Title: Selectivity of HIF-PH inhibitors: concerns regarding possible off-target effects.
Authors: Nagano, Nobuo
Abstract: Keywords: Renal anemia; Hypoxia-inducible factor-prolyl hydroxylase (HIF-PH); Collagen prolyl 4-hydroxylase (CP4H); HIF-PH inhibitor; Selectivity EN Renal anemia Hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) Collagen prolyl 4-hydroxylase (CP4H) HIF-PH inhibitor Selectivity 1047 1048 2 08/13/21 20210901 NES 210901 I To the Editor i The clinical application of erythropoietin (EPO) brought about a paradigm shift in the treatment of renal anemia. Renal anemia, Hypoxia-inducible factor-prolyl hydroxylase (HIF-PH), Collagen prolyl 4-hydroxylase (CP4H), HIF-PH inhibitor, Selectivity.
Subjects: LYSYL oxidase; OXYGENASES; SMALL molecules; HYPOXIA-inducible factors
Publication: Clinical & Experimental Nephrology, 2021, Vol 25, Issue 9, p1047
ISSN: 1342-1751
Publication type: Academic Journal
DOI: 10.1007/s10157-021-02070-3

Selectivity of HIF-PH inhibitors: concerns regarding possible off-target effects.

Nagano, Nobuo