lauren A.;
Schulman, Howard;
Kuriyan, John

Publication type:

Article

Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1094, doi. 10.1038/nsmb.1488

By:

Xin Geng;
Yong Shi;
Nakagawa, Akihisa;
Yoshina, Sawako;
Mitani, Shohei;
Yigong Shi;
Ding Xue

Publication type:

Article

Jamming the ratchet of transcription.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 8, p. 777, doi. 10.1038/nsmb0808-777

By:

Svetlov, Vladimir;
Nudler, Evgeny

Publication type:

Article

Structural basis for the catalytic mechanism of phosphothreonine lyase.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 1, p. 101, doi. 10.1038/nsmb1329

By:

Linjie Chen;
Huayi Wang;
Jie Zhang;
Lichuan Gu;
Niu Huang;
Jian-Min Zhou;
Jijie Chai

Publication type:

Article

Structure-based design of a pathway-specific nuclear import inhibitor.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 452, doi. 10.1038/nsmb1229

By:

Cansizoglu, Ahmet E.;
Lee, Brittany J.;
Zi Chao Zhang;
Fontoura, Beatriz M. A.;
Yuh Min Chook

Publication type:

Article