Title: Electrochemical chiral recognition of tryptophan using a glassy carbon electrode modified with β-cyclodextrin and graphene.
Authors: Feng, Wanlian; Liu, Chao; Lu, Shaoyou; Zhang, Chuyi; Zhu, Xiaohua; Liang, Yong; Nan, Junmin
Abstract: We report on a method for electrochemical enantioselective recognition of tryptophan (Trp) enantiomers. It is based on competitive host-guest interaction between a deoxy-(2-aminoethylamino)-β-cyclodextrin (CD) bound to graphene nanosheets and the Cu(II) complexes of the Trp enantiomers via a ligand exchange mechanism. Chiral recognition was investigated via cyclic voltammetry and electrochemical impedance spectroscopy. The results reveal that the CD bound to graphene displays a stronger interaction with the Cu(II) complex of L-Trp than to that of D-Trp. The method was applied to the determination of the ratio of Trp enantiomers in mixtures. [Figure not available: see fulltext.]
Subjects: CHIRALITY; TRYPTOPHAN; CARBON electrodes; CYCLODEXTRINS; GRAPHENE; ENANTIOSELECTIVE catalysis; ELECTROCHEMISTRY
Publication: Microchimica Acta, 2014, Vol 181, Issue 5/6, p501
ISSN: 0026-3672
Publication type: Academic Journal
DOI: 10.1007/s00604-014-1174-0

Electrochemical chiral recognition of tryptophan using a glassy carbon electrode modified with β-cyclodextrin and graphene.

Feng, Wanlian; Liu, Chao; Lu, Shaoyou; Zhang, Chuyi; Zhu, Xiaohua; Liang, Yong; Nan, Junmin