Results
Title

A new E-ring γ-lactone pentacyclic triterpene from Lysimachia clethroides and its cytotoxic activities.

Authors

Xu, Qiong-ming; Liu, Yan-li; Feng, Yu-lin; Tang, Li-hua; Yang, Shi-lin

Abstract

A new E-ring γ-lactone pentacyclic triterpene, 3β-myristoxyurs-12-en-19,28-olide, has been isolated from the chloroform extract of Lysimachia clethroides Duby, together with four known pentacyclic triterpenoid acids. The structures of the compounds were elucidated by comprehensive spectroscopic analyses. All of the compounds showed various degrees of cytotoxic activities in MTT assay.

Subjects

ORGANIC synthesis; LACTONES; TRITERPENES; LYSIMACHIA; CELL-mediated cytotoxicity; TRITERPENOIDS; SPECTRUM analysis; CHEMICAL structure

Publication

Chemistry of Natural Compounds, 2012, Vol 48, Issue 4, p597

ISSN

0009-3130

Publication type

Academic Journal

DOI

10.1007/s10600-012-0321-2