Blue rubber bleb nevus syndrome with late onset of central nervous system symptomatic involvement.

Tomelleri, Giampaolo; Cappellari, Manuel; Di Matteo, Alessandro; Zanoni, Tiziano; Colato, Chiara; Bovi, Paolo; Moretto, Giuseppe

Blue rubber bleb nevus syndrome is a rare vascular disorder characterized by cavernous angiomas of skin and other organs including the gastrointestinal tract. The central nervous system involvement is seldom reported, and neurological symptoms at onset in adulthood are extremely rare. Here, we describe a case of 82-year-old patient presenting multiple skin haemangiomas for some years, who was admitted for a brain hemorrhage. The MRI demonstrated the presence of multiple cavernous angiomas within the cerebral tissue.

CENTRAL nervous system; BLISTERS; BASAL cell nevus syndrome; GASTROINTESTINAL system; CEREBRAL hemorrhage

Neurological Sciences, 2010, Vol 31, Issue 4, p501

1590-1874

Academic Journal

10.1007/s10072-010-0250-4