Works matching DE "LAPATINIB"

Results: 283

EGFR blocker lapatinib inhibits the synthesis of matrix metalloproteinases from synovial fibroblasts.

Published in:

Turkish Journal of Medical Sciences, 2022, v. 52, n. 4, p. 1355, doi. 10.55730/1300-0144.5442

By:

YALÇIN KEHRİBAR, Demet;
EMMUNGİL, Hakan;
BAŞAK TÜRKMEN, Neşe;
ÇİFTÇİ, Osman;
SALVA, Emine;
ÖZGEN, Metin

Publication type:

Article

QBD-Powered Design and Optimization of Nanostructured Lipid Carriers Loaded with BCS class IV Anticancer Drug.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2024, v. 58, p. S828, doi. 10.5530/ijper.58.3s.84

By:

Haritha, Pamujula Naga;
Janakiraman, Kunchithapatham;
Madhav, Katla Venu;
Kumar Chaitanya, Padavala Sunil

Publication type:

Article

CD36: a key mediator of resistance to HER2 inhibitors in breast cancer.

Published in:

2020

By:

Feng, William W.;
Bang, Scott;
Kurokawa, Manabu

Publication type:

Opinion

EGFR inhibitors erlotinib and lapatinib ameliorate epidermal blistering in pemphigus vulgaris in a non-linear, V-shaped relationship.

Published in:

Experimental Dermatology, 2014, v. 23, n. 1, p. 33, doi. 10.1111/exd.12290

By:

Sayar, Beyza S.;
Rüegg, Simon;
Schmidt, Enno;
Sibilia, Maria;
Siffert, Myriam;
Suter, Maja M.;
Galichet, Arnaud;
Müller, Eliane J.

Publication type:

Article

Physicochemical Characterization and Cyclodextrin Complexation of the Anticancer Drug Lapatinib.

Published in:

Journal of Chemistry, 2017, p. 1, doi. 10.1155/2017/4537632

By:

Tóth, Gergő;
Jánoska, Ádám;
Völgyi, Gergely;
Szabó, Zoltán-István;
Orgován, Gábor;
Mirzahosseini, Arash;
Noszál, Béla

Publication type:

Article

Amino acid modified OCMC-g-Suc-β-CD nanohydrogels carrying lapatinib and ginsenoside Rg1 exhibit high anticancer activity in a zebrafish model.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1149191

By:

Li Cui;
Xiaolan Liu;
Rongjun Yan;
Qixu Chen;
Lizhen Wang;
Nawaz, Shah;
Dawei Qin;
Daijie Wang

Publication type:

Article

BioPATH: A Biomarker Study in Asian Patients with HER2+ Advanced Breast Cancer Treated with Lapatinib and Other Anti-HER2 Therapy.

Published in:

Cancer Research & Treatment, 2019, v. 51, n. 4, p. 1527, doi. 10.4143/crt.2018.598

By:

Sung-Bae Kim;
In-Gu Do;
Janice Tsang;
Tae-You Kim;
Yoon-Sim Yap;
Cornelio, Gerardo;
Gyungyub Gong;
Soonmyung Paik;
Suee Lee;
Ting-Ying Ng;
Sarah Park;
Ho-Suk Oh;
Joanne Chiu;
Joohyuk Sohn;
Moonhee Lee;
Young-Jin Choi;
Eun Mi Lee;
Kyong-Hwa Park;
Nathaniel, Christos;
Jungsil Ro

Publication type:

Article

Cisplatin, Gemcitabine, and Lapatinib as Neoadjuvant Therapy for Muscle-Invasive Bladder Cancer.

Published in:

Cancer Research & Treatment, 2016, v. 48, n. 3, p. 1084, doi. 10.4143/crt.2015.405

By:

Narayan, Vivek;
Mamtani, Ronac;
Keefe, Stephen;
Guzzo, Thomas;
Malkowicz, S. Bruce;
Vaughn, David J.

Publication type:

Article

Effective Treatment of Solitary Pituitary Metastasis with Panhypopituitarism in HER2-Positive Breast Cancer by Lapatinib.

Published in:

2016

By:

Youngmok Park;
Hyemin Kim;
Eui-Hyun Kim;
Chang-Ok Suh;
Soohyeon Lee

Publication type:

Case Study

Lapatinib antitumor effect is associated with PI3K and MAPK pathway: An analysis in human and canine prostate cancer cells.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0297043

By:

Fonseca-Alves, Carlos Eduardo;
Leis-Filho, Antonio Fernando;
Lacerda, Zara Alves;
de Faria Lainetti, Patricia;
Amorim, Renee Laufer;
Rogatto, Silvia Regina

Publication type:

Article

Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: A pilot study

Published in:

Molecular Oncology, 2012, v. 6, n. 4, p. 437, doi. 10.1016/j.molonc.2012.05.003

By:

Tenori, Leonardo;
Oakman, Catherine;
Claudino, Wederson M.;
Bernini, Patrizia;
Cappadona, Silvia;
Nepi, Stefano;
Biganzoli, Laura;
Arbushites, Michael C.;
Luchinat, Claudio;
Bertini, Ivano;
Di Leo, Angelo

Publication type:

Article

Molecular recognition of tak-285 and lapatinib by inactive, active, and middle active-inactive HER2.

Published in:

Journal of Molecular Modeling, 2021, v. 27, n. 4, p. 1, doi. 10.1007/s00894-021-04720-5

By:

Martiniano, Bello

Publication type:

Article

Theoretical study on the mechanism of N- and α-carbon oxidation of lapatinib catalyzed by cytochrome P450 monooxygenase.

Published in:

Journal of Molecular Modeling, 2019, v. 25, n. 8, p. N.PAG, doi. 10.1007/s00894-019-4125-1

By:

Huang, Hong;
Bai, Xue;
Yang, Lijun

Publication type:

Article

Phase I clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion.

Published in:: Journal of Translational Medicine, 2012, v. 10, n. 1, p. 28, doi. 10.1186/1479-5876-10-28
Publication type:: Article

Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors.

Published in:

Cell Research, 2014, v. 24, n. 5, p. 542, doi. 10.1038/cr.2014.37

By:

Sahin, Ozgur;
Wang, Qingfei;
Brady, Samuel W;
Ellis, Kenneth;
Wang, Hai;
Chang, Chia-Chi;
Zhang, Qingling;
Priya, Preety;
Zhu, Rui;
Wong, Stephen T;
Landis, Melissa D;
Muller, William J;
Esteva, Francisco J;
Chang, Jenny;
Yu, Dihua

Publication type:

Article

A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer.

Published in:

2021

By:

Ning, Gang;
Zhu, Qihui;
Kang, Wonyoung;
Lee, Hamin;
Maher, Leigh;
Suh, Yun-Suhk;
Michaud, Michael;
Silva, Mayerlin;
Kwon, Jee Young;
Zhang, Chengsheng;
Lee, Charles

Publication type:

journal article

Mathematical modeling identifies optimum lapatinib dosing schedules for the treatment of glioblastoma patients.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 1, p. 1, doi. 10.1371/journal.pcbi.1005924

By:

Stein, Shayna;
Zhao, Rui;
Haeno, Hiroshi;
Vivanco, Igor;
Michor, Franziska

Publication type:

Article

Cost-effectiveness of lapatinib plus capecitabine in women with HER2+ metastatic breast cancer who have received prior therapy with trastuzumab.

Published in:

European Journal of Health Economics, 2012, v. 13, n. 5, p. 589, doi. 10.1007/s10198-011-0323-1

By:

Delea, Thomas;
Tappenden, Paul;
Sofrygin, Oleg;
Browning, Dominy;
Amonkar, Mayur;
Karnon, Jon;
Walker, Mel;
Cameron, David

Publication type:

Article

Treatment - Metastatic and Advanced Disease.

Published in:: Current Medical Literature: Breast Cancer, 2012, v. 24, n. 3, p. 106
Publication type:: Article

The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma.

Published in:

Journal of Neuro-Oncology, 2017, v. 135, n. 1, p. 47, doi. 10.1007/s11060-017-2567-9

By:

Paldor, Iddo;
Abbadi, Sara;
Bonne, Nicolas;
Ye, Xiaobu;
Rodriguez, Fausto;
Rowshanshad, David;
Itzoe, MariaLisa;
Vigilar, Veronica;
Giovannini, Marco;
Brem, Henry;
Blakeley, Jaishri;
Tyler, Betty

Publication type:

Article

Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.

Published in:

Journal of Neuro-Oncology, 2017, v. 134, n. 2, p. 357, doi. 10.1007/s11060-017-2533-6

By:

Yu, Andrew;
Faiq, Nadia;
Green, Stacey;
Lai, Albert;
Green, Richard;
Hu, Jethro;
Cloughesy, Timothy;
Mellinghoff, Ingo;
Nghiemphu, P.

Publication type:

Article

Lapatinib with whole brain radiotherapy in patients with brain metastases from breast and non-small cell lung cancer: a phase II study of the Hellenic Cooperative Oncology Group (HeCOG).

Published in:

Journal of Neuro-Oncology, 2017, v. 134, n. 2, p. 443, doi. 10.1007/s11060-017-2548-z

By:

Christodoulou, Christos;
Kalogera-Fountzila, Anna;
Karavasilis, Vasilios;
Kouvatseas, George;
Papandreou, Christos;
Samantas, Epaminontas;
Varaki, Kalliopi;
Papadopoulos, Georgios;
Bobos, Mattheos;
Rallis, Grigorios;
Razis, Evangelia;
Goudopoulou, Athina;
Kalogeras, Konstantine;
Syrigos, Konstantinos;
Fountzilas, George

Publication type:

Article

An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).

Published in:

Journal of Neuro-Oncology, 2015, v. 123, n. 1, p. 85, doi. 10.1007/s11060-015-1764-7

By:

DeWire, Mariko;
Fouladi, Maryam;
Turner, David;
Wetmore, Cynthia;
Hawkins, Cynthia;
Jacobs, Carmen;
Yuan, Ying;
Liu, Diane;
Goldman, Stewart;
Fisher, Paul;
Rytting, Michael;
Bouffet, Eric;
Khakoo, Yasmin;
Hwang, Eugene;
Foreman, Nicholas;
Stewart, Clinton;
Gilbert, Mark;
Gilbertson, Richard;
Gajjar, Amar

Publication type:

Article

Activation of ErbB2- ErbB3 signaling pathway supports potential therapeutic activity of ErbB inhibitors in AT/RT.

Published in:

2014

By:

Sredni, Simone;
Patel, Kashyap;
Costa, Felipe;
de Fátima Bonaldo, Maria;
Tomita, Tadanori

Publication type:

Letter

A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study.

Published in:

Journal of Neuro-Oncology, 2013, v. 114, n. 2, p. 173, doi. 10.1007/s11060-013-1166-7

By:

Fouladi, Maryam;
Stewart, Clinton;
Blaney, Susan;
Onar-Thomas, Arzu;
Schaiquevich, Paula;
Packer, Roger;
Goldman, Stewart;
Geyer, J.;
Gajjar, Amar;
Kun, Larry;
Boyett, James;
Gilbertson, Richard

Publication type:

Article

Impacts of HER2-overexpression and molecular targeting therapy on the efficacy of stereotactic radiosurgery for brain metastases from breast cancer.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 2, p. 199, doi. 10.1007/s11060-013-1046-1

By:

Yomo, Shoji;
Hayashi, Motohiro;
Cho, Narisumi

Publication type:

Article

Exploring the Potential of Lapatinib, Fulvestrant, and Paclitaxel Conjugated with Glycidylated PAMAM G4 Dendrimers for Cancer and Parasite Treatment.

Published in:

Molecules, 2023, v. 28, n. 17, p. 6334, doi. 10.3390/molecules28176334

By:

Uram, Łukasz;
Wróbel, Konrad;
Walczak, Małgorzata;
Szymaszek, Żaneta;
Twardowska, Magdalena;
Wołowiec, Stanisław

Publication type:

Article

Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1571, doi. 10.3390/molecules25071571

By:

de Sousa, Ana Carolina C.;
Maepa, Keletso;
Combrinck, Jill M.;
Egan, Timothy J.;
Zorc, Branka;
Rajić, Zrinka

Publication type:

Article

Synergistic Antitumor Effects on Drug-Resistant Breast Cancer of Paclitaxel/Lapatinib Composite Nanocrystals.

Published in:

Molecules, 2020, v. 25, n. 3, p. 604, doi. 10.3390/molecules25030604

By:

Wang, Jun;
Lv, Feng-Mei;
Wang, Dong-Li;
Du, Jian-Liang;
Guo, Hai-Yan;
Chen, Hai-Ni;
Zhao, Shou-Jin;
Liu, Zhe-Peng;
Liu, Yu;
Panzavolta, Silvia;
Dolci, Luisa Stella

Publication type:

Article

HER2-positive breast cancer - Available anti-HER2 therapies and new agents under investigation.

Published in:

Journal of Pre-Clinical & Clinical Research, 2020, v. 14, n. 2, p. 44, doi. 10.26444/jpccr/122068

By:

Zielińska, Martyna;
Zarankiewicz, Natalia;
Kosz, Katarzyna;
Kuchnicka, Aleksandra;
Ciseł, Bogumiła

Publication type:

Article

Cytotoxic Effects of the Dual ErbB Tyrosine Kinase Inhibitor, Lapatinib, on Walker 256 Rat Breast Tumour and IEC-6 Rat Normal Small Intestinal Cell Lines.

Published in:

Biomedicines, 2020, v. 8, n. 1, p. 2, doi. 10.3390/biomedicines8010002

By:

Wan Mohamad Zain, Wan Nor I′zzah;
Bowen, Joanne;
Bateman, Emma;
Keefe, Dorothy

Publication type:

Article

Anti-tumour effects of lapatinib on HER2-positive canine prostatic carcinoma cell lines.

Published in:

Open Veterinary Journal, 2024, v. 14, n. 5, p. 1259, doi. 10.5455/OVJ.2024.v14.i5.21

By:

Kenjiro Kaji;
Tomoki Motegi;
Tomohiro Yonezawa;
Yasuyuki Momoi;
Shingo Maeda

Publication type:

Article

MicroRNA in combination with HER2-targeting drugs reduces breast cancer cell viability in vitro.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90385-2

By:

Normann, Lisa Svartdal;
Aure, Miriam Ragle;
Leivonen, Suvi-Katri;
Haugen, Mads Haugland;
Hongisto, Vesa;
Kristensen, Vessela N.;
Mælandsmo, Gunhild Mari;
Sahlberg, Kristine Kleivi

Publication type:

Article

Clinical data mining reveals analgesic effects of lapatinib in cancer patients.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82318-w

By:

Zhou, Shuo;
Zheng, Fang;
Zhan, Chang-Guo

Publication type:

Article

DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67283-0

By:

Zhou, Shuo;
Zhou, Ziyuan;
Ding, Kai;
Yuan, Yaxia;
Loftin, Charles;
Zheng, Fang;
Zhan, Chang-Guo

Publication type:

Article

Economic evaluation of third-line neratinib plus capecitabine versus lapatinib plus capecitabine with HER2+ metastatic breast cancer.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1221969

By:

Lanqi Ren;
Ning Ren;
Yu Zheng;
Yibei Yang;
Qiaoping Xu

Publication type:

Article

LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib.

Published in:

Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00025

By:

Xiang, Zhen;
Song, Shuzheng;
Zhu, Zhenggang;
Sun, Wenhong;
Gifts, Jaron E.;
Sun, Sam;
Li, Qiushi Shauna;
Yu, Yingyan;
Li, Keqin Kathy

Publication type:

Article

Assay of lapatinib in murine models of cigarette smoke carcinogenesis.

Published in:

Carcinogenesis, 2014, v. 35, n. 10, p. 2300, doi. 10.1093/carcin/bgu154

By:

Balansky, Roumen;
Izzotti, Alberto;
D’Agostini, Francesco;
Longobardi, Mariagrazia;
Micale, Rosanna T.;
La Maestra, Sebastiano;
Camoirano, Anna;
Ganchev, Gancho;
Iltcheva, Marietta;
Steele, Vernon E.;
De Flora, Silvio

Publication type:

Article

Re-analysis of data on use of breast cancer medicine Tyverb following treatment with trastuzumab.

Published in:

Medical Writing, 2019, v. 28, n. 3, p. 74

By:

Alahari, Anuradha

Publication type:

Article

Gene isoforms as expression-based biomarkers predictive of drug response in vitro.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01153-8

By:

Safikhani, Zhaleh;
Smirnov, Petr;
Thu, Kelsie L.;
Silvester, Jennifer;
El-Hachem, Nehme;
Quevedo, Rene;
Lupien, Mathieu;
Mak, Tak W.;
Cescon, David;
Haibe-Kains, Benjamin

Publication type:

Article

Determination of Lapatinib in Bulk and Tablet Dosage Form using Ultraviolet Spectrophotometric and RP-HPLC Analytical Methods.

Published in:

International Journal of Pharmaceutical Investigation, 2021, v. 11, n. 2, p. 208, doi. 10.5530/ijpi.2021.2.37

By:

Mondal, Sumanta;
Biswal, Sabyasachi;
Acharya, Trayambica;
Mondal, Prasenjit;
Bhar, Kausik

Publication type:

Article

The human epidermal growth factor receptor 2 (HER2).

Published in:

Clinical Chemistry & Laboratory Medicine, 2012, v. 50, n. 1, p. 23, doi. 10.1515/cclm.2011.707

By:

Tafe, Laura J.;
Tsongalis, Gregory J.

Publication type:

Article

Phase III Trial of Lapatinib.

Published in:

Pharmaceutical Medicine, 2012, v. 26, n. 5, p. 321, doi. 10.1007/BF03262377

By:

Sweetlove, Mel

Publication type:

Article

Development and Validation of a Rapid RP-HPLC-DAD Analysis Method for the Simultaneous Quantitation of Paclitaxel and Lapatinib in a Polymeric Micelle Formulation.

Published in:

Scientia Pharmaceutica, 2016, v. 84, n. 2, p. 333, doi. 10.3797/scipharm.1507-03

By:

SAADAT, Ebrahim;
RAVAR, Fatemeh;
DEHGHANKELISHADI, Pouya;
DORKOOSH, Farid A.

Publication type:

Article

Neuregulin 1 Reduces Motoneuron Cell Death and Promotes Neurite Growth in an in Vitro Model of Motoneuron Degeneration.

Published in:

Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2017.00431

By:

Mòdol-Caballero, Guillem;
Santos, Daniel;
Navarro, Xavier;
Herrando-Grabulosa, Mireia

Publication type:

Article

Long-term Survival after Lapatinib Rechallenge in Isolated Brain Metastasis of HER2-positive Breast Cancer.

Published in:

2015

By:

Karagöz, Bülent;
Özgün, Alpaslan;
Emirzeoğlu, Levent;
Tunçel, Tolga;
Çelik, Serkan;
Bilgi, Oğuz;
Kara, Kemal

Publication type:

Case Study

Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling.

Published in:

BMC Systems Biology, 2015, v. 9, n. 1, p. 1, doi. 10.1186/s12918-014-0135-x

By:

AKM, AKM;
Lawen, Alfons;
Keith, Jonathan

Publication type:

Article

Phase I study of weekly paclitaxel in combination with pazopanib and lapatinib in advanced solid malignancies.

Published in:

British Journal of Cancer, 2014, v. 110, n. 11, p. 2647, doi. 10.1038/bjc.2014.233

By:

Tan, A R;
Dowlati, A;
Stein, M N;
Jones, S F;
Infante, J R;
Bendell, J;
Kane, M P;
Levinson, K T;
Suttle, A B;
Burris III, H A

Publication type:

Article

Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial.

Published in:

British Journal of Cancer, 2014, v. 110, n. 5, p. 1139, doi. 10.1038/bjc.2013.831

By:

Alba, E;
Albanell, J;
de la Haba, J;
Barnadas, A;
Calvo, L;
Sánchez-Rovira, P;
Ramos, M;
Rojo, F;
Burgués, O;
Carrasco, E;
Caballero, R;
Porras, I;
Tibau, A;
Cámara, M C;
Lluch, A

Publication type:

Article

BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib.

Published in:

British Journal of Cancer, 2012, v. 107, n. 6, p. 947, doi. 10.1038/bjc.2012.351

By:

Godinho, M F E;
Wulfkuhle, J D;
Look, M P;
Sieuwerts, A M;
Sleijfer, S;
Foekens, J A;
Petricoin, E F;
Dorssers, L C J;
van Agthoven, T

Publication type:

Article