Results
Title

Degradation of hydrochlorothiazide in water.

Authors

Brigante, M.; DellaGreca, M.; Previtera, L.; Rubino, M.; Temussi, F.

Abstract

The photolytic decomposition of hydrochlorothiazide in water was investigated. Irradiation of the drug was performed in pure water and sewage treatment plant water with a solar simulator and by direct sunlight. Here we show that three photoproducts were obtained. Two of them were formed in yields much higher than 10%. An environmental risk assessment of hydrochlorothiazide should take into account also these photoproducts in a complete analytical and ecotoxicological evaluation.

Subjects

CHEMICAL decomposition; AZIDES; IRRADIATION; WATER; SUNSHINE; ENVIRONMENTAL risk assessment

Publication

Environmental Chemistry Letters, 2005, Vol 2, Issue 4, p195

ISSN

1610-3653

Publication type

Academic Journal

DOI

10.1007/s10311-004-0096-1