The article presents the results of studies of the level regime of Lake Balkhash, which has a characteristic, consisting in the change in the average lake horizon, the changes in the magnitudes of the seasonal and inter-annual amplitudes of the levels, as well as their annual and long-term ones. All this involves the change in the lake table area and its outline on the map. The results of full-scale data of modern morphometric characteristics are presented, on the basis of which the actual map of the lake depths is presented. The impact of economic activity on the fluctuations of the long-term annual average water level in the lake is observed, and the analysis of the changes in the hydro chemical composition of the water depending on the level of the lake is given.