Works matching DE "TUMOR microenvironment"

Results: 5000

Integrating Mendelian randomization and multi-transcriptomic analyses to unveil the genetic association risk of regulatory T cell-mediated free cholesterol and gastric cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02739-1

By:

Peng, Fanyu;
Liu, Haitao;
Guo, Yesong;
Wen, Jing;
Ge, Yizhi;
Luo, Yanhong

Publication type:

Article

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101369

By:

Bhattacharya, Arkajyoti;
Stutvoet, Thijs S.;
Perla, Mirela;
Loipfinger, Stefan;
Jalving, Mathilde;
Reyners, Anna K. L.;
Vermeer, Paola D.;
Drapkin, Ronny;
de Bruyn, Marco;
de Vries, Elisabeth G. E.;
de Jong, Steven;
Fehrmann, Rudolf S. N.

Publication type:

Article

Cancer‐associated fibroblast heterogeneity in chordoma†.

Published in:

Journal of Pathology, 2025, v. 266, n. 1, p. 5, doi. 10.1002/path.6420

By:

Henry, Jack C;
Cameron, Angus J M

Publication type:

Article

Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms.

Published in:

Journal of Pathology, 2025, v. 266, n. 1, p. 40, doi. 10.1002/path.6402

By:

Jamouss, Kevin T;
Damanakis, Alexander Ioannis;
Cornwell, Abigail C;
Jongepier, Martine;
Trujillo, Maria A;
Pflüger, Michael Johannes;
Kawalerski, Ryan;
Maalouf, Alexandre;
Hirose, Katsuya;
Datta, Shalini;
Sipes, Abigail;
Pedro, Brian A;
Gudmundsson, Emma;
Assarzadegan, Naziheh;
Engle, Logan;
Scharpf, Robert B;
Kawamoto, Satomi;
Thompson, Elizabeth D;
Wood, Laura D

Publication type:

Article

Circulating miR-485-3p as a biomarker for VEGF-associated therapeutic response to atezolizumab plus bevacizumab in hepatocellular carcinoma.

Published in:

Journal of Gastroenterology, 2025, v. 60, n. 6, p. 770, doi. 10.1007/s00535-025-02239-7

By:

Oura, Kyoko;
Morishita, Asahiro;
Yano, Rie;
Manabe, Takushi;
Takuma, Kei;
Nakahara, Mai;
Tadokoro, Tomoko;
Fujita, Koji;
Mimura, Shima;
Tani, Joji;
Tatsuta, Miwa;
Himoto, Takashi;
Masaki, Tsutomu;
Kobara, Hideki

Publication type:

Article

Prognosis and tumor microenvironment in pseudohypoxic pheochromocytoma/paraganglioma.

Published in:

Virchows Archiv: European Journal of Pathology, 2025, v. 486, n. 5, p. 983, doi. 10.1007/s00428-024-04009-x

By:

Ohmoto, Akihiro;
Shigematsu, Yasuyuki;
Saito, Rumiko;
Dobashi, Akito;
Fujiwara, Yu;
Togashi, Yuki;
Yonese, Junji;
Inamura, Kentaro;
Takahashi, Shunji

Publication type:

Article

Digital spatial profiling for pathologists.

Published in:

Virchows Archiv: European Journal of Pathology, 2025, v. 486, n. 5, p. 971, doi. 10.1007/s00428-024-03955-w

By:

Donati, Benedetta;
Manzotti, Gloria;
Torricelli, Federica;
Ascione, Cristian;
Valli, Riccardo;
Santandrea, Giacomo;
Ragazzi, Moira;
Zanetti, Eleonora;
Ciarrocchi, Alessia;
Piana, Simonetta

Publication type:

Article

HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)- trastuzumab.

Published in:

Pathology & Oncology Research, 2025, p. 1, doi. 10.3389/pore.2025.1611999

By:

Ngô, Toàn Minh;
Vágner, Adrienn;
Nagy, Gábor;
Ország, Gábor;
Nagy, Tamás;
Szoboszlai, Zoltán;
Csikos, Csaba;
Váradi, Balázs;
Trencsényi, György;
Tircsó, Gyula;
Garai, Ildikó

Publication type:

Article

Olaparib reverses prostate cancer resistance to Rapamycin by promoting macrophage polarization towards the M1 phenotype.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 6, p. 3907, doi. 10.1007/s11010-025-05231-0

By:

Ye, Kai;
Shi, Gang;
Xu, Jian;
Qiao, Kunyan;
Dai, Qinghai;
Huo, Zhixiao;
Cao, Yu;
Liu, Wei;
Hu, Yue;
Yan, Lihua;
Zhu, Yu;
Li, Ping;
Su, Rui;
Xu, Liang;
Mi, Yuqiang

Publication type:

Article

Tumor microenvironment noise-induced polarization: the main challenge in macrophages' immunotherapy for cancer.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 6, p. 3735, doi. 10.1007/s11010-025-05205-2

By:

Sierra, Jesus;
de León, Ugo Avila-Ponce;
Padilla-Longoria, Pablo

Publication type:

Article

SELP can affect the immune microenvironment of gastric cancer and is associated with poor prognosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02629-6

By:

Wu, Yue;
Liu, Jingyu;
Yin, Tong;
Li, Xiaoxiao;
Liu, Xian;
Peng, Xiaobo;
Zhan, Xianbao

Publication type:

Article

Metabolic reprogramming and immune microenvironment profiling in clear cell renal cell carcinoma: implications for prognosis, targeted therapy, and drug resistance.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02401-w

By:

Zheng, Xiao;
Liu, Yongqiang;
Yang, Zixin;
Tian, Yanhua

Publication type:

Article

Reactive oxygen species responsive nanomotors for gene edited metabolic disruption and immunotherapy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59590-9

By:

Liu, Zhiyong;
Luan, Xiaowei;
Lu, Qianglan;
Qin, Shurong;
Zeng, Fei;
Li, Zhi;
He, Bangshun;
Song, Yujun

Publication type:

Article

Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions.

Published in:

Aging & Disease, 2025, v. 16, n. 2, p. 645, doi. 10.14336/AD.2024.0327

By:

Dengxiong Li;
Qingxin Yu;
Ruicheng Wu;
Zhouting Tuo;
Weizhen Zhu;
Jie Wang;
Fanglin Shao;
Luxia Ye;
Xing Ye;
Koo Han Yoo;
Mang Ke;
Yubo Yang;
Wuran Wei;
Dechao Feng

Publication type:

Article

S-adenosylmethionine metabolism shapes CD8+ T cell functions in colorectal cancer.

Published in:

Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00394-2

By:

Yang, Xiaohua;
Kou, Tianzhang;
Wang, Hongmiao;
Zhu, Ji;
Zhu, Zheng-Jiang;
Cai, Yuping

Publication type:

Article

The progress and prospects of targeting the adenosine pathway in cancer immunotherapy.

Published in:

Biomarker Research, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40364-025-00784-0

By:

Yang, Yuying;
Zhu, Lin;
Xu, Yantao;
Liang, Long;
Liu, Li;
Chen, Xiang;
Li, Hui;
Liu, Hong

Publication type:

Article

To verify the biological characteristics of disulfidptosis associated gene ADORA2B in esophageal cancer.

Published in:

BMC Gastroenterology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12876-025-03768-4

By:

Cui, Yixiao;
Deng, Yuhan;
Wu, Zhenhua;
Sun, Xiaohong

Publication type:

Article

Overcoming multifaceted challenges in cancer treatment: Targeting signal transduction pathways and tumor microenvironment for enhanced therapeutic efficacy.

Published in:

Journal of Applied Pharmaceutical Science, 2025, v. 15, n. 5, p. 040, doi. 10.7324/JAPS.2025.204012

By:

Ansari, Abdul Majeed;
Sharma, Naresh Kumar;
Tripathi, Kashinath;
Bhardwaj, Gautam;
Chauhan, Ritu;
Tonk, Rajiv Kumar;
Shahwan, Moyad;
Tuli, Hardeep Singh;
Chauhan, Abhishek

Publication type:

Article

Reactive oxygen species responsive nanomotors for gene edited metabolic disruption and immunotherapy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59590-9

By:

Liu, Zhiyong;
Luan, Xiaowei;
Lu, Qianglan;
Qin, Shurong;
Zeng, Fei;
Li, Zhi;
He, Bangshun;
Song, Yujun

Publication type:

Article

Matrix Remodeling Associated Genes (MXRAs): structural diversity, functional significance, and therapeutic potential in tumor microenvironments.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02728-4

By:

Zeng, Chao;
Lv, Xiao;
Wang, Feng;
Huang, Yaomin;
Ren, Yanxian;
Zhang, Hengwei

Publication type:

Article

Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02673-2

By:

Xu, Shuang;
Luo, Yang;
He, Yuzhu;
Chen, Yuxiang;
Qin, Fengfeng;
Hu, Wenjian

Publication type:

Article

Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02421-6

By:

Tao, Siyu;
Yang, Yunhao

Publication type:

Article

Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02506-2

By:

Zhang, Xiaoyan;
Guan, Zuojia;
Xu, Zhan

Publication type:

Article

Plant polysaccharides influence tumor development based on epigenetics: a review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588857

By:

Li, Cong;
Hu, Yuao;
Yang, Hua

Publication type:

Article

Pan-cancer analysis of phagocytosis regulators in female-specific cancers: a focus on HMGB2.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1565924

By:

Lu, Xiaoqin;
Ren, Dan;
Zhao, Panpan;
Li, Yanfang;
Wang, Zhenhui;
Zhang, Jingyan

Publication type:

Article

MicroRNA-486: a dual-function biomarker for diagnosis and tumor immune microenvironment characterization in non-small cell lung cancer.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02158-9

By:

Yu, Jun;
Shen, Yi;
Xu, Yao;
Feng, Zhengyang;
Shen, Yuntian;
Zhu, Yaqun;
Huan, Jian;
Peng, Qiliang

Publication type:

Article

Polyaniline-coated iron oxide nanoparticles reprogram macrophages and modulate the tumor microenvironment to inhibit breast cancer progression and metastasis.

Published in:

Cancer Nanotechnology (1868-6958), 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00323-4

By:

Nascimento, Camila Sales;
Carvalho, Júlia Gallo;
Tavares, Naiara Clemente;
Lage, Anna Carolina Pinheiro;
Pascoal-Xavier, Marcelo Antônio;
Melo, Celso Pinto de;
Alves, Érica Alessandra Rocha;
Calzavara-Silva, Carlos Eduardo

Publication type:

Article

Cluster Analysis of VERDICT MRI for Cancer Tissue Characterization in Neuroendocrine Tumors.

Published in:

NMR in Biomedicine, 2025, v. 38, n. 6, p. 1, doi. 10.1002/nbm.70050

By:

Lundholm, Lukas;
Montelius, Mikael;
Jalnefjord, Oscar;
Schoultz, Elin;
Forssell‐Aronsson, Eva;
Ljungberg, Maria

Publication type:

Article

On a mathematical model with a free boundary for the dynamics of the Tumor-Immune system interaction.

Published in:

Uzbek Mathematical Journal, 2025, v. 69, n. 1, p. 163, doi. 10.29229/uzmj.2025-1-16

By:

J. O., Takhirov;
B. B., Anvarjonov

Publication type:

Article

USP2 inhibition unleashes CD47-restrained phagocytosis and enhances anti-tumor immunity.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59621-5

By:

Dai, Panpan;
Sun, Yishuang;
Huang, Zhengrong;
Liu, Yu-Tong;
Gao, Minling;
Liu, Hai-Ming;
Shi, Jie;
He, Chuan;
Xiang, Bolin;
Yao, Yingmeng;
Yu, Haisheng;
Xu, Gaoshan;
Kong, Lijun;
Xiao, Xiangling;
Wang, Xiyong;
Zhang, Xue;
Xiong, Wenjun;
Hu, Jing;
Lin, Dandan;
Zhong, Bo

Publication type:

Article

SLAMF receptors: key regulators of tumor progression and emerging targets for cancer immunotherapy.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02308-8

By:

Li, Jia;
Fan, Tao;
Wang, Di;
Xiao, Chu;
Deng, Ziqin;
Cai, Wenpeng;
Ji, Yu;
Li, Chunxiang;
He, Jie

Publication type:

Article

Evaluation of Serum Level of Chemokine (C‐C Motif) Ligand 2 (CCL2) in Canine Urothelial Carcinomas, Mast Cell Tumours, and Insulinomas, and Its Correlation With Circulating Monocytes.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 300, doi. 10.1111/vco.13056

By:

Shimizu, Naomi;
Hamaide, Annick;
Noël, Stéphanie;
Clercx, Cécile;
Teske, Erik

Publication type:

Article

PD‐L1, PD‐1, and CTLA‐4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 141, doi. 10.1111/vco.13039

By:

Foiani, Greta;
Melchiotti, Erica;
Capello, Katia;
Porcellato, Ilaria;
Brachelente, Chiara;
Iussich, Selina;
Giacobino, Davide;
Morello, Emanuela;
Martano, Marina;
Buracco, Paolo;
Vascellari, Marta

Publication type:

Article

Machine learning and single-cell analysis uncover distinctive characteristics of CD300LG within the TNBC immune microenvironment: experimental validation.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01690-3

By:

Zhu, Baoxi;
Wan, Hong;
Ling, Zichen;
Jiang, Han;
Pei, Jing

Publication type:

Article

Targeting LAT1 with JPH203 to reduce TNBC proliferation and reshape suppressive immune microenvironment by blocking essential amino acid uptake.

Published in:

Amino Acids, 2025, v. 57, n. 1, p. 1, doi. 10.1007/s00726-025-03456-3

By:

Zhao, Yajie;
Pu, Chunrui;
Liu, Kangdong;
Liu, Zhenzhen

Publication type:

Article

A Novel Nanodrug Suppresses Lung Cancer Growth and Metastasis in C57BL/6 Mouse Model by Altering CD8+ Cell Infiltration and Oxidative Stress.

Published in:

Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 3, p. 313, doi. 10.18502/ijaai.v24i3.18682

By:

Shekarchian, Sajjad;
Eghtedardoost, Marzieh;
Golshahi, Hannaneh;
Behrouzfar, Helia;
Fakhroueian, Zahra;
Yaraee, Roya

Publication type:

Article

The dual roles of human PYHIN family proteins in cancer: mechanisms and therapeutic implications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576674

By:

Zeng, Shuyan;
Zhou, Zhiyong;
Li, Yi;
Wu, Di;
Xiao, Qiuyun;
Peng, Huiyun

Publication type:

Article

SDC1 is a critical transmembrane proteoglycan in breast cancer.

Published in:

World Journal of Surgical Oncology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12957-025-03840-z

By:

Mei, Yingying;
Zhao, Lantao;
Zhou, Na

Publication type:

Article

Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03801-2

By:

Wang, Kai;
Shen, Xihao;
Wu, Jiyue;
Bi, Qing;
Gao, Zihao;
Sun, Zejia;
Wang, Wei

Publication type:

Article

An energy metabolism-related signature relevant to the tumor immune microenvironment in HNSCC.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02652-7

By:

Zhu, Kaiyu;
Bai, Yang;
Lin, Changwei;
Song, Guilin;
Chen, Yifei

Publication type:

Article

Mendelian randomization analysis reveals potential association between allergic rhinitis and nasopharyngeal carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02658-1

By:

Bao, Qingfu;
Zou, Jianjun;
Wang, Changyang;
Wang, Haiying

Publication type:

Article

Effects of ER-phagy regulatory genes on the microenvironment of hepatocellular carcinoma: a comprehensive analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02649-2

By:

Zhao, Rongchang;
Ding, Dan;
Bao, Minhui;
Ding, Yan;
Ding, Rongjie;
Liu, Jun;
Li, Yu;
Zhu, Chunrong

Publication type:

Article

The integrated single-cell analysis interpret the lactate metabolism-driven immune suppression in triple-negative breast cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02605-0

By:

Gao, Xinhai;
Wang, Tianhua;
Liu, Cun;
Li, Ye;
Zhang, Wenfeng;
Zhang, Minpu;
Yao, Yan;
Gao, Chundi;
Liu, Ruijuan;
Sun, Changgang

Publication type:

Article

Specific signaling pathways mediated programmed cell death in tumor microenvironment and target therapies.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02592-2

By:

Sun, Chengpeng;
Gui, Jiawei;
Sheng, Yilei;
Huang, Le;
Zhu, Xingen;
Huang, Kai

Publication type:

Article

Sialyltransferase gene signature as a predictor of prognosis and therapeutic response in kidney renal clear cell carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02566-4

By:

Liu, Huiyu;
Zhou, Changwei;
Yan, Zaichun;
Yang, Hairong;
Zhao, Yun;
Tian, Rui;
Bo, Xuejun;
Zhao, Leizuo;
Ren, Wei

Publication type:

Article

Integrating multi-omics data to identify the role of Aggrephagy-related genes in tumor microenvironment and key tumorigenesis factors of GB from the perspective of single-cell sequencing.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02431-4

By:

Chen, Zipei;
Zhang, Shengke;
Jiang, Chenglu;
Jiang, Lai;
Chen, Haiqing;
Huang, Jinbang;
Liu, Jie;
Yang, Guanhu;
Luo, Xiufang;
Chi, Hao;
Fu, Jiangping

Publication type:

Article

Tissue-resident microbiota signature in nasopharyngeal carcinoma.

Published in:

Microbiome, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40168-025-02114-w

By:

Tan, Xi-Rong;
Qiao, Han;
Li, Ying-Qing;
Jiang, Wei;
Huang, Sheng-Yan;
Gong, Sha;
Li, Wen-Fei;
Tang, Ling-Long;
Zhou, Guan-Qun;
Liang, Ye-Lin;
Li, Hui;
He, Qing-Mei;
Bai, Jie-Wen;
Ye, Ming-Liang;
Wang, Jing-Yun;
Huang, Sai-Wei;
Li, Jun-Yan;
Gan, Chun-Qiao;
Li, Ying-Qin;
Zhao, Yin

Publication type:

Article

青蒿素及其衍生物在癌症治疗中作用机制的研究进展.

Published in:

Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2025, v. 46, n. 4, p. 1, doi. 10.12259/j.issn.2095-610X.S20250401

By:

曾维兴;
何永文

Publication type:

Article

Advances and Challenges in Human 3D Solid Tumor Models.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 20, p. 1, doi. 10.1002/adfm.202419912

By:

Natesh, Naveen R.;
Varghese, Shyni

Publication type:

Article

Integrative single-cell RNA sequencing and bulk RNA sequencing reveals the characteristics of glutathione metabolism and protective role of GSTA4 gene in pancreatic cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571431

By:

Jia, Xinya;
Zhang, Qiang;
Wang, Zhe;
Cao, Jianliang;
Song, Anran;
Lan, Chao;
Hu, Yuepeng

Publication type:

Article