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Title

Study of Hepatoprotective Effects of Xymedon.

Authors

Vyshtakalyuk, A.; Nazarov, N.; Zueva, I.; Lantsova, A.; Minnekhanova, O.; Busygin, D.; Porfiryev, A.; Evtyugin, V.; Reznik, V.; Zobov, V.

Abstract

Xymedon (1-(β-oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxopyrimidine), a regeneratory and wound-healing drug, exhibited hepatoprotective activity in laboratory animals with experimental toxic hepatitis. Oral drug reduced the severity of toxic involvement of the liver induced by CCl and reduced animal mortality. Xymedon promoted recovery of the blood biochemical parameters characterizing the liver status.

Subjects

HETEROCYCLIC compounds; ORGANIC cyclic compounds; WOUND healing; HEPATITIS treatment; LIVER disease treatment; PHYSIOLOGY

Publication

Bulletin of Experimental Biology & Medicine, 2013, Vol 155, Issue 5, p643

ISSN

0007-4888

Publication type

Academic Journal

DOI

10.1007/s10517-013-2215-0

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