Works matching DE "GENE regulatory networks"

Results: 5000

Bioinformatics analysis of comorbid mechanisms between ischemic stroke and end stage renal disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-01049-4

By:

Wang, Shuhong;
Li, Zhongda;
Wang, Xiao;
Zhou, Jiexue;
Meng, Shandong;
Zhuang, Jinyang;
Zhou, Yan;
Zhao, Qin;
Zhu, Chunli;
Zhang, Yusheng;
Shen, Sheng

Publication type:

Article

The identification and validation of histone acetylation-related biomarkers in depression disorder based on bioinformatics and machine learning approaches.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1479616

By:

Zhang, Lu;
Lv, YuJing;
Ma, Mengqing;
Lv, Jile;
Chen, Jie;
Lei, Shang;
Man, Yi;
Xing, Guimei;
Wang, Yu

Publication type:

Article

Integrating single-cell sequencing and transcriptome analysis to unravel the mechanistic role of sialylation-related genes in sepsis-induced acute respiratory distress syndrome.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1528769

By:

Liu, Xiaobing;
Huang, Yake;
Zhang, Hao;
Yang, Xia;
Liu, Quanxing;
Dai, Jigang

Publication type:

Article

Identification of potential crucial genes and mechanisms associated with metabolically unhealthy obesity based on the gene expression profile.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1540721

By:

Wang, Qingqing;
Wang, Silu;
Zhuang, Zhanyu;
Wu, Xueting;
Gao, Hongkun;
Zhang, Tianyi;
Zou, Guorong;
Ge, Xing;
Liu, Yapeng

Publication type:

Article

Identification immune-related hub genes in diagnosing atherosclerosis with ischemic stroke through comprehensive bioinformatics analysis and machine learning.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1507855

By:

Zhang, Ming;
Tang, Li-Jun;
Long, Shi-Yu

Publication type:

Article

Mechanistic role of pyroptosis in Kawasaki disease: An integrative bioinformatics analysis of immune dysregulation, machine learning-based biomarker discovery, WGCNA, and drug repurposing insights.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323597

By:

Wang, Chen;
Wu, Qinchao;
Chen, Jie;
Wang, Jun;
Li, Dan

Publication type:

Article

Neutrophil extracellular traps-related genes contribute to sepsis-associated acute kidney injury.

Published in:

BMC Nephrology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12882-025-04126-y

By:

Shaoqun, Tang;
Xi, Yu;
Wei, Wang;
Yaru, Luo;
Shaoqing, Lei;
Zhen, Qiu;
Yanlin, Yang;
Qian, Sun;
Zhongyuan, Xia

Publication type:

Article

1 H-NMR Guided Isolation of Bioactive Compounds from Species of the Genus Piper.

Published in:

Molecules, 2025, v. 30, n. 9, p. 2020, doi. 10.3390/molecules30092020

By:

Oliveira, Celso R.;
Burroughs, Megan J.;
Richards, Lora A.;
Dyer, Lee A.;
Urbano-Muñoz, Federico;
Lee, Camryn;
Warner, Megan;
Dodson, Craig D.;
Wallace, Ian S.;
Jeffrey, Christopher S.

Publication type:

Article

MYCN as an oncogene in pediatric brain tumors.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1584978

By:

Fernandez Garcia, Adriana;
Jackson, Jayden;
Iyer, Poorvi;
Oliver, Elissa G.;
Funato, Kosuke

Publication type:

Article

Comprehensive Single‐Cell RNA Sequencing Analysis of Cervical Cancer: Insights Into Tumor Microenvironment and Gene Expression Dynamics.

Published in:

International Journal of Genomics, 2025, v. 2025, p. 1, doi. 10.1155/ijog/5027347

By:

Shen, Xiaoting;
Sun, Huier;
Zhang, Shanshan;
Zhao, Songyun

Publication type:

Article

Combined Transcriptomic and Mendelian Randomisation Explores the Diagnostic Value of Ubiquitination-Related Genes in Sepsis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 4709, doi. 10.2147/JIR.S489077

By:

Bai, Xue;
Liu, RuXing;
Tang, Yujiao;
Yang, LiTing;
Niu, Zesu;
Hu, Yi;
Zhang, Ling;
Chen, MengFei

Publication type:

Article

An Integrative Analysis of Transcriptome Combined with Machine Learning and Single-Cell RNA-Seq for the Common Biomarkers in Crohn's Disease and Kidney Stone Disease.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 4961, doi. 10.2147/JIR.S502513

By:

Zhu, Jiejie;
Du, Yishan;
Gao, Luyao;
Wang, Jiajia;
Mei, Qiao

Publication type:

Article

ABA Enhances Drought Resistance During Rapeseed (Brassica napus L.) Seed Germination Through the Gene Regulatory Network Mediated by ABA Insensitive 5.

Published in:

Plants (2223-7747), 2025, v. 14, n. 9, p. 1276, doi. 10.3390/plants14091276

By:

Luo, Dan;
Huang, Qian;
Chen, Manyi;
Li, Haibo;
Lu, Guangyuan;
Feng, Huimin;
Lv, Yan

Publication type:

Article

The Transcriptome Analysis Provides New Insights into Signaling for Bamboo Shoot Development of Sympodial Bamboo.

Published in:

Foods, 2025, v. 14, n. 9, p. 1647, doi. 10.3390/foods14091647

By:

Hu, Shunkai;
Dong, Mengran;
Guo, Qirong

Publication type:

Article

Comparative Proteome and Weighted Gene Co-Expression Network Analyses Uncover the Mechanism of Wheat Grain Protein Accumulation in Response to Nitrogen Fertilizer Application.

Published in:

Foods, 2025, v. 14, n. 9, p. 1481, doi. 10.3390/foods14091481

By:

Xu, Beiming;
Jia, Yuku;
Feng, Jianchao;
Yang, Yang;
Ma, Geng;
Zhang, Yanfei;
Xie, Yingxin;
Ma, Dongyun

Publication type:

Article

The Mitochondrial Metabolism Gene ECH1 Was Identified as a Novel Biomarker for Diabetic Nephropathy: Using Bioinformatics Analysis and Experimental Confirmation.

Published in:

Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2025, v. 18, p. 1087, doi. 10.2147/DMSO.S494644

By:

Miao, Yan;
Yan, Lei;
Cao, Huixia;
Jiao, Xiaojing;
Shao, Fengmin

Publication type:

Article

STAT3, MYC, and EBNA1 cooperate through a ZC3H18 transcriptional network to regulate survival and proliferation of EBV-positive lymphomas.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013166

By:

Xu, Huanzhou;
Koganti, Siva;
Li, Chenglong;
McIntosh, Michael T.;
Bhaduri-McIntosh, Sumita

Publication type:

Article

Transcriptomics-based exploration of ubiquitination-related biomarkers and potential molecular mechanisms in laryngeal squamous cell carcinoma.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02148-x

By:

Chen, Qiu;
Wu, Zhimin;
Ma, Yifei

Publication type:

Article

Construction of a Prognostic Model for Cervical Cancer Related to lncRNA Based on Differential Co-expression Network and Functional Study of Key Gene EGFR-AS1.

Published in:

Journal of Cancer, 2025, v. 16, n. 7, p. 2321, doi. 10.7150/jca.108429

By:

Kailong Du;
Qian Chen;
Hui Fan;
Yunlong Lei;
Jian Zhang

Publication type:

Article

Structural Dynamics, Evolutionary Significance, and Functions of Really Interesting New Gene Proteins in Ubiquitination and Plant Stress: A Review.

Published in:

DNA & Cell Biology, 2025, v. 44, n. 5, p. 214, doi. 10.1089/dna.2025.0002

By:

Agarwal, Parinita;
Chittora, Anjali;
Verma, Ayushi;
Agarwal, Pradeep K.

Publication type:

Article

Development of a prognostic model for osteosarcoma based on macrophage polarization-related genes using machine learning: implications for personalized therapy.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-024-01530-w

By:

Zeng, Jin;
Wang, Dong;
Tong, ZhaoChen;
Li, ZiXin;
Wang, GuoWei;
Du, YuMeng;
Li, Jinsong;
Miao, Jinglei;
Chen, Shijie

Publication type:

Article

Integrating genomics and transcriptomics reveals candidate genes affecting loin muscle area in Huaxi cattle.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322026

By:

Xue, Qingqing;
Du, Lili;
Deng, Tianyu;
Liang, Mang;
Li, Keanning;
Qian, Li;
Qiu, Shiyuan;
Chen, Yan;
Gao, Xue;
Xu, Lingyang;
Wang, Zezhao;
Zheng, Caihong;
Zhang, Lupei;
Li, Junya;
Gao, Huijiang

Publication type:

Article

Patient-specific gene co-expression networks reveal novel subtypes and predictive biomarkers in lung adenocarcinoma.

Published in:

NPJ Systems Biology & Applications, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41540-025-00522-0

By:

López-Sánchez, Patricio;
Ávila-Moreno, Federico;
Hernández-Lemus, Enrique;
Kuijjer, Marieke L.;
Espinal-Enríquez, Jesús

Publication type:

Article

Identification and Validation of Tryptophan Metabolism–Related Genes in Diabetic Kidney Disease and Construction of a Clinical Prediction Model.

Published in:

Journal of Diabetes Research, 2025, v. 2025, p. 1, doi. 10.1155/jdr/2736801

By:

Liu, Shaojie;
Jiang, Qingqing;
Li, Wenli;
Shi, Jinbao;
Wu, Binxuan;
Xiong, Man;
Huang, Liuying;
Ahmed, Syed Anees

Publication type:

Article

Integrative bioinformatic analysis identifies differentially expressed gene targets as potential biomarkers for anaplastic thyroid cancer.

Published in:

Journal of the Egyptian National Cancer Institute, 2025, v. 37, n. 1, p. 1, doi. 10.1186/s43046-025-00282-2

By:

Treviño-Juarez, Angel Sebastian;
Gonzalez-Gonzalez, Jose Gerardo;
Rodriguez-Gutierrez, Rene;
Sanchez-Garcia, Adriana;
Gonzalez-Velazquez, Camilo Daniel

Publication type:

Article

Decoding microRNA arm switching: a key to evolutionary innovation and gene regulation.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05663-3

By:

Pinhal, Danillo;
Gonçalves, Leandro de B.;
Campos, Vinícius F.;
Patton, James G.

Publication type:

Article

KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma.

Published in:

Nature Communications, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41467-025-59503-w

By:

Mihalas, Anca B.;
Arora, Sonali;
O'Connor, Samantha A.;
Feldman, Heather M.;
Cucinotta, Christine E.;
Mitchell, Kelly;
Bassett, John;
Kim, Dayoung;
Jin, Kang;
Hoellerbauer, Pia;
Delegard, Jennifer;
Ling, Melissa;
Jenkins, Wesley;
Kufeld, Megan;
Corrin, Philip;
Carter, Lucas;
Tsukiyama, Toshio;
Aronow, Bruce;
Plaisier, Christopher L.;
Patel, Anoop P.

Publication type:

Article

The assembly of a Malus sieversii regulatory network reveals gene resistance against Alternaria alternata f. sp. mali when colonized by Trichoderma biofertilizer.

Published in:

Journal of Plant Research, 2025, v. 138, n. 3, p. 483, doi. 10.1007/s10265-025-01622-y

By:

Ji, Shida;
Li, Dechen;
Yao, Jin;
Liu, Bin;
Han, Jing;
Wang, Yucheng;
Liu, Zhihua

Publication type:

Article

Identification of Common miRNAs Differentially Expressed in Periodontitis and Pancreatic Cancer.

Published in:

In Vivo, 2025, v. 39, n. 3, p. 1422, doi. 10.21873/invivo.13944

By:

SUNNETCI-AKKOYUNLU, DENIZ;
UGURTAS, CANSU;
KULCU-SARIKAYA, NURHAN;
OZER, TOLGAHAN;
CINE, NACI;
EREN-KESKIN, SEDA;
KANLI, AYLIN;
SAVLI, HAKAN

Publication type:

Article

Decoding serotonin: the molecular symphony behind depression.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1572462

By:

Shu, Yue;
Tian, Lei;
Wang, Xing;
Meng, Tinyang;
Yu, Shouyang;
Li, Yulan

Publication type:

Article

Identification and Correlation of Novel Genes Associated with Progression of Alzheimer's Disease.

Published in:

Gene Expression (1052-2166), 2025, v. 24, n. 2, p. 84, doi. 10.14218/GE.2023.00143

By:

Arora, Tania;
Jain, Puneet;
Sharma, Harshita;
Prashar, Vikash;
Singh, Randeep;
Sharma, Arti;
Changotra, Harish;
Parkash, Jyoti

Publication type:

Article

ProgModule: A novel computational framework to identify mutation driver modules for predicting cancer prognosis and immunotherapy response.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06497-0

By:

Li, Xiangmei;
Pan, Bingyue;
Zhao, Xilong;
Su, Yinchun;
Lai, Jiyin;
Li, Siyuan;
He, Yalan;
Wu, Jiashuo;
Han, Junwei

Publication type:

Article

Single-cell multi-omics delineates the dynamics of distinct epigenetic codes coordinating mouse gastrulation.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11619-5

By:

Fu, Mingzhu;
Pang, Long;
Wu, Zhenwei;
Wang, Mei;
Jin, Jin;
Ai, Shanshan;
Li, Xin

Publication type:

Article

Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRAS<sup>G13D</sup> colorectal cancer.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02343-5

By:

Hwang, Soo-Yeon;
Seo, Yoojeong;
Park, Seojeong;
Kim, Seul-Ah;
Moon, Inhye;
Liu, Yi;
Kim, Seojeong;
Pak, Eun Seon;
Jung, Sehyun;
Kim, Hyeyoon;
Jeon, Kyung-Hwa;
Seo, Seung Hee;
Sung, Inyoung;
Lee, Heetak;
Park, So-Yeon;
Na, Younghwa;
Kim, Tae Il;
Kwon, Youngjoo

Publication type:

Article

Optimal transport reveals dynamic gene regulatory networks via gene velocity estimation.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.pcbi.1012476

By:

Zhao, Wenjun;
Larschan, Erica;
Sandstede, Björn;
Singh, Ritambhara

Publication type:

Article

基于生物信息学分析双硫死亡相关基因在代谢相关脂肪性肝病中的作用.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2025, v. 46, n. 2, p. 249, doi. 10.7652/jdyxb202502008

By:

熊永强;
王博;
王纪云;
李韧;
张澍

Publication type:

Article

Key gene screening and diagnostic model establishment for acute type a aortic dissection.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1586880

By:

Pan, Yue;
Yu, Zhiming;
Qian, Xiaoyu;
Zhang, Xuesong;
Xue, Qun;
Xiao, Weizhang

Publication type:

Article

Interpreting roles of mutations associated with the emergence of S. aureus USA300 strains using transcriptional regulatory network reconstruction.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.90668

By:

Poudel, Saugat;
Hyun, Jason;
Ying Hefner;
Monk, Jon;
Nizet, Victor;
Palsson, Bernhard O.

Publication type:

Article

Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1525416

By:

Zhou, Yimin;
Li, Xin;
Wang, Zixiu;
Ng, Liqi;
He, Rong;
Liu, Chaozong;
Liu, Gang;
Fan, Xiao;
Mu, Xiaohong;
Zhou, Yu

Publication type:

Article

Dissecting the role of bHLH transcription factors in the potato spindle tuber viroid (PSTVd)-tomato pathosystem using network approaches.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0318573

By:

Aviña-Padilla, Katia;
Zambada-Moreno, Octavio;
Jimenez-Limas, Marco A.;
Hammond, Rosemarie W.;
Hernández-Rosales, Maribel

Publication type:

Article

Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-02013-z

By:

Ali, Muhammad;
Garcia, Pierre;
Lunkes, Laetitia P.;
Sciortino, Alessia;
Thomas, Melanie H.;
Heurtaux, Tony;
Grzyb, Kamil;
Halder, Rashi;
Skupin, Alexander;
Buée, Luc;
Blum, David;
Buttini, Manuel;
Glaab, Enrico

Publication type:

Article

Integrated transcriptomic and metabolomic analyses reveal regulatory networks governing hub metabolic pathways in Fraxinus hupehensis seeds during germination.

Published in:

Tree Physiology, 2025, v. 45, n. 4, p. 1, doi. 10.1093/treephys/tpaf032

By:

Wei, Yifan;
Deng, Jing;
Tang, Huan;
Xu, Jia;
Zhou, Mingqin;
Ye, Jiabao

Publication type:

Article

Identification of the shared gene signatures and biological mechanism in type 2 diabetes mellitus and hepatocellular carcinoma.

Published in:

Clinical & Experimental Hepatology, 2025, v. 11, n. 1, p. 34, doi. 10.5114/ceh.2025.148439

By:

Lin, Yuxi;
Liao, Jiasheng;
Chong, Yutian

Publication type:

Article

Comprehensive visceral transcriptome profiling of three pig breeds along altitudinal gradients in Yunnan.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05070-0

By:

Huo, Jinlong;
Liu, Zhipeng;
Zhang, Xia;
Li, Changyao;
Xiang, Decai;
Fu, Guowen;
Lin, Wan;
Wu, Lingxiang;
Gong, Shaorong;
Zhao, Jiading;
Wang, Zhen;
Wang, Xiaohong;
Xiao, Zhiping;
Hao, Fanfan;
Ren, Yue;
Sun, Yu H.;
Zhao, Guiying

Publication type:

Article

Evolution and comparison of the expression of TCP genes in the benincaseae and cucurbiteae tribes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99296-y

By:

Wang, Shuoshuo;
Li, Wenli;
Jin, Han

Publication type:

Article

Pilot study using a discrete mathematical approach for topological analysis and ssGSEA of gene expression in autosomal recessive polycystic kidney disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99048-y

By:

Okui, Nobuo;
Hachiya, Tsuyoshi;
Horie, Shigeo

Publication type:

Article

CLEC7A 调节 PD-L1 促进卵巢癌生长的作用及机制研究.

Published in:

Journal of New Medicine, 2025, v. 56, n. 4, p. 361, doi. 10.12464/j.issn.0253-9802.2025-0056

By:

陈瑶;
孙思柏;
许俊;
何杰

Publication type:

Article

Genetic association between gene expression profiles in oligodendrocyte precursor cells and psychiatric disorders.

Published in:

Frontiers in Psychiatry, 2025, p. 1, doi. 10.3389/fpsyt.2025.1566155

By:

Kondo, Reon;
Kimura, Hiroki;
Ikeda, Masashi

Publication type:

Article

A potential XGBoost Diagnostic Score for Staphylococcus aureus bloodstream infection.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574003

By:

Shi, Junhong;
Chen, Lan;
Yuan, Xinru;
Yang, Jinjin;
Xu, Yanlei;
Shen, Li;
Huang, Yu;
Wang, Bingjie;
Yu, Fangyou

Publication type:

Article

Multi-omics identification of a polyamine metabolism related signature for hepatocellular carcinoma and revealing tumor microenvironment characteristics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570378

By:

Yu, Yuexi;
Liu, Huiru;
Liu, Kaipeng;
Zhao, Meiqi;
Zhang, Yiyan;
Jiang, Runci;
Wang, Fengmei

Publication type:

Article