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- Title
Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort.
- Authors
Macul Ferreira de Barros, Pedro; do Rosário, Maria Conceição; Szejko, Natalia; Polga, Natália; Requena, Guaraci de Lima; Ravagnani, Beatriz; Fatori, Daniel; Batistuzzo, Marcelo Camargo; Hoexter, Marcelo Queiroz; Rohde, Luis Augusto; Polanczyk, Guilherme Vanoni; Leckman, James Frederick; Miguel, Eurípedes Constantino; de Alvarenga, Pedro Gomes
- Abstract
Environmental factors are at least as important as genetic factors for the development of obsessive–compulsive symptoms (OCS), but the identification of such factors remain a research priority. Our study aimed to investigate the association between a broad scope of potential risk factors and OCS in a large community cohort of children and adolescents. We evaluated 1877 participants and their caregivers at baseline and after 3 years to assess various demographic, prenatal, perinatal, childhood adversity, and psychopathological factors. Mean age at baseline was 10.2 years (SD 1.9) and mean age at follow-up was 13.4 years (SD 1.9). Reports of OCS at baseline and follow-up were analyzed using latent variable models. At preliminary regression analysis, 15 parameters were significantly associated with higher OCS scores at follow-up. At subsequent regression analysis, we found that eight of these parameters remained significantly associated with higher follow-up OCS scores while being controlled by each other and by baseline OCS scores. The significant predictors of follow-up OCS were: lower socioeconomic status (p = 0.033); lower intelligence quotient (p = 0.013); lower age (p < 0.001); higher maternal stress level during pregnancy (p = 0.028); absence of breastfeeding (p = 0.017); parental baseline OCS (p = 0.038); youth baseline anxiety disorder (p = 0.023); and youth baseline OCS scores (p < 0.001). These findings may better inform clinicians and policymakers engaged in the mental health assessment and prevention in children and adolescents.
- Subjects
AGE distribution; PSYCHOLOGY of caregivers; PATIENT aftercare; INTELLECT; LONGITUDINAL method; OBSESSIVE-compulsive disorder; REGRESSION analysis; RISK assessment; SOCIOECONOMIC factors; DESCRIPTIVE statistics; ADOLESCENCE; CHILDREN
- Publication
European Child & Adolescent Psychiatry, 2021, Vol 30, Issue 1, p89
- ISSN
1018-8827
- Publication type
Academic Journal
- DOI
10.1007/s00787-020-01495-7