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- Title
Degradation of hydrochlorothiazide in water.
- Authors
Brigante, M.; DellaGreca, M.; Previtera, L.; Rubino, M.; Temussi, F.
- Abstract
The photolytic decomposition of hydrochlorothiazide in water was investigated. Irradiation of the drug was performed in pure water and sewage treatment plant water with a solar simulator and by direct sunlight. Here we show that three photoproducts were obtained. Two of them were formed in yields much higher than 10%. An environmental risk assessment of hydrochlorothiazide should take into account also these photoproducts in a complete analytical and ecotoxicological evaluation.
- Subjects
CHEMICAL decomposition; AZIDES; IRRADIATION; WATER; SUNSHINE; ENVIRONMENTAL risk assessment
- Publication
Environmental Chemistry Letters, 2005, Vol 2, Issue 4, p195
- ISSN
1610-3653
- Publication type
Academic Journal
- DOI
10.1007/s10311-004-0096-1