Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Multiple intramolecular triggers converge to preferential G protein coupling in the CB<sub>2</sub>R.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60003-0

By:

Morales-Pastor, Adrian;
Miljuš, Tamara;
Dieguez-Eceolaza, Miguel;
Stępniewski, Tomasz Maciej;
Ledesma-Martin, Vicente;
Heydenreich, Franziska M.;
Flock, Tilman;
Plouffe, Bianca;
Le Gouill, Christian;
Duchaine, Jean;
Sykes, David A.;
Nicholson, Colin;
Koers, Eline J.;
Guba, Wolfgang;
Rufer, Arne C.;
Grether, Uwe;
Bouvier, Michel;
Veprintsev, Dmitry B.;
Selent, Jana

Publication type:

Article

Base‐Mediated [4+1] Annulation Strategy for Modular Assembly of Alkynyl/Carboxylated Dihydrobenzofurans.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401455

By:

Kong, Yangzilin;
Wu, Yinsong;
Liu, Yanan;
Fei, Binbin;
Wu, Mengdi;
Gu, Ni;
Tang, Qiang;
He, Xinwei

Publication type:

Article

Synthesis and Functionalization of Aziridines: A Perspective View from Pharmaceutical Industries.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejoc.202401414

By:

Ju, Xuan;
Lee, Miseon;
Leung, Joyce C.;
Lee, Jaehee

Publication type:

Article

Recent approaches for the synthesis of phosphonopyrroles (microreview).

Published in:

Chemistry of Heterocyclic Compounds, 2025, v. 61, n. 1, p. 48, doi. 10.1007/s10593-025-03395-7

By:

Abaid, Kmar;
Touil, Soufiane

Publication type:

Article

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 32, p. 1, doi. 10.1002/chem.202500855

By:

Taguchi, Akihiro;
Sakata, Megumi;
Yamamoto, Ryusei;
Shida, Hayate;
Kuraishi, Saeka;
Konno, Sho;
Takayama, Kentaro;
Taniguchi, Atsuhiko;
Hayashi, Yoshio

Publication type:

Article

Nickel‐Catalyzed Umpolung Difluoroalkylation of Imines Enables General Access to β‐Difluoroalkylated Amines.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202500990

By:

Tong, Fei‐Fei;
Feng, Xiao‐Tian;
Han, Yuan‐Zhan;
Huang, Ming‐Chen;
Zhao, Hai‐Yang;
Zhang, Xingang

Publication type:

Article

Direct Conversion of Aromatic Lactones into Bioisosteres by Carbonyl‐to‐Boranol Exchange.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202500921

By:

Zhang, Yu;
Lu, Hong;
Chang, Jie;
Xu, Peng‐Fei;
Li, Hang;
Jin, Yuan;
Wei, Hao

Publication type:

Article

NMR-driven structure-based drug discovery by unveiling molecular interactions.

Published in:

Communications Chemistry, 2025, v. 8, p. 1, doi. 10.1038/s42004-025-01542-x

By:

Platzer, Gerald;
Mayer, Moriz;
McConnell, Darryl B.;
Konrat, Robert

Publication type:

Article

Exploring the neuroprotective mechanisms of Jiawei Suanzaoren decoction in depression: insights from network pharmacology and molecular docking.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04939-2

By:

Ma, Ruiting;
Zhang, Wenjing;
Chen, Lixia;
Tong, Lijun

Publication type:

Article

Correction: Comparative study on drug encapsulation and release kinetics in extracellular vesicles loaded with snake venom L - amino acid oxidase.

Published in:

2025

By:

Ramesh, Divya;
Bakkannavar, Shankar M.;
Bhat, Vinutha R.;
Pai, K. Sreedhara Ranganath;
Sharan, Krishna

Publication type:

Correction Notice

Controlling Protein Functionalities With Temporal and Cellular/Subcellular Dimensions of Spatial Resolution With Molecular Photoswitches.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 4, p. 1142, doi. 10.1002/med.22106

By:

Sahu, Saugata;
Amrutha, Ammathnadu S.;
Tamaoki, Nobuyuki

Publication type:

Article

Comparative Analysis of the Efficacy of Beta-Blockers in the Treatment of Chronic Heart Failure Based on Methods of Attribute Statistics and Drug Interaction Analysis.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 86, doi. 10.1007/s11094-025-03367-3

By:

Zhukova, O. V.;
Shimanovsky, N. L.

Publication type:

Article

Water-Soluble Analogs of Palmitoylethanolamide and Its Combination with Adamantane- and Phenylcyclohexyl-Containing Glutamate Blockers.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 9, doi. 10.1007/s11094-025-03357-5

By:

Gmiro, V. E.;
Serdyuk, S. E.

Publication type:

Article

Significant Achievements of Experimental Pharmacology and Neurology That Were Not Crowned by Success in the Clinic, and Not Only (Review).

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 1, p. 1, doi. 10.1007/s11094-025-03356-6

By:

Mirzoyan, R. S.

Publication type:

Article

A VISIT TO THE MUSEUM OF PHARMACY IN KRAKÓW, POLAND.

Published in:

HerbalGram, 2025, n. 143, p. 34

By:

Gafner, Stefan;
Szopa, Agnieszka;
Rzepiela, Agnieszka

Publication type:

Article

Exploring the wound healing potential of Ixora coccinea and Rhododendron arboreum formulation: integrating experimental and computational approaches.

Published in:

Journal of Complementary & Integrative Medicine, 2025, v. 22, n. 2, p. 304, doi. 10.1515/jcim-2024-0232

By:

Bharathy, Pavithra;
Thanikachalam, Punniyakoti Veeraveedu;
Moses, Allen Christopher;
Balakrishnan, Dinesh Kumar

Publication type:

Article

Flow electrooxidation of chiral alcohols with high enantioselectivity via integrated metal‐organic frameworks and aminoxyl radicals.

Published in:

AIChE Journal, 2025, v. 71, n. 7, p. 1, doi. 10.1002/aic.18847

By:

Ren, Linhan;
Li, Jiayuan;
Li, Suiqin;
Li, Kai;
Wang, Yuhang;
Wang, Jieyu;
Chen, Ying;
He, Jiahui;
Zhong, Xing;
Wang, Jianguo

Publication type:

Article

Simultaneous enantioselective determination of 2-, 3-, and 4-methylmethcathinones; their isomers; and major phase-1 metabolites in oral fluid of drug abusers using enantioselective high-performance liquid chromatography-tandem mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 15, p. 3231, doi. 10.1007/s00216-025-05838-8

By:

Kobidze, Giorgi;
Faro, Alfredo Fabrizio Lo;
Balloni, Aurora;
Sprega, Giorgia;
Massano, Marta;
Wille, Sarah M. R.;
Basile, Giuseppe;
Farkas, Tivadar;
Tini, Anastasio;
Busardò, Francesco Paolo;
Chankvetadze, Bezhan

Publication type:

Article

Imidazole Hybrids: A Privileged Class of Heterocycles in Medicinal Chemistry with New Insights into Anticancer Activity.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2245, doi. 10.3390/molecules30102245

By:

Murtazaeva, Zarifa;
Nasrullaev, Azizbek;
Buronov, Anvarjon;
Gaybullaev, Shukhrat;
Nie, Lifei;
Numonov, Sodik;
Khushnazarov, Zohidjon;
Turgunov, Davron;
Kuryazov, Rustamkhon;
Zhao, Jiangyu;
Bozorov, Khurshed

Publication type:

Article

High-Risk Neuroblastoma Stage 4 (NBS4): Developing a Medicinal Chemistry Multi-Target Drug Approach.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2211, doi. 10.3390/molecules30102211

By:

Gerges, Amgad;
Canning, Una

Publication type:

Article

Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01557-4

By:

Maspero, Elena;
Cappa, Anna;
Weber, Janine;
Trifirò, Paolo;
Amici, Raffaella;
Bruno, Agostino;
Fagà, Giovanni;
Cecatiello, Valentina;
Fattori, Raimondo;
Leuzzi, Brian;
Taibi, Vincenzo;
Meroni, Giuseppe;
Pasi, Maurizio;
Romussi, Alessia;
Sartori, Luca;
Villa, Manuela;
Vultaggio, Stefania;
Cirò, Marco;
Soffientini, Paolo;
Lombardo, Lierin

Publication type:

Article

A Path Forward for Extended-Release Buprenorphine—Optimizing Implementation Strategies.

Published in:

2025

By:

Assoumou, Sabrina A.;
Morgan, Jake R.

Publication type:

Opinion

Efficient Synthesis of Tetrasubstituted Furans via Lipase-Catalyzed One-Pot Sequential Multicomponent Reaction.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 482, doi. 10.3390/catal15050482

By:

Zeng, Yongqi;
Tang, Yong;
Xu, Minglu;
Wang, Dantong;
Wang, Zhi;
Gao, Yin;
Wang, Lei

Publication type:

Article

Recent Advances in the Synthesis of Quinolines: A Focus on Oxidative Annulation Strategies.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 441, doi. 10.3390/catal15050441

By:

Liao, Mao-Lin;
Liu, Peng-Peng;
Yang, Jia-Cheng;
Li, Ping-Gui;
Zou, Liang-Hua

Publication type:

Article

Unveiling the Reaction Pathway of Oxidative Aldehyde Deformylation by a MOF-Based Cytochrome P450 Mimic.

Published in:

Catalysts (2073-4344), 2025, v. 15, n. 5, p. 436, doi. 10.3390/catal15050436

By:

Luo, Zehua;
Zhou, Wentian;
Chen, Junying;
Li, Yingwei

Publication type:

Article

Illuminating innovation: the AAPS Open editorial series of AAPS fellows and awardees.

Published in:

2025

By:

Su, Yongchao;
Ronaldson, Patrick;
Kumar, M. N. V. Ravi

Publication type:

Editorial

Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 655, doi. 10.3390/pharmaceutics17050655

By:

Petrov, Gleb V.;
Koldina, Alena M.;
Ledenev, Oleg V.;
Tumasov, Vladimir N.;
Nazarov, Aleksandr A.;
Syroeshkin, Anton V.

Publication type:

Article

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 636, doi. 10.3390/pharmaceutics17050636

By:

Amenta, Arianna;
Nordio, Giulia;
Piazzola, Francesco;
Di Paolo, Maria Luisa;
Milani, Fabio;
Giacomini, Martina;
Citarella, Andrea;
Ciriello, Umberto;
Paladino, Giuseppe;
Pellegrino, Sara;
Silvestri, Federica;
Fasano, Valerio;
Dalla Via, Lisa;
Passarella, Daniele

Publication type:

Article

From Patterns to Pills: How Informatics Is Shaping Medicinal Chemistry.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 612, doi. 10.3390/pharmaceutics17050612

By:

Trachtenberg, Alexander;
Akabayov, Barak

Publication type:

Article

Medicinal Chemistry Strategies in Targeting TGF-βR1 Kinase Domain: Unveiling Insights into Inhibitor Structure–Activity Relationship (SAR).

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 716, doi. 10.3390/ph18050716

By:

Babiker, Nusaiba A.;
Nadeem, Soam;
Abu Kariem, Hasan;
Abdul Hameed, Afra;
Negmeldin, Ahmed T.;
El-labbad, Eman M.

Publication type:

Article

Nitropyridines in the Synthesis of Bioactive Molecules.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 692, doi. 10.3390/ph18050692

By:

Starosotnikov, Alexey;
Bastrakov, Maxim

Publication type:

Article

Beyond Exosomes: An Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform for Reprogramming Immune Suppression in Metastatic Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1658, doi. 10.3390/cancers17101658

By:

Gutierrez-Sandoval, Ramon;
Gutiérrez-Castro, Francisco;
Muñoz-Godoy, Natalia;
Rivadeneira, Ider;
Sobarzo, Adolay;
Iturra, Jordan;
Krakowiak, Francisco;
Alarcón, Luis;
Dorado, Wilson;
Lagos, Andy;
Montenegro, Diego;
Muñoz, Ignacio;
Aguilera, Rodrigo;
Toledo, Andres

Publication type:

Article

Gum Rosin in Medical and Pharmaceutical Applications: From Conventional Uses to Modern Advancements.

Published in:

Materials (1996-1944), 2025, v. 18, n. 10, p. 2266, doi. 10.3390/ma18102266

By:

Siboro, Sonita Afrita Purba;
Salma, Sabrina Aufar;
Syuhada;
Putri, Kurnia Sari Setio;
Yuliati, Frita;
Lee, Won-Ki;
Lim, Kwon-Taek

Publication type:

Article

Recent Developments and Perspectives in Palladium‐Catalyzed Multi‐Component Reactions.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 19, p. 1, doi. 10.1002/ejoc.202401429

By:

Rinu, Pulluparambil Xavier Thresia;
Saranya, Salim;
Anilkumar, Gopinathan

Publication type:

Article

Extended Family of Thiophosphoryl-Appended Pd(II) Pincer Complexes with a Deprotonated Amide Core: Synthesis and Biological Evaluation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4536, doi. 10.3390/ijms26104536

By:

Aleksanyan, Diana V.;
Churusova, Svetlana G.;
Konovalov, Aleksandr V.;
Rybalkina, Ekaterina Yu.;
Laletina, Lidia A.;
Ryzhmanova, Yana V.;
Nelyubina, Yulia V.;
Soloveva, Svetlana A.;
Lyubimov, Sergey E.;
Peregudov, Alexander S.;
Klemenkova, Zinaida S.;
Kozlov, Vladimir A.

Publication type:

Article

Vanadium 8-hydroxyquinoline derivatives in medicine: current state and future outlook.

Published in:

BioMetals, 2025, v. 38, n. 3, p. 711, doi. 10.1007/s10534-025-00683-9

By:

Kohanfekr, Tahmineh;
Gholamrezazadeh, Camelia;
Hosseini, Hasan Ali

Publication type:

Article

The effect and mechanism of Germacrone in ameliorating alcoholic fatty liver by inhibiting Nrf2/Rbp4.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01132-y

By:

Xiao, Ru;
Fang, Jiamin;
Huang, Qinpo;
He, Guolin;
Ou, Xia;
De, Yang;
Gui, Shuhua;
Zhang, Yun;
Wang, Maoci;
Zhong, Yiyuan;
Zeren, Dawa;
Long, Yongling;
Liu, Changhui;
Xiong, Tianqin

Publication type:

Article

Integrated bioinformatics and network pharmacology to identify and validate macrophage polarization related hub genes in the treatment of osteoarthritis with Astragalus membranaceus.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05799-9

By:

Zang, Hui;
Wang, Liuyan;
Wu, Yang;
Chang, Junfei;
Liu, Wanjun

Publication type:

Article

BIOLOGICAL PROPERTIES AND MULTIFUNCTIONAL APPLICATIONS OF BENZYLPIPERIDINE DERIVATIVES (REVIEW).

Published in:

News of Kazakhstan Science / Novosti nauki Kazahstana, 2025, n. 1, p. 45, doi. 10.53939/1560-5655_2025_1_45

By:

A. A., Sergazy;
А. B., Kaldybayeva;
А. Е., Malmakova;
K. S., Tassibekov;
V. K., Yu

Publication type:

Article

尼秦类新精神活性物质的质谱特征研究.

Published in:

Journal of Chinese Mass Spectrometry Society, 2025, v. 46, n. 3, p. 334, doi. 10.7538/zpxb.2024.0129

By:

邓乾亚;
徐金伦;
倪春芳;
曹芳琦;
斯洋;
何思阳;
郑水庆;
梁晨

Publication type:

Article

Ehrungen, Karriere.

Published in:: Nachrichten aus der Chemie, 2025, v. 73, n. 6, p. 65, doi. 10.1002/nadc.20254151265
Publication type:: Article

Investigating inspection practices of pharmaceutical manufacturing facilities in selected Arab countries: views of inspectors and pharmaceutical industry employees.

Published in:

Eastern Mediterranean Health Journal, 2013, v. 19, n. 11, p. 919, doi. 10.26719/2013.19.11.919

By:

Garg, S.;
Hasan, R.;
Scahill, S.;
Babar, Z. Ud-Din

Publication type:

Article

Molecular mechanism of Codonopsis pilosula in the prevention and treatment of immune thrombocytopenia based on network pharmacology and molecular docking.

Published in:

Chinese Nursing Research, 2024, v. 38, n. 9, p. 1505, doi. 10.12102/j.issn.1009-6493.2024.09.001

By:

ZHU Ruifang;
CHEN Yulu;
WANG Qian;
ZHANG Jun;
ZHANG Shuwen;
LYU Yaru;
HAN Shifan;
WANG Hongwei

Publication type:

Article

GD2抗体达妥昔单抗β 治疗神经母细胞瘤护理专家共识.

Published in:

Chinese Nursing Research, 2024, v. 38, n. 6, p. 941, doi. 10.12102/j.issn.1009-6493.2024.06.001

By:

王春立;
武莹;
何梦雪;
苏玲;
张洪燕;
郭欣;
程方方;
李丹;
孙丹;
王翠

Publication type:

Article

基于网络药理学和分子对接技术探讨沙棘活性成分对非酒精性脂肪肝作用机制

Published in:

Chinese Nursing Research, 2023, v. 37, n. 16, p. 2853, doi. 10.12102/j.issn.1009-6493.2023.16.001

By:

高健;
吴胜男;
王晓静;
纪景馨;
张然;
程景民

Publication type:

Article

Think Twice Before Prescribing Custom-Compounded Bioidentical Hormone Therapy.

Published in:

2014

By:

Pinkerton, JoAnn V.

Publication type:

Journal Article

Risks and Effectiveness of Compounded Bioidentical Hormone Therapy: A Case Series.

Published in:

2014

By:

Davis, Ruth;
Batur, Pelin;
Thacker, Holly L

Publication type:

Journal Article

High Throughput Screening Retools for the Future.

Published in:

Bio-IT World, 2009, v. 8, n. 1, p. 20

By:

Glaser, Vicki

Publication type:

Article

THE SEARCH FOR Unusual Suspects.

Published in:: Bio-IT World, 2008, v. 7, n. 1, p. 26
Publication type:: Article

Software Solutions for MEDICINAL CHEMISTRY.

Published in:

Bio-IT World, 2007, v. 6, n. 3, p. 22

By:

Glaser, Vicki

Publication type:

Article