- Title
Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats.
- Authors
Novoseletskaya, A.; Kiseleva, N.; Zimina, I.; Bystrova, O.; Belova, O.; Inozemtsev, A.; Arion, V.; Sergienko, V.
- Abstract
We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective.
- Subjects
THYMUS; THYMUS hyperplasia; LYMPHOID tissue; ENDOCRINE glands; COGNITIVE structures
- Publication
Bulletin of Experimental Biology & Medicine, 2015, Vol 159, Issue 5, p623
- ISSN
0007-4888
- Publication type
Academic Journal
- DOI
10.1007/s10517-015-3030-6